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1. 发明授权

US09050069B2 Thermocouple-controlled catheter cooling system 有权
标题翻译：热电偶控制导管冷却系统
公开(公告)号：US09050069B2
公开(公告)日：2015-06-09
申请号：US12122436
申请日：2008-05-16
申请人： Jean-Pierre Lalonde , Dan Wittenberger , Marwan Abboud , Constantin Bogdan Ciobotaru , Ramin Sabbaghe-Kermani
发明人： Jean-Pierre Lalonde , Dan Wittenberger , Marwan Abboud , Constantin Bogdan Ciobotaru , Ramin Sabbaghe-Kermani
IPC分类号： A61B18/02 , A61B18/00 , A61M25/01
CPC分类号： A61B18/02 , A61B2018/00023 , A61B2018/0022 , A61B2018/00797 , A61B2018/00821 , A61B2018/0212 , A61B2018/0262 , A61M25/0136
摘要： The present invention provides a medical system, including a catheter defining an injection lumen, a chamber in fluid communication with the injection lumen, and an exhaust lumen in fluid communication with the chamber; a first temperature sensor positioned in the exhaust lumen proximal to the chamber; a second temperature sensor positioned in the chamber; and a console in electrical communication with the first and second temperature sensors, the controller modifying coolant flow through the medical device based at least in part upon a signal received from the first and second temperature sensor. The system may further include a thermally-conductive element circumscribing a substantial portion of the exhaust lumen proximal to the chamber, where the first temperature sensor is mounted to the thermally-conductive element, and the thermally-conductive element may include at least one of a braid, coil, and band.
摘要翻译：本发明提供了一种医疗系统，其包括限定注射腔的导管，与注射腔流体连通的腔室和与腔室流体连通的排气腔; 定位在靠近所述腔室的所述排气腔内的第一温度传感器; 位于所述室中的第二温度传感器; 以及与所述第一和第二温度传感器电连通的控制台，所述控制器至少部分地基于从所述第一和第二温度传感器接收的信号来改变通过所述医疗设备的冷却剂流动。该系统还可以包括限定靠近腔室的排气腔的主要部分的导热元件，其中第一温度传感器安装到导热元件，并且导热元件可以包括以下中的至少一个：辫子，线圈和乐队。

2. 发明授权

US09314588B2 Systems and methods for variable injection flow 有权
标题翻译：可变注射流量的系统和方法
公开(公告)号：US09314588B2
公开(公告)日：2016-04-19
申请号：US13300931
申请日：2011-11-21
申请人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir Seraj
发明人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir Seraj
IPC分类号： A61B18/02 , A61M25/00 , A61M39/28 , A61M39/22 , A61M25/01 , A61B18/00
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/00023 , A61B2018/00095 , A61B2018/00101 , A61B2018/00202 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , A61M25/0029 , A61M25/007 , A61M39/22 , A61M39/28 , A61M2025/0025 , A61M2025/0079 , A61M2025/0175 , Y10T137/0318
摘要： Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.
摘要翻译：公开了用于可控地变化的流体流动的系统和方法，其提供修改可用于流体流动的流体输送导管的有效横截面面积的能力。因此，选择性地控制这些构造允许在流体输送压力保持相同时根据需要调节流体流动。本文提供的其它配置允许选择性地操纵在单个过程期间用医疗装置实现的足迹或治疗模式，否定了去除和插入多个装置以实现治疗几何形状或特征的相同变化的需要。

3. 发明授权

US06589234B2 Cryogenic medical device with high pressure resistance tip 有权
标题翻译：具有高耐压端头的低温医疗器械
公开(公告)号：US06589234B2
公开(公告)日：2003-07-08
申请号：US09965208
申请日：2001-09-27
申请人： Jean-Pierre Lalonde , Marwan Abboud , Constantin Bogdan Ciobotaru
发明人： Jean-Pierre Lalonde , Marwan Abboud , Constantin Bogdan Ciobotaru
IPC分类号： A61B1818
CPC分类号： A61B18/02 , A61B2018/0212 , A61B2018/0268
摘要： The present invention provides a medical device to cold treat desired regions. An injection tube with an open distal end is disposed inside of a catheter tube, defining a return lumen therein. A supply of cryogenic fluid, regulated by a controller mechanism coupled to the device, flows through the injection tube and into the distal tip portion of the catheter tube, whereupon the fluid is returned from the catheter through the return lumen. The expansion and evaporation of cryogenic fluid inside the device serves to cool the surrounding areas external to and proximate the distal end of the device. An additional restriction tube is provided in the length of the catheter tube to regulate the pressure of the flow of cryogen therethrough so as to create higher operating pressures in the distal end of the device and thereby enhance the cooling power and temperature stability of the device at a lower range of fluid flow rates without reaching the triple point of the cryogenic fluid.
摘要翻译：本发明提供一种用于冷处理所需区域的医疗装置。具有开口远端的注射管设置在导管管内部，在其中限定回流腔。由连接到装置的控制器机构调节的低温流体的供应流过注射管并进入导管管的远侧末端部分，于是流体从导管通过返回内腔返回。装置内的低温流体的膨胀和蒸发用于冷却装置的远端外部和附近的周围区域。在导管的长度上设置一个附加的限制管，用于调节制冷剂流过的压力，从而在装置的远端产生更高的操作压力，从而提高装置的冷却功率和温度稳定性较低的流体流速范围，而不达到低温流体的三重点。

4. 发明授权

US09320871B2 Systems and methods for variable injection flow 有权
公开(公告)号：US09320871B2
公开(公告)日：2016-04-26
申请号：US13409875
申请日：2012-03-01
申请人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir-Seraj
发明人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir-Seraj
IPC分类号： A61B18/02 , A61M25/00 , A61M39/28 , A61M39/22 , A61M25/01 , A61B18/00
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/00023 , A61B2018/00095 , A61B2018/00101 , A61B2018/00202 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , A61M25/0029 , A61M25/007 , A61M39/22 , A61M39/28 , A61M2025/0025 , A61M2025/0079 , A61M2025/0175 , Y10T137/0318
摘要： Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.

5. 发明授权

US09352121B2 Systems and methods for variable injection flow 有权
公开(公告)号：US09352121B2
公开(公告)日：2016-05-31
申请号：US13409646
申请日：2012-03-01
申请人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir-Seraj
发明人： Regina E. Groves , Jean-Pierre Lalonde , Timothy G. Laske , Claudia Lueckge , Dan Wittenberger , Ramin Sabbaghe-Kermani , Mahmoud Kabir-Seraj
IPC分类号： A61B18/02 , A61M25/00 , A61M39/28 , A61M39/22 , A61M25/01 , A61B18/00
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/00023 , A61B2018/00095 , A61B2018/00101 , A61B2018/00202 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , A61M25/0029 , A61M25/007 , A61M39/22 , A61M39/28 , A61M2025/0025 , A61M2025/0079 , A61M2025/0175 , Y10T137/0318
摘要： Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.

6. 发明授权

US07914524B2 Surgical clamp having trasmurality assessment capabilities 有权
标题翻译：手术夹具具有纹理评估能力
公开(公告)号：US07914524B2
公开(公告)日：2011-03-29
申请号：US11709040
申请日：2007-02-21
申请人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
发明人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00026 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/1465
摘要： A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation mechanism is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.
摘要翻译：提供了具有用于致动一对相对的钳口构件的装置的医疗装置。钳口构件可从第一位置相对于彼此移动，其中钳口构件相对于彼此以间隔开的关系设置到第二位置，其中钳口构件协作以在其间抓握组织。消融机构连接到至少一个夹爪构件，使得钳口构件能够通过夹在其间夹持的组织进行消融能量。

7. 发明授权

US07819860B2 Surgical clamp having trasmurality assessment capabilities 有权
标题翻译：手术夹具具有纹理评估能力
公开(公告)号：US07819860B2
公开(公告)日：2010-10-26
申请号：US10841955
申请日：2004-05-07
申请人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
发明人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
IPC分类号： A61B18/02
CPC分类号： A61B17/2812 , A61B5/0408 , A61B17/122 , A61B17/282 , A61B17/29 , A61B18/02 , A61B18/0218 , A61B2017/00026 , A61B2017/00084 , A61B2017/00243 , A61B2017/00738 , A61B2017/2905 , A61B2017/2931 , A61B2017/2944 , A61B2018/00011 , A61B2018/00577 , A61B2018/00744 , A61B2018/00791 , A61B2018/00839 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/145
摘要： A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation mechanism is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.
摘要翻译：提供了具有用于致动一对相对的钳口构件的装置的医疗装置。钳口构件可从第一位置相对于彼此移动，其中钳口构件相对于彼此以间隔开的关系设置到第二位置，其中钳口构件协作以在其间抓握组织。消融机构连接到至少一个夹爪构件，使得钳口构件能够通过夹在其间夹持的组织进行消融能量。

8. 发明授权

US06635053B1 Cooling system 有权
标题翻译：冷却系统
公开(公告)号：US06635053B1
公开(公告)日：2003-10-21
申请号：US09638208
申请日：2000-08-11
申请人： Jean-Pierre Lalonde , Marwan Abboud , Rachid Mahrouche , Dan Wittenberger
发明人： Jean-Pierre Lalonde , Marwan Abboud , Rachid Mahrouche , Dan Wittenberger
IPC分类号： A61B1818
CPC分类号： A61B18/02 , A61B2017/00084 , A61B2017/00092 , A61B2017/00119 , A61B2017/00199 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要： A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.
摘要翻译：低温医疗系统包括在连接点处可连接到医疗装置的医疗装置和控制台。控制台控制医疗设备的温度。所述控制台包括第一冷却系统，所述第一冷却系统沿着冷却剂供应管线在第一温度下将冷却剂引导至所述医疗设备;以及第二冷却系统，在所述冷却剂到达所述连接点之前将所述冷却剂供应管线内的冷却剂冷却至低于所述第一温度的温

9. 发明授权

US07981110B2 Surgical clamp having trasmurality assessment capabilities 有权
公开(公告)号：US07981110B2
公开(公告)日：2011-07-19
申请号：US11709067
申请日：2007-02-21
申请人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
发明人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00026 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/1465
摘要： A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation mechanism is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.

10. 发明授权

US07955325B2 Surgical clamp having transmurality assessment capabilities 有权
公开(公告)号：US07955325B2
公开(公告)日：2011-06-07
申请号：US11708927
申请日：2007-02-21
申请人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
发明人： Dan Wittenberger , Daniel Nahon , Marwan Abboud , Jean-Pierre Lalonde , Cristian Petre , Réal Ste-Marie , Sean Carroll , Allan Skanes , Alan H. Menkis
IPC分类号： A61B18/02
CPC分类号： A61B17/2812 , A61B5/0408 , A61B17/122 , A61B17/282 , A61B17/29 , A61B18/02 , A61B18/0218 , A61B2017/00026 , A61B2017/00084 , A61B2017/00243 , A61B2017/00738 , A61B2017/2905 , A61B2017/2931 , A61B2017/2944 , A61B2018/00011 , A61B2018/00577 , A61B2018/00744 , A61B2018/00791 , A61B2018/00839 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/145
摘要： A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation mechanism is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.

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