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1. 发明授权

US06638498B2 Molecularly imprinted polymers for the treatment and diagnosis of medical conditions 失效
公开(公告)号：US06638498B2
公开(公告)日：2003-10-28
申请号：US09893643
申请日：2001-06-29
申请人： Bernard S. Green , Morris Priwler
发明人： Bernard S. Green , Morris Priwler
IPC分类号： A61K3174
CPC分类号： B01J20/268 , A61K31/785 , A61K31/787 , C08F226/06 , C08F246/00
摘要： Improved molecularly imprinted polymers (MIPs) with both higher and more specific binding capacity for particular bile acids and/or salts, including the synthesis of such MIPs, the compounds themselves, and specific applications thereof. As an example of a particularly preferred specific application of these compounds, the present invention encompasses the use of the MIPs as sequestrants in the gastrointestinal tract, particularly in order to bind and therefore remove toxins from the gastrointestinal tract. In addition, the present invention is also useful for treatment of various diseases which are related to, and/or characterized by, an effect of bile acids and salts, such as atherosclerosis, liver disease and various diseases of the gastrointestinal tract. The MIP compounds of the present invention are also useful for combination therapy with other medications and for diagnosis and monitoring of diseases.

2. 发明授权

US06336738B1 System and method for high intensity irradiation 失效
标题翻译：高强度照射系统和方法
公开(公告)号：US06336738B1
公开(公告)日：2002-01-08
申请号：US08901663
申请日：1997-07-28
申请人： Daniel Feuermann , Jeffrey M. Gordon , Morris Priwler , Harald Ries
发明人： Daniel Feuermann , Jeffrey M. Gordon , Morris Priwler , Harald Ries
IPC分类号： F21V800
CPC分类号： G02B6/0006
摘要： A system and method for concentrating the intensity of light emitted by a high-intensity source for delivery to a remote target, so that the power density of the active radiating region of the source is nearly restored at the target. The source is surrounded by a plurality of nonimaging concentrators. If the source is elongated, the concentrators are similarly elongated and parallel to the source. If the source is compact, the preferred geometric pattern of the concentrators is dodecahedral. The geometry of the concentrators is designed in accordance with the edge-ray principle of nonimaging optics. Channels such as optical fibers or light pipes are coupled optically to the absorbers of the concentrators, to conduct the concentrated light to the remote target.
摘要翻译：一种用于将由高强度源发射的光的强度集中用于传送到远程目标的系统和方法，使得源的有源辐射区域的功率密度在目标处几乎恢复。源被多个非成像集中器包围。如果源是细长的，则集中器类似地伸长并平行于源。如果源是紧凑的，集中器的优选几何图案是十二面体。集中器的几何形状是根据非成像光学元件的边缘射线原理设计的。诸如光纤或光管的通道光学耦合到集中器的吸收体，以将集中的光导向远程目标。

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