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    • 1. 发明申请
    • SEPARATION METHOD USING SINGLE POLYMER PHASE SYSTEMS
    • 使用单个聚合物相系统的分离方法
    • US20120010390A1
    • 2012-01-12
    • US13143560
    • 2010-01-07
    • James Van AlstineJamil ShanagarRolf HjorthMartin HallCamilla Estmer Nilsson
    • James Van AlstineJamil ShanagarRolf HjorthMartin HallCamilla Estmer Nilsson
    • C07K16/00C07K1/36C07K14/00C07K1/14
    • C07K16/00C07K1/14C07K1/36C07K16/04C07K16/065C07K2317/10
    • The present invention relates to a process of enriching one target compound from a liquid, which process comprises at least one step of isolation performed by differentially partitioning between two aqueous phases. In the present invention the phases are formed by adding a thermally responsive, self-associating (i.e. clouding) hydrophilic polymer, and if needed some additional salts, to an aqueous biotechnical solution (such as a fermentation sample or bioseparation process stream) under thermal and other conditions where the solution separates into a one polymer, two-phase system with one phase enriched in the polymer. The target compound is to be found in the phase not enriched in the polymer, while a significant though varying percentage of contaminants may differentially partition to the phase interface or the polymer enriched phase. With minor or no modification the target containing phase solution can be further processed via standard unit operations such as precipitation, chromatography, and filtration to further purify target and remove any residual polymer.
    • 本发明涉及从液体中富集一种目标化合物的方法,该方法包括通过在两个水相之间进行差异分配而进行的至少一个分离步骤。 在本发明中,通过将热响应,自缔合(即,混浊)的亲水聚合物和如果需要的话添加一些额外的盐,在热和/或热处理下,向水生物技术溶液(例如发酵样品或生物分离工艺流) 溶液分离成一种聚合物的其它条件,两相体系中一相富集聚合物。 目标化合物可以在不富集聚合物的相中找到,而显着的不同百分比的污染物可以差异地分配到相界面或聚合物富集相。 通过微量或不改变,可以通过标准单元操作(如沉淀,色谱和过滤)进一步处理包含相溶液的溶液,以进一步纯化目标物并除去任何残留的聚合物。
    • 2. 发明授权
    • Separation method using single polymer phase systems
    • 使用单聚合物相系统的分离方法
    • US09115181B2
    • 2015-08-25
    • US13143560
    • 2010-01-07
    • James Van AlstineJamil ShanagarRolf HjorthMartin HallCamilla Estmer Nilsson
    • James Van AlstineJamil ShanagarRolf HjorthMartin HallCamilla Estmer Nilsson
    • A23J1/00C07K1/00C07K14/00C07K16/00C07K17/00C07K1/14C07K1/36C07K16/04C07K16/06
    • C07K16/00C07K1/14C07K1/36C07K16/04C07K16/065C07K2317/10
    • The present invention relates to a process of enriching one target compound from a liquid, which process comprises at least one step of isolation performed by differentially partitioning between two aqueous phases. In the present invention the phases are formed by adding a thermally responsive, self-associating (i.e. clouding) hydrophilic polymer, and if needed some additional salts, to an aqueous biotechnical solution (such as a fermentation sample or bioseparation process stream) under thermal and other conditions where the solution separates into a one polymer, two-phase system with one phase enriched in the polymer. The target compound is to be found in the phase not enriched in the polymer, while a significant though varying percentage of contaminants may differentially partition to the phase interface or the polymer enriched phase. With minor or no modification the target containing phase solution can be further processed via standard unit operations such as precipitation, chromatography, and filtration to further purify target and remove any residual polymer.
    • 本发明涉及从液体中富集一种目标化合物的方法,该方法包括通过在两个水相之间进行差异分配而进行的至少一个分离步骤。 在本发明中,通过将热响应,自缔合(即,混浊)的亲水聚合物和如果需要的话添加一些额外的盐,在热和/或热处理下,向水生物技术溶液(例如发酵样品或生物分离工艺流) 溶液分离成一种聚合物的其它条件,两相体系中一相富集聚合物。 目标化合物可以在不富集聚合物的相中找到,而显着的不同百分比的污染物可以差异地分配到相界面或聚合物富集相。 通过微量或不改变,可以通过标准单元操作(如沉淀,色谱和过滤)进一步处理包含相溶液的溶液,以进一步纯化目标物并除去任何残留的聚合物。
    • 3. 发明申请
    • Dual Laser Golf Training System
    • 双激光高尔夫训练系统
    • US20080305881A1
    • 2008-12-11
    • US11968823
    • 2008-01-03
    • Thomas PaulMartin Hall
    • Thomas PaulMartin Hall
    • A63B69/36
    • A63B69/3614A63B69/0057A63B69/3676A63B2071/0694
    • A golf training system and method wherein a device comprising a straight, elongated arm having an axis, a first proximal end, and a second distal end; a wrist bar connected to the elongated arm at a point near the first proximal end, extending perpendicularly from the straight, elongated arm at a right angle to the axis of the straight, elongated arm; a first green laser enclosed by the straight, elongated arm adapted to emit a green laser beam from the first proximal end along the axis; and a second green laser enclosed by the straight, elongated arm adapted to emit a green laser beam from the second distal end is used to train on plane swing, proper wrist angulations, proper hip turn, proper shoulder turn, and a proper putting motion.
    • 一种高尔夫训练系统和方法,其中包括具有轴线的直的细长臂的装置,第一近端和第二远端; 在靠近所述第一近端的点处连接到所述细长臂的腕条,所述手腕杆从所述直的细长臂垂直于所述直的细长臂的轴线垂直延伸; 由所述直的细长臂包围的第一绿色激光器,其适于沿着所述轴线从所述第一近端发射绿色激光束; 并且由适于从第二远端发射绿色激光束的直的细长臂包围的第二绿色激光器用于在平面摆动,适当的腕部角度,适当的髋关节转动,适当的肩部转动和适当的推进运动上训练。
    • 6. 发明授权
    • Delivering contextual advertising to a vehicle
    • 向车辆提供上下文广告
    • US08751293B2
    • 2014-06-10
    • US12466117
    • 2009-05-14
    • Martin HallAli KhanMark McNultyZhangwei Xu
    • Martin HallAli KhanMark McNultyZhangwei Xu
    • G06Q30/00G06Q90/00
    • G06Q90/00G06Q30/02G06Q30/0207G06Q30/0255G06Q30/0266
    • Systems and methods are provided for delivering contextual advertising to a vehicle. An example system may include a profiler module executed by an onboard computing device of the vehicle, and configured to aggregate vehicle event data from a plurality of vehicle-based event sources, and to develop user profile data based on the vehicle event data. A communication agent may also be executed by the onboard computing device, and configured to transmit the user profile data to an advertising service executed on an advertising server via a communication network. The communication agent may also be configured to retrieve an advertisement from the advertising service. The advertisement may be selected based on content of the user profile data. The system may also include an interface module executed by the onboard computing device, and configured to present the advertisement via a display, and/or speaker associated with the onboard computing device.
    • 系统和方法被提供用于向车辆传送上下文广告。 示例系统可以包括由车辆的车载计算设备执行并且被配置为从多个基于车辆的事件源聚合车辆事件数据并且基于车辆事件数据开发用户简档数据的轮廓仪模块。 通信代理还可以由板载计算设备执行,并且被配置为经由通信网络将用户简档数据发送到在广告服务器上执行的广告服务。 通信代理还可以被配置为从广告服务检索广告。 可以基于用户简档数据的内容来选择广告。 该系统还可以包括由机载计算设备执行的接口模块,并且被配置为经由与车载计算设备相关联的显示器和/或扬声器呈现广告。
    • 7. 发明授权
    • Chromatography method
    • 色谱法
    • US07901581B2
    • 2011-03-08
    • US12602774
    • 2008-06-12
    • Mattias BryntessonMartin HallKarol Lacki
    • Mattias BryntessonMartin HallKarol Lacki
    • B01D15/08
    • B01D15/1828B01D15/1864B01D15/203G01N30/02G01N30/461G01N30/467G01N30/468G01N30/88G01N2030/8827G01N2030/8831G01N2030/8886B01D15/1821
    • The present invention relates to a simulated moving bed process, wherein at least one adsorbent is washed after binding of target compound and wherein the outlet of wash liquid from the adsorbent is subsequently passed onto another adsorbent for binding of target compound removed by the washing. In one embodiment, the method comprises binding of at least one target compound using three or more adsorbents connected in series and elution of target compound from said three adsorbents. After the binding to an adsorbent, wash liquid is passed across the adsorbent to recover desorbed and/or unbound target compound, and the outlet of such wash liquid is directed to the adsorbent after the next in the series, to which no feed has yet been added. The target compound is recovered by eluting target compound from the washed adsorbents.
    • 本发明涉及一种模拟移动床方法,其中在目标化合物结合之后洗涤至少一种吸附剂,其中来自吸附剂的洗涤液的出口随后通过另一种吸附剂,用于通过洗涤除去的目标化合物的结合。 在一个实施方案中,该方法包括使用三个或更多个串联连接的吸附剂和从所述三个吸附剂中洗脱目标化合物来结合至少一种目标化合物。 在结合到吸附剂之后,洗涤液体通过吸附剂以回收解吸和/或未结合的目标化合物,并且这种洗涤液体的出口在序列中的下一个之后被引导到吸附剂,其中还没有进料 添加。 通过从洗涤的吸附剂洗脱目标化合物来回收目标化合物。
    • 9. 发明申请
    • CHROMATOGRAPHY METHOD
    • 色谱法
    • US20100176058A1
    • 2010-07-15
    • US12602774
    • 2008-06-12
    • Mattias BryntessonMartin HallKarol Lacki
    • Mattias BryntessonMartin HallKarol Lacki
    • B01D15/14B01D15/08
    • B01D15/1828B01D15/1864B01D15/203G01N30/02G01N30/461G01N30/467G01N30/468G01N30/88G01N2030/8827G01N2030/8831G01N2030/8886B01D15/1821
    • The present invention relates to a simulated moving bed process, wherein at least one adsorbent is washed after binding of target compound and wherein the outlet of wash liquid from the adsorbent is subsequently passed onto another adsorbent for binding of target compound removed by the washing. In one embodiment, the method comprises binding of at least one target compound using three or more adsorbents connected in series and elution of target compound from said three adsorbents. After the binding to an adsorbent, wash liquid is passed across the adsorbent to recover desorbed and/or unbound target compound, and the outlet of such wash liquid is directed to the adsorbent after the next in the series, to which no feed has yet been added. The target compound is recovered by eluting target compound from the washed adsorbents.
    • 本发明涉及一种模拟移动床方法,其中在目标化合物结合之后洗涤至少一种吸附剂,其中来自吸附剂的洗涤液的出口随后通过另一种吸附剂,用于通过洗涤除去的目标化合物的结合。 在一个实施方案中,该方法包括使用三个或更多个串联连接的吸附剂和从所述三个吸附剂中洗脱目标化合物来结合至少一种目标化合物。 在结合到吸附剂之后,洗涤液体通过吸附剂以回收解吸和/或未结合的目标化合物,并且这种洗涤液体的出口在序列中的下一个之后被引导到吸附剂,其中还没有进料 添加。 通过从洗涤的吸附剂洗脱目标化合物来回收目标化合物。