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1. 发明授权

US5504326A Spatial-velocity correlation focusing in time-of-flight mass spectrometry 失效
标题翻译：飞行时间质谱中的空间 - 速度相关性
公开(公告)号：US5504326A
公开(公告)日：1996-04-02
申请号：US327618
申请日：1994-10-24
申请人： James P. Reilly , Steven M. Colby , Timothy B. King
发明人： James P. Reilly , Steven M. Colby , Timothy B. King
IPC分类号： H01J49/40
CPC分类号： H01J49/0031 , H01J49/40
摘要： An apparatus and method for minimizing ion peak width measurements in a time-of-flight mass spectrometer to thereby minimize the effects of initial ion position distributions and initial ion velocity distributions on the mass resolution of the spectrometer are provided. Where the ion source and ion generation geometries indicate a functional relationship between the initial ion position and initial ion velocity, this relationship is substituted into the time-of-flight equation and the instrument parameters are thereafter optimized to achieve minimization of ion peak width broadening. Experimental results using MALDI indicate reductions in ion peak widths of up to 96% over those observed with traditional MALDI techniques.
摘要翻译：提供了一种用于使飞行时间质谱仪中的离子峰宽度测量最小化从而最小化初始离子位置分布和初始离子速度分布对光谱仪质量分辨率的影响的装置和方法。当离子源和离子生成几何形状表示初始离子位置和初始离子速度之间的函数关系时，将该关系替换为飞行时间方程式，然后对仪器参数进行优化，以实现离子峰值宽度加宽的最小化。使用MALDI的实验结果表明，离子峰宽度比传统MALDI技术观察到的降低高达96％。

2. 发明授权

US5712479A Spatial-velocity correlation focusing in time-of-flight mass spectrometry 失效
公开(公告)号：US5712479A
公开(公告)日：1998-01-27
申请号：US566140
申请日：1995-12-01
申请人： James P. Reilly , Steven M. Colby , Timothy B. King
发明人： James P. Reilly , Steven M. Colby , Timothy B. King
IPC分类号： H01J49/40
CPC分类号： H01J49/0031 , H01J49/40
摘要： An apparatus and method for minimizing ion peak width measurements in a time-of-flight mass spectrometer to thereby minimize the effects of initial ion position distributions and initial ion velocity distributions on the mass resolution of the spectrometer are provided. Where the ion source and ion generation geometries indicate a functional relationship between the initial ion position and initial ion velocity, this relationship is substituted into the time-of-flight equation and the instrument parameters are thereafter optimized to achieve minimization of ion peak width broadening. Experimental results using MALDI indicate reductions in ion peak widths of up to 96% over those observed with traditional MALDI techniques.

3. 发明授权

US5510613A Spatial-velocity correlation focusing in time-of-flight mass spectrometry 失效
公开(公告)号：US5510613A
公开(公告)日：1996-04-23
申请号：US477198
申请日：1995-06-07
申请人： James P. Reilly , Steven M. Colby , Timothy B. King
发明人： James P. Reilly , Steven M. Colby , Timothy B. King
IPC分类号： H01J49/40
CPC分类号： H01J49/0031 , H01J49/40
摘要： An apparatus and method for minimizing ion peak width measurements in a time-of-flight mass spectrometer to thereby minimize the effects of initial ion position distributions and initial ion velocity distributions on the mass resolution of the spectrometer are provided. Where the ion source and ion generation geometries indicate a functional relationship between the initial ion position and initial ion velocity, this relationship is substituted into the time-of-flight equation and the instrument parameters are thereafter optimized to achieve minimization of ion peak width broadening. Experimental results using MALDI indicate reductions in ion peak widths of up to 96% over those observed with traditional MALDI techniques.

4. 发明授权

US5740549A Information and advertising distribution system and method 失效
标题翻译：信息和广告分发系统及方法
公开(公告)号：US5740549A
公开(公告)日：1998-04-14
申请号：US489591
申请日：1995-06-12
申请人： James P. Reilly , Gregory P. Hassett
发明人： James P. Reilly , Gregory P. Hassett
IPC分类号： G06F13/00 , G06F3/048 , G06F3/14 , G06F17/30 , G06Q30/02 , G06Q30/06 , G09F27/00 , H04L12/18 , H04N21/442 , H04N21/81 , G06F17/60
CPC分类号： H04N21/44222 , G06Q30/0243 , G06Q30/0257 , G06Q30/0272 , G06Q30/0277 , G06Q30/0601 , G09F27/00 , H04N21/812 , G09G2330/04
摘要： In summary, the present invention is an information and advertising distribution system. A data server stores and updates a database of information items and advertisements. The information items and advertisements are each categorized so that each has an associated information category. Workstations remotely located from the data server each include a display device, a communication interface for receiving at least a subset of the information items and advertisements in the data server's database and local memory for storing the information items and advertisements received from the data server. An information administrator in each workstation establishes communication with the data server from time to time so as to update the information items and advertisements stored in local memory with at least a subset of the information items and advertisements stored by the data server. An information display controller in each workstation displays on the workstation's display device at least a subset of the information items and advertisements stored in local memory when the workstation meets predefined idleness criteria. At least a subset of the workstations include a profiler for storing subscriber profile data. The subscriber profile data represents subscriber information viewing preferences, indicating information categories for which the subscriber does and does not want to view information items. The information display controller includes a filter for excluding from the information items displayed on the display device those information items inconsistent with the subscriber profile data.
摘要翻译：总之，本发明是一种信息和广告分发系统。数据服务器存储和更新信息项和广告的数据库。信息项目和广告被分类，使得每个信息项目和广告都具有关联的信息类别。远程位于数据服务器的工作站各自包括显示设备，用于接收数据服务器数据库中的信息项和广告的至少一个子集的通信接口以及用于存储从数据服务器接收的信息项和广告的本地存储器。每个工作站中的信息管理员不时地建立与数据服务器的通信，以便利用数据服务器存储的信息项和广告的至少一个子集来更新存储在本地存储器中的信息项和广告。当工作站满足预定义的闲置标准时，每个工作站中的信息显示控制器在工作站的显示设备上显示存储在本地存储器中的信息项和广告的至少一个子集。工作站的至少一个子集包括用于存储用户简档数据的分析器。订户简档数据表示用户信息查看偏好，指示用户所为并且不想查看信息项的信息类别。信息显示控制器包括用于从显示设备上显示的信息项排除与用户简档数据不一致的信息项的过滤器。

5. 发明授权

US4635269A Flowing gas laser having screening for smoothing low turbulence flow 失效
标题翻译：流动气体激光器具有平滑低湍流流量的筛选
公开(公告)号：US4635269A
公开(公告)日：1987-01-06
申请号：US699672
申请日：1985-02-08
申请人： James P. Reilly , M. John Yoder
发明人： James P. Reilly , M. John Yoder
IPC分类号： H01S3/097 , H01S3/03 , H01S3/036 , H01S3/22
CPC分类号： H01S3/036
摘要： A flowing gas laser of the kind normally operating in the glow discharge mode and having a glow discharge region through which the gas flows while the glow discharge occurs, employs one or an array of flow smoothing screens disposed in series in the gas flow path in a manner that enables the input power loading to be increased without causing arcing in the electric discharge of the lasing gas. The screens are disposed upstream of the glow discharge region and cause smoothing of small scale turbulence in the gas flow. The screen closest to the discharge region is spaced from the beginning of that region by a distance not less than ten times the distance between adjacent holes of the screen. Successive screens in the series array are spaced at intervals sufficient to enable the requisite flow smoothing by each screen to occur before the flow encounters the next screen of the array.
摘要翻译：通常在辉光放电模式下工作并具有辉光放电区域的流动气体激光器，其中在辉光放电发生时气体流过的辉光放电区域采用在气体流路中串联布置的一个或一组流动平滑屏幕使得能够增加输入功率负载而不引起激光气体的放电中的电弧。屏幕设置在辉光放电区域的上游，并导致气流中的小规模湍流的平滑化。最靠近放电区域的屏幕与该区域的开始间隔不小于屏幕相邻孔之间距离的十倍。串联阵列中的连续屏幕间隔足够的间隔，以便在流程遇到阵列的下一个屏幕之前使每个屏幕能够平滑所需的流程平滑。

6. 发明授权

US4344040A Method and apparatus for providing the in-phase and quadrature components of a bandpass signal 失效
标题翻译：提供带通信号的同相和正交分量的方法和装置
公开(公告)号：US4344040A
公开(公告)日：1982-08-10
申请号：US133911
申请日：1980-03-26
申请人： James P. Reilly , Simon Haykin
发明人： James P. Reilly , Simon Haykin
IPC分类号： H03D1/22 , H03D3/18
CPC分类号： H03D1/2245
摘要： The method and apparatus provides the in-phase I and quadrature Q components of a bandpass signal x(t) of center frequency f.sub.c and bandwidth 2w. The signal x(t) is heterodyned to have an intermediate center frequency f.sub.o where w.ltoreq.f.sub.o .ltoreq.f.sub.c. This signal is divided into two signals and each is sampled during successive periods T.sub.s where T.sub.s =m/f.sub.o and m is an integer. However, the instant of sampling of one signal is shifted with respect to the other by b/4f.sub.o where b is an odd integer. In the various implementations, the shift may be either positive, negative, or both, to provide the quadrature component Q, whereas the sampling of the other signal provides the in-phase component I.
摘要翻译：该方法和装置提供中心频率fc和带宽2w的带通信号x（t）的同相I和正交Q分量。信号x（t）被外差以具有中间中心频率fo，其中w

7. 发明授权

US09828267B1 MBR frame 有权
公开(公告)号：US09828267B1
公开(公告)日：2017-11-28
申请号：US13605374
申请日：2012-09-06
申请人： James P. Reilly , Victoria Jelderks
发明人： James P. Reilly , Victoria Jelderks
IPC分类号： C02F3/00 , C02F3/12
CPC分类号： C02F3/00 , B01D17/12 , B01D21/30 , B01D35/00 , B01D35/14 , C02F3/006 , C02F3/04 , C02F3/06 , C02F3/082 , C02F3/1268 , C02F3/1273 , C02F3/14 , C02F3/302 , C02F2203/006 , C02F2209/005 , C02F2209/40 , Y02W10/15
摘要： Embodiments described methods, systems and apparatuses to utilize a plurality of membrane cartridges and a housing frame comprising a lightweight corrosion resistant material (e.g., non-corrosive metals, non-corrosive composites such as PVC, HDPE and FRP). The anti-corrosive properties of said frame allow of it to be re-used (e.g., with replaced MBR filters). Said MBR frame may be used in a single function or multi-function wastewater treatment container. Said container may also include a corrosion resistant liner coupled to interior portions of each of the base and side walls of the basin, an inlet to receive wastewater treatment influent into the basin, and an outlet to output wastewater treatment process material from the basin.

8. 发明授权

US09669330B1 WWTP sensor cartridge 有权
公开(公告)号：US09669330B1
公开(公告)日：2017-06-06
申请号：US13605365
申请日：2012-09-06
申请人： James P. Reilly , Victoria Jelderks
发明人： James P. Reilly , Victoria Jelderks
IPC分类号： B01D21/24 , B01D21/30 , G01N11/00 , B01D17/12 , B01D35/00 , B01D35/14
CPC分类号： C02F3/00 , B01D17/12 , B01D21/30 , B01D35/00 , B01D35/14 , C02F3/006 , C02F3/04 , C02F3/06 , C02F3/082 , C02F3/1268 , C02F3/1273 , C02F3/14 , C02F3/302 , C02F2203/006 , C02F2209/005 , C02F2209/40 , Y02W10/15
摘要： Embodiments describe apparatuses, systems and methods for utilizing a configurable WWTP container having a removable sensor/controller cartridge. Said removable cartridge is configured for collecting and analyzing data for any given configuration of a WWTP container, and is positioned securely separate from the treatment compartment(s) of the WWTP container. The removable cartridge is able to monitor operation conditions of the wastewater treatment compartment(s) via control logic and at least one sensor included in the removable cartridge, and change operating parameters of the container.

9. 发明授权

US06323482B1 Ion mobility and mass spectrometer 有权
标题翻译：离子迁移率和质谱仪
公开(公告)号：US06323482B1
公开(公告)日：2001-11-27
申请号：US09313492
申请日：1999-05-17
申请人： David E. Clemmer , James P. Reilly
发明人： David E. Clemmer , James P. Reilly
IPC分类号： H01J4940
CPC分类号： G01N27/622 , H01J49/004 , H01J49/40 , H01J49/42
摘要： An ion mobility and mass spectrometer instrument includes an ion source region coupled to an ion mobility spectrometer having an ion outlet coupled to a quadrupole mass filter. An output of the filter is coupled to a collision cell which has an ion outlet coupled to an ion acceleration region of a mass spectrometer such as a time of flight mass spectrometer. The instrument is particularly well suited for sequencing analysis wherein a sample is ionized and a resulting three-dimensional ion spectrum (ion intensity vs. ion mobility and ion mass) is observed. If the spectrum reveals that no ions overlap in mobility values, the collision cell is filled with a suitable buffer gas and the instrument is reactivated whereby a complete three-dimensional spectrum of parent and daughter ions results. If, however, the original spectrum reveals that two or more ions overlap in ion mobility values, the collision cell is filled with a buffer gas and the quadrupole mass filter is controlled to selectively filter out all but one of the ions having overlapping mobility values. The instrument is reactivated, and the quadrupole mass filter is selectively controlled, as many times as mobility overlap occurs to thereby provide complete three-dimensional spectra of parent and daughter ions resulting from fragmentation. Various configurations of mass filter, ion trap and collision cell positioning, relative to the ion mobility and mass spectrometer instruments, are contemplated.
摘要翻译：离子迁移率和质谱仪器包括耦合到具有耦合到四极质量过滤器的离子出口的离子迁移谱仪的离子源区域。滤波器的输出耦合到具有耦合到诸如飞行时间质谱仪的质谱仪的离子加速度区域的离子出口的碰撞池。该仪器特别适用于样品离子化的测序分析，并且观察到所得的三维离子光谱（离子强度对离子迁移率和离子质量）。如果光谱显示没有离子在迁移率值上重叠，则碰撞池填充有合适的缓冲气体，并且仪器被再活化，由此产生完整的母体和子离子的三维光谱。然而，如果原始光谱显示两个或更多个离子在离子迁移率值中重叠，则碰撞单元填充有缓冲气体，并且控制四极质量过滤器以选择性地过滤掉具有重叠迁移率值的所有离子之外的所有离子。仪器被重新激活，并且四极质量过滤器被选择性地控制，发生迁移重叠的次数多，从而提供由碎裂产生的母体和子体离子的完整的三维光谱。考虑到相对于离子迁移率和质谱仪器的质量过滤器，离子阱和碰撞池定位的各种配置。

10. 发明授权

US06956422B2 Generation and measurement of timing delays by digital phase error compensation 失效
标题翻译：通过数字相位误差补偿生成和测量定时延迟
公开(公告)号：US06956422B2
公开(公告)日：2005-10-18
申请号：US10744834
申请日：2003-12-23
申请人： James P. Reilly , Noah P. Christian
发明人： James P. Reilly , Noah P. Christian
IPC分类号： G01R31/30 , G01R31/317 , G01R31/3193 , H03H11/26
CPC分类号： G01R31/31725 , G01R31/3016 , G01R31/31937
摘要： A circuit and method for generating a delayed event following a trigger pulse occurring at a random time between clock pulses is disclosed. The circuit includes a clock circuit, a voltage converter, an analog-to-digital converter circuit, a memory storage circuit, and a summing circuit. The method includes representing the time between the triggering pulse and a subsequent clock pulse as a voltage, converting the voltage to a stored digital value, and defining a desired delay time by adding a first time determined by counting a predetermined number of clock cycles to a second time determined by converting the stored digital value first to an analog value and then to a time value.
摘要翻译：公开了用于在时钟脉冲之后的随机时间发生的触发脉冲之后产生延迟事件的电路和方法。电路包括时钟电路，电压转换器，模数转换器电路，存储器存储电路和求和电路。该方法包括将触发脉冲和随后的时钟脉冲之间的时间表示为电压，将电压转换为存储的数字值，并通过将通过计数预定数量的时钟周期确定的第一时间添加到通过将所存储的数字值首先转换为模拟值然后再转换为时间值来确定第二次。

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