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1. 发明授权

US5095960A Apparatus for filling bags with bulk material 失效
标题翻译：用于填充带有大量材料的袋子的装置
公开(公告)号：US5095960A
公开(公告)日：1992-03-17
申请号：US540558
申请日：1990-06-20
申请人： Bruno Grundler , Werner Muller
发明人： Bruno Grundler , Werner Muller
IPC分类号： B65B1/06 , B65B43/34
CPC分类号： B65B43/34
摘要： An apparatus for filling bags with bulk material includes a filling device for consecutively charging bags with the bulk material; a traction device leading into and out of a region of the filling device; and a plurality of spaced spreading devices, carried by the traction device, for expanding each bag to facilitate charging thereof by the filling device. Each spreading device has first and second mutually cooperating pivotal spreading fingers having a retracted state and an expanded state. The apparatus further has a first cam track extending generally along the traction device; a second cam track extending generally along the first cam track and being spaced therefrom; a device connected to the first cam track for lowering each spreading device relative to the traction device to introduce the spreading fingers into a bag located below the spreading device; and a device connected to the second cam track for placing the spreading fingers of each spreading device from the retracted state into the expanded state after introduction of the spreading fingers into the bag.
摘要翻译：一种用散装材料填充袋子的装置包括用于连续地对散装材料充电袋子的填充装置; 引导装置进入和离开填充装置的区域; 以及由牵引装置承载的多个间隔扩展装置，用于使每个袋膨胀以便于由填充装置对其充电。每个铺展装置具有第一和第二相互配合的枢转展开指，其具有缩回状态和展开状态。该装置还具有大致沿着牵引装置延伸的第一凸轮轨道; 大体上沿着第一凸轮轨道延伸并与其间隔开的第二凸轮轨道; 连接到所述第一凸轮轨道的装置，用于相对于所述牵引装置降低每个扩展装置，以将所述扩展指头引入位于所述扩展装置下方的袋中; 以及连接到第二凸轮轨道的装置，用于将扩展手指引入袋中之后，将每个扩展装置的扩展指针从缩回状态放置到展开状态。

2. 发明授权

US4129976A Apparatus for forming, filling and closing bags 失效
标题翻译：用于成型，填充和关闭袋子的装置
公开(公告)号：US4129976A
公开(公告)日：1978-12-19
申请号：US835426
申请日：1977-09-21
申请人： Bruno Grundler , Hans Heinzer , Werner Muller
发明人： Bruno Grundler , Hans Heinzer , Werner Muller
IPC分类号： B65B9/12
CPC分类号： B65B9/2042 , B29C65/18 , B29C65/7451 , B29C66/0342 , B29C66/1122 , B29C66/349 , B29C66/4312 , B29C66/81427 , B29C66/81431 , B29C66/81812 , B29C66/83543 , B29C66/8491 , B65B37/10 , B65B39/002 , B65B9/213 , B29C2035/1666 , B29C53/48 , B29C65/305 , B29C66/71 , B29C66/81415 , B29K2023/06 , B29K2101/12 , B29L2031/7128 , B29L2031/7166 , B65B9/2007 , Y10S493/936
摘要： An apparatus for forming, filling and closing bags has a hollow mandrel on which a hose is continuously formed from a sheet; two vertically reciprocating and horizontally oppositely movable shoes underneath the mandrel for cyclically pressing together a first hose portion and providing a transverse seam thereacross as the hose and the shoes move downwardly in unison; a folding device cyclically forming bottom flaps from a second hose portion at opposite sides of the hose at the lower end of the mandrel above the first hose portion; a clamping device for firmly grasping the hose at the second hose portion and backing the bottom flaps along the entire hose cross section as it pulls the hose downwardly from the mandrel while moving simultaneously downwardly with the shoes and while the hose part that terminates at the bottom flaps is being filled with goods by gravity; and a cutting device for cutting through the transverse seam when the shoes and the clamping device have pulled the hose to a predetermined low position for severing a previously filled hose portion as a separated, sealed bag from the upstream, still coherent hose.
摘要翻译：用于形成，填充和关闭袋的装置具有中空心轴，软管从其上连续形成; 在心轴下方的两个垂直往复和水平相对移动的鞋子，用于循环地将第一软管部分压合在一起，并且在软管和鞋子一致地向下移动时提供横向缝; 折叠装置，在第一软管部分上方的心轴的下端处，在软管的相对侧处的第二软管部分周期性地形成底部折翼; 夹紧装置，用于在第二软管部分处牢固地抓住软管并且沿着整个软管横截面沿着整个软管横截面背衬底板，当软管同时向下移动时从软管向下拉动软管，同时在底部终止的软管部分襟翼由于重力被充满货物; 以及切割装置，用于当鞋和夹紧装置将软管拉到预定的低位置时切割穿过横缝，用于将先前填充的软管部分作为分离的密封袋与上游的相干软管分开。

3. 发明授权

US09108618B2 Gearbox arrangement 有权
标题翻译：齿轮箱排列
公开(公告)号：US09108618B2
公开(公告)日：2015-08-18
申请号：US13805358
申请日：2011-06-27
申请人： Werner Muller
发明人： Werner Muller
IPC分类号： B60W10/02 , B60K23/04 , B60K17/16 , B60W10/115 , B60W30/18 , F16H48/10
CPC分类号： B60W10/023 , B60K17/165 , B60K23/04 , B60W10/115 , B60W30/18145 , B60W2540/18 , B60W2720/28 , B60W2720/406 , B60Y2200/22 , B60Y2200/41 , F16H48/10
摘要： A gearbox arrangement (1), which is arranged in a drive train of a multi-axle land vehicle (2), in particular a commercial vehicle, or a similar means of transportation, wherein at least one of said axles is driven, wherein at least one planetary drive (8) is associated with each of the axle halves (5) of a driven axle. The gearbox arrangement comprises at least one sensor device (7) for detecting a steering manipulation on the vehicle (2) and a control device (6). In order to have a gearbox arrangement (1) available that establishes a reliable, simply designed connection between the drive motor and driven wheels (4) with little effort and enables reliable control of the particular wheels (4) in regard to rotational speed and torque during drive and during deceleration, and thus realizes a controllable rotational speed compensation during cornering and significantly reduces the diameter and the constructed size of the power-split gearbox in particular for vehicles (2) having a high axle torque, the axle halves (5) are driven synchronously without differential and the control device (6) is provided with a hydrostatic device (11) that can be manipulated, by which hydrostatic device each of the wheels (4) rolling without slip maintains its torque.
摘要翻译：一种齿轮箱装置（1），其布置在多轴陆地车辆（2）的传动系中，特别是商用车辆或类似的运输工具，其中至少一个所述车轴被驱动，其中在至少一个行星驱动器（8）与从动轴的每个轴半部（5）相关联。齿轮箱装置包括用于检测车辆（2）上的转向操纵的至少一个传感器装置（7）和控制装置（6）。为了具有可用的齿轮箱装置（1），其能够以很小的努力在驱动马达和从动轮（4）之间建立可靠的，简单设计的连接，并且能够相对于转速和扭矩可靠地控制特定的车轮（4）在驱动期间和减速期间，因此在转弯期间实现可控的转速补偿，并且显着地减小动力分配齿轮箱的直径和结构尺寸，特别是具有高轴转矩的车辆（2），轴半部（5）在没有差速器的情况下同步地被驱动，并且控制装置（6）设置有可被操纵的静液压装置（11），通过该静液压装置，每个车轮（4）滚动而不滑动地保持其扭矩。

4. 发明申请

US20080120733A1 Rnai-Based Method for Selecting Transfected Eukaryotic Cells 审中-公开
标题翻译：基于Rnai的选择转染真核细胞的方法
公开(公告)号：US20080120733A1
公开(公告)日：2008-05-22
申请号：US11629709
申请日：2005-06-16
申请人： Martin Hafner , Karina Nawrath , Werner Muller
发明人： Martin Hafner , Karina Nawrath , Werner Muller
IPC分类号： A01K67/027 , C12N15/87 , C12N5/02 , C12N5/00 , C12N5/04 , A01H1/00 , C12N15/00
CPC分类号： C12N15/8218 , C12N15/63 , C12N15/8209 , C12N15/821
摘要： The invention relates to a method for the production of a eukaryotic cell selectable by inactivation or reduction of an endogenous gene function, comprising the steps of (a) introduction of one or more vectors into the cell and (b) expression of a siRNA and preferably shRNA coded by the one or more vectors, directed against an endogenous selectable gene and inactivating same, said siRNA or shRNA being the transcription product of an RNAi selection cassette, the selection cassette comprising a section of at least 19 nucleotides of the transcribed region of the gene, said selection being operatively linked to a promoter and a transcription termination signal. Furthermore, the invention relates to a eukaryotic cell comprising an RNAi selection cassette which is directed against an endogenous selectable gene and inactivates the function of said gene; wherein the RNAi selection cassette comprises a section of the gene with a length of at least 19 nucleotides which is operatively linked to a promoter and a transcription termination signal. Moreover, the invention relates to methods for the production of a transgenic mammal, comprising the steps: (a) injection of the embryonic stem cell according to the invention or of an embryonic stem cell selected according to the method of the invention in blastocysts of a mammal, (b) transfer of the blastocysts into the uterus of a mammal, and (c) carrying the transgenic mammal to full term. Finally, the invention relates to a method for the production of a transgenic plant.
摘要翻译：本发明涉及通过灭活或还原内源基因功能来选择性地生产真核细胞的方法，其包括以下步骤：（a）将一种或多种载体导入细胞，和（b）表达siRNA，优选由一个或多个载体编码的针对内源可选择基因并使其失活的shRNA，所述siRNA或shRNA是RNAi选择盒的转录产物，所述选择盒包含至少19个核苷酸的转录区的部分基因，所述选择可操作地连接到启动子和转录终止信号。此外，本发明涉及包含针对内源可选择基因并使所述基因的功能失活的RNAi选择盒的真核细胞; 其中所述RNAi选择盒包含长度为至少19个核苷酸的基因的一部分，其与启动子和转录终止信号有效连接。此外，本发明涉及生产转基因哺乳动物的方法，其包括以下步骤：（a）根据本发明的胚胎干细胞或根据本发明的方法选择的胚胎干细胞在囊胚中的注射哺乳动物，（b）将囊胚转移到哺乳动物的子宫中，和（c）将转基因哺乳动物全部携带。最后，本发明涉及生产转基因植物的方法。

5. 发明申请

US20070172421A1 Substituted pyrrolidine-2-ones 审中-公开
标题翻译：取代的吡咯烷-2-酮
公开(公告)号：US20070172421A1
公开(公告)日：2007-07-26
申请号：US11569164
申请日：2005-05-27
申请人： Werner Muller , Joachim Nozulak , Bernard Roy , Dominik Feuerbach
发明人： Werner Muller , Joachim Nozulak , Bernard Roy , Dominik Feuerbach
IPC分类号： A61K51/00 , A61K31/4709 , A61K31/454 , C07D417/14 , C07D403/14
CPC分类号： C07D207/26 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/06 , C07D405/06 , C07D405/10 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D417/04 , C07D417/06 , C07D417/14
摘要： The invention relates to compounds of formula (I) Wherein R1, R2, R3, R4 and n are as defined in the specification, to processes for their manufacture, to their use as pharmaceuticals, in diagnosis, as PET ligands and to pharmaceutical or diagnostic compositions comprising such compounds.
摘要翻译：本发明涉及式（I）的化合物，其中R 1，R 2，R 3，R 4，和n如说明书中所定义的，其制备方法，作为药物用作诊断用作PET配体，以及包含这些化合物的药物或诊断组合物。

6. 发明申请

US20060029939A1 Decomposition and modification of silicate and silicone by silase and use of the reversible enzyme 失效
标题翻译：通过硅藻分解和改性硅酸盐和硅氧烷并使用可逆酶
公开(公告)号：US20060029939A1
公开(公告)日：2006-02-09
申请号：US10530240
申请日：2003-10-02
申请人： Werner Muller , Heinz Schroder , Anatoli Krasko
发明人： Werner Muller , Heinz Schroder , Anatoli Krasko
IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C12N9/16 , C12N15/74
CPC分类号： C12N9/88 , C12P3/00
摘要： Silicatein is an enzyme of silicate-forming organisms used for the synthesis of their silicate scaffold. The present invention relates to the use of highly-expressed and highly active recombinant silicatein, silicatein isolated from natural sources after gene induction as well as silicatein-fusion proteins for the synthesis of amorphous silicon dioxide (silicic acids and silicates), siloxanes as well as modification of these compounds and their technical use.
摘要翻译：硅酸盐是一种用于合成硅酸盐支架的硅酸盐形成生物的酶。本发明涉及在基因诱导后从天然来源分离的高表达和高活性的重组硅酸蛋白，硅酸盐以及用于合成无定形二氧化硅（硅酸和硅酸盐），硅氧烷的硅酸盐融合蛋白以及硅氧烷 - 这些化合物的改性及其技术用途。

7. 发明授权

US5657128A Surgical microscope for conducting computer-supported stereotactic microsurgery and a method for operating the same 失效
标题翻译：用于进行计算机支持的立体定向显微外科手术的手术显微镜及其操作方法
公开(公告)号：US5657128A
公开(公告)日：1997-08-12
申请号：US670772
申请日：1996-06-24
申请人： Werner Muller , Joachim Luber
发明人： Werner Muller , Joachim Luber
IPC分类号： A61B90/20 , G01B9/04 , G02B21/00 , G02B21/22 , G02B21/36 , G01B11/14 , G01N21/00 , H04N7/18
CPC分类号： G01B9/04 , G02B21/0012 , G02B21/22 , G02B21/361 , A61B90/10 , A61B90/20
摘要： A defined determination of the field of view observed through a surgical microscope is made. To achieve this determination, the relative current position of the plane of the field of view to the position of an object detail of interest is detected in a sighting method with the aid of a position detection system operating according to the laser triangulation principle. As soon as the plane of the field of view and the object detail are coincident, then with the aid of detected optical system data, the position of the object detail with reference to the surgical microscope is determined and, with the detected coordinates of the surgical microscope, the position of the field of view is determined in space. The position detecting system required for this purpose operates on an optical basis and can be integrated into the optics of the surgical microscope.
摘要翻译：进行通过手术显微镜观察到的视野的确定的确定。为了实现该确定，借助于根据激光三角测量原理操作的位置检测系统，以瞄准方法来检测视场平面相对于感兴趣的物体细节的位置的相对当前位置。一旦观察平面和物体细节一致，则借助于检测到的光学系统数据，确定参考手术显微镜的物体细节的位置，并且利用检测到的外科手术坐标显微镜，视野的位置是在太空中确定的。为此目的所需的位置检测系统在光学基础上运行，并且可以集成到手术显微镜的光学元件中。

8. 发明授权

US5345087A Optical guide system for spatially positioning a surgical microscope 失效
标题翻译：用于空间定位手术显微镜的光导系统
公开(公告)号：US5345087A
公开(公告)日：1994-09-06
申请号：US11515
申请日：1993-02-01
申请人： Joachim Luber , Werner Muller , Martin Pelzer , Anette Reiss
发明人： Joachim Luber , Werner Muller , Martin Pelzer , Anette Reiss
IPC分类号： A61B17/00 , A61B34/00 , A61B34/20 , A61B90/50 , B25J13/00 , B25J19/02 , G02B21/24 , G01N21/86
CPC分类号： B25J13/00 , A61B34/74 , A61B90/50 , B25J19/021 , G02B21/24 , A61B2017/00694 , A61B2034/2055 , A61B2090/502 , A61B34/20 , A61B90/20
摘要： An instrument is mounted on a motorized positioning mechanism for providing a contactless guidance of the instrument. A transmitting unit and a receiving unit are arranged in a defined relative position to an operator and the instrument so that an evaluation unit positions the instrument via corresponding control signals with the aid of the registered signals of the receiving unit. A preferred application is the contactless guidance of a surgical microscope which tracks the head movements of the surgeon.
摘要翻译：仪器安装在电动定位机构上，用于提供仪器的非接触式引导。发送单元和接收单元被布置在与操作者和仪器的限定的相对位置中，使得评估单元借助于接收单元的登记信号经由相应的控制信号来定位乐器。优选的应用是跟踪外科医生的头部运动的手术显微镜的非接触式引导。

9. 发明授权

US5288987A Autofocusing arrangement for a stereomicroscope which permits automatic focusing on objects on which reflections occur 失效
标题翻译：用于立体显微镜的自动对焦装置，其允许自动聚焦反射发生的物体
公开(公告)号：US5288987A
公开(公告)日：1994-02-22
申请号：US950460
申请日：1992-09-24
申请人： Uwe Vry , Christian Lucke , Ulrich Sander , Werner Muller , Joachim Luber , Klaus Knupfer , Thomas Hellmuth , Rudiger Duchateau , Hartmut Wolf
发明人： Uwe Vry , Christian Lucke , Ulrich Sander , Werner Muller , Joachim Luber , Klaus Knupfer , Thomas Hellmuth , Rudiger Duchateau , Hartmut Wolf
IPC分类号： G02B21/22 , G02B21/24 , G01J1/20
CPC分类号： G02B21/241 , G02B21/22
摘要： The invention relates to a high-precision autofocusing arrangement for a stereomicroscope wherein a bar-shaped marking is projected via a cylinder optic on an object. The imaged bar-shaped marking is at least in one dimension less or equal to the resolution of the viewing beam path. A region of the objective not used optically is selected for projection as the pass-through pupil.
摘要翻译：本发明涉及一种用于立体显微镜的高精度自动聚焦装置，其中条形标记通过圆柱形光学镜件投射在物体上。成像的条形标记至少在与观察光束路径的分辨率小于或等于一个维度上。选择未被光学使用的物镜的区域作为直通光瞳投影。

10. 发明授权

US5284385A ABS control with rear pressure rate reduction when front pressure and time conditions are met 失效
标题翻译： ABS控制，当前压力和时间条件满足时，后压力降低
公开(公告)号：US5284385A
公开(公告)日：1994-02-08
申请号：US752555
申请日：1991-09-04
申请人： Elmar Muller , Werner Muller
发明人： Elmar Muller , Werner Muller
IPC分类号： B60T8/58 , B60T8/1761 , B60T8/1766 , B60T8/62 , B60T8/32
CPC分类号： B60T8/1766
摘要： Antilock control system wherein pressure at the front and rear axles is controlled in cycles which each include a pressure reduction followed by a build-up of the brake pressure in pulses having holding phases therebetween. When a build-up of brake pressure at the front axle exceeds a predetermined time, the rate of build-up at the rear axle is reduced. The system prevents too much pressure build-up at the rear axle during the dynamic load transfer which occurs when braking a vehicle having a high center of gravity relative to its wheel base.
摘要翻译： PCT No.PCT / EP90 / 00204 Sec。 371日期1991年9月4日 102（e）1991年9月4日PCT PCT 1990年2月9日PCT公布。出版物WO90 / 11916 日期为1990年10月18日。其中，前后轴的压力以周期为单位进行控制的非锁定控制系统，每个循环包括压力降低，随后在其间保持相位的脉冲中累积制动压力。当前轴处的制动压力的累积超过预定时间时，后轴处的积聚速率降低。在制动具有相对于其车轮底座的高重心的车辆时的动态载荷传递期间，该系统防止在后桥处产生过大的压力。

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