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1. 发明申请

US20080045937A1 PATENT FORAMEN OVALE CLOSURE DEVICE AND METHODS FOR DETERMINING RF DOSE FOR PATENT FORAMEN OVALE CLOSURE 有权
标题翻译：专利文献OVALE封闭装置及其用于确定OVO封闭专利的RF剂量的方法
公开(公告)号：US20080045937A1
公开(公告)日：2008-02-21
申请号：US11671428
申请日：2007-02-05
申请人： Brian Whisenant , Clark Davis , Scott Miles , Richard Linder , Daryl Edmiston
发明人： Brian Whisenant , Clark Davis , Scott Miles , Richard Linder , Daryl Edmiston
IPC分类号： A61B18/18 , A61B17/04
CPC分类号： A61B5/053
摘要： A medical system and device for use in delivering RF energy to a tissue opening and a method for determining an RF dose is disclosed. In one embodiment, the medical device includes an electrode or anchor and one or more devices, such as an impedance electrode, RF electrode and/or thermocouple. The electrode or anchor can be deployed from a delivery shaft inside the left atrium, for example, of a heart and substantially conform to the tissue proximate the tissue opening. Tissue characteristics, such as temperature and/or impedance, can be measured, before, during and after application of RF energy to the tissue, by one or more devices to determine an RF dose. After energy is applied to the tissue between the left and right electrodes, the left electrode can be removed from the left atrium by being received back into the delivery shaft and the delivery shaft thereafter removed from the opening.
摘要翻译：公开了一种用于将RF能量递送到组织开口的医疗系统和装置以及用于确定RF剂量的方法。在一个实施例中，医疗装置包括电极或锚定器以及一个或多个装置，例如阻抗电极，RF电极和/或热电偶。电极或锚固件可以从左心房内的输送轴例如心脏展开，并且基本上符合组织开口附近的组织。组织特征如温度和/或阻抗可以在RF能量施加到组织之前，期间和之后由一个或多个装置测量以确定RF剂量。在将能量施加到左右电极之间的组织之后，左电极可以通过被收回到输送轴中而从左心房移除，此后从开口移除输送轴。

2. 发明申请

US20080033421A1 METHODS, SYSTEMS, AND DEVICES FOR CLOSING A PATENT FORAMEN OVALE USING MECHANICAL STRUCTURES 失效
标题翻译：使用机械结构封闭专利的瓦楞纸的方法，系统和装置
公开(公告)号：US20080033421A1
公开(公告)日：2008-02-07
申请号：US11754936
申请日：2007-05-29
申请人： Clark Davis , Scott Miles , Daryl Edmiston , Brian Whisenant , Richard Linder , Dewayne Fox
发明人： Clark Davis , Scott Miles , Daryl Edmiston , Brian Whisenant , Richard Linder , Dewayne Fox
IPC分类号： A61B18/12 , A61B17/08
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00557 , A61B2017/00575 , A61B2017/00623 , A61B2018/1435
摘要： A medical device is disclosed that can include a first atrial anchor, a first delivery shaft linked to the first atrial anchor, wherein the first delivery shaft is adapted to move the first atrial anchor, a second atrial anchor, a second delivery shaft linked to the second atrial anchor, wherein the second delivery shaft is adapted to move the second atrial anchor, and a biasing member linking either (i) the first atrial anchor to the first delivery shaft or (ii) the second atrial anchor to the second delivery shaft. The medical device can include an insulation material coupled to one or more of the first or second atrial anchors, or the first or second delivery shaft. A method for treating an internal tissue opening is also disclosed wherein a first and second electrode can be operated between unipolar and bipolar modes to initiate tissue damage, thereby inducing tissue regrowth.
摘要翻译：公开了一种医疗装置，其可以包括第一心房锚，连接到第一心房锚的第一输送轴，其中第一输送轴适于移动第一心房锚，第二心房锚，第二输送轴第二心房锚，其中第二输送轴适于移动第二心房锚，以及将（i）第一心房锚与第一输送轴连接的偏压构件，或（ii）第二心房锚固件连接到第二输送轴。医疗装置可以包括耦合到第一或第二心房锚或第一或第二输送轴中的一个或多个的绝缘材料。还公开了一种用于治疗内部组织开口的方法，其中第一和第二电极可以在单极和双极模式之间操作以引发组织损伤，从而诱导组织再生长。

3. 发明申请

US20080033425A1 METHODS, SYSTEMS, AND DEVICES FOR SENSING, MEASURING, AND CONTROLLING CLOSURE OF A PATENT FORAMEN OVALE 有权
标题翻译：用于传感，测量和控制专利的封闭的方法，系统和装置
公开(公告)号：US20080033425A1
公开(公告)日：2008-02-07
申请号：US11754978
申请日：2007-05-29
申请人： Clark Davis , Scott Miles , Daryl Edmiston , Brian Whisenant , Dewayne Fox
发明人： Clark Davis , Scott Miles , Daryl Edmiston , Brian Whisenant , Dewayne Fox
IPC分类号： A61B18/14 , A61N1/18
CPC分类号： A61B17/0057 , A61B18/1492 , A61B2017/00026 , A61B2017/00084 , A61B2017/00575 , A61B2017/00623 , A61B2017/00867 , A61B2018/00791 , A61B2018/00875 , A61B2090/378
摘要： A medical device for reducing the size of a Patent Foramen Ovale is disclosed. The medical device can include a first electrode, a second electrode, and at least one sensor mounted to at least one of the first electrode or the second electrode, the at least one sensor adapted to sense at least one operating parameter of the medical device or the patient to facilitate closure of the Patent Foramen Ovale. The medical device can also include a delivery shaft coupled to the first electrode, wherein the delivery shaft includes an indicia for determining the position of the first electrode relative to the second electrode. A method for determining a characteristic of an internal tissue opening is also disclosed. The method can include the steps of introducing a detectable fluid in the right atrium of a heart and then detecting the location of the detectable fluid in the heart.
摘要翻译：公开了一种用于减小专利孔径的医疗装置。医疗装置可以包括第一电极，第二电极和安装到第一电极或第二电极中的至少一个的至少一个传感器，所述至少一个传感器适于感测医疗装置的至少一个操作参数或患者便利关闭专利孔卵巢。医疗装置还可以包括联接到第一电极的输送轴，其中输送轴包括用于确定第一电极相对于第二电极的位置的标记。还公开了一种用于确定内部组织开口的特性的方法。该方法可以包括在心脏的右心房中引入可检测流体，然后检测心脏中可检测流体的位置的步骤。

4. 发明申请

US20050192627A1 Patent foramen ovale closure devices, delivery apparatus and related methods and systems 审中-公开
标题翻译：卵圆孔闭合装置，输送装置及相关方法和系统
公开(公告)号：US20050192627A1
公开(公告)日：2005-09-01
申请号：US11102095
申请日：2005-04-08
申请人： Brian Whisenant , Clark Davis , Daryl Edmiston
发明人： Brian Whisenant , Clark Davis , Daryl Edmiston
IPC分类号： A61B20060101 , A61B17/00 , A61B17/08 , A61D1/00
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/00867 , A61B2017/00893
摘要： The present invention includes systems, methods, and apparatus configured to close an internal tissue opening, such as an internal tissue opening cased by an atrial septal defect including a patent foramen ovale defect, ventricular septal defect, patent ductus arterosus defect, or the like. For example, a closure device includes a right anchor cooperatively coupled with a left anchor, where the right anchor and left anchor are configured to be positioned about the internal tissue opening. The left and/or right anchor are configured to close the internal tissue opening in one instance, and to provide tissue stimulating or growth-encouraging substances at the tissue opening. Additional aspects of the invention relate to shape, formation, positioning, and detachment of the closure device about the internal tissue opening.
摘要翻译：本发明包括用于封闭内部组织开口的系统，方法和装置，所述内部组织开口例如由包括卵孔缺失专利，室间隔缺损，导管未闭导管缺损等的房间隔缺损引起的内部组织开口。例如，闭合装置包括与左锚配合地联接的右锚，其中右锚和左锚配置成围绕内组织开口定位。左和/或右锚固件被构造成在一个实例中关闭内部组织开口，并且在组织开口处提供组织刺激或促进生长的物质。本发明的另外的方面涉及封闭装置围绕内部组织开口的形状，形成，定位和分离。

5. 发明申请

US20070123934A1 Delivery system for patent foramen ovale closure device 审中-公开
标题翻译：卵圆孔闭合装置专用输卵管系统
公开(公告)号：US20070123934A1
公开(公告)日：2007-05-31
申请号：US11534996
申请日：2006-09-25
申请人： Brian Whisenant , Clark Davis , Daryl Edmiston
发明人： Brian Whisenant , Clark Davis , Daryl Edmiston
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623
摘要： A medical system for use in reducing the size of an internal tissue opening is disclosed. The medical system can include a patent foramen ovale or PFO closure device and a delivery device therefore. The PFO closure device can include left and right anchors connected by a stem. The delivery device is configured to selectively deploy at least one of the right or left anchors of PFO closure device so as to enable a practitioner to adjust PFO closure device during the positioning procedure. In one embodiment, the delivery device includes a filament operating shaft linked to the right anchor by one or more filaments. A practitioner can move the filament operating shaft to selectively deploy and retract the right anchor during positioning of the PFO closure device. Furthermore, the delivery device comprises a tether shaft for coupling delivery device to PFO closure device. In one embodiment, the tether shaft comprises a first portion and a flexible second portion, wherein the flexible second portion is at a distal end of the tether shaft.
摘要翻译：公开了一种用于减小内部组织开口尺寸的医疗系统。因此，医疗系统可以包括卵孔或PFO封闭装置和输送装置。 PFO闭合装置可以包括由杆连接的左和右锚定件。输送装置构造成选择性地展开PFO闭合装置的右或左锚固件中的至少一个，以使得从业者能够在定位过程期间调节PFO闭合装置。在一个实施例中，输送装置包括通过一个或多个细丝连接到右锚的细丝操作轴。在定位PFO闭合装置期间，从业者可以移动细丝操作轴以选择性地展开和缩回右锚。此外，输送装置包括用于将输送装置耦合到PFO闭合装置的系绳轴。在一个实施例中，系绳轴包括第一部分和柔性第二部分，其中柔性第二部分位于系绳轴的远端。

6. 发明申请

US20050125032A1 Patent foramen ovale (PFO) closure devices, delivery apparatus and related methods and systems 审中-公开
标题翻译：专利孔卵孔（PFO）闭合装置，输送装置及相关方法和系统
公开(公告)号：US20050125032A1
公开(公告)日：2005-06-09
申请号：US10964311
申请日：2004-10-12
申请人： Brian Whisenant , Clark Davis , Daryl Edmiston
发明人： Brian Whisenant , Clark Davis , Daryl Edmiston
IPC分类号： A61B20060101 , A61B17/00 , A61B17/08 , A61D1/00
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/00893
摘要： Devices for closure of a patent foramen ovale, apparatus for delivery of the closure device and methods and systems for closing a patent foramen ovale are disclosed.
摘要翻译：公开了用于封闭卵孔卵孔的装置，用于输送闭合装置的装置以及用于闭合卵孔卵泡的方法和系统。

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