专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050019810A1 Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic and other uses 审中-公开
标题翻译：编码具有预后，诊断，预防，治疗和其他用途的蛋白质的新型基因
公开(公告)号：US20050019810A1
公开(公告)日：2005-01-27
申请号：US10900926
申请日：2004-07-28
申请人： Douglas Holtzman , Andrew Goodearl , Sean McCarthy
发明人： Douglas Holtzman , Andrew Goodearl , Sean McCarthy
IPC分类号： A61K38/00 , C07K14/47 , C07K14/705 , C07K14/715 , C12Q1/68 , G01N33/68 , C07H21/04
CPC分类号： C07K14/705 , A61K38/00 , C07K14/47 , C07K14/7151 , C07K2319/00 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , G01N33/6872
摘要： The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods using compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.
摘要翻译：本发明提供编码具有诊断，预防，治疗和其它用途的各种蛋白质的分离的核酸。这些核酸和蛋白质可用于诊断，预防和治疗许多人类和其他动物疾病。本发明还提供反义核酸分子，含有本发明的核酸分子的表达载体，已经引入了表达载体的宿主细胞和其中引入了本发明的核酸分子的非人转基因动物，或中断了本发明还进一步提供分离的多肽，融合多肽，抗原肽和抗体。还提供了使用本发明组合物的诊断，筛选和治疗方法。本发明的核酸和多肽可用作调节各种细胞过程的调节剂。

2. 发明申请

US20070048771A1 Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses 失效
标题翻译：编码具有预后，诊断，预防，治疗和其他用途的蛋白质的新基因
公开(公告)号：US20070048771A1
公开(公告)日：2007-03-01
申请号：US11491318
申请日：2006-07-21
申请人： Sean McCarthy , Christopher Fraser , John Sharp , Thomas Barnes , Susan Kirst , Paul Myers , Nicholas Wrighton , Andrew Goodearl , Douglas Holtzman , Mehran Khodadoust
发明人： Sean McCarthy , Christopher Fraser , John Sharp , Thomas Barnes , Susan Kirst , Paul Myers , Nicholas Wrighton , Andrew Goodearl , Douglas Holtzman , Mehran Khodadoust
IPC分类号： C12Q1/68 , G01N33/53 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/47
摘要： The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods using compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.
摘要翻译：本发明提供编码具有诊断，预防，治疗和其它用途的各种蛋白质的分离的核酸。这些核酸和蛋白质可用于诊断，预防和治疗许多人类和其他动物疾病。本发明还提供反义核酸分子，含有本发明的核酸分子的表达载体，已经引入了表达载体的宿主细胞和其中引入了本发明的核酸分子的非人转基因动物，或中断了本发明还进一步提供分离的多肽，融合多肽，抗原肽和抗体。还提供了使用本发明组合物的诊断，筛选和治疗方法。本发明的核酸和多肽可用作调节各种细胞过程的调节剂。

3. 发明申请

US20060211848A1 Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic and other uses 审中-公开
公开(公告)号：US20060211848A1
公开(公告)日：2006-09-21
申请号：US11441587
申请日：2006-05-26
申请人： Douglas Holtzman , Andrew Goodearl , Sean McCarthy
发明人： Douglas Holtzman , Andrew Goodearl , Sean McCarthy
IPC分类号： C07K14/705 , C07H21/04 , C12P21/06
CPC分类号： C12N9/6489 , A01K2217/05 , A01K2227/105 , A61K38/00 , C07K14/47 , C07K14/705 , C07K14/70578 , C07K2319/00
摘要： The invention relates to Tango-73, Tango-74, Tango-76, Tango-78, and Tango-83 polypeptides, nucleic acid molecules encoding Tango-73, Tango-74, Tango-76, Tango-78, and Tango-83, and uses thereof. The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods using compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.

4. 发明申请

US20060205034A1 Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses 审中-公开
公开(公告)号：US20060205034A1
公开(公告)日：2006-09-14
申请号：US11265762
申请日：2005-11-02
申请人： Christopher Fraser , Sean McCarthy , John Sharp , Thomas Barnes , Nicholas Wrighton , Charles Mackay , Kevin Leiby , Douglas Holtzman
发明人： Christopher Fraser , Sean McCarthy , John Sharp , Thomas Barnes , Nicholas Wrighton , Charles Mackay , Kevin Leiby , Douglas Holtzman
IPC分类号： C07K14/715 , C07H21/04 , C12P21/06 , C07K16/28
CPC分类号： C07K16/18
摘要： The invention provides isolated nucleic acid molecules and polypeptide molecules. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

5. 发明申请

US20060122373A1 Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof 审中-公开
标题翻译： Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和整合素α亚基蛋白和核酸分子及其用途
公开(公告)号：US20060122373A1
公开(公告)日：2006-06-08
申请号：US11175714
申请日：2005-07-05
申请人： Sean McCarthy , David Gearing , Douglas Holtzman , Yang Pan , Samantha Busfield , Thomas Barnes , Charles Mackay , Jose Lora
发明人： Sean McCarthy , David Gearing , Douglas Holtzman , Yang Pan , Samantha Busfield , Thomas Barnes , Charles Mackay , Jose Lora
IPC分类号： C07K14/705 , C07K14/715 , C07H21/04 , C12P21/06
CPC分类号： C12Q1/48 , A61K38/00 , C07K14/47 , C07K2319/00 , C12Q1/6876
摘要： The invention provides novel Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 polypeptides, proteins, and nucleic acid molecules. In addition to isolated, full-length Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 proteins, the invention further provides isolated Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 fusion proteins, antigenic peptides and anti-Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 antibodies. The invention also provides Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 and A259 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a Delta3, FTHMA-070, Tango85, Tango77, SPOIL, NEOKINE, Tango129 or A259 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供新颖的Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259多肽，蛋白质和核酸分子。除了分离的全长Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259蛋白外，本发明还提供了分离的Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259融合蛋白质，抗原肽和抗Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259抗体。本发明还提供了Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129和A259核酸分子，含有本发明的核酸分子的重组表达载体，已经引入了表达载体的宿主细胞，已经引入或破坏了Delta3，FTHMA-070，Tango85，Tango77，SPOIL，NEOKINE，Tango129或A259基因的人类转基因动物。还提供利用本发明组合物的诊断，筛选和治疗方法。

6. 发明申请

US20050032172A1 Novel molecules of the FTHMA-070-related protein family and the T85-related protein family and uses thereof 审中-公开
标题翻译： FTHMA-070相关蛋白家族和T85相关蛋白家族的新分子及其用途
公开(公告)号：US20050032172A1
公开(公告)日：2005-02-10
申请号：US10895676
申请日：2004-07-21
申请人： Sean McCarthy , Douglas Holtzman
发明人： Sean McCarthy , Douglas Holtzman
IPC分类号： G01N33/53 , C07K14/705 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/566 , C07K14/52 , C07H21/04
CPC分类号： C07K14/70503 , C07K14/70578
摘要： Novel FTHMA-070 and T85 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length FTHMA-070 and T85 proteins, the invention further provides isolated FTHMA-070 and T85 fusion proteins, antigenic peptides and anti-FTHMA-070 and anti-T85 antibodies. The invention also provides FTHMA-070 and T85 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a FTHMA-070 gene or T85 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：公开了新的FTHMA-070和T85多肽，蛋白质和核酸分子。除了分离的全长FTHMA-070和T85蛋白之外，本发明还提供了分离的FTHMA-070和T85融合蛋白，抗原肽和抗FTHMA-070和抗T85抗体。本发明还提供了FTHMA-070和T85核酸分子，含有本发明的核酸分子的重组表达载体，已经引入了表达载体的宿主细胞和其中FTHMA-070基因或T85的非人转基因动物基因已被引入或破坏。还提供利用本发明组合物的诊断，筛选和治疗方法。

7. 发明申请

US20110001379A1 PASSIVE MAGNETIC BEARING 审中-公开
标题翻译：被动磁性轴承
公开(公告)号：US20110001379A1
公开(公告)日：2011-01-06
申请号：US12829457
申请日：2010-07-02
申请人： Sean McCarthy , Seamus Flanagan , Alan Simpson , Maxime Sorin
发明人： Sean McCarthy , Seamus Flanagan , Alan Simpson , Maxime Sorin
IPC分类号： H02K7/09
CPC分类号： F16C32/0425 , F16C19/10 , F16C32/0402
摘要： A passive magnetic bearing which has an exceptionally low friction couple. Radial and axial restraint is achieved through magnetic and mechanical means. The embodiment of the passive magnetic bearing has two axially magnetized rings, which each exhibit at least one pair of north and south poles. The magnetized rings are positioned in a manner where the poles are in a repulsive magnetic interaction such that the plane of symmetry which separates the like poles lies perpendicular to the axis of the rotation of a shaft and this radially constrains the movement of the shaft. Axial rigidity is added to the system by the use of ceramic bearings and related axial retaining mechanisms on one of the ring magnets thus maintaining the magnetic bearing in an otherwise unstable axial plane.
摘要翻译：一种具有极低摩擦力的无源磁轴承。通过磁力和机械方式实现径向和轴向约束。无源磁轴承的实施例具有两个轴向磁化的环，每个环表现出至少一对北极和南极。磁化环以这样的方式定位，其中磁极处于排斥磁相互作用，使得分离相同磁极的对称平面垂直于轴的旋转轴线，并且这径向地限制轴的运动。通过在其中一个环形磁体上使用陶瓷轴承和相关的轴向保持机构将轴向刚度加到系统上，从而将磁轴承保持在另外不稳定的轴向平面。

8. 发明申请

US20060227993A1 Method and apparatus for determining if an optical disk originated from a valid source 失效
标题翻译：用于确定光盘是否源自有效源的方法和装置
公开(公告)号：US20060227993A1
公开(公告)日：2006-10-12
申请号：US11352608
申请日：2006-02-13
申请人： Phelim O'Doherty , Patrick Smith , Carlos Luna , Sean McCarthy
发明人： Phelim O'Doherty , Patrick Smith , Carlos Luna , Sean McCarthy
IPC分类号： G06K9/00
CPC分类号： G01N21/9506 , G06K9/00577 , G06K9/2036 , G11B20/00086 , G11B20/0013 , G11B20/00173 , G11B23/284
摘要： A method and apparatus for determining if an optical disk originated from a valid source, the method and apparatus scanning one major surface of the optical disk for mechanical surface imperfections, storing the locations of the surface imperfections relative to a datum, comparing a parameter of each of the locations of the surface imperfections with corresponding parameters of a master disk of known source for determining if the disk originated from the source from which the master disk originated.
摘要翻译：一种用于确定光盘是否源自有效源的方法和装置，所述方法和装置扫描光盘的一个主表面用于机械表面缺陷，存储表面缺陷相对于基准的位置，比较每个表面缺陷的位置与已知源的主盘的相应参数相关联，以确定磁盘是否源自主盘的源。

9. 发明申请

US20050164393A1 Method for identifying genes encoding signal sequences 审中-公开
标题翻译：识别编码信号序列的基因的方法
公开(公告)号：US20050164393A1
公开(公告)日：2005-07-28
申请号：US11048658
申请日：2005-01-25
申请人： Sean McCarthy , Steven Bossone
发明人： Sean McCarthy , Steven Bossone
IPC分类号： C12N1/19 , C12N15/10 , C12N15/81 , C12Q1/68 , C12N1/18 , C12N15/74
CPC分类号： C12Q1/6897 , C12N15/1034 , C12N15/1051 , C12N15/81
摘要： The invention involves a method of identifying nucleic acid sequences encoding signal peptide-containing proteins. The method features chimeric constructs containing a KRE9 gene that lacks a signal sequence. Yeast containing chimeric KRE9 plasmid constructs that encode signal sequences are selected based on their ability to grow on media in which sucrose is the sole carbon source.
摘要翻译：本发明涉及鉴定编码含有信号肽的蛋白质的核酸序列的方法。该方法具有含有缺少信号序列的KRE9基因的嵌合构建体。基于它们在其中蔗糖是唯一碳源的培养基上生长的能力来选择含有编码信号序列的嵌合KRE9质粒构建体的酵母。

10. 发明授权

US08098924B2 Method and apparatus for determining if an optical disk originated from a valid source 失效
标题翻译：用于确定光盘是否源自有效源的方法和装置
公开(公告)号：US08098924B2
公开(公告)日：2012-01-17
申请号：US12108180
申请日：2008-04-23
申请人： Patrick Smith , Phelim O'Doherty , Sean McCarthy
发明人： Patrick Smith , Phelim O'Doherty , Sean McCarthy
IPC分类号： G06K9/00 , G01N21/00
CPC分类号： G11B23/281 , G11B5/865 , G11B7/263 , G11B20/00086
摘要： A method and apparatus for determining if an optical disk originated from a valid source, the method and apparatus scanning one major surface of the optical disk for imperfections, storing the locations of the imperfections relative to a datum, comparing a parameter of each of the locations of the imperfections with corresponding parameters of a master disk of known source for determining if the disk originated from the source from which the master disk originated.
摘要翻译：一种用于确定光盘是否源自有效源的方法和装置，所述方法和装置扫描光盘的一个主表面以获得缺陷，存储缺陷相对于基准的位置，比较每个位置的参数具有已知源的主盘的相应参数的缺陷，用于确定盘是否源自主盘的源。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式