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1. 发明申请

US20100202673A1 TARGET TRACKING USING SURFACE SCANNER AND FOUR-DIMENSIONAL DIAGNOSTIC IMAGING DATA 审中-公开
标题翻译：使用表面扫描仪和四维诊断成像数据的目标跟踪
公开(公告)号：US20100202673A1
公开(公告)日：2010-08-12
申请号：US12754824
申请日：2010-04-06
申请人： Hui Zhang , Dongshan Fu , Gopinath Kuduvalli
发明人： Hui Zhang , Dongshan Fu , Gopinath Kuduvalli
IPC分类号： G06K9/00
CPC分类号： A61B6/08 , A61B5/113 , A61B6/4458 , A61B6/466 , A61B6/5235 , A61B6/5247 , A61B2090/366 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N2005/105 , A61N2005/1059
摘要： Tracking a pathological anatomy within a patient's body is described. A data model of a skin surface of the patient's body may be acquired using light reflected from the skin surface. The data model can be matched with skin surfaces reconstructed and/or interpolated from four-dimensional diagnostic imaging data, such as 4D CT data, to determine a temporal phase of the patient's respiratory motion. The identified temporal phase may then be used in conjunction with the diagnostic imaging data to identify a location of the pathological anatomy within the patient's body.
摘要翻译：描述了病人体内病理解剖的跟踪。可以使用从皮肤表面反射的光获取患者身体的皮肤表面的数据模型。数据模型可以与四维诊断成像数据（如4D CT数据）重建和/或内插的皮肤表面匹配，以确定患者呼吸运动的时间阶段。所识别的时间阶段然后可以与诊断成像数据结合使用以识别病人体内的病理解剖结构的位置。

2. 发明申请

US20090175406A1 Target tracking using surface scanner and four-dimensional diagnostic imaging data 有权
标题翻译：使用表面扫描仪和四维诊断成像数据进行目标跟踪
公开(公告)号：US20090175406A1
公开(公告)日：2009-07-09
申请号：US12008083
申请日：2008-01-07
申请人： Hui Zhang , Dongshan Fu , Gopinath Kuduvalli
发明人： Hui Zhang , Dongshan Fu , Gopinath Kuduvalli
IPC分类号： A61B6/00
CPC分类号： A61B6/08 , A61B5/113 , A61B6/4458 , A61B6/466 , A61B6/5235 , A61B6/5247 , A61B2090/366 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N2005/105 , A61N2005/1059
摘要： A method and apparatus for tracking a pathological anatomy within a patient's body is described. A data model of a skin surface of the patient's body may be acquired using light reflected from the skin surface. The data model can be matched with skin surfaces reconstructed and/or interpolated from four-dimensional (4D) diagnostic imaging data, such as 4D CT data, to determine a temporal phase of the patient's respiratory motion. The identified temporal phase may then be used in conjunction with the diagnostic imaging data to identify a location of the pathological anatomy within the patient's body.
摘要翻译：描述了用于跟踪患者体内的病理解剖结构的方法和装置。可以使用从皮肤表面反射的光获取患者身体的皮肤表面的数据模型。数据模型可以与四维（4D）诊断成像数据（例如4D CT数据）重建和/或内插的皮肤表面匹配，以确定患者呼吸运动的时间阶段。所识别的时间阶段然后可以与诊断成像数据结合使用以识别病人体内的病理解剖结构的位置。

3. 发明申请

US20100080354A1 SUBTRACTION OF A SEGMENTED ANATOMICAL FEATURE FROM AN ACQUIRED IMAGE 有权
标题翻译：从获取的图像中分离出分离的解剖特征
公开(公告)号：US20100080354A1
公开(公告)日：2010-04-01
申请号：US12242609
申请日：2008-09-30
申请人： Dongshan Fu , Gopinath Kuduvalli , Hui Zhang
发明人： Dongshan Fu , Gopinath Kuduvalli , Hui Zhang
IPC分类号： A61N5/10 , A61B5/00
CPC分类号： A61N5/1049 , A61N2005/1062 , G06T5/50 , G06T2207/20224
摘要： A system, method and apparatus for subtracting a synthetically-generated image, including a segmented anatomical feature, from an acquired image.
摘要翻译：一种用于从所获取的图像中减去合成生成的图像（包括分割的解剖特征）的系统，方法和装置。

4. 发明授权

US08457372B2 Subtraction of a segmented anatomical feature from an acquired image 有权
标题翻译：从获取的图像中减去分割的解剖特征
公开(公告)号：US08457372B2
公开(公告)日：2013-06-04
申请号：US12242609
申请日：2008-09-30
申请人： Dongshan Fu , Gopinath Kuduvalli , Hui Zhang
发明人： Dongshan Fu , Gopinath Kuduvalli , Hui Zhang
IPC分类号： G06K9/00
CPC分类号： A61N5/1049 , A61N2005/1062 , G06T5/50 , G06T2207/20224
摘要： A system, method and apparatus for subtracting a synthetically-generated image, including a segmented anatomical feature, from an acquired image.
摘要翻译：一种用于从所获取的图像中减去合成生成的图像（包括分割的解剖特征）的系统，方法和装置。

5. 发明授权

US07720196B2 Target tracking using surface scanner and four-dimensional diagnostic imaging data 有权
标题翻译：使用表面扫描仪和四维诊断成像数据进行目标跟踪
公开(公告)号：US07720196B2
公开(公告)日：2010-05-18
申请号：US12008083
申请日：2008-01-07
申请人： Hui Zhang , Dongshan Fu , Gopinath Kuduvalli
发明人： Hui Zhang , Dongshan Fu , Gopinath Kuduvalli
IPC分类号： A61N5/10
CPC分类号： A61B6/08 , A61B5/113 , A61B6/4458 , A61B6/466 , A61B6/5235 , A61B6/5247 , A61B2090/366 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N2005/105 , A61N2005/1059
摘要： A method and apparatus for tracking a pathological anatomy within a patient's body is described. A data model of a skin surface of the patient's body may be acquired using light reflected from the skin surface. The data model can be matched with skin surfaces reconstructed and/or interpolated from four-dimensional (4D) diagnostic imaging data, such as 4D CT data, to determine a temporal phase of the patient's respiratory motion. The identified temporal phase may then be used in conjunction with the diagnostic imaging data to identify a location of the pathological anatomy within the patient's body.
摘要翻译：描述了用于跟踪患者体内的病理解剖结构的方法和装置。可以使用从皮肤表面反射的光获取患者身体的皮肤表面的数据模型。数据模型可以与四维（4D）诊断成像数据（例如4D CT数据）重建和/或内插的皮肤表面匹配，以确定患者呼吸运动的时间阶段。所识别的时间阶段然后可以与诊断成像数据结合使用以识别病人体内的病理解剖结构的位置。

6. 发明申请

US20110160589A1 DYNAMIC TRACKING OF SOFT TISSUE TARGETS WITH ULTRASOUND IMAGES 审中-公开
标题翻译：具有超声图像的软组织目标的动态跟踪
公开(公告)号：US20110160589A1
公开(公告)日：2011-06-30
申请号：US13044364
申请日：2011-03-09
申请人： Dongshan Fu , Gopinath Kuduvalli , John Allison
发明人： Dongshan Fu , Gopinath Kuduvalli , John Allison
IPC分类号： A61B8/00
CPC分类号： A61N5/1049 , A61B8/08 , A61N5/1067 , A61N5/107 , A61N2005/1052 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061 , A61N2005/1062
摘要： Apparatus and methods of dynamically tracking a soft tissue target with ultrasound images are described. An apparatus includes an ultrasound imager coupled to a robotic arm. A method includes acquiring a first ultrasound (US) image of a patient with an ultrasound imager, determining a quality metric of the first US image, and adjusting one or more imaging parameters of the ultrasound imager if the quality metric of the acquired first US image is less than a quality threshold.
摘要翻译：描述了利用超声图像动态跟踪软组织靶的装置和方法。一种装置包括耦合到机器臂的超声波成像器。一种方法包括用超声波成像器获取患者的第一超声波（US）图像，确定第一美国图像的质量度量，以及如果所获取的第一美国图像的质量度量，则调整超声成像器的一个或多个成像参数小于质量阈值。

7. 发明授权

US07831073B2 Precision registration of X-ray images to cone-beam CT scan for image-guided radiation treatment 有权
标题翻译：精确配准X射线图像到锥束CT扫描图像引导辐射治疗
公开(公告)号：US07831073B2
公开(公告)日：2010-11-09
申请号：US11171842
申请日：2005-06-29
申请人： Dongshan Fu , Michael J. Saracen , Gopinath Kuduvalli
发明人： Dongshan Fu , Michael J. Saracen , Gopinath Kuduvalli
IPC分类号： G06K9/00
CPC分类号： A61N5/1049 , A61N5/1067 , A61N2005/1061 , G06T7/38
摘要： A method for precision registration of X-ray images to cone-beam CT scan for image-guided radiosurgery includes acquiring 2-D pre-treatment X-ray images of a region of interest, acquiring a 2-D X-ray image of the region of interest at approximately a time of treatment, registering the 2-D X-ray image with a corresponding 2-D pre-treatment X-ray image to obtain a 2-D registration result at approximately the time of treatment, and converting the 2-D registration result into a 3-D tracking result to track the region of interest.
摘要翻译：将X射线图像精确配准到用于图像引导放射外科的锥束CT扫描的方法包括获取感兴趣区域的2-D预处理X射线图像，获取X射线图像的2-D X射线图像在大约一段时间内处理感兴趣的区域，使用相应的2-D预处理X射线图像登记2-D X射线图像，以在大约在治疗时获得2-D登记结果，并将将2-D注册结果转换成跟踪感兴趣区域的3-D跟踪结果。

8. 发明申请

US20080159612A1 DRR generation using a non-linear attenuation model 审中-公开
标题翻译：使用非线性衰减模型的DRR生成
公开(公告)号：US20080159612A1
公开(公告)日：2008-07-03
申请号：US12074829
申请日：2008-03-05
申请人： Dongshan Fu , Gopinath Kuduvalli
发明人： Dongshan Fu , Gopinath Kuduvalli
IPC分类号： G06K9/00
CPC分类号： G06T11/008
摘要： A method and system are presented for generating a DRR of an anatomical region so that the visibility within the DDR of one or more skeletal reference structures is enhanced. 3D scan data, which have been obtained from a 3D scan of the object conducted at a 3D scan energy level, are provided. The 3D scan data are modified to compensated for a difference between the ratio of bone-to-tissue attenuation at the 3D scan energy level, and the ratio of bone-to-tissue attenuation at the intensity of the imaging beam which the DRR emulates. The modified 3D scan data are related to the raw 3D scan data by a non-linear, exponential relationship. A plurality of hypothetical rays are cast through the modified 3D scan data, from the known geometry of the imaging beam. The 3D scan data are integrated along each hypothetical ray, and the integrated values are projected onto an imaging plane.
摘要翻译：提出了一种用于产生解剖区域的DRR的方法和系统，使得一个或多个骨骼参考结构的DDR内的可见性增强。提供了从3D扫描能级进行的对象的3D扫描获得的3D扫描数据。 3D扫描数据被修改以补偿3D扫描能量级别的骨组织衰减比率与DRR模拟的成像束强度之间的骨组织衰减比。经修改的3D扫描数据通过非线性指数关系与原始3D扫描数据相关。通过成像光束的已知几何形状，通过修改的3D扫描数据投射多个假想射线。 3D扫描数据沿着每个假想射线进行积分，并将积分值投影到成像平面上。

9. 发明申请

US20080101673A1 Fiducial-less tracking with non-rigid image registration 有权
标题翻译：基于非刚性图像配准的基准跟踪
公开(公告)号：US20080101673A1
公开(公告)日：2008-05-01
申请号：US11999596
申请日：2007-12-05
申请人： Dongshan Fu , Gopinath Kuduvalli
发明人： Dongshan Fu , Gopinath Kuduvalli
IPC分类号： G06K9/00
CPC分类号： G06K9/32 , G06K2209/05 , G06T7/344 , G06T2207/10081 , G06T2207/10121 , G06T2207/10124 , G06T2207/30012
摘要： A method and system is presented for tracking patient motion in image guided surgery, using skeletal reference structures instead of fiducial markers.
摘要翻译：提出了一种方法和系统，用于跟踪图像引导手术中的患者运动，使用骨骼参考结构而不是基准标记。

10. 发明授权

US07187792B2 Apparatus and method for determining measure of similarity between images 有权
标题翻译：用于确定图像之间相似度测量的装置和方法
公开(公告)号：US07187792B2
公开(公告)日：2007-03-06
申请号：US10652717
申请日：2003-08-29
申请人： Dongshan Fu , Gopinath Kuduvalli
发明人： Dongshan Fu , Gopinath Kuduvalli
IPC分类号： G06K9/00
CPC分类号： A61N5/1049 , A61N5/1067 , A61N5/107 , A61N2005/1061 , A61N2005/1062 , G01N23/04 , G06T7/254 , G06T7/32 , G06T7/38 , G06T2207/10124 , G06T2207/30004
摘要： A method and system is presented in image-guided radiosurgery for determining the measure of similarity of two digital images, for example a 2D x-ray image and a 2D DRR synthesized from 3D scan data. A two-dimensional array of pixel values of a difference image is formed by subtracting each pixel value of the second image from the corresponding pixel value of the first image. The pattern intensity function is constructed by taking the summation of asymptotic functions of the gradients of the difference image. The neighborhood R is defined so as to allow the gradients of the difference image to be considered in at least four directions.
摘要翻译：在图像引导放射外科中提出了一种方法和系统，用于确定两个数字图像的相似度的测量，例如2D X射线图像和从3D扫描数据合成的2D DRR。通过从第一图像的相应像素值中减去第二图像的每个像素值来形成差分图像的像素值的二维阵列。通过对差分图像的渐变渐近函数求和，构建图案强度函数。定义邻域R以便在至少四个方向上考虑差分图像的梯度。

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