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1. 发明申请

US20130295124A1 ORF7 DEFICIENT VARICELLA VIRUS, VACCINE COMPRISING THE VIRUS AND USE THEREOF 有权
标题翻译： ORF7缺陷型VARICELLA病毒，包含病毒的疫苗及其用途
公开(公告)号：US20130295124A1
公开(公告)日：2013-11-07
申请号：US13387359
申请日：2010-07-27
申请人： Hua Zhu , Yimin Li , Ningshao Xia , Tong Cheng , Xiangzhong Ye
发明人： Hua Zhu , Yimin Li , Ningshao Xia , Tong Cheng , Xiangzhong Ye
IPC分类号： C12N7/00 , C12N15/86 , A61K39/25
CPC分类号： C12N7/00 , A61K39/12 , A61K39/25 , A61K2039/5254 , C07K14/005 , C12N15/86 , C12N2710/16722 , C12N2710/16734
摘要： Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
摘要翻译：提供了ORF7缺陷型水痘病毒，包含该病毒及其用途的疫苗，以及用于生产该病毒的方法。

2. 发明授权

US09885020B2 ORF7 deficient varicella virus, vaccine comprising the virus and use thereof 有权
公开(公告)号：US09885020B2
公开(公告)日：2018-02-06
申请号：US13387359
申请日：2010-07-27
申请人： Hua Zhu , Yimin Li , Ningshao Xia , Tong Cheng , Xiangzhong Ye
发明人： Hua Zhu , Yimin Li , Ningshao Xia , Tong Cheng , Xiangzhong Ye
IPC分类号： C12N7/00 , A61K39/25 , C07K14/005 , C12N15/86 , A61K39/12 , A61K39/00
CPC分类号： C12N7/00 , A61K39/12 , A61K39/25 , A61K2039/5254 , C07K14/005 , C12N15/86 , C12N2710/16722 , C12N2710/16734
摘要： Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.

3. 发明授权

US09222090B2 RNA interference target for treating AIDS 有权
标题翻译：治疗艾滋病的RNA干扰目标
公开(公告)号：US09222090B2
公开(公告)日：2015-12-29
申请号：US13584319
申请日：2012-08-13
申请人： Tong Cheng , Tao Zhang , Yali Zhang , Ji Miao , Jun Zhang , Ningshao Xia
发明人： Tong Cheng , Tao Zhang , Yali Zhang , Ji Miao , Jun Zhang , Ningshao Xia
IPC分类号： C12N15/11 , C12N15/113
CPC分类号： C12N15/1132 , C12N2310/11 , C12N2310/12 , C12N2310/14
摘要： The RNAi target sequences, which could be used for treating AIDS through targeting HIV. Based on the target sequences, recombinant expression vectors, packaging vectors and cells were constructed, which express siRNA and/or miRNA and/or ribozyme and/or antisense oligonucleotide for targeting HIV. And the applications of said recombinant expression vectors, packaging vectors and cells in preparing medicament for treating AIDS.
摘要翻译： RNAi靶序列，可用于通过靶向HIV来治疗艾滋病。基于靶序列，构建重组表达载体，包装载体和细胞，其表达用于靶向HIV的siRNA和/或miRNA和/或核酶和/或反义寡核苷酸。以及所述重组表达载体，包装载体和细胞在制备用于治疗AIDS的药物中的应用。

4. 发明申请

US20110243904A1 RNA INTERFERENCE TARGET FOR TREATING AIDS 审中-公开
标题翻译：用于治疗艾滋病的RNA干扰目标
公开(公告)号：US20110243904A1
公开(公告)日：2011-10-06
申请号：US12602005
申请日：2008-06-02
申请人： Tong Cheng , Tao Zhang , Yali Zhang , Ji Miao , Jun Zhang , Ningshao Xia
发明人： Tong Cheng , Tao Zhang , Yali Zhang , Ji Miao , Jun Zhang , Ningshao Xia
IPC分类号： A61K48/00 , C07H21/04 , C12N15/63 , C07H21/02 , C12N15/85 , C12N5/10 , C12N1/00 , A61K31/713 , A61K31/7088 , A61K35/12 , A61P31/18
CPC分类号： C12N15/1132 , C12N2310/11 , C12N2310/12 , C12N2310/14
摘要： The present invention relates to RNA interference target sequence targeting HIV for the treatment of AIDS. Based on the target sequence, recombinant expression vectors, packaging vectors and cells were constructed, which express a siRNA and/or a miRNA and/or a ribozyme and/or an antisense oligonucleotide targeting HIV. Also provided is the use of the recombinant expression vectors, packaging vectors and recombinant cells in the manufacture of a medicament for the treatment of AIDS.
摘要翻译：本发明涉及靶向用于治疗AIDS的HIV的RNA干扰靶序列。基于靶序列，构建重组表达载体，包装载体和细胞，其表达siRNA和/或miRNA和/或靶向HIV的核酶和/或反义寡核苷酸。还提供了重组表达载体，包装载体和重组细胞在制备用于治疗AIDS的药物中的用途。

5. 发明授权

US08963836B2 Method and system for gesture-based human-machine interaction and computer-readable medium thereof 有权
标题翻译：用于基于手势的人机交互的方法和系统及其计算机可读介质
公开(公告)号：US08963836B2
公开(公告)日：2015-02-24
申请号：US13697518
申请日：2011-08-16
申请人： Tong Cheng , Shuai Yue
发明人： Tong Cheng , Shuai Yue
IPC分类号： G06F3/0488 , G06F3/01
CPC分类号： G06F3/04883 , G06F3/017
摘要： A method and system for gesture-based human-machine interaction and computer-readable medium are provided. The system includes a capturing module, a positioning module, and a transforming module. The method includes the steps of: capturing images from a user's video streams, positioning coordinates of three or more predetermined color blocks in the foreground, simulating movements of a mouse according to the coordinates of the first color block, and simulating click actions of the mouse according to the coordinates of the other color blocks. The embodiments according to the current disclosure position coordinates of a plurality of color blocks through processing the captured user's video streams, and simulate mouse actions according to the coordinates of the color blocks. Processing apparatuses like computers may be extended to facilitate gesture-based human-machine interactions through a very simple way, and a touch-sensitive interaction effect can be simulated, without the presence of a touch screen.
摘要翻译：提供了一种用于基于手势的人机交互和计算机可读介质的方法和系统。该系统包括捕获模块，定位模块和变换模块。该方法包括以下步骤：从用户的视频流捕获图像，在前景中定位三个或更多个预定颜色块的坐标，根据第一颜色块的坐标模拟鼠标的移动，以及模拟鼠标的点击动作根据其他颜色块的坐标。根据当前公开的实施例通过处理捕获的用户的视频流来定位多个颜色块的坐标，并且根据颜色块的坐标来模拟鼠标动作。可以通过非常简单的方式来扩展诸如计算机的处理装置以促进基于手势的人机交互，并且可以模拟触敏交互效果，而不存在触摸屏。

6. 发明申请

US20130162532A1 METHOD AND SYSTEM FOR GESTURE-BASED HUMAN-MACHINE INTERACTION AND COMPUTER-READABLE MEDIUM THEREOF 有权
标题翻译：基于人机交互的方法与系统及其可计算机可读介质
公开(公告)号：US20130162532A1
公开(公告)日：2013-06-27
申请号：US13697518
申请日：2011-08-16
申请人： Tong Cheng , Shuai Yue
发明人： Tong Cheng , Shuai Yue
IPC分类号： G06F3/0488
CPC分类号： G06F3/04883 , G06F3/017
摘要： A method and system for gesture-based human-machine interaction and computer-readable medium are provided. The system includes a capturing module, a positioning module, and a transforming module. The method includes the steps of: capturing images from a user's video streams, positioning coordinates of three or more predetermined color blocks in the foreground, simulating movements of a mouse according to the coordinates of the first color block, and simulating click actions of the mouse according to the coordinates of the other color blocks. The embodiments according to the current disclosure position coordinates of a plurality of color blocks through processing the captured user's video streams, and simulate mouse actions according to the coordinates of the color blocks. Processing apparatuses like computers may be extended to facilitate gesture-based human-machine interactions through a very simple way, and a touch-sensitive interaction effect can be simulated, without the presence of a touch screen.
摘要翻译：提供了一种用于基于手势的人机交互和计算机可读介质的方法和系统。该系统包括捕获模块，定位模块和变换模块。该方法包括以下步骤：从用户的视频流捕获图像，在前景中定位三个或更多个预定颜色块的坐标，根据第一颜色块的坐标模拟鼠标的移动，以及模拟鼠标的点击动作根据其他颜色块的坐标。根据当前公开的实施例通过处理捕获的用户的视频流来定位多个颜色块的坐标，并且根据颜色块的坐标来模拟鼠标动作。可以通过非常简单的方式来扩展诸如计算机的处理装置以促进基于手势的人机交互，并且可以模拟触敏交互效果，而不存在触摸屏。

7. 发明申请

US20080305100A1 Activated Protein C Inhibits Undesirable Effects of Plasminogen Activator in the Brain 审中-公开
标题翻译：活化蛋白C抑制纤溶酶原激活剂对脑的不良影响
公开(公告)号：US20080305100A1
公开(公告)日：2008-12-11
申请号：US11632850
申请日：2005-07-25
申请人： Berislav V. Zlokovic , Dong Liu , Tong Cheng , Huang Guo
发明人： Berislav V. Zlokovic , Dong Liu , Tong Cheng , Huang Guo
IPC分类号： A61K38/48 , C40B30/06 , A61P9/00
CPC分类号： A61K38/4866 , A61K38/49 , A61K2300/00
摘要： Activated protein C (APC), a prodrug, and/or a variant of APC may be used to inhibit undesirable effects of plasminogen activator: e.g., apoptosis or cell death of neurons and endothelial cells, brain hemorrhage or intracerebral bleeding, and/or tissue damage in a subject's brain. Inhibition appears to act through the extrinsic pathway of death receptor signal transduction. This represents an improvement in treatment using plasminogen activator (e.g., fibrinolysis). By reducing undesirable effects, the window for fibrinolytic therapy by plasminogen activator may be widened.
摘要翻译：活化蛋白C（APC），APC的前体药物和/或变体可用于抑制纤溶酶原激活物的不期望的作用：例如神经元和内皮细胞的凋亡或细胞死亡，脑出血或脑内出血和/或组织受试者脑部的损伤抑制似乎通过死亡受体信号转导的外在途径起作用。这表示使用纤溶酶原激活剂（例如，纤维蛋白溶解）治疗的改善。通过减少不良影响，纤溶酶原激活剂的纤维蛋白溶解治疗窗可能会扩大。

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