专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06429194B1 Mucin containing ophthalmic preparation 失效
标题翻译：粘蛋白含眼用制剂
公开(公告)号：US06429194B1
公开(公告)日：2002-08-06
申请号：US09888144
申请日：2001-06-22
申请人： Charles D. Leahy , Edward J. Ellis , Jeanne Y. Ellis
发明人： Charles D. Leahy , Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： A61K3816
CPC分类号： A61K9/0048 , A61K38/1709 , Y10S514/912
摘要： Aqueous ophthalmic preparations are provided and are intended to be instilled into the eye, or in which to pre soak or store an object to be inserted into the eye, such as a contact lens, an ointment, or a solid device to be inserted into the conjunctival sac. The preparations disclosed are utilized for the treatment of a tear film and ocular surface disorder known as keratoconjunctivitis sicca or dry eye syndrome. In general, the preparations of this invention are also effective for the relief of symptoms of eye irritation, such as those caused by dry environmental conditions or by contact lens wear. In accordance with the present invention, the ophthalmic preparation includes a mucin component, similar to that found at the normal human ocular surface and in one exemplary and preferred embodiment, the mucin is a transmembrane or surface mucin.
摘要翻译：提供水性眼用制剂，其目的是滴入眼中，或预先浸泡或储存待插入眼睛的物体，例如隐形眼镜，软膏或固体装置以插入到眼睛中结膜囊所公开的制剂用于治疗称为角结膜炎或干眼综合征的泪膜和眼表疾病。通常，本发明的制剂对于缓解眼睛刺激症状（例如由干燥环境条件引起的或由隐形眼镜磨损引起的）的症状也是有效的。根据本发明，眼用制剂包括与普通人眼表面相似的粘蛋白组分，在一个示例性和优选的实施方案中，粘蛋白是跨膜或表面粘蛋白。

2. 发明授权

US06281192B1 Mucin containing ophthalmic preparations 失效
标题翻译：粘蛋白含眼用制剂
公开(公告)号：US06281192B1
公开(公告)日：2001-08-28
申请号：US09516671
申请日：2000-03-01
申请人： Charles D. Leahy , Edward J. Ellis , Jeanne Y. Ellis
发明人： Charles D. Leahy , Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： A61K3816
CPC分类号： A61K9/0048 , A61K38/1709 , Y10S514/912
摘要： The present invention discloses the ophthalmic applications of mucin derived from mammalian milk or milk byproducts. This mucin has been found to be a MUC1 type mucin similar to the transmembrane mucin expressed on the surface of the human eye. The mucin-containing preparations described in this invention can be in the form of an aqueous formulation to be instilled into the eye, or in which to pre-soak or store an object to be inserted into the eye, such as a contact lens, an ointment, or a solid device to be inserted into the conjunctival sac. The preparations disclosed are utilized for the treatment of tear film and ocular surface disorders associated with the signs and symptoms of dry eye. Furthermore, mucin-based formulations are also effective for the relief of symptoms of eye irritation, such as those caused by environmental conditions or by contact lens wear.
摘要翻译：本发明公开了衍生自哺乳动物乳或乳副产物的粘蛋白的眼科应用。已发现这种粘蛋白是类似于在人眼表面上表达的跨膜粘蛋白的MUC1型粘蛋白。本发明中描述的含粘蛋白的制剂可以是要滴入眼中的水性制剂的形式，或其中预先浸泡或储存待插入眼睛的物体，例如隐形眼镜，软膏，或插入结膜囊的固体装置。所公开的制剂用于治疗与干眼症状和症状相关的泪液和眼表疾病。此外，基于粘蛋白的制剂也有助于缓解眼睛刺激症状，例如由环境条件引起的或隐形眼镜磨损引起的症状。

3. 发明授权

US06478881B2 Contact lens cleaning solution 失效
标题翻译：隐形眼镜清洁液
公开(公告)号：US06478881B2
公开(公告)日：2002-11-12
申请号：US09795766
申请日：2001-02-28
申请人： Jeanne Y. Ellis , Edward J. Ellis
发明人： Jeanne Y. Ellis , Edward J. Ellis
IPC分类号： A61L218
CPC分类号： C11D3/3765 , C11D3/0078 , C11D3/225 , Y10S514/84
摘要： The present invention is based on the unexpected finding that the combination of a carboxylate containing anionic polymer, of molecular weight greater than about 1000 daltons, with cleaning agents, provides improved contact lens cleaning preparations. The present invention includes contacting a soiled contact lens with an aqueous solution comprising an anionically charged polymer and a surfactant or surfactant combination selected from the classes of nonionic surfactants, anionic surfactants, and amphoteric surfactants.
摘要翻译：本发明基于意想不到的发现，即分子量大于约1000道尔顿的含羧酸盐的阴离子聚合物与清洁剂的组合提供改进的隐形眼镜清洁制剂。本发明包括使污染的隐形眼镜与包含阴离子带电聚合物的水溶液和选自非离子表面活性剂，阴离子表面活性剂和两性表面活性剂的表面活性剂或表面活性剂组合物接触。

4. 发明授权

US4625007A Silicone-containing contact lens material and contact lenses made thereof 失效
标题翻译：含有硅酮的隐形眼镜材料及其制成的隐形眼镜
公开(公告)号：US4625007A
公开(公告)日：1986-11-25
申请号：US692904
申请日：1985-01-18
申请人： Edward J. Ellis , Jeanne Y. Ellis
发明人： Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： C08F283/12 , C08G77/20 , G02B1/04 , C08F30/08
CPC分类号： C08G77/20 , C08F283/124 , G02B1/043
摘要： Multifunctional organopolysiloxane resin systems are provided whose starting materials comprise a reactive vinyl containing silane, a disubstituted silane and a trisubstituted silane hydrolyzed together to form a resin system. The preferred material of the resin system has a viscosity of from 7 to 70 centistokes at 25.degree. C. The preferred material is in the form of a contact lens and also contains an ester and a hydrophilic agent.
摘要翻译：提供了多功能有机聚硅氧烷树脂体系，其起始材料包括反应性含乙烯基硅烷，二取代硅烷和三取代硅烷一起水解以形成树脂体系。树脂体系的优选材料在25℃下的粘度为7至70厘沲。优选的材料为隐形眼镜的形式，并且还含有酯和亲水剂。

5. 发明授权

US5401327A Method of treating contact lenses 失效
标题翻译：治疗隐形眼镜的方法
公开(公告)号：US5401327A
公开(公告)日：1995-03-28
申请号：US80429
申请日：1993-06-18
申请人： Edward J. Ellis , Jeanne Y. Ellis
发明人： Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： A61L12/08 , A61L12/14 , C11D1/58 , C11D1/66 , C11D1/72 , C11D3/00 , C11D3/22 , C11D3/37 , B08B3/04 , B08B3/08
CPC分类号： C11D3/3788 , A61L12/08 , A61L12/141 , A61L12/143 , C11D1/58 , C11D1/662 , C11D1/72 , C11D3/0078 , C11D3/227
摘要： Methods of treating contact lenses employ a material composed of (a) a hydrophobic core having at least three carbon atoms and (b) at least three hydrophilic polyethylene oxide chains attached to the core.
摘要翻译：处理隐形眼镜的方法采用由（a）具有至少三个碳原子的疏水核心组成的材料和（b）至少三个附着在芯上的亲水性聚环氧乙烷链。

6. 发明申请

US20100178315A1 POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY 审中-公开
标题翻译：用于控制药物治疗的聚合体系
公开(公告)号：US20100178315A1
公开(公告)日：2010-07-15
申请号：US12633093
申请日：2009-12-08
申请人： Jeanne Y. Ellis , Edward J. Ellis
发明人： Jeanne Y. Ellis , Edward J. Ellis
IPC分类号： A61K31/5377 , A61F2/00 , A61P27/06
CPC分类号： A61K9/0004 , A61K9/0048 , A61K9/0053 , A61K47/32 , A61K47/34
摘要： Polymeric compositions containing a high percentage of bound alkyl ether segments provide matrices and membranes for the controlled release of drugs and medicinal agents. The polymeric compositions are prepared by the polymerization of ethylenically unsaturated alkyl ether containing monomers. Copolymers of ethylenically unsaturated alkyl ether containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility in the construction of controlled release devices.
摘要翻译：含有高百分比的结合的烷基醚链段的聚合物组合物提供用于药物和药物的受控释放的基质和膜。通过烯键式不饱和烷基醚单体的聚合制备聚合物组合物。还公开了含有烯属不饱和烷基醚的单体与共聚单体的共聚物。本发明的负载药物的聚合物组合物在控制释放装置的构造中特别有用。

7. 发明授权

US5872086A Composition for wetting contact lenses 失效
标题翻译：润湿隐形眼镜的组成
公开(公告)号：US5872086A
公开(公告)日：1999-02-16
申请号：US932394
申请日：1997-09-17
申请人： Edward J. Ellis , Jeanne Y. Ellis
发明人： Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： A61L12/08 , A61L12/14 , C11D1/58 , C11D1/66 , C11D1/72 , C11D3/00 , C11D3/22 , C11D3/37 , C11D10/02
CPC分类号： C11D3/3788 , A61L12/08 , A61L12/141 , A61L12/143 , C11D1/58 , C11D1/662 , C11D1/72 , C11D3/0078 , C11D3/227
摘要： Ophthalmic solutions include a material composed of (a) a hydrophobic core having at least three carbon atoms and (b) at least three hydrophilic polyethylene oxide chains attached to the core.Examples of such materials include ethoxylated derivatives of glucose, glycerin, sorbitol, and divinyl benzene.
摘要翻译：眼科溶液包括由（a）具有至少三个碳原子的疏水性核心组成的材料和（b）至少三个连接到核心上的亲水性聚环氧乙烷链。这些材料的实例包括葡萄糖，甘油，山梨糖醇和二乙烯基苯的乙氧基化衍生物。

8. 发明授权

US5405878A Contact lens solution containing cationic glycoside 失效
标题翻译：含有阳离子糖苷的隐形眼镜溶液
公开(公告)号：US5405878A
公开(公告)日：1995-04-11
申请号：US80423
申请日：1993-06-18
申请人： Edward J. Ellis , Jeanne Y. Ellis
发明人： Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： G02C13/00 , C11D1/62 , C11D3/00 , C11D3/22 , C11D1/83
CPC分类号： C11D3/0078 , C11D3/221 , C11D1/62 , Y10S514/839 , Y10S514/84
摘要： Compositions for treating contact lenses, particularly rigid, gas permeable contact lenses, comprise a quaternary nitrogen-containing ethoxylated alkyl glucoside.
摘要翻译：用于治疗隐形眼镜，特别是刚性的透气隐形眼镜的组合物包含季氮含量的乙氧基化烷基葡糖苷。

9. 发明授权

US09102105B2 Method for forming an ocular drug delivery device 有权
标题翻译：用于形成眼药物递送装置的方法
公开(公告)号：US09102105B2
公开(公告)日：2015-08-11
申请号：US13614883
申请日：2012-09-13
申请人： Edward J. Ellis , Jeanne Y. Ellis
发明人： Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： B29C70/70 , B29L31/00
CPC分类号： B29C70/70 , B29L2031/753
摘要： A method for forming an ocular drug delivery device includes the steps of: (1) forming a drug core containing an active agent, wherein the drug core has a barrier disposed all surfaces thereof except for a drug release surface which is left free of the barrier; (2) forming a drug release membrane over the drug release surface; and (3) forming the remaining portion of the device body by an overcast (overmold) process.
摘要翻译：用于形成眼药物递送装置的方法包括以下步骤：（1）形成含有活性剂的药物核心，其中所述药物核心具有除了不存在所述屏障的药物释放表面以外的所有表面的阻挡层 ; （2）在药物释放表面上形成药物释放膜; 和（3）通过阴影（包覆模制）工艺形成装置主体的剩余部分。

10. 发明授权

US4686267A Fluorine containing polymeric compositions useful in contact lenses 失效
标题翻译：含氟聚合物组合物可用于隐形眼镜
公开(公告)号：US4686267A
公开(公告)日：1987-08-11
申请号：US786846
申请日：1985-10-11
申请人： Edward J. Ellis , Jeanne Y. Ellis
发明人： Edward J. Ellis , Jeanne Y. Ellis
IPC分类号： G02C7/04 , C08F30/08 , C08F220/10 , C08F222/18 , C08F230/08 , C08F290/06 , G02B1/04
CPC分类号： G02B1/043 , C08F230/08 , C08F290/062 , C08F290/068
摘要： Improved contact lens compositions are achieved through incorporation of a fluorine containing mono or diester of itaconic acid in siloxane polymeric contact lens compositions. Copolymers include components which modify contact lens mechanical, optical and transport properties as well as surface characteristics to achieve at least some compositions having an oxygen permeability of at least DK35 with a refractive index of from 1.35 to 1.5 and a percent hydration below 2 percent of total weight. Contact lenses made of materials of this invention are highly permeable to oxygen and resistant to the deposition of tear components providing extended wear capability through improved biocompatibility.
摘要翻译：改进的隐形眼镜组合物通过在硅氧烷聚合物隐形眼镜组合物中掺入衣康酸的含氟单酯或二酯来实现。共聚物包括改变隐形眼镜机械，光学和输送性能以及表面特性的组分，以实现至少一些具有至少DK35的透氧度的组合物，折射率为1.35至1.5，水合百分数低于总量的2％重量。由本发明的材料制成的隐形眼镜对氧具有高度可渗透性，并且能够通过改进的生物相容性而提供延长的磨损能力来抵抗泪液组分的沉积。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式