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1. 发明申请

US20120170820A1 METHODS AND APPARATUS FOR COMPARING 3D AND 2D IMAGE DATA 审中-公开
标题翻译：用于比较3D和2D图像数据的方法和装置
公开(公告)号：US20120170820A1
公开(公告)日：2012-07-05
申请号：US13303445
申请日：2011-11-23
申请人： Jerome Declerck , Matthew David Kelly , Christian Mathers
发明人： Jerome Declerck , Matthew David Kelly , Christian Mathers
IPC分类号： G06K9/00
CPC分类号： G06T7/30 , G06T2207/10104 , G06T2207/10108
摘要： In a method or apparatus of comparing two image data sets from medical imaging data of a subject, a first, three-dimensional image data set of the subject is obtained. A second, two-dimensional image data set of the subject is also obtained. The first data set is registered with the second data set. Data from the first, three-dimensional image data set is processed to determine a voxel in the first data set which corresponds to a given pixel in the second, two-dimensional image data set.
摘要翻译：在从对象的医学成像数据中比较两个图像数据集的方法或装置中，获得被摄体的第一，三维图像数据集。还获得了被摄体的第二个二维图像数据集。第一数据集被注册到第二数据集。来自第一，三维图像数据集的数据被处理以确定与第二二维图像数据集中的给定像素相对应的第一数据集中的体素。

2. 发明申请

US20100092052A1 METHODS AND APPARATUS FOR ANALYZING MEDICAL IMAGING DATA 有权
标题翻译：用于分析医学成像数据的方法和装置
公开(公告)号：US20100092052A1
公开(公告)日：2010-04-15
申请号：US12575653
申请日：2009-10-08
申请人： Jerome Declerck , Timor Kadir , Matthew David Kelly
发明人： Jerome Declerck , Timor Kadir , Matthew David Kelly
IPC分类号： G06K9/00
CPC分类号： A61B6/12 , A61B5/20 , A61B5/201 , A61B5/7239 , A61B6/037 , G01T1/00 , G06F19/00 , G06T7/0016 , G06T2207/10104 , G06T2207/30084
摘要： In a method and apparatus for analyzing medical imaging data of a subject from an imaging modality using a tracer, data from detection of tracer emission events at least one region of a scanned imaging volume are obtained, and the data processed to establish sub-periods or time points within a scan period for the emission events. A rate of change of emission events per unit time for a given region is then calculated, for example by obtaining a number of emission events in each sub-period in the given region, and fitting a line through the values for the sub-periods.
摘要翻译：在使用示踪剂从成像模态分析被检体的医学成像数据的方法和装置中，获得来自扫描成像体积的至少一个区域的示踪剂发射事件的检测的数据，并且处理数据以建立子周期或在发射事件的扫描周期内的时间点。然后计算给定区域的每单位时间的排放事件的变化率，例如通过获得给定区域中的每个子周期中的排放事件的数量，以及通过子周期的值拟合一行。

3. 发明授权

US08755574B2 Method and apparatus for calibrating medical image data 有权
标题翻译：用于校准医学图像数据的方法和装置
公开(公告)号：US08755574B2
公开(公告)日：2014-06-17
申请号：US12760639
申请日：2010-04-15
申请人： Jerome Declerck , Matthew David Kelly
发明人： Jerome Declerck , Matthew David Kelly
IPC分类号： G06K9/00
CPC分类号： A61B6/037 , A61B6/583 , G06F19/00 , H04N17/002
摘要： In a method and apparatus for calibrating image data from a given medical imaging protocol, reference image data is obtained from a scan of a reference object using the medical imaging protocol, and the obtained reference image data of the reference object is compared to standard reference image data for the reference object. The obtained reference image data is then modified to reduce an error between the obtained reference image data and the standard reference image data. Subject image data id then obtained from a scan of a subject using the medical imaging protocol, and modified based on the modified reference image data. A value of a variable is obtained from the modified subject image data, for display with unmodified subject image data.
摘要翻译：在用于校准来自给定医学成像协议的图像数据的方法和装置中，使用医学成像协议从参考对象的扫描获得参考图像数据，并将获得的参考对象的参考图像数据与标准参考图像参考对象的数据。然后修改所获得的参考图像数据以减少所获得的参考图像数据与标准参考图像数据之间的误差。然后从使用医学成像协议的对象的扫描获得的主题图像数据id，并且基于修改的参考图像数据进行修改。从修改的被摄体图像数据获得变量的值，以便用未修改的被摄体图像数据进行显示。

4. 发明申请

US20100290680A1 METHOD AND APPARATUS FOR CALIBRATING MEDICAL IMAGE DATA 有权
标题翻译：用于校准医学图像数据的方法和装置
公开(公告)号：US20100290680A1
公开(公告)日：2010-11-18
申请号：US12760639
申请日：2010-04-15
申请人： Jerome Declerck , Matthew David Kelly
发明人： Jerome Declerck , Matthew David Kelly
IPC分类号： G06K9/00
CPC分类号： A61B6/037 , A61B6/583 , G06F19/00 , H04N17/002
摘要： In a method and apparatus for calibrating image data from a given medical imaging protocol, reference image data is obtained from a scan of a reference object using the medical imaging protocol, and the obtained reference image data of the reference object is compared to standard reference image data for the reference object. The obtained reference image data is then modified to reduce an error between the obtained reference image data and the standard reference image data. Subject image data id then obtained from a scan of a subject using the medical imaging protocol, and modified based on the modified reference image data. A value of a variable is obtained from the modified subject image data, for display with unmodified subject image data.
摘要翻译：在用于校准来自给定医学成像协议的图像数据的方法和装置中，使用医学成像协议从参考对象的扫描获得参考图像数据，并将获得的参考对象的参考图像数据与标准参考图像参考对象的数据。然后修改所获得的参考图像数据以减少所获得的参考图像数据与标准参考图像数据之间的误差。然后从使用医学成像协议的对象的扫描获得的主题图像数据id，并且基于修改的参考图像数据进行修改。从修改的被摄体图像数据获得变量的值，以便用未修改的被摄体图像数据进行显示。

5. 发明授权

US08693741B2 Methods and apparatus for analyzing medical imaging data 有权
标题翻译：用于分析医学成像数据的方法和装置
公开(公告)号：US08693741B2
公开(公告)日：2014-04-08
申请号：US12575653
申请日：2009-10-08
申请人： Jerome Declerck , Timor Kadir , Matthew David Kelly
发明人： Jerome Declerck , Timor Kadir , Matthew David Kelly
IPC分类号： G06K9/00 , G06K9/62
CPC分类号： A61B6/12 , A61B5/20 , A61B5/201 , A61B5/7239 , A61B6/037 , G01T1/00 , G06F19/00 , G06T7/0016 , G06T2207/10104 , G06T2207/30084
摘要： In a method and apparatus for analyzing medical imaging data of a subject from an imaging modality using a tracer, data from detection of tracer emission events at least one region of a scanned imaging volume are obtained, and the data processed to establish sub-periods or time points within a scan period for the emission events. A rate of change of emission events per unit time for a given region is then calculated, for example by obtaining a number of emission events in each sub-period in the given region, and fitting a line through the values for the sub-periods.
摘要翻译：在使用示踪剂从成像模态分析被检体的医学成像数据的方法和装置中，获得来自扫描成像体积的至少一个区域的示踪剂发射事件的检测的数据，并且处理数据以建立子周期或在发射事件的扫描周期内的时间点。然后计算给定区域的每单位时间的排放事件的变化率，例如通过获得给定区域中的每个子周期中的排放事件的数量，以及通过子周期的值拟合一行。

6. 发明授权

US08498492B2 Methods of analyzing a selected region of interest in medical image data 有权
标题翻译：分析医学图像数据中所选择的感兴趣区域的方法
公开(公告)号：US08498492B2
公开(公告)日：2013-07-30
申请号：US12847344
申请日：2010-07-30
申请人： Jerome Declerck , Timor Kadir , Matthew David Kelly
发明人： Jerome Declerck , Timor Kadir , Matthew David Kelly
IPC分类号： G06K9/68
CPC分类号： G06T7/0012 , G06T2207/10104 , G06T2207/10108 , G06T2207/20072 , G06T2207/20104 , G06T2207/30056
摘要： In methods and an apparatus for analyzing a selected region of interest in medical image data of a subject, an initial image data set is obtained, and the initial image data set is filtered to generate a filtered data set. The filtering includes computing, for each voxel of the initial image data set, a value of intensity for a standardized volume of interest centered on that voxel. A user selection of a region of interest in the initial image data set is registered, and from the filtered image data set a value of intensity for the selected region of interest is computed.
摘要翻译：在用于分析对象的医学图像数据中的所选择的感兴趣区域的方法和装置中，获得初始图像数据集，并且对初始图像数据集进行滤波以生成滤波数据集。滤波包括对于初始图像数据集的每个体素计算针对以该体素为中心的标准化感兴趣体积的强度值。注册初始图像数据集中的感兴趣区域的用户选择，并且从滤波图像数据集计算所选择的感兴趣区域的强度值。

7. 发明申请

US20110026797A1 METHODS OF ANALYZING A SELECTED REGION OF INTEREST IN MEDICAL IMAGE DATA 有权
标题翻译：分析选择的医疗图像数据区域的方法
公开(公告)号：US20110026797A1
公开(公告)日：2011-02-03
申请号：US12847344
申请日：2010-07-30
申请人： Jerome Declerck , Timor Kadir , Matthew David Kelly
发明人： Jerome Declerck , Timor Kadir , Matthew David Kelly
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T2207/10104 , G06T2207/10108 , G06T2207/20072 , G06T2207/20104 , G06T2207/30056
摘要： In methods and an apparatus for analyzing a selected region of interest in medical image data of a subject, an initial image data set is obtained, and the initial image data set is filtered to generate a filtered data set. The filtering includes computing, for each voxel of the initial image data set, a value of intensity for a standardized volume of interest centered on that voxel. A user selection of a region of interest in the initial image data set is registered, and from the filtered image data set a value of intensity for the selected region of interest is computed.
摘要翻译：在用于分析对象的医学图像数据中的所选择的感兴趣区域的方法和装置中，获得初始图像数据集，并且对初始图像数据集进行滤波以生成滤波数据集。滤波包括对于初始图像数据集的每个体素计算针对以该体素为中心的标准化感兴趣体积的强度值。注册初始图像数据集中的感兴趣区域的用户选择，并且从滤波图像数据集计算所选择的感兴趣区域的强度值。

8. 发明授权

US09042620B2 Method and system for multi-organ segmentation using learning-based segmentation and level set optimization 有权
标题翻译：使用基于学习的分割和水平集优化的多器官分割的方法和系统
公开(公告)号：US09042620B2
公开(公告)日：2015-05-26
申请号：US13416508
申请日：2012-03-09
申请人： Timo Kohlberger , Michal Sofka , Jens Wetzl , Jingdan Zhang , Shaohua Kevin Zhou , Neil Birkbeck , Jerome Declerck , Jens Kaftan
发明人： Timo Kohlberger , Michal Sofka , Jens Wetzl , Jingdan Zhang , Shaohua Kevin Zhou , Neil Birkbeck , Jerome Declerck , Jens Kaftan
IPC分类号： G06K9/00 , G06T7/00 , G06K9/62
CPC分类号： G06T7/0083 , G06K9/6209 , G06T7/12 , G06T2207/10081 , G06T2207/20081 , G06T2207/20161 , G06T2207/30048 , G06T2207/30084
摘要： A method and system for automatic multi-organ segmentation in a 3D image, such as a 3D computed tomography (CT) volume using learning-base segmentation and level set optimization is disclosed. A plurality of meshes are segmented in a 3D medical image, each mesh corresponding to one of a plurality of organs. A level set in initialized by converting each of the plurality of meshes to a respective signed distance map. The level set optimized by refining the signed distance map corresponding to each one of the plurality of organs to minimize an energy function.
摘要翻译：公开了一种3D图像自动多器官分割的方法和系统，例如使用学习型基础分割和级别集优化的3D计算机断层摄影（CT）体积。在3D医学图像中分割多个网格，每个网格对应于多个器官中的一个。通过将多个网格中的每一个转换为相应的带符号距离图来初始化的级别。通过精化对应于多个器官中的每一个的有符号距离图来最优化能量函数来优化的级别集合。

9. 发明授权

US08078258B2 Assessment of vascular compartment volume for PET modelling 有权
标题翻译： PET建模血管隔室体积评估
公开(公告)号：US08078258B2
公开(公告)日：2011-12-13
申请号：US12121279
申请日：2008-05-15
申请人： Jerome Declerck , Kevin Scott Hakl
发明人： Jerome Declerck , Kevin Scott Hakl
IPC分类号： A61B5/05
CPC分类号： G01R33/481 , A61B5/055 , A61B6/037 , A61B6/5247 , G01R33/281
摘要： A method is described for acquiring and analysing the data produced by Positron Emission Tomography (PET), which method provides for an accurate estimation of vascular compartment volume, VB. An MRI scan and the PET scan is performed simultaneously and the results of the former is used to derive a value for VB. The value so derived is then used in pharmacokinetic modelling along with the results of the functional scan.
摘要翻译：描述了一种用于获取和分析由正电子发射断层扫描（PET）产生的数据的方法，该方法提供了对血管室容积的准确估计。 MRI扫描和PET扫描同时进行，前者的结果用于导出VB的值。然后将所得的值与功能扫描的结果一起用于药代动力学建模。

10. 发明申请

US20140270438A1 METHOD FOR LOCALIZATION OF AN EPILEPTIC FOCUS IN NEUROIMAGING 有权
标题翻译：用于局部化神经元的神经元聚焦方法
公开(公告)号：US20140270438A1
公开(公告)日：2014-09-18
申请号：US14208315
申请日：2014-03-13
申请人： Jerome Declerck , Kinda Anna Saddi
发明人： Jerome Declerck , Kinda Anna Saddi
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , A61B6/037 , A61B6/5217 , G06T7/0016 , G06T7/254 , G06T2207/10088 , G06T2207/10104 , G06T2207/10108 , G06T2207/30016
摘要： In a method for localizing a candidate foci in neuroimaging, two images are acquired, one being a baseline (interictal) image and another being an intervention (ictal) image. The two images are aligned and the intensities of the images are normalized. A difference image is calculated by subtracting the baseline (interictal) image from the intervention (ictal) image. The difference image is normalized and regions of interest are selected as candidate foci.
摘要翻译：在用于定位神经成像中的候选病灶的方法中，获取两个图像，一个是基线（中间）图像，另一个是干预（ictal）图像。两个图像对齐，图像的强度被归一化。通过从干预（ictal）图像中减去基线（中间）图像来计算差异图像。差分图像被归一化，并且将感兴趣的区域选择为候选焦点。

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