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1. 发明授权

US5120662A Multilayer solid phase immunoassay support and method of use 失效
标题翻译：多层固相免疫测定法及其使用方法
公开(公告)号：US5120662A
公开(公告)日：1992-06-09
申请号：US532489
申请日：1990-06-04
申请人： Emerson W. Chan , Werner Schulze , William G. Robey , Brian P. Braun , Cynthia K. Daluga , Andreas A. Kapsalis , Kevin M. Knigge , John E. Stephens , Joseph J. Stojak, II , David S. Vallaris , Benton A. Durley, deceased , James D. Defreese , Carl W. Merkh
发明人： Emerson W. Chan , Werner Schulze , William G. Robey , Brian P. Braun , Cynthia K. Daluga , Andreas A. Kapsalis , Kevin M. Knigge , John E. Stephens , Joseph J. Stojak, II , David S. Vallaris , Benton A. Durley, deceased , James D. Defreese , Carl W. Merkh
IPC分类号： G01N33/543 , G01N33/569
CPC分类号： G01N33/54306 , G01N33/56988 , Y10S436/808 , Y10S436/809
摘要： An immunoassay which is capable of simultaneously detecting any desired number of antigens of one infectious agent, or combinations of antigens of several infectious agents, or any desired number of immunoglobulins of one infectious agent, or combinations of immunoglobulins of several infectious agents on a single solid support. A test sample is contacted with a solid support on which one or more antigens are immobilized as discrete test sites. Antigen-antibody complexes are formed and detected on the solid support.
摘要翻译：能够同时检测一种感染因子的任何所需数量的抗原或几种感染因子的抗原的组合或一种感染因子的任何所需数量的免疫球蛋白或几种感染因子的免疫球蛋白的组合在单一固体上的免疫测定支持。将测试样品与其上固定有一种或多种抗原的固体支持物作为离散测试位点接触。在固体支持物上形成并检测抗原 - 抗体复合物。

2. 发明授权

US5356772A Process for preparing an improved western blot immunoassay 失效
标题翻译：制备改进的蛋白质印迹免疫测定法
公开(公告)号：US5356772A
公开(公告)日：1994-10-18
申请号：US622311
申请日：1990-12-05
申请人： Emerson W. Chan , William G. Robey , Werner Schulze
发明人： Emerson W. Chan , William G. Robey , Werner Schulze
IPC分类号： C12P21/08 , G01N33/543 , G01N33/561 , G01N33/569 , G01N33/574 , C12Q1/70 , C12P19/38 , G01N33/53
CPC分类号： G01N33/54306 , G01N33/56988 , Y10S435/974 , Y10S930/221
摘要： The present invention encompasses an improved immunoassay method which involves the simultaneous transfer of multiple antigens onto a single solid support. The antigens which may be utilized by this method may be either naturally or recombinantly produced and may be purified on a variety of electrophoresis gels. This method is particularly useful to provide an extremely sensitive multiple component assay using essentially pure antigenic polypeptides capable of detecting the presence or antibodies to HIV-1 or HIV-2 viruses in infected patients.
摘要翻译：本发明包括改进的免疫测定方法，其涉及将多种抗原同时转移到单一固体支持物上。可以通过该方法使用的抗原可以是天然的或重组产生的，并且可以在各种电泳凝胶上纯化。该方法特别有用的是提供使用能够检测感染患者中HIV-1或HIV-2病毒的存在或抗体的基本上纯的抗原多肽的极度敏感的多重成分测定。

3. 发明授权

US08474329B2 Pipe-shaped sensor device 有权
标题翻译：管状传感器装置
公开(公告)号：US08474329B2
公开(公告)日：2013-07-02
申请号：US12918561
申请日：2009-02-05
申请人： Werner Schulze , Michael Wald
发明人： Werner Schulze , Michael Wald
IPC分类号： G01L1/00
CPC分类号： A61F2/76 , A61F2/60 , A61F2002/30359 , A61F2002/7635 , A61F2002/7645 , A61F2002/7695 , A61F2220/0033 , G01L5/226
摘要： The invention relates to a sensor device (1) for measuring an axial force in the longitudinal pipe direction of a pipe (4) and/or at least one torque, having a measuring element (2) comprising an adapter connection (3) connected to the pipe by means of a flanged socket part, by means of which the pipe can be fixedly coupled to an adjustment adapter (5), wherein the axial force and the torque can be fed into the adjustment adapter and can be measured by means of strain gauges (11, 12) disposed in a sensor area (9) between the adapter connection and an end of the flanged socket part (6) opposite the adapter connection at strain gauge locations, wherein the flanged socket part having the sensor area is designed in a pipe shape, wherein the sensor area extends from the adapter connection to the end of the flanged socket part and has a smaller outer diameter than the end of the flanged socket part, wherein the end of the pipe facing the adapter connection and extending past the end of the flanged socket part toward the adapter connection is force decoupled from the sensor area and from the adapter connection, and wherein at least three strain gauge measuring locations are disposed on the circumference of the sensor area.
摘要翻译：本发明涉及一种用于测量管道（4）的纵向管道方向上的轴向力和/或至少一个扭矩的传感器装置（1），其具有测量元件（2），该测量元件（2）包括连接到管道通过法兰的插座部分，通过该管道可以将管道固定地联接到调节适配器（5），其中轴向力和扭矩可以被馈送到调节适配器中，并且可以通过应变来测量设置在传感器区域（9）之间的传感器区域（9）中的应变计位置处的适配器连接与法兰插座部分（6）的与适配器连接件相对的端部，其中具有传感器区域的带凸缘的插座部分被设计为管形，其中传感器区域从适配器连接件延伸到法兰插座部分的端部，并且具有比带凸缘的插座部件的端部更小的外径，其中管的端部面向适配器连接并延伸越过 f的结尾朝向适配器连接的凸缘插座部分是从传感器区域和适配器连接部分解耦的，并且其中至少三个应变计测量位置设置在传感器区域的圆周上。

4. 发明授权

US06955098B2 Force sensor with two force input elements 失效
标题翻译：强力传感器带有两个强力输入元件
公开(公告)号：US06955098B2
公开(公告)日：2005-10-18
申请号：US10893928
申请日：2004-07-20
申请人： Werner Schulze , Otto Kuhlmann
发明人： Werner Schulze , Otto Kuhlmann
IPC分类号： G01G3/14 , G01L1/22 , G01L1/10
CPC分类号： G01L1/2243 , G01G3/1412 , G01G3/1414
摘要： A force sensor with two force input elements to which a force to be measured and a support force are applied. The two force input elements are substantially rotationally symmetrical and are axially spaced apart, and the force to be measured and the support force are applied in radial directions. A spring element, arranged axially between the two force input elements connects these elements and its load-dependent deformation is converted into an electrical signal. A suppression of transverse forces is achieved in a purely mechanical manner so that the influence of transverse forces on the output signal of the force sensor are negligible. Both force input elements are additionally connected to each other by a guide element which encloses the spring element and which has two parallel guide connectors. The guide element is softer in the direction of the force to be measured than in a direction perpendicular thereto.
摘要翻译：具有两个力输入元件的力传感器，施加要测量的力和支撑力。两个力输入元件基本上是旋转对称的并且轴向间隔开，并且被测量的力和支撑力沿径向方向施加。轴向布置在两个力输入元件之间的弹簧元件连接这些元件，并且其负载相关的变形被转换成电信号。以纯粹的机械方式实现横向力的抑制，使得横向力对力传感器的输出信号的影响是可以忽略的。两个力输入元件另外通过包围弹簧元件并具有两个平行导向连接器的导向元件相互连接。引导元件在被测量的方向上比在与其垂直的方向上更软。

5. 发明申请

US20110060249A1 PIPE-SHAPED SENSOR DEVICE 有权
标题翻译：管式传感器装置
公开(公告)号：US20110060249A1
公开(公告)日：2011-03-10
申请号：US12918561
申请日：2009-02-05
申请人： Werner Schulze , Michael Wald
发明人： Werner Schulze , Michael Wald
IPC分类号： A61B5/103 , G01L1/00 , G01L3/00
CPC分类号： A61F2/76 , A61F2/60 , A61F2002/30359 , A61F2002/7635 , A61F2002/7645 , A61F2002/7695 , A61F2220/0033 , G01L5/226
摘要： The invention relates to a sensor device (1) for measuring an axial force in the longitudinal pipe direction of a pipe (4) and/or at least one torque, having a measuring element (2) comprising an adapter connection (3) connected to the pipe by means of a flanged socket part, by means of which the pipe can be fixedly coupled to an adjustment adapter (5), wherein the axial force and the torque can be fed into the adjustment adapter and can be measured by means of strain gauges (11, 12) disposed in a sensor area (9) between the adapter connection and an end of the flanged socket part (6) opposite the adapter connection at strain gauge locations, wherein the flanged socket part having the sensor area is designed in a pipe shape, wherein the sensor area extends from the adapter connection to the end of the flanged socket part and has a smaller outer diameter than the end of the flanged socket part, wherein the end of the pipe facing the adapter connection and extending past the end of the flanged socket part toward the adapter connection is force decoupled from the sensor area and from the adapter connection, and wherein at least three strain gauge measuring locations are disposed on the circumference of the sensor area.
摘要翻译：本发明涉及一种用于测量管道（4）的纵向管道方向上的轴向力和/或至少一个扭矩的传感器装置（1），其具有测量元件（2），该测量元件（2）包括连接到管道通过法兰的插座部分，通过该管道可以将管道固定地联接到调节适配器（5），其中轴向力和扭矩可以被馈送到调节适配器中，并且可以通过应变来测量设置在传感器区域（9）之间的传感器区域（9）中的应变计位置处的适配器连接与法兰插座部分（6）的与适配器连接件相对的端部，其中具有传感器区域的带凸缘的插座部分被设计为管形，其中传感器区域从适配器连接件延伸到法兰插座部分的端部，并且具有比带凸缘的插座部件的端部更小的外径，其中管的端部面向适配器连接并延伸越过 f的结尾朝向适配器连接的凸缘插座部分是从传感器区域和适配器连接部分解耦的，并且其中至少三个应变计测量位置设置在传感器区域的圆周上。

6. 发明授权

US06365847B1 Weight sensor 有权
标题翻译：重量传感器
公开(公告)号：US06365847B1
公开(公告)日：2002-04-02
申请号：US09576413
申请日：2000-05-22
申请人： Michael Müller , Ulrich Bajohr , Rudolf Müller , Werner Schulze , Detlef Erben , Herbert Engelhardt
发明人： Michael Müller , Ulrich Bajohr , Rudolf Müller , Werner Schulze , Detlef Erben , Herbert Engelhardt
IPC分类号： G01G2124
CPC分类号： G01G23/012 , G01G7/02 , G01G21/244
摘要： In a weight sensor operating according to the principle of electromagnetic force compensation, the essential parts are fabricated from a single block of material. The weight sensor has a load receiver (10), which is connected through an upper guide (12) and a lower (11) guide to the housing-integral base body (1) of the material block. The weight sensor also has several force-reduction translating levers (21,22; 24, 25,25′; 27,27′,28) and coupling elements (18,18′, 23, 26,26′) between the translating levers (21, 22; 24 ,25,25′; 27,27′,28). The housing-integral base body (1) projects in the direction of the load receiver (10), extends into the space between the two guides (11, 12) and forms a support point for the first translating lever (21, 22). The weight sensor is equipped with a coil (34), which is fastened at the longer lever arm (28) of the last translating lever (27,27′,28,29,29′) and is situated in the magnetic field of a permanent magnet. To reduce the overall height and to receive higher loads, at least one translating lever is at least partially split into two partial levers (25, 25′; 27,27′; 29,29′). At least one coupling element is split into two partial coupling elements (26,26′; 38,38′). The partial levers and the partial coupling elements are arranged symmetrically on both sides of the projecting part (3) of the base body (1).
摘要翻译：在根据电磁力补偿原理运行的重量传感器中，基本部件由单块材料制成。重量传感器具有负载接收器（10），其通过上引导件（12）和下导向件（11）连接到材料块的壳体一体式基体（1）上。重量传感器还具有几个减压平移杆（21,22; 24,25,27'，27,27'，28）和在平移杆之间的联接元件（18,18'，23,26,26'）（21,22; 24,25,25'; 27,27'，28）。壳体一体式基体（1）沿负载接收器（10）的方向突出，延伸到两个引导件（11,12）之间的空间中并形成用于第一平移杆（21,22）的支撑点。该重量传感器配备有一个线圈（34），该线圈固定在最后一个平移杆（27,27'，28,29,29'）的较长的杠杆臂（28）上并且位于一个永久磁铁为了降低总体高度并承受更高的载荷，至少一个平移杠杆至少部分地分成两个部分杠杆（25,25'; 27,27'; 29,29'）。至少一个耦合元件被分成两个部分耦合元件（26,26'; 38,38'）。部分杆和部分联接元件对称地布置在基体（1）的突出部分（3）的两侧上。

7. 发明授权

US5525762A Balance with force support 失效
标题翻译：平衡力量支持
公开(公告)号：US5525762A
公开(公告)日：1996-06-11
申请号：US370605
申请日：1995-01-10
申请人： Gunther Maaz , Matthias Eger , Werner Schulze , Christoph Berg , Michael Muller , Eberhard Lubke
发明人： Gunther Maaz , Matthias Eger , Werner Schulze , Christoph Berg , Michael Muller , Eberhard Lubke
IPC分类号： G01G21/24 , G01G3/08
CPC分类号： G01G21/244
摘要： Disclosed is a balance with a first parallel guide (3, 3') which resiliently connector a load receiver (2) to an area (5, 5') fixed to the housing and which is resiliently deformed under the influence of the weight to be measured, and with a second, softer parallel guide (8) which is connected by its one end to the load receiver (2) and by its other (11) end via a force receiver which is at least approximately without displacement to the area (5, 5') fixed to the housing and which transfers as a result thereof a fraction of the force of the weight onto the force measuring receiver that both parallel guides (3, 3', 8) exhibit at least approximately the same height and the same length and are arranged close to one another laterally. The second parallel guide is advantageously locate between two partial areas (3, 5, and 3', 5') of the first parallel guide.
摘要翻译：公开了一种与将负载接收器（2）弹性地连接到固定到壳体的区域（5,5'）的第一平行导轨（3,3'）的平衡，并且在重量的影响下弹性变形并且具有第二较软的平行导向器（8），其通过其一端连接到负载接收器（2）和另一端（11）端部，该力接收器至少大致没有位移到该区域 5'，5'）固定到壳体，并且由此将重量的力的一部分转移到力测量接收器上，两个平行导轨（3,3'，8）表现出至少大致相同的高度，并且相同的长度并横向布置成彼此靠近。第二平行引导件有利地位于第一平行引导件的两个部分区域（3,5和3'，5'）之间。

8. 发明授权

US4709859A High pressure washing apparatus 失效
标题翻译：高压清洗设备
公开(公告)号：US4709859A
公开(公告)日：1987-12-01
申请号：US705066
申请日：1985-02-25
申请人： Werner Schulze , Josef Gerich
发明人： Werner Schulze , Josef Gerich
IPC分类号： B05B1/30 , B05B12/00 , B05B15/06 , B05B9/01
CPC分类号： B05B12/002 , B05B1/3013 , B05B15/065
摘要： In a high pressure washing apparatus with a spray handle and a flexible hose leading to it, in order to create the possibility of rotation between the hose and the spray handle, it is proposed that the spray handle should display a barrel, for connecting to the hose, into which can be inserted in sealed fashion a hose nipple connected to the hose end, that a bearing surface be provided on the spray handle, against which rests a flange connected with the hose nipple, and thereby preventing the hose nipple from being pulled from the barrel, and that the bearing surface and/or the hose nipple flange surround the hose nipple in ring form, and be rotatable with respect to one another around the longitudinal axis of the hose nipple.
摘要翻译：在具有喷雾手柄和通向其的柔性软管的高压清洗装置中，为了在软管和喷雾手柄之间产生旋转的可能性，建议喷雾手柄应显示一个筒体，用于连接到软管，其可以以密封方式插入连接到软管端的软管接头，在喷雾手柄上设置一个支承表面，与该软管接头相连接的法兰，从而防止软管接头被拉动并且所述支承表面和/或所述软管接头法兰围绕所述软管接头以环形形式围绕所述软管接头的纵向轴线相对于彼此旋转。

9. 发明授权

US4613074A Process for controlling a high-pressure cleaner and high-pressure cleaner for implementing said process 失效
标题翻译：用于控制用于实施所述方法的高压清洁器和高压清洁器的方法
公开(公告)号：US4613074A
公开(公告)日：1986-09-23
申请号：US592405
申请日：1984-03-22
申请人： Werner Schulze
发明人： Werner Schulze
IPC分类号： B05B7/02 , B05B9/01 , B05B9/03 , B08B3/02
CPC分类号： B05B12/002 , B08B3/026 , B08B3/028 , B08B2203/0282 , Y10T137/0379 , Y10T137/8326
摘要： In a high-pressure cleaner, in order to control additional equipment, such as chemical doser or burner, from a hand spray gun without any special control lines, it is proposed to connect a second closable flow path in parallel with the normal flow path through the spray nozzle, to determine the pressure rise time in the cleaning fluid after the switching on of the high-pressure pump and to generate a control signal by opening the second flow path to extend said rise time compared with the rise time when the second flow path is closed; furthermore, a high-pressure cleaner is proposed for implementing this process.
摘要翻译：在高压清洁器中，为了从没有任何特殊控制线的手动喷枪控制诸如化学加药器或燃烧器的附加设备，建议将第二可闭合流动路径与正常流动路径并行连接喷嘴，以确定在高压泵接通之后清洗流体中的压力上升时间，并且通过打开第二流动路径来产生控制信号，以便在第二流动时与上升时间相比延长所述上升时间路径关闭; 此外，提出了一种用于实施该过程的高压清洁器。

10. 发明申请

US20080236300A1 NICKEL ALLOY PRECISION FORCE TRANSDUCER WITH STRAIN GAUGE ELEMENTS 有权
标题翻译：镍合金精密力传感器与应变计量元件
公开(公告)号：US20080236300A1
公开(公告)日：2008-10-02
申请号：US12137983
申请日：2008-06-12
申请人： Tanja MUECK , Volker Relling , Werner Schulze , Michael Steps , Helga Covic
发明人： Tanja MUECK , Volker Relling , Werner Schulze , Michael Steps , Helga Covic
IPC分类号： G01L1/22
CPC分类号： G01L1/2243 , G01B7/20 , G01G3/1414 , G01L1/2287
摘要： A precision force transducer having a spring element (1) whose load-dependent deflection is converted into an electrical signal by means of strain gauge elements (10). The spring element (1) is made of a precipitation-hardenable nickel-based alloy with a nickel content in the range of 36 to 60 percent and a chromium content in the range of 15 to 25 percent. The strain gauge elements (10) are composed of a polymer-free layered film system. This makes it possible to produce a precision force transducer that features great accuracy, low creep and low moisture sensitivity.
摘要翻译：具有弹簧元件（1）的精密力传感器，其弹性元件（1）通过应变仪元件（10）将负载相关的偏转转换成电信号。弹簧元件（1）由镍含量在36％至60％范围内且铬含量在15％至25％范围内的可沉淀硬化的镍基合金制成。应变计元件（10）由无聚合物层状膜系统组成。这使得可以生产具有高精度，低蠕变和低湿度灵敏度的精密力传感器。

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