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    • 2. 发明授权
    • Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments
    • 用于在不均匀环境中获取高分辨率光谱数据或高清晰度图像的方法和装置
    • US07944206B2
    • 2011-05-17
    • US12158364
    • 2006-12-14
    • Lucio FrydmanBoaz ShapiraAssaf Tal
    • Lucio FrydmanBoaz ShapiraAssaf Tal
    • G01V3/00
    • G01R33/56563G01R33/4822G01R33/485G01R33/5615G01R33/5616G01R33/5617
    • A method and apparatus for treating a sample for acquiring high-definition magnetic resonance images (MRI images) or high resolution nuclear magnetic resonance (NMR) spectra even in the presence of magnetic field distortions within one or multiple scans. The spatial nature and temporal dependence of the field inhomogeneities are determined a priori using any of several literature procedures. A static or oscillating magnetic field gradient is applied on the sample so as to endow spins at different positions within the sample with different resonance frequencies. A phase- and amplitude-modulated radiofrequency (RF) pulse is applied in unison with the magnetic field gradient so as to endow spins at different positions within the sample with a homogeneous excitation/inversion profile. The nature of the spatially-selective RF irradiation is tailored in such a way that, when added on top of the effects of the inhomogeneities, the spins' evolution phases and their signal amplitudes at the time of the acquisition become independent of the inhomogeneities. The spin signals thus created are captured and decoded, so as to obtain the spins' response as if the inhomogeneity was not present. The collected data is processed to a suitable rearrangement and Fourier analysis procedure to retrieve a final undistorted image or spectrum. The magnetic field gradient can be oscillated to impose this kind of inhomogeneity corrections on multiple spatial dimensions sequentially, or simultaneously.
    • 即使在一次或多次扫描期间存在磁场失真的情况下,也可以用于处理样品以获取高分辨率磁共振图像(MRI图像)或高分辨率核磁共振(NMR)光谱的方法和装置。 使用几种文献程序中的任何一种先验地确定场不均匀性的空间性质和时间依赖性。 对样品施加静态或振荡磁场梯度,以使样品中具有不同共振频率的不同位置旋转。 将相位和幅度调制的射频(RF)脉冲与磁场梯度一致地施加,以便以均匀的激发/反演曲线赋予样品内不同位置的旋转。 空间选择性射频辐射的性质是这样定义的:当在不均匀性的影响之上加入时,获取时的自旋演化阶段和它们的信号幅度变得与不均匀性无关。 如此创建的自旋信号被捕捉和解码,以便获得自旋的响应,就好像不存在不均匀性一样。 将收集的数据处理成合适的重排和傅立叶分析程序以检索最终的未失真图像或光谱。 可以振荡磁场梯度以依次或同时地对多个空间维度施加这种不均匀性校正。
    • 3. 发明申请
    • METHOD AND APPARATUS FOR ACQUIRING HIGH RESOLUTION SPECTRAL DATA OR HIGH DEFINITION IMAGES IN INHOMOGENEOUS ENVIRONMENTS
    • 在非均质环境中获取高分辨率光谱数据或高定义图像的方法和装置
    • US20100001727A1
    • 2010-01-07
    • US12158364
    • 2006-12-14
    • Lucio FrydmanBoaz ShapiraAssaf Tal
    • Lucio FrydmanBoaz ShapiraAssaf Tal
    • G01R33/48G01R33/44
    • G01R33/56563G01R33/4822G01R33/485G01R33/5615G01R33/5616G01R33/5617
    • A method and apparatus for treating a sample for acquiring high-definition magnetic resonance images (MRI images) or high resolution nuclear magnetic resonance (NMR) spectra even in the presence of magnetic field distortions within one or multiple scans. The spatial nature and temporal dependence of the field inhomogeneities are determined a priori using any of several literature procedures. A static or oscillating magnetic field gradient is applied on the sample so as to endow spins at different positions within the sample with different resonance frequencies. A phase- and amplitude-modulated radiofrequency (RF) pulse is applied in unison with the magnetic field gradient so as to endow spins at different positions within the sample with a homogeneous excitation/inversion profile. The nature of the spatially-selective RF irradiation is tailored in such a way that, when added on top of the effects of the inhomogeneities, the spins' evolution phases and their signal amplitudes at the time of the acquisition become independent of the inhomogeneities. The spin signals thus created are captured and decoded, so as to obtain the spins' response as if the inhomogeneity was not present. The collected data is processed to a suitable rearrangement and Fourier analysis procedure to retrieve a final undistorted image or spectrum. The magnetic field gradient can be oscillated to impose this kind of inhomogeneity corrections on multiple spatial dimensions sequentially, or simultaneously.
    • 即使在一次或多次扫描期间存在磁场失真的情况下,也可以用于处理样品以获取高清晰度磁共振图像(MRI图像)或高分辨率核磁共振(NMR)光谱的方法和装置。 使用几种文献程序中的任何一种先验地确定场不均匀性的空间性质和时间依赖性。 对样品施加静态或振荡磁场梯度,以使样品中具有不同共振频率的不同位置旋转。 将相位和幅度调制的射频(RF)脉冲与磁场梯度一致地施加,以便以均匀的激发/反演曲线赋予样品内不同位置的旋转。 空间选择性射频辐射的性质是这样定义的:当在不均匀性的影响之上加入时,获取时的自旋演化阶段和它们的信号幅度变得与不均匀性无关。 如此创建的自旋信号被捕捉和解码,以便获得自旋的响应,就好像不存在不均匀性一样。 将收集的数据处理成合适的重排和傅立叶分析程序以检索最终的未失真图像或光谱。 可以振荡磁场梯度以依次或同时地对多个空间维度施加这种不均匀性校正。