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1. 发明授权

US08303821B2 Reduction of antimicrobial compound levels during product dispensing 有权
标题翻译：降低产品分配过程中的抗菌化合物含量
公开(公告)号：US08303821B2
公开(公告)日：2012-11-06
申请号：US12763692
申请日：2010-04-20
申请人： Ioana Annis , Perrine Brel , Jean Ferraro , Thierry Lacour , Richard Levy , Yves Louis Walter C. Vandenberghe
发明人： Ioana Annis , Perrine Brel , Jean Ferraro , Thierry Lacour , Richard Levy , Yves Louis Walter C. Vandenberghe
IPC分类号： B01D15/04
CPC分类号： A61Q17/005 , A61K8/8117 , A61K8/8147 , A61K2800/524 , A61K2800/54
摘要： A method for reducing antimicrobial compound levels in a liquid composition containing at least one antimicrobial compound. The method comprises contacting said liquid composition with a functionalized resin. Antimicrobial compounds that may be removed by this method include isothiazolin-3-ones, e.g., 2-methyl-4-isothiazolin-3-one; 5-chloro-2-methyl-4-isothiazolin-3-one; 2-n-octyl-4-isothiazolin-3-one; 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one; 1,2-benzisothiazolin-3-one and N-alkyl derivatives thereof, especially N-methyl and N-n-butyl; 2,2-dibromo-3-nitrilopropionamide (DBNPA); 2-bromo-2-nitropropanediol (BNPD); dithio-2,2′-bis(benzmethylamide) (DTBMA); hexetidine; chlorphenesin, C1-C4 alkyl-4-hydroxybenzoates (alkyl parabens); 3-iodopropynylbutylcarbamate (IPBC); formaldehyde releasers and mixtures thereof.
摘要翻译：一种降低含有至少一种抗微生物化合物的液体组合物中的抗微生物化合物含量的方法该方法包括使所述液体组合物与官能化树脂接触。可以通过该方法除去的抗微生物化合物包括异噻唑啉-3-酮，例如2-甲基-4-异噻唑啉-3-酮; 5-氯-2-甲基-4-异噻唑啉-3-酮; 2-正辛基-4-异噻唑啉-3-酮; 4,5-二氯-2-正辛基-4-异噻唑啉-3-酮; 1,2-苯并异噻唑啉-3-酮及其N-烷基衍生物，特别是N-甲基和N-正丁基; 2,2-二溴-3-硝基丙酰胺（DBNPA）; 2-溴-2-硝基丙二醇（BNPD）; 二苯基-2,2'-双（苯甲酰胺）（DTBMA）; 己氮啶氯苯辛素，C 1 -C 4烷基-4-羟基苯甲酸酯（对羟基苯甲酸烷基酯）; 3-碘丙炔基丁基氨基甲酸酯（IPBC）; 甲醛释放剂及其混合物。

2. 发明申请

US20100270241A1 REDUCTION OF ANTIMICROBIAL COMPOUND LEVELS DURING PRODUCT DISPENSING 有权
标题翻译：在产品分配期间减少抗微生物化合物水平
公开(公告)号：US20100270241A1
公开(公告)日：2010-10-28
申请号：US12763692
申请日：2010-04-20
申请人： Ioana Annis , Perrine Brel , Jean Ferraro , Thierry Lacour , Richard Levy , Yves Louis Walter C. Vandenberghe
发明人： Ioana Annis , Perrine Brel , Jean Ferraro , Thierry Lacour , Richard Levy , Yves Louis Walter C. Vandenberghe
IPC分类号： B01D15/04
CPC分类号： A61Q17/005 , A61K8/8117 , A61K8/8147 , A61K2800/524 , A61K2800/54
摘要： A method for reducing antimicrobial compound levels in a liquid composition containing at least one antimicrobial compound. The method comprises contacting said liquid composition with a functionalized resin. Antimicrobial compounds that may be removed by this method include isothiazolin-3-ones, e.g., 2-methyl-4-isothiazolin-3-one; 5-chloro-2-methyl-4-isothiazolin-3-one; 2-n-octyl-4-isothiazolin-3-one; 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one; 1,2-benzisothiazolin-3-one and N-alkyl derivatives thereof, especially N-methyl and N-n-butyl; 2,2-dibromo-3-nitrilopropionamide (DBNPA); 2-bromo-2-nitropropanediol (BNPD); dithio-2,2′-bis(benzmethylamide) (DTBMA); hexetidine; chlorphenesin, C1-C4 alkyl-4-hydroxybenzoates (alkyl parabens); 3-iodopropynylbutylcarbamate (IPBC); formaldehyde releasers and mixtures thereof.
摘要翻译：一种降低含有至少一种抗微生物化合物的液体组合物中的抗微生物化合物含量的方法。该方法包括使所述液体组合物与官能化树脂接触。可以通过该方法除去的抗微生物化合物包括异噻唑啉-3-酮，例如2-甲基-4-异噻唑啉-3-酮; 5-氯-2-甲基-4-异噻唑啉-3-酮; 2-正辛基-4-异噻唑啉-3-酮; 4,5-二氯-2-正辛基-4-异噻唑啉-3-酮; 1,2-苯并异噻唑啉-3-酮及其N-烷基衍生物，特别是N-甲基和N-正丁基; 2,2-二溴-3-硝基丙酰胺（DBNPA）; 2-溴-2-硝基丙二醇（BNPD）; 二苯基-2,2'-双（苯甲酰胺）（DTBMA）; 己氮啶氯苯衍生物，C 1 -C 4烷基-4-羟基苯甲酸酯（对羟基苯甲酸烷基酯）; 3-碘代丙炔基丁基氨基甲酸酯（IPBC）; 甲醛释放剂及其混合物。

3. 发明申请

US20120172403A1 LOW TEMPERATURE STABLE SOLUTION 审中-公开
标题翻译：低温稳定的解决方案
公开(公告)号：US20120172403A1
公开(公告)日：2012-07-05
申请号：US13326833
申请日：2011-12-15
申请人： Thomas Koehler , Richard Levy , Roger G. Hamel
发明人： Thomas Koehler , Richard Levy , Roger G. Hamel
IPC分类号： A01N43/80 , A01P1/00
CPC分类号： A01N43/80 , C08K5/10 , C08K5/46 , A01N2300/00 , A01N25/02
摘要： This invention relates to liquid concentrates of 4,5-dichloro-2-(n-octyl-4-isothiazolin-3-one) (“DCOIT”) which are stable to crystallization or freezing at sub-freezing temperatures.
摘要翻译：本发明涉及在亚冰点温度下结晶稳定或冷冻的4,5-二氯-2-（正辛基-4-异噻唑啉-3-酮）（“DCOIT”）的液体浓缩物。

4. 发明申请

US20070078118A1 Microbicidal composition 有权
标题翻译：杀菌组合物
公开(公告)号：US20070078118A1
公开(公告)日：2007-04-05
申请号：US11529199
申请日：2006-09-28
申请人： Richard Levy , Megan Diehl , Dolores Shaw , Eileen Warwick
发明人： Richard Levy , Megan Diehl , Dolores Shaw , Eileen Warwick
IPC分类号： A01N43/80 , A01N43/50 , A01N55/02 , A01N33/12 , A01N37/44
CPC分类号： A61K31/428 , A01N43/80 , A01N2300/00 , A61K2300/00 , Y02A50/473 , A01N31/02 , A01N31/04 , A01N31/14 , A01N33/12 , A01N35/08 , A01N37/06 , A01N37/10 , A01N37/12 , A01N37/36 , A01N37/40 , A01N37/44 , A01N41/04 , A01N41/12 , A01N43/16 , A01N43/50 , A01N43/54 , A01N43/90 , A01N55/02 , A01N57/12
摘要： Synergistic microbicidal compositions containing N-(n-butyl)-1,2-benzisothiazolin-3-one or N-methyl-1,2-benzisothiazolin-3-one.
摘要翻译：含有N-（正丁基）-1,2-苯并异噻唑啉-3-酮或N-甲基-1,2-苯并异噻唑啉-3-酮的协同杀菌组合物。

5. 发明申请

US20060106024A1 Microbicidal composition 有权
标题翻译：杀菌组合物
公开(公告)号：US20060106024A1
公开(公告)日：2006-05-18
申请号：US11265654
申请日：2005-11-02
申请人： Richard Levy , Megan Diehl , Dolores Shaw , Eileen Warwick
发明人： Richard Levy , Megan Diehl , Dolores Shaw , Eileen Warwick
IPC分类号： A61K31/425 , A61K31/498 , C09D5/16 , A61K31/50
CPC分类号： C09D5/1625 , A01N43/80 , A61K31/425 , A61K31/498 , A61K31/50 , A01N57/12 , A01N55/02 , A01N43/90 , A01N43/54 , A01N43/50 , A01N43/40 , A01N43/08 , A01N37/52 , A01N37/44 , A01N37/40 , A01N37/10 , A01N33/12 , A01N31/14 , A01N37/16 , A01N47/36 , A01N31/02 , A01N31/04 , A01N2300/00
摘要： A microbicidal composition containing: (a) 1,2-benzisothiazolin-3-one; and (b) at least one microbicide selected from among benzalkonium chloride, benzethonium chloride, benzyl alcohol, caprylyl glycol, chlorphenesin, 2,2′-dithiobis(N-methylbenzamide), diazolidinyl urea, ethylenediamine tetraacetic acid, ethylparaben, imidazolidinyl urea, methylparaben, phenoxyethanol, linoleamidopropyl PG-dimonium chloride phosphate, cocamidopropyl PG-dimonium chloride phosphate, propylparaben, cis-1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride, dehydroacetic acid or its salts, benzoic acid or its salts, sodium hydroxymethylglycinate and zinc pyrithione.
摘要翻译：一种杀微生物组合物，其含有：（a）1,2-苯并异噻唑啉-3-酮; 和（b）至少一种选自苯扎氯铵，苄索氯铵，苄醇，辛酰基二醇，氯苯林宁，2,2'-二硫代双（N-甲基苯甲酰胺），重氮烷基脲，乙二胺四乙酸，对羟基苯甲酸乙酯，咪唑烷基脲，对羟基苯甲酸甲酯，苯氧基乙醇，亚油酰氨基丙基PG-二甲基氯化铵磷酸酯，椰油酰氨基丙基PG-二甲基氯化铵磷酸盐，对羟基苯甲酸丙酯，顺式-1-（3-氯烯丙基）-3,5,7-三氮杂-1-氮鎓金刚烷氯化物，脱氢乙酸或其盐，苯甲酸或其盐，羟基甲基甘氨酸钠和吡啶硫酮锌。

6. 发明授权

US06387386B1 Controlled delivery compositions and processes for treating organisms in a column of water or on land 失效
公开(公告)号：US06387386B1
公开(公告)日：2002-05-14
申请号：US09457888
申请日：1999-12-10
申请人： Richard Levy
发明人： Richard Levy
IPC分类号： A01N2510
CPC分类号： A01N49/00 , A01N25/10 , A01N25/26 , A01N25/34 , A01N43/90 , A01N57/14 , A01N63/00 , Y10S206/811 , Y10S424/08 , Y10S424/09 , Y10S424/10 , Y10S424/11 , Y10S514/918 , Y10S514/919 , Y10S514/92 , Y10T428/13 , Y10T428/1307 , Y10T428/1348 , Y10T428/1352 , Y10T428/139 , A01N2300/00
摘要： Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms. Methods for treating a column of water are also disclosed which comprises delivering the compositions to a column of water or to a dry preflood area (pretreatment) that will develop in a column of water or a flood area. The composition and process can also be used to treat terrestrial organisms.

7. 发明授权

US06337078B1 Controlled delivery compositions and processes for treating organisms in a column of water or land 失效
标题翻译：用于处理水或土地柱中生物体的受控输送组合物和方法
公开(公告)号：US06337078B1
公开(公告)日：2002-01-08
申请号：US09458023
申请日：1999-12-10
申请人： Richard Levy
发明人： Richard Levy
IPC分类号： A01N2532
CPC分类号： A01N49/00 , A01N25/10 , A01N25/26 , A01N25/34 , A01N43/90 , A01N57/14 , A01N63/00 , Y10S206/811 , Y10S424/08 , Y10S424/09 , Y10S424/10 , Y10S424/11 , Y10S514/918 , Y10S514/919 , Y10S514/92 , Y10T428/13 , Y10T428/1307 , Y10T428/1348 , Y10T428/1352 , Y10T428/139 , A01N2300/00
摘要： Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms. Methods for treating a column of water are also disclosed which comprises delivering the compositions to a column of water or to a dry preflood area (pretreatment) that will develop in a column of water or a flood area. The composition and process can also be used to treat terrestrial organisms.
摘要翻译：公开了物质的控制释放组合物，其包含用于处理水柱中的一种或多种水生生物群体的复合物。所述复合物包含至少一种系统，其中所述系统包含至少一种生物活性剂作为选择用于治疗水生生物群体的至少一种生物活性剂，至少一种载体组分和用于调节受控释放速率和释放曲线的至少一种包衣组分水中的生物活性剂或至少一种生物活性剂和一种共同功能组分，其可以用作载体和涂层，以调节生物活性剂在水中的控制释放速率和释放曲线，具有或不具有任选的粘合剂组分和/ 或其他制剂材料。选择组分沉降或漂浮，使得复合物将渗透和/或保留在水柱的任何平面或体积段中足以有效治疗水生生物体的一段时间。还公开了处理水柱的方法，其包括将组合物输送到一列水或将在一列水或洪水区域中形成的干燥预混区域（预处理）。组合物和方法也可用于处理陆生生物。

8. 发明授权

US06335027B1 Controlled delivery compositions and processes for treating organisms in a column of water or land 失效
公开(公告)号：US06335027B1
公开(公告)日：2002-01-01
申请号：US09458045
申请日：1999-12-10
申请人： Richard Levy
发明人： Richard Levy
IPC分类号： A01N2534
CPC分类号： A01N49/00 , A01N25/10 , A01N25/26 , A01N25/34 , A01N43/90 , A01N57/14 , A01N63/00 , Y10S206/811 , Y10S424/08 , Y10S424/09 , Y10S424/10 , Y10S424/11 , Y10S514/918 , Y10S514/919 , Y10S514/92 , Y10T428/13 , Y10T428/1307 , Y10T428/1348 , Y10T428/1352 , Y10T428/139 , A01N2300/00
摘要： Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms. Methods for treating a column of water are also disclosed which comprises delivering the compositions to a column of water or to a dry preflood area (pretreatment) that will develop in a column of water or a flood area. The composition and process can also be used to treat terrestrial organisms.

9. 发明授权

US6001382A Controlled delivery compositions and processes for treating organisms in a column of water or on land 失效
标题翻译：用于处理水或陆地上的生物体的受控递送组合物和方法
公开(公告)号：US6001382A
公开(公告)日：1999-12-14
申请号：US674813
申请日：1996-07-03
申请人： Richard Levy
发明人： Richard Levy
IPC分类号： A01N25/08 , A01N25/10 , A01N25/26 , A01N25/28 , A01N25/34 , A01N43/90 , A01N49/00 , A01N57/14 , A01N63/00
CPC分类号： A01N49/00 , A01N25/10 , A01N25/26 , A01N25/34 , A01N43/90 , A01N57/14 , A01N63/00 , Y10S206/811 , Y10S424/08 , Y10S424/09 , Y10S424/10 , Y10S424/11 , Y10S514/918 , Y10S514/919 , Y10S514/92 , Y10T428/13 , Y10T428/1307 , Y10T428/1348 , Y10T428/1352 , Y10T428/139
摘要： Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one high molecular weight organic plasticizer coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms. Methods for treating a column of water are also disclosed which comprises delivering the compositions to a column of water or to a dry preflood area (pretreatment) that will develop in a column of water or a flood area. The composition and process can also be used to treat terrestrial organisms in surface and subsurface areas fof a land mass.
摘要翻译：公开了物质的控制释放组合物，其包含用于处理水柱中的一种或多种水生生物群体的复合物。所述复合物包含至少一种系统，其中所述系统包含至少一种生物活性剂作为选择用于治疗水生生物群体的至少一种生物活性剂，至少一种载体组分和用于调节受控释放的至少一种高分子量有机增塑剂涂料组分生物活性剂在水中的速率和释放曲线或至少一种生物活性剂和一种联合功能组分，其可以用作载体和涂层以调节生物活性剂在水中的受控释放速率和释放曲线，有或没有可选的粘合剂组分和/或其它制剂材料。选择组分沉降或漂浮，使得复合物将渗透和/或保留在水柱的任何平面或体积段中足以有效治疗水生生物体的一段时间。还公开了处理水柱的方法，其包括将组合物输送到一列水或将在一列水或洪水区域中形成的干燥预混区域（预处理）。组合物和方法也可用于处理陆地表面和地下区域中的陆生生物。

10. 发明授权

US5939086A Compositions and methods for reducing the amount of contaminants in aquatic and terrestrial environments 失效
标题翻译：用于减少水生和陆地环境中污染物数量的组成和方法
公开(公告)号：US5939086A
公开(公告)日：1999-08-17
申请号：US863454
申请日：1997-05-27
申请人： Richard Levy
发明人： Richard Levy
IPC分类号： B01J20/26 , B09C1/00 , B09C1/02 , B09C1/08 , B09C1/10 , C02F1/28 , C02F1/68 , C02F3/10 , C09K3/32 , C12N11/08 , C12N11/10 , A01N25/08
CPC分类号： C02F3/108 , B09C1/00 , B09C1/002 , B09C1/02 , B09C1/08 , B09C1/10 , C02F1/285 , C02F1/681 , C12N11/08 , C12N11/10 , Y02W10/15
摘要： The invention provides contaminant-reducing agent delivery compositions that are useful for the control of organic or inorganic contaminants in aquatic or terrestrial environments. The compositions comprise one or more superabsorbent solid organic polymers and at least one contaminant-reducing agent. These superabsorbent polymers act as the primary carriers of one or more contaminant-reducing agents effective for the control of organic or inorganic contaminants in aquatic or terrestrial environments. Contaminant-reducing agents include film-forming agents, microbial agents, nutrient agents, and mixtures thereof. The invention also provides a method to entrap and accumulate organic and inorganic contaminants in one or more superabsorbent polymer compositions containing no contaminant-reducing agent. The invention also provides a method to entrap water in superabsorbent polymers to activate natural and applied microbial and nutrient contaminant-reducing agents in terrestrial environments.
摘要翻译：本发明提供了可用于控制水生或陆地环境中的有机或无机污染物的污染物减少剂递送组合物。组合物包含一种或多种超吸收性固体有机聚合物和至少一种污染物减少剂。这些超吸收性聚合物充当一种或多种有效用于控制水生或陆地环境中的有机或无机污染物的污染物减少剂的主要载体。污染减少剂包括成膜剂，微生物剂，营养剂及其混合物。本发明还提供了一种在不含有污染物减少剂的一种或多种超吸收性聚合物组合物中捕获和积聚有机和无机污染物的方法。本发明还提供了一种在超吸收聚合物中捕获水以在陆地环境中活化天然和应用的微生物和营养物质减少污染物的方法。

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