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1. 发明授权

US07759408B2 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups 有权
标题翻译：用可聚合的阳离子亲水基团封端的含硅单体
公开(公告)号：US07759408B2
公开(公告)日：2010-07-20
申请号：US11341209
申请日：2006-01-27
申请人： Derek Schorzman , Joseph C. Salamone , Jay Kunzler , Jeffrey G. Linhardt
发明人： Derek Schorzman , Joseph C. Salamone , Jay Kunzler , Jeffrey G. Linhardt
IPC分类号： G02B1/04 , C08F290/06
CPC分类号： G02B1/043 , A61L27/18 , C08F222/1006 , C08F230/08 , C08F290/06 , C08F290/061 , C08F290/068 , C08G77/388 , C08L51/085 , C08L101/02 , C08L83/04
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups.
摘要翻译：本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。更具体地，本发明涉及能聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些阳离子单体。这些性质包括用水提取聚合的医疗装置的能力。这避免了使用本领域典型的有机溶剂。聚合物组合物包含聚合的含有可聚合阳离子亲水基团的含硅单体。

2. 发明授权

US07622512B2 Cationic hydrophilic siloxanyl monomers 有权
标题翻译：阳离子亲水硅氧烷基单体
公开(公告)号：US07622512B2
公开(公告)日：2009-11-24
申请号：US11341208
申请日：2006-01-27
申请人： Derek Schorzman , Joseph C. Salamone , Daniel Ammon , Jay Kunzler , Jeffrey G. Linhardt
发明人： Derek Schorzman , Joseph C. Salamone , Daniel Ammon , Jay Kunzler , Jeffrey G. Linhardt
IPC分类号： G02B1/04 , C08F290/06
CPC分类号： C08F230/08 , C08F226/10
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers.
摘要翻译：本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。更具体地，本发明涉及能聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些阳离子单体。这些性质包括用水提取聚合的医疗装置的能力。这避免了使用本领域典型的有机溶剂。聚合物组合物包含聚合的阳离子亲水硅氧烷基单体。

3. 发明授权

US07557231B2 Carboxylic tris-like siloxanyl monomers 有权
标题翻译：羧酸类三硅氧烷基单体
公开(公告)号：US07557231B2
公开(公告)日：2009-07-07
申请号：US11480053
申请日：2006-06-30
申请人： Derek Schorzman , Jay Kunzler , Joseph C. Salamone
发明人： Derek Schorzman , Jay Kunzler , Joseph C. Salamone
IPC分类号： C07F7/08
CPC分类号： C07F7/0838
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerized carboxylic hydrophilic siloxanyl monomers.
摘要翻译：本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。更具体地说，本发明涉及能够聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些羧酸单体。聚合物组合物包含聚合的羧酸亲水硅氧烷基单体。

4. 发明申请

US20080000201A1 Carboxylic tris-like siloxanyl monomers 有权
标题翻译：羧酸类三硅氧烷基单体
公开(公告)号：US20080000201A1
公开(公告)日：2008-01-03
申请号：US11480053
申请日：2006-06-30
申请人： Derek Schorzman , Jay Kunzler , Joseph C. Salamone
发明人： Derek Schorzman , Jay Kunzler , Joseph C. Salamone
IPC分类号： B65B55/02 , C08F2/00 , C08G77/04 , C08G77/26 , C08F6/00
CPC分类号： C07F7/0838
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerized carboxylic hydrophilic siloxanyl monomers.
摘要翻译：本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。更具体地说，本发明涉及能够聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些羧酸单体。聚合物组合物包含聚合的羧酸亲水硅氧烷基单体。

5. 发明申请

US20080004413A1 Carboxylic M2Dx-like siloxanyl monomers 审中-公开
标题翻译：羧酸M2Dx样硅氧烷基单体
公开(公告)号：US20080004413A1
公开(公告)日：2008-01-03
申请号：US11480111
申请日：2006-06-30
申请人： Derek Schorzman , Jay Kunzler , Joseph C. Salamone
发明人： Derek Schorzman , Jay Kunzler , Joseph C. Salamone
IPC分类号： C08G77/04 , C08L83/04
CPC分类号： C08G77/38 , A61L27/18 , C08G77/388 , C08L83/06 , C08L83/04
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain carboxylic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerized carboxylic hydrophilic siloxanyl monomers.
摘要翻译：本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。更具体地说，本发明涉及能够聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些羧酸单体。聚合物组合物包含聚合的羧酸亲水硅氧烷基单体。

6. 发明授权

US07544751B2 Polymerization products and biomedical devices containing same 失效
标题翻译：聚合产物和含有其的生物医学装置
公开(公告)号：US07544751B2
公开(公告)日：2009-06-09
申请号：US12181018
申请日：2008-07-28
申请人： Derek Schorzman , Joseph C. Salamone
发明人： Derek Schorzman , Joseph C. Salamone
IPC分类号： C08F114/18
CPC分类号： C08G77/385 , C08F214/18 , C08F290/062 , C08F290/068 , G02B1/043 , C08L27/12
摘要： Polymerization products formed from a monomeric mixture comprising (a) one or more first monomers of the general formula I: A-L-R1—(X—CF═CF2)n (I) wherein R1 represents one or more inertly substituted groups; X is independently a group which links the inertly substituted groups and the trifluorovinyl group; L is an optional linking group; A is CO2Z, SO2Z, PO3Z, or OPO3Z wherein Z is hydrogen or an alkali metal and n is an integer of 1 to about 1000; (b) one or more second crosslinking monomers comprising at least three trifluorovinyl groups and (c) one or more prepolymers comprising one or more trifluorovinyl groups are provided. Also provided are biomedical devices formed from such polymerization products.
摘要翻译：由单体混合物形成的聚合产物包含（a）一种或多种通式I的第一单体：<？in-line-formula description =“In-line formula”end =“lead”→> AL-R1-（X -CF-CF 2）n（I）<？in-line-formula description =“In-line Formulas”end =“tail”？>其中R1表示一个或多个惰性取代基团; X独立地是连接惰性取代基和三氟乙烯基的基团; L是可选的连接基团; A是CO 2 Z，SO 2 Z，PO 3 Z或OPO 3 Z，其中Z是氢或碱金属，n是1至约1000的整数; （b）提供包含至少三个三氟乙烯基的一种或多种第二交联单体和（c）一种或多种包含一个或多个三氟乙烯基的预聚物。还提供了由这种聚合产物形成的生物医学装置。

7. 发明授权

US07538160B2 Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers 失效
标题翻译：含三氟乙烯基芳族化合物的聚（烷基醚）预聚物
公开(公告)号：US07538160B2
公开(公告)日：2009-05-26
申请号：US11173705
申请日：2005-07-01
申请人： Derek Schorzman , Joseph C. Salamone
发明人： Derek Schorzman , Joseph C. Salamone
IPC分类号： C08F114/18
CPC分类号： C08G65/337
摘要： The present invention provides prepolymers based on poly(alkyl ethers) having terminal triflurovinyl aromatic containing groups and polymers produced from such polymers. The prepolymers and polymers are useful as biomedical devices such as contact lenses or intraocular lenses.
摘要翻译：本发明提供了基于具有末端三氟乙烯基芳族化合物基团的聚（烷基醚）和由这些聚合物制备的聚合物的预聚物。预聚物和聚合物可用作生物医学装置如隐形眼镜或人工晶状体。

8. 发明授权

US07534836B2 Biomedical devices 失效
标题翻译：生物医学装置
公开(公告)号：US07534836B2
公开(公告)日：2009-05-19
申请号：US11173698
申请日：2005-07-01
申请人： Derek Schorzman , Joseph C. Salamone
发明人： Derek Schorzman , Joseph C. Salamone
IPC分类号： C08F114/18
CPC分类号： G02B1/043 , A61L27/16 , C08L27/12
摘要： Biomedical devices are provided herein which are formed from a polymerization product of a monomeric mixture comprising one or more monomers comprising one or more trifluorovinyl groups, e.g., a perfluorocyclobutane containing polymer.
摘要翻译：本文提供了生物医学装置，其由包含一种或多种包含一个或多个三氟乙烯基的单体的单体混合物的聚合产物形成，例如含全氟环丁烷的聚合物。

9. 发明申请

US20080287626A1 Polymerization Products and Biomedical Devices Containing Same 失效
标题翻译：聚合产物和含有其的生物医学装置
公开(公告)号：US20080287626A1
公开(公告)日：2008-11-20
申请号：US12181018
申请日：2008-07-28
申请人： Derek Schorzman , Joseph C. Salamone
发明人： Derek Schorzman , Joseph C. Salamone
IPC分类号： C08F114/18
CPC分类号： C08G77/385 , C08F214/18 , C08F290/062 , C08F290/068 , G02B1/043 , C08L27/12
摘要： Polymerization products formed from a monomeric mixture comprising (a) one or more first monomers of the general formula I: A-L-R1—(X—CF═CF2)n (I) wherein R1 represents one or more inertly substituted groups; X is independently a group which links the inertly substituted groups and the trifluorovinyl group; L is an optional linking group; A is CO2Z, SO2Z, PO3Z, or OPO3Z wherein Z is hydrogen or an alkali metal and n is an integer of 1 to about 1000; (b) one or more second crosslinking monomers comprising at least three trifluorovinyl groups and (c) one or more prepolymers comprising one or more trifluorovinyl groups are provided. Also provided are biomedical devices formed from such polymerization products.
摘要翻译：由单体混合物形成的聚合产物包含（a）一种或多种通式I的第一单体：<？in-line-formula description =“In-line formula”end =“lead”→> ALR < /（X-CF-CF 2）N（I）<？in-line-formula description =“In-line Formulas”end =“tail” 其中R 1表示一个或多个惰性取代基团; X独立地是连接惰性取代基和三氟乙烯基的基团; L是可选的连接基团; A是CO 2 Z，SO 2 Z，PO 3 Z或OPO 3 Z其中Z是氢或碱金属，n为1〜1000的整数，（b）提供包含至少三个三氟乙烯基的一种或多种第二交联单体和（c）一种或多种包含一个或多个三氟乙烯基的预聚物。还提供了由这种聚合产物形成的生物医学装置。

10. 发明授权

US07425600B2 Polymerization products and biomedical devices containing same 失效
标题翻译：聚合产物和含有其的生物医学装置
公开(公告)号：US07425600B2
公开(公告)日：2008-09-16
申请号：US11174020
申请日：2005-07-01
申请人： Derek Schorzman , Joseph C. Salamone
发明人： Derek Schorzman , Joseph C. Salamone
IPC分类号： C08F114/18
CPC分类号： C08G77/385 , C08F214/18 , C08F290/062 , C08F290/068 , G02B1/043 , C08L27/12
摘要： Polymerization products formed from a monomeric mixture comprising (a) one or more first monomers of the general formula I: A-L-R1—(X—CF═CF2)n (I) wherein R1 represents one or more inertly substituted groups; X is independently a group which links the inertly substituted groups and the trifluorovinyl group; L is an optional linking group; A is CO2Z, SO2Z, PO3Z, or OPO3Z wherein Z is hydrogen or an alkali metal and n is an integer of 1 to about 1000; (b) one or more second crosslinking monomers comprising at least three trifluorovinyl groups and (c) one or more prepolymers comprising one or more trifluorovinyl groups are provided. Also provided are biomedical devices formed from such polymerization products.
摘要翻译：由单体混合物形成的聚合产物包含（a）一种或多种通式I的第一单体：<？in-line-formula description =“In-line formula”end =“lead”→> ALR < /（X-CF-CF 2）N（I）<？in-line-formula description =“In-line Formulas”end =“tail” 其中R 1表示一个或多个惰性取代基团; X独立地是连接惰性取代基和三氟乙烯基的基团; L是可选的连接基团; A是CO 2 Z，SO 2 Z，PO 3 Z或OPO 3 Z其中Z是氢或碱金属，n为1〜1000的整数，（b）提供包含至少三个三氟乙烯基的一种或多种第二交联单体和（c）一种或多种包含一个或多个三氟乙烯基的预聚物。还提供了由这种聚合产物形成的生物医学装置。

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