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1. 发明授权

US08383134B2 Biodegradable material based on opened starch 有权
标题翻译：基于开放淀粉的可生物降解材料
公开(公告)号：US08383134B2
公开(公告)日：2013-02-26
申请号：US12529526
申请日：2008-02-29
申请人： Gijsbertus Gerardus Petrus Van De Wijdeven
发明人： Gijsbertus Gerardus Petrus Van De Wijdeven
IPC分类号： A61K9/00 , A61K47/00 , A61F2/00 , C08L3/00 , C08B31/00 , B29C47/00 , B29B7/00
CPC分类号： A61K9/0024 , A61K9/146 , A61K47/36 , C08B30/12 , C08B30/20 , C08J3/18 , C08J2303/02 , C08J2303/12 , C08L3/02 , C08L3/12 , C08L2201/06 , C08L2205/02 , C12P19/04 , C08L2666/26 , C08L2666/02
摘要： The present application relates to a biodegradable material comprising opened starch or a mixture of opened starch and destructurised starch. The biodegradable material comprises about 50 to about 100 wt. % of opened starch or of a mixture of opened starch and destructurized starch, based on the total weight of the biodegradable material, said biodegradable material having a bulk density of 1.0 to 1.5 kg/dm. The biodegradable material is used for manufacturing biodegradable shaped articles, wherein said biodegradable shaped articles are suitable for delivery of a biologically or pharmaceutically active component in or to a vertebrate, e.g. a mammal.
摘要翻译：本申请涉及包含开放淀粉或开放淀粉和破坏性淀粉的混合物的可生物降解材料。生物降解材料包含约50至约100wt。基于可生物降解材料的总重量的开放淀粉或开放淀粉和变性淀粉的混合物的％，所述生物可降解材料的堆积密度为1.0至1.5kg / dm 2。可生物降解的材料用于制造可生物降解的成型制品，其中所述可生物降解的成形制品适于将生物或药学活性成分递送至脊椎动物或其中。哺乳动物

2. 发明授权

US08486439B2 Parenteral formulation 有权
标题翻译：肠胃外制剂
公开(公告)号：US08486439B2
公开(公告)日：2013-07-16
申请号：US12529525
申请日：2008-02-29
申请人： Gijsbertus Gerardus Petrus Van De Wijdeven
发明人： Gijsbertus Gerardus Petrus Van De Wijdeven
IPC分类号： A61F2/00 , A61K47/00 , B29C45/00 , B29C47/00
CPC分类号： A61K9/0024 , A61K9/1652
摘要： The present invention relates to a kinetic implant comprising(a) biodegradable material comprising opened starch, destructurized starch or a mixture of opened starch and destructurized starch, (b) a biologically or pharmaceutically active substance; and (c) a stabilizing component stabilizing the biologically or pharmaceutically active substance. The biodegradable material comprises about 50 to about 100 wt. % of opened starch, destructurized starch or a mixture of opened starch, based on the total weight of the biodegradable material, the biodegradable material having a bulk density of 1.0 to 1.5 kg/dm3. The kinetic implant has a length :diameter ratio of more than 4, provided that the length of the kinetic implant is between 1 mm to 50 mm. The kinetic implant has a weight such that it can be provided with an amount of kinetic energy in the range of 0.1 to 10 J.
摘要翻译：本发明涉及一种动力学植入物，其包含（a）包含开放淀粉，变性淀粉或开放淀粉和无序结构淀粉的混合物的生物可降解材料，（b）生物或药学活性物质; 和（c）使生物或药学活性物质稳定的稳定化成分。生物降解材料包含约50至约100wt。基于可生物降解材料的总重量的开放淀粉的％，变性淀粉或开放淀粉的混合物，生物可降解材料的堆积密度为1.0至1.5kg / dm 3。动力学植入物的长度：直径比大于4，只要动力学植入物的长度在1mm至50mm之间。动力学植入物的重量使得其可以具有在0.1至10J范围内的一定量的动能。

3. 发明申请

US20100015185A1 BIODEGRADABLE MATERIAL BASED ON OPENED STARCH 有权
标题翻译：基于开放式STARCH的生物可降解材料
公开(公告)号：US20100015185A1
公开(公告)日：2010-01-21
申请号：US12529526
申请日：2008-02-29
申请人： Gijsbertus Gerardus Petrus Van De Wijdeven
发明人： Gijsbertus Gerardus Petrus Van De Wijdeven
IPC分类号： A61K9/00 , C08B30/12 , A61K47/36
CPC分类号： A61K9/0024 , A61K9/146 , A61K47/36 , C08B30/12 , C08B30/20 , C08J3/18 , C08J2303/02 , C08J2303/12 , C08L3/02 , C08L3/12 , C08L2201/06 , C08L2205/02 , C12P19/04 , C08L2666/26 , C08L2666/02
摘要： The present application relates to a biodegradable material comprising opened starch or a mixture of opened starch and destructurised starch. The biodegradable material comprises about 50 to about 100 wt. % of opened starch or of a mixture of opened starch and destructurised starch, based on the total weight of the biodegradable material, said biodegradable material having a bulk density of 1.0 to 1.5 kg/dm. The biodegradable material is used for manufacturing biodegradable shaped articles, wherein said biodegradable shaped articles are suitable for delivery of a biologically or pharmaceutically active component in or to a vertebrate, e.g. a mammal.
摘要翻译：本申请涉及包含开放淀粉或开放淀粉和破坏性淀粉的混合物的可生物降解材料。生物降解材料包含约50至约100wt。基于可生物降解材料的总重量，开放淀粉或开放淀粉和破坏淀粉的混合物的％，所述生物可降解材料的堆积密度为1.0至1.5kg / dm 2。可生物降解的材料用于制造可生物降解的成型制品，其中所述可生物降解的成形制品适于将生物或药学活性成分递送至脊椎动物或其中。哺乳动物

4. 发明申请

US20100080839A1 PARENTERAL FORMULATION 有权
标题翻译：住院配方
公开(公告)号：US20100080839A1
公开(公告)日：2010-04-01
申请号：US12529525
申请日：2008-02-29
申请人： Gijsbertus Gerardus Petrus Van De Wijdeven
发明人： Gijsbertus Gerardus Petrus Van De Wijdeven
IPC分类号： A61F2/00 , A61K47/36 , B29C45/00
CPC分类号： A61K9/0024 , A61K9/1652
摘要： The present invention relates to a kinetic implant comprising (a) biodegradable material comprising opened starch, destructurised starch or a mixture of opened starch and destructurised starch, (b) a biologically or pharmaceutically active substance; and (c) a stabilising component stabilising the biologically or pharmaceutically active substance. The biodegradable material comprises about 50 to about 100 wt. % of opened starch, destructurised starch or a mixture of opened starch, based on the total weight of the biodegradable material, said biodegradable material having a bulk density of 1.0 to 1.5 kg/dm3. The kinetic implant has a length:diameter ratio of more than 4, provided that the length of the kinetic implant is between 1 mm to 50 mm. The kinetic implant has a weight such that it can be provided with an amount of kinetic energy in the range of 0.1 to 10 J.
摘要翻译：本发明涉及动植入物，其包含（a）包含开放淀粉，破坏性淀粉或开放淀粉和破坏性淀粉的混合物的生物可降解材料，（b）生物或药学活性物质; 和（c）使生物或药学活性物质稳定的稳定化成分。生物降解材料包含约50至约100wt。基于可生物降解材料的总重量的开放淀粉，破坏性淀粉或开放淀粉的混合物的％，所述生物可降解材料的堆积密度为1.0至1.5kg / dm 3。动力学植入物的长度：直径比大于4，只要动力学植入物的长度在1mm至50mm之间。动力学植入物的重量使得其可以具有在0.1至10J范围内的一定量的动能。

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