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1. 发明申请

US20050192505A1 Method for discriminating between ventricular and supraventricular arrhythmias 有权
标题翻译：区分心室和室上性心律失常的方法
公开(公告)号：US20050192505A1
公开(公告)日：2005-09-01
申请号：US11120258
申请日：2005-05-02
申请人： Alan Ostroff , Jay Warren , Gust Bardy
发明人： Alan Ostroff , Jay Warren , Gust Bardy
IPC分类号： A61N1/39 , A61N1/362
CPC分类号： A61N1/3956 , A61B5/0422 , A61B5/04525 , A61B5/0464 , A61B5/686 , A61N1/3925 , A61N1/3987
摘要： The present invention is directed toward a detection architecture for use in implantable cardiac rhythm devices. The detection architecture of the present invention provides methods and devices for discriminating between arrhythmias. Moreover, by exploiting the enhanced specificity in the origin of the identified arrhythmia, the detection architecture can better discriminate between rhythms appropriate for device therapy and those that are not.
摘要翻译：本发明涉及用于可植入心律装置的检测架构。本发明的检测架构提供了用于区分心律失常的方法和装置。此外，通过利用识别的心律失常起源的增强的特异性，检测架构可以更好地区分适合于设备治疗的节律和不适合的治疗节律。

2. 发明申请

US20060167504A1 Devices for adapting charge initiation for an implantable cardioverter-defibrillator 有权
标题翻译：适用于植入式心律转复除颤器的充电开始装置
公开(公告)号：US20060167504A1
公开(公告)日：2006-07-27
申请号：US11043012
申请日：2005-01-25
申请人： Jay Warren , Gust Bardy
发明人： Jay Warren , Gust Bardy
IPC分类号： A61N1/39
CPC分类号： A61N1/3943 , A61N1/3956
摘要： The present invention is directed toward devices configured to perform an adaptive method for initiating the charging and delivering therapy to treat patient's experiencing recurrent non-sustained arrhythmic events. The adaptive methods of the allow accounting for the persistence of an arrhythmia prior to initiating the charging sequence to deliver therapy.
摘要翻译：本发明涉及被配置为执行用于启动充电和递送治疗以治疗患者经历复发性非持续性心律不齐事件的自适应方法的装置。允许的适应性方法考虑到在开始充电序列之前持续的心律失常以递送治疗。

3. 发明申请

US20060167503A1 Method for adapting charge initiation for an implantable cardioverter-defibrillator 有权
标题翻译：适用于植入式心律转复除颤器的充电起始的方法
公开(公告)号：US20060167503A1
公开(公告)日：2006-07-27
申请号：US11042911
申请日：2005-01-25
申请人： Jay Warren , Gust Bardy
发明人： Jay Warren , Gust Bardy
IPC分类号： A61N1/39
CPC分类号： A61N1/3621 , A61N1/3943 , A61N1/3956
摘要： The present invention is directed toward an adaptive method for initiating the charging and delivering therapy to treat patient's experiencing recurrent non-sustained arrhythmic events. The adaptive methods of the present invention allow accounting for the persistence of an arrhythmia prior to initiating the charging sequence to deliver therapy.
摘要翻译：本发明涉及用于启动充电和递送治疗以治疗患者经历复发性非持续性心律不齐事件的适应性方法。本发明的适应性方法允许在启动充电序列之前考虑心律失常的持续性以递送治疗。

4. 发明申请

US20050192507A1 Multiple electrode vectors for implantable cardiac treatment devices 有权
公开(公告)号：US20050192507A1
公开(公告)日：2005-09-01
申请号：US11120284
申请日：2005-05-02
申请人： Jay Warren , Gust Bardy
发明人： Jay Warren , Gust Bardy
IPC分类号： A61B5/024 , A61B5/0402 , A61B5/042 , A61B5/0424 , A61B5/0428 , A61B5/07 , A61N1/362 , A61N1/368 , A61N1/39
CPC分类号： A61B5/0424 , A61B5/0402 , A61B5/042 , A61B5/04288 , A61B5/076 , A61B5/7207 , A61N1/3622 , A61N1/3925
摘要： The implantable cardiac treatment system of the present invention is capable of choosing the most appropriate electrode vector to sense within a particular patient. In certain embodiments, the implantable cardiac treatment system determines the most appropriate electrode vector for continuous sensing based on which electrode vector results in the greatest signal amplitude, or some other useful metric such as signal-to-noise ratio (SNR). The electrode vector possessing the highest quality as measured using the metric is then set as the default electrode vector for sensing. Additionally, in certain embodiments of the present invention, a next alternative electrode vector is selected based on being generally orthogonal to the default electrode vector. In yet other embodiments of the present invention, the next alternative electrode vector is selected based on possessing the next highest quality metric after the default electrode vector. In some embodiments, if analysis of the default vector is ambiguous, the next alternative electrode vector is analyzed to reduce ambiguity.

5. 发明申请

US20050049644A1 Multiple electrode vectors for implantable cardiac treatment devices 有权
标题翻译：用于可植入心脏治疗装置的多个电极载体
公开(公告)号：US20050049644A1
公开(公告)日：2005-03-03
申请号：US10901258
申请日：2004-07-27
申请人： Jay Warren , Gust Bardy
发明人： Jay Warren , Gust Bardy
IPC分类号： A61B5/024 , A61B5/0402 , A61B5/042 , A61B5/0424 , A61B5/0428 , A61B5/07 , A61N1/362 , A61N1/368 , A61N1/39
CPC分类号： A61B5/0424 , A61B5/0402 , A61B5/042 , A61B5/04288 , A61B5/076 , A61B5/7207 , A61N1/3622 , A61N1/3925
摘要： The implantable cardiac treatment system of the present invention is capable of choosing the most appropriate electrode vector to sense within a particular patient. In certain embodiments, the implantable cardiac treatment system determines the most appropriate electrode vector for continuous sensing based on which electrode vector results in the greatest signal amplitude, or some other useful metric such as signal-to-noise ratio (SNR). The electrode vector possessing the highest quality as measured using the metric is then set as the default electrode vector for sensing. Additionally, in certain embodiments of the present invention, a next alternative electrode vector is selected based on being generally orthogonal to the default electrode vector. In yet other embodiments of the present invention, the next alternative electrode vector is selected based on possessing the next highest quality metric after the default electrode vector. In some embodiments, if analysis of the default vector is ambiguous, the next alternative electrode vector is analyzed to reduce ambiguity.
摘要翻译：本发明的可植入心脏治疗系统能够选择最合适的电极载体以在特定患者体内感测。在某些实施例中，可植入心脏治疗系统基于哪个电极向量导致最大的信号幅度或诸如信噪比（SNR）的一些其他有用的度量来确定用于连续感测的最合适的电极向量。使用度量测量的具有最高质量的电极矢量然后被设置为用于感测的默认电极矢量。另外，在本发明的某些实施例中，基于大致正交于默认电极向量来选择下一个备选电极矢量。在本发明的其它实施例中，基于在默认电极向量之后拥有下一个最高质量度量来选择下一个备选电极矢量。在一些实施例中，如果默认矢量的分析是不明确的，则分析下一个替代电极矢量以减少模糊度。

6. 发明授权

US4624260A Pacemaker with conditional atrial tracking capability 失效
标题翻译：起搏器具有条件性心房跟踪能力
公开(公告)号：US4624260A
公开(公告)日：1986-11-25
申请号：US731581
申请日：1985-05-07
申请人： Ross G. Baker, Jr. , Richard V. Calfee , Richard S. Sanders , Joe Vandegriff , Jay Warren
发明人： Ross G. Baker, Jr. , Richard V. Calfee , Richard S. Sanders , Joe Vandegriff , Jay Warren
IPC分类号： A61N1/365 , A61N1/362 , A61N1/372 , A61N1/36
CPC分类号： A61N1/3622
摘要： An implantable microprocessor-controlled dual chamber heart pacemaker is programmed to control the timing of the pacing of the ventricle in response to high rate atrial signals. The microprocessor operates in conjunction with an atrial timer to detect atrial signals which occur at a rate in excess of a predefined atrial rate limit. The microprocessor paces the ventricle at a predefined desirable demand rate and inhibits pacing of the atrium in response to the high rate atrial activity. The microprocessor also controls the timing of an atrial refractory interval which includes an absolute refractory portion during which atrial signals are not detected and a relative refractory portion during which atrial signals are detected but are not tracked. The combined absolute and relative atrial refractory portions insure that relatively high rate atrial signals are detected and spurious signals conducted from the ventricle are ignored.
摘要翻译：可编程微处理器控制的双室心脏起搏器被编程为响应于高速率心房信号来控制心室起搏的时机。微处理器与心房定时器一起操作以检测以超过预定的心房率限制的速率发生的心房信号。微处理器以预定的期望需求速度使心室步行，并且响应于高速率心房活动而抑制心房起搏。微处理器还控制心房难治性时间间隔的时间，其包括不检测心房信号的绝对耐火部分和在其期间检测到但不被跟踪心房信号的相对耐火部分。组合的绝对和相对的心房难治部分确保检测到相对较高的率的心房信号，并且忽略从心室传导的杂散信号。

7. 发明申请

US20070067008A1 Leads for pacing and/or sensing the heart from within the coronary veins 审中-公开
标题翻译：引导在冠状静脉内起搏和/或感测心脏
公开(公告)号：US20070067008A1
公开(公告)日：2007-03-22
申请号：US11600807
申请日：2006-11-16
申请人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
发明人： Avram Scheiner , Ronald Heil , Peter Kelley , Bruce Tockman , Randy Westlund , Jay Warren
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead for monitoring or stimulating cardiac activity is provided. The lead is adapted for implantation on or about the heart within the coronary vasculature and for connection to a signal generator. The lead body has one or more electrodes associated therewith. The lead is constructed and arranged so that when it is implanted, the electrodes are housed in the coronary vasculature and urged into intimate contact a vessel wall.
摘要翻译：提供监测或刺激心脏活动的潜在客户。引线适于植入在冠状脉管系统内部或其周围的心脏上，并用于连接到信号发生器。引线体具有与其相关联的一个或多个电极。导线被构造和布置成使得当其被植入时，电极被容纳在冠状脉管系统中并被促使与血管壁紧密接触。

8. 发明申请

US20060116725A1 Method and apparatus for beat alignment and comparison 有权
标题翻译：拍子对准和比较的方法和装置
公开(公告)号：US20060116725A1
公开(公告)日：2006-06-01
申请号：US10999274
申请日：2004-11-29
申请人： Surekha Palreddy , Jay Warren , Alan Ostroff
发明人： Surekha Palreddy , Jay Warren , Alan Ostroff
IPC分类号： A61N1/39
CPC分类号： A61B5/04525 , A61B5/0464 , A61N1/3622 , A61N1/3956 , Y10S128/92
摘要： Methods of using a template having a template data set and template parameters to provide improved alignment of captured cardiac signal data to a stored template. More particularly, in an illustrative method, a captured cardiac signal is first configured using template parameters for a stored template. Then, once configured, the captured cardiac signal is then compared to the stored template. Other embodiments include implantable cardiac treatment devices including operational circuitry configured to perform the illustrative method. In a further embodiment, more than one stored templates may be used. Each template can have independently constructed templates, such that a single captured cardiac signal may be configured using first parameters for comparison to a first template, and using second parameters for comparison to a second template.
摘要翻译：使用具有模板数据集和模板参数的模板的方法来提供捕获的心脏信号数据与存储的模板的改进对准。更具体地，在说明性方法中，首先使用用于存储的模板的模板参数来配置捕获的心脏信号。然后，一旦配置，捕获的心脏信号然后与存储的模板进行比较。其他实施例包括可植入心脏治疗装置，其包括被配置为执行说明性方法的操作电路。在另一实施例中，可以使用多于一个的存储的模板。每个模板可以具有独立构造的模板，使得可以使用用于与第一模板进行比较的第一参数以及使用用于与第二模板进行比较的第二参数来配置单个捕获的心脏信号。

9. 发明申请

US20060089679A1 Method and apparatus for determining changes in heart failure status 有权
公开(公告)号：US20060089679A1
公开(公告)日：2006-04-27
申请号：US11299876
申请日：2005-12-12
申请人： Qingsheng Zhu , Julio Spinelli , Bruce KenKnight , Jay Warren
发明人： Qingsheng Zhu , Julio Spinelli , Bruce KenKnight , Jay Warren
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/36585
摘要： A method for operating a cardiac rhythm management device in which a clinical state vector is computed as a combination of a plurality of parameters related to a patient's heart failure status and compared to a previously computed clinical state vector to determine a clinical trajectory indicative of changes in the patient's heart failure status. Such detected changes in status can be used both as a clinical tool to evaluate treatment and to automatically adjust the operation of the device.

10. 发明申请

US20080015647A1 METHOD AND DEVICES FOR PERFORMING CARDIAC WAVEFORM APPRAISAL 有权
标题翻译：用于执行心脏波形评估的方法和设备
公开(公告)号：US20080015647A1
公开(公告)日：2008-01-17
申请号：US11781687
申请日：2007-07-23
申请人： Surekha Palreddy , Jay Warren , James Phillips
发明人： Surekha Palreddy , Jay Warren , James Phillips
IPC分类号： A61N1/39
CPC分类号： A61N1/365 , A61B5/0031 , A61B5/0422 , A61B5/04525 , A61B5/7207 , A61B5/7239 , A61N1/3622 , A61N1/368
摘要： Implementations of various technologies described herein are directed toward a sensing architecture for use in cardiac rhythm management devices. The sensing architecture may provide a method and means for certifying detected events by the cardiac rhythm management device. Moreover, by exploiting the enhanced capability to accurately identifying only those sensed events that are desirable, and preventing the use of events marked as suspect, the sensing architecture can better discriminate between rhythms appropriate for device therapy and those that are not.
摘要翻译：本文描述的各种技术的实现针对用于心律管理装置的感测架构。感测架构可以提供用于通过心律管理装置认证检测到的事件的方法和装置。此外，通过利用增强的能力来准确地仅识别那些感兴趣的事件，并且防止使用标记为可疑的事件，感测体系结构可以更好地区分适合于设备治疗的节律和不适合于设备治疗的节律。

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