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1. 发明授权

US10588744B2 Delivery system for prosthetic heart valve 有权
公开(公告)号：US10588744B2
公开(公告)日：2020-03-17
申请号：US15252110
申请日：2016-08-30
申请人： Edwards Lifesciences Corporation
发明人： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
IPC分类号： A61F2/24 , A61F2/95 , A61M25/01
摘要： A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.

2. 发明授权

US11998448B2 Intravascular introducer devices 有权
公开(公告)号：US11998448B2
公开(公告)日：2024-06-04
申请号：US17479225
申请日：2021-09-20
申请人： Edwards Lifesciences Corporation
发明人： Brian C. Gray , Tung T. Le , Andrew Oien , Sonny Tran , Thanh Huy Le , Robert Bowes , Maria L. Saravia , Uy D. Trinh , Hamid Rafi , Alejandro J. Froimovich Rosenberg
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2436 , A61F2/9517
摘要： Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

3. 发明授权

US11707357B2 Delivery system for prosthetic heart valve 有权
公开(公告)号：US11707357B2
公开(公告)日：2023-07-25
申请号：US16820499
申请日：2020-03-16
申请人： Edwards Lifesciences Corporation
发明人： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
IPC分类号： A61F2/24 , A61M25/01 , A61F2/95
CPC分类号： A61F2/2433 , A61F2/2418 , A61F2/2436 , A61F2/9517 , A61M25/0136
摘要： A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.

4. 发明授权

US11123188B2 Intravascular introducer devices 有权
公开(公告)号：US11123188B2
公开(公告)日：2021-09-21
申请号：US16208457
申请日：2018-12-03
申请人： Edwards Lifesciences Corporation
发明人： Brian C. Gray , Tung T. Le , Andrew Oien , Sonny Tran , Thanh Huy Le , Robert Bowes , Maria L. Saravia , Uy D. Trinh , Hamid Rafi , Alejandro J. Froimovich Rosenberg
IPC分类号： A61F2/24 , A61F2/95
摘要： Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

5. 发明申请

US20170065415A1 DELIVERY SYSTEM FOR PROSTHETIC HEART VALVE 审中-公开
标题翻译：用于前置心脏瓣膜的输送系统
公开(公告)号：US20170065415A1
公开(公告)日：2017-03-09
申请号：US15252110
申请日：2016-08-30
申请人： Edwards Lifesciences Corporation
发明人： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
IPC分类号： A61F2/24
摘要： A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.
摘要翻译：用于将可径向压缩和可扩张的假体心脏瓣膜植入心脏的天然心脏瓣膜的输送装置包括手柄部分和从手柄部分延伸并可相对于手柄部分移动的细长轴。轴包括联接到手柄部分的近端部分和构造成将假体心脏瓣膜安装在径向压缩状态的远端部分。手柄部分包括可相对于把手部分纵向移动的控制构件，控制构件接合齿轮组件，该齿轮组件可操作以将控制构件的纵向运动转换为齿轮组件的旋转运动。齿轮组件接合细长轴，使得齿轮组件的旋转运动引起细长轴相对于把手部分的相应纵向运动。

6. 发明公开

US20230301783A1 DELIVERY SYSTEM FOR PROSTHETIC HEART VALVE 审中-公开
公开(公告)号：US20230301783A1
公开(公告)日：2023-09-28
申请号：US18206013
申请日：2023-06-05
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
IPC分类号： A61F2/24
CPC分类号： A61F2/2433 , A61F2/2418 , A61M25/0136
摘要： A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and a balloon catheter assembly comprising an elongated balloon catheter shaft extending from the handle portion. The balloon catheter shaft includes a proximal end portion coupled to the handle portion and a distal end portion. The balloon catheter assembly further includes a balloon coupled to the distal end portion and configured to mount a prosthetic heart valve in a radially compressed state. A protective cover encapsulates the balloon, the cover defining a cavity shaped to accommodate the balloon.

7. 发明申请

US20220000618A1 INTRAVASCULAR INTRODUCER DEVICES 有权
公开(公告)号：US20220000618A1
公开(公告)日：2022-01-06
申请号：US17479225
申请日：2021-09-20
申请人： Edwards Lifesciences Corporation
发明人： Brian C. Gray , Tung T. Le , Andrew Oien , Sonny Tran , Thanh Huy Le , Robert Bowes , Maria L. Saravia , Uy D. Trinh , Hamid Rafi , Alejandro J. Froimovich Rosenberg
IPC分类号： A61F2/24
摘要： Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

8. 发明授权

US10154904B2 Intravascular introducer devices 有权
公开(公告)号：US10154904B2
公开(公告)日：2018-12-18
申请号：US14695607
申请日：2015-04-24
申请人： Edwards Lifesciences Corporation
发明人： Brian C. Gray , Tung T. Le , Andrew Oien , Sonny Tran , Thanh Huy Le , Robert Bowes , Maria L. Saravia , Uy D. Trinh , Hamid Rafi , Alejandro J. Froimovich Rosenberg
IPC分类号： A61F2/24 , A61F2/962 , A61F2/95
摘要： Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

9. 发明申请

US20150305863A1 INTRAVASCULAR INTRODUCER DEVICES 审中-公开
标题翻译：血管内引导装置
公开(公告)号：US20150305863A1
公开(公告)日：2015-10-29
申请号：US14695607
申请日：2015-04-24
申请人： Edwards Lifesciences Corporation
发明人： Brian C. Gray , Tung T. Le , Andrew Oien , Sonny Tran , Thanh Huy Le , Robert Bowes , Maria L. Saravia , Uy D. Trinh , Hamid Rafi , Alejandro J. Froimovich Rosenberg
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/962 , A61F2002/9517
摘要： Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.
摘要翻译：导引器装置的公开的实施例提供止血密封，并且允许输送导管插入通过导引器密封件，而不使用覆盖安装在导管上的医疗装置的单独的装载器装置。一些公开的导引器包括壳体，远端护套，其从壳体向远侧延伸并适于插入患者的脉管系统中，安装在壳体内的远端止血密封件和安装在壳体内的近端止血密封件，以及位于壳体内部的可滑动管壳体，其相对于近端位置和远端位置之间的远端止血密封件纵向移动，其中在近侧位置，所述管的远端位于所述远端止血密封件的近侧，所述远端止血密封件封闭，并且其中远端位置，管的远端延伸穿过远端止血密封。

10. 发明公开

US20240277474A1 INTRAVASCULAR INTRODUCER DEVICES 审中-公开
公开(公告)号：US20240277474A1
公开(公告)日：2024-08-22
申请号：US18651890
申请日：2024-05-01
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： Brian C. Gray , Tung T. Le , Andrew Oien , Sonny Tran , Thanh Huy Le , Robert Bowes , Maria L. Saravia , Uy D. Trinh , Hamid Rafi , Alejandro J. Froimovich Rosenberg
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2436 , A61F2/9517
摘要： Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

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