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    • 1. 发明授权
    • Chromatography column
    • 色谱柱
    • US4496461A
    • 1985-01-29
    • US505532
    • 1983-06-17
    • Gordon LeekeChaokang ChuNils L. Dailey
    • Gordon LeekeChaokang ChuNils L. Dailey
    • B01J20/281B01D15/08G01N30/60G01N30/88G01N33/28
    • G01N30/6069B01D15/22G01N30/6091G01N33/28
    • A chromatography column for effecting chromatographic separation of at least two components of a sample flowing through the column. The column comprises a housing and at least one solid stationary phase within the housing. The stationary phase has chromatographic functionality and is effective for chromatographic separation. Means are provided for radially distributing the sample through the stationary phase and for collecting the sample after the sample has flowed through the stationary phase. The stationary phase comprises:(a) a swellable fibrous matrix in sheet form having chromatographic functionality and being effective for chromatographic separation, spirally wound around the longitudinal axis of the solid stationary phase to form a plurality of layers around the axis; and(b) a spacer means between each layer for permitting controlled swelling thereof and enhancing the distribution of sample flowing radially through the stationary phase.The solid stationary phase may be fabricated into a disposable cartridge for placement in the housing. A plurality of cartridges may be used either in series or parallel flow configuration in a single housing.
    • 色谱柱,用于对流过柱的样品的至少两种组分进行色谱分离。 该柱包括壳体和壳体内的至少一个固体固定相。 固定相具有色谱功能,可用于色谱分离。 提供了用于通过固定相径向分布样品并在样品流过固定相之后收集样品的装置。 固定相包括:(a)片状形式的可溶胀纤维基质,具有色谱功能并且对于色谱分离是有效的,螺旋缠绕在固体固定相的纵向轴线周围以围绕轴线形成多个层; 和(b)每个层之间的间隔装置,用于允许其受控的溶胀,并增强径向流过固定相的样品的分布。 可以将固体固定相制造成用于放置在壳体中的一次性盒。 可以在单个壳体中串联或并联流动配置中使用多个墨盒。