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1. 发明申请

US20100189334A1 FUNDUS OCULI OBSERVATION DEVICE, FUNDUS OCULI IMAGE PROCESSING DEVICE, AND FUNDUS OCULI OBSERVATION METHOD 审中-公开
标题翻译：基金OCULI观察设备，FUNDUS OCULI图像处理设备和基金OCULI观察方法
公开(公告)号：US20100189334A1
公开(公告)日：2010-07-29
申请号：US12733559
申请日：2008-09-09
申请人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
发明人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
IPC分类号： G06K9/00
CPC分类号： A61B3/102 , A61B3/0058 , A61B3/1225 , A61B3/14
摘要： A fundus oculi observation device 1 has a function of forming a tomographic image of a fundus oculi Ef and a function of capturing a two-dimensional image of the surface of the fundus oculi Ef (a fundus oculi image Ef′). An arithmetic and control unit 200: specifies a vascular region in the tomographic image and a vascular region in the fundus oculi image Ef′; obtains a common region of the vascular region in the tomographic image and the vascular region in the fundus oculi image Ef′ and specifies the common region in the tomographic image; erases an image of the common region from the tomographic image and estimates a layer position within the common region to add an image representing this layer position to the common region; and obtains the layer thickness of the fundus oculi Ef in the common region based on the image representing this layer position.
摘要翻译：眼底观察装置1具有形成眼底Ef的断层图像和捕获眼底Ef（眼底图像Ef'）的表面的二维图像的功能的功能。算术和控制单元200：指定断层图像中的血管区域和眼底图像Ef'中的血管区域; 获取眼底图像中的血管区域的共同区域和眼底图像Ef'中的血管区域，并指定断层图像中的共同区域; 从断层图像中擦除公共区域的图像，并估计公共区域内的层位置，以将表示该层位置的图像添加到公共区域; 并且基于表示该层位置的图像，获得公共区域中眼底Ef的层厚度。

2. 发明授权

US08408704B2 Fundus oculi observation device, ophthalmologic image processing device, and program 有权
标题翻译：眼底观察装置，眼科图像处理装置和程序
公开(公告)号：US08408704B2
公开(公告)日：2013-04-02
申请号：US12733485
申请日：2008-09-09
申请人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
发明人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
IPC分类号： A61B3/14
CPC分类号： A61B3/102
摘要： A fundus oculi observation device capable of defining which part in the result of analysis of the layer thickness of a fundus oculi is a part obtained by analyzing a vascular region is provided. A fundus oculi observation device 1 forms a plurality of tomographic images G1-Gm of a fundus oculi Ef. A layer thickness distribution calculator 231 calculates layer thickness distribution of the fundus oculi Ef in a cross section of a tomographic image G based on the tomographic images G1-Gm. A vascular region specifying part 234 specifies a vascular region in the tomographic image G. A controller 210 controls a display 240A to display layer thickness distribution information representing the layer thickness distribution and to also display vascular position information representing the position of the vascular region on the layer thickness distribution information.
摘要翻译：本发明提供一种眼底观察装置，其能够确定眼底层厚度的分析结果中的哪一部分是通过分析血管区域获得的部分。眼底观察装置1形成眼底Ef的多个断层图像G1-Gm。层厚度分布计算器231基于断层图像G1-Gm计算断层图像G的横截面中眼底Ef的层厚度分布。血管区域指定部234指定断层图像G中的血管区域。控制器210控制显示器240A以显示表示层厚度分布的层厚度分布信息，并且还显示表示血管区域的位置的血管位置信息层厚度分布信息。

3. 发明申请

US20100194757A1 FUNDUS OCULI OBSERVATION DEVICE, OPHTHALMOLOGIC IMAGE PROCESSING DEVICE, AND PROGRAM 有权
标题翻译： FUNDUS OCULI观察设备，眼科图像处理设备和程序
公开(公告)号：US20100194757A1
公开(公告)日：2010-08-05
申请号：US12733485
申请日：2008-09-09
申请人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
发明人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
IPC分类号： G06T7/00 , G06T11/20
CPC分类号： A61B3/102
摘要： A fundus oculi observation device capable of defining which part in the result of analysis of the layer thickness of a fundus oculi is a part obtained by analyzing a vascular region is provided. A fundus oculi observation device 1 forms a plurality of tomographic images G1-Gm of a fundus oculi Ef. A layer thickness distribution calculator 231 calculates layer thickness distribution of the fundus oculi Ef in a cross section of a tomographic image G based on the tomographic images G1-Gm. A vascular region specifying part 234 specifies a vascular region in the tomographic image G. A controller 210 controls a display 240A to display layer thickness distribution information representing the layer thickness distribution and to also display vascular position information representing the position of the vascular region on the layer thickness distribution information.
摘要翻译：本发明提供一种眼底观察装置，其能够确定眼底层厚度的分析结果中的哪一部分是通过分析血管区域获得的部分。眼底观察装置1形成眼底Ef的多个断层图像G1-Gm。层厚度分布计算器231基于断层图像G1-Gm计算断层图像G的横截面中眼底Ef的层厚度分布。血管区域指定部234指定断层图像G中的血管区域。控制器210控制显示器240A以显示表示层厚度分布的层厚度分布信息，并且还显示表示血管区域的位置的血管位置信息层厚度分布信息。

4. 发明授权

US07828437B2 Fundus oculi observation device and fundus oculi image processing device 有权
标题翻译：眼底观察装置和眼底图像处理装置
公开(公告)号：US07828437B2
公开(公告)日：2010-11-09
申请号：US12035879
申请日：2008-02-22
申请人： Tsutomu Kikawa , Takashi Fujimura , Hiroyuki Aoki , Jun Suehiro , Yasufumi Fukuma
发明人： Tsutomu Kikawa , Takashi Fujimura , Hiroyuki Aoki , Jun Suehiro , Yasufumi Fukuma
IPC分类号： A61B3/14
CPC分类号： G01B9/02044 , A61B3/102 , G01B9/0203 , G01B9/02083 , G01B9/02089 , G01B9/02091 , G01B2290/65
摘要： A fundus oculi observation device comprises: an image forming part configured to optically acquire data and form a tomographic image of a fundus oculi of an eye; a storage configured to store optical information representing a state of an ocular optical system of the eye; a calculator configured to calculate a magnification of the ocular optical system, based on the optical information; and an analyzer configured to analyze the tomographic image, based on the magnification.
摘要翻译：眼底观察装置包括：图像形成部，被配置为光学地获取数据并形成眼睛的眼底的断层图像; 存储器，被配置为存储表示眼睛的眼睛光学系统的状态的光学信息; 计算器，被配置为基于所述光学信息计算所述眼睛光学系统的倍率; 以及分析器，其被配置为基于所述放大率来分析所述断层图像。

5. 发明授权

US07905596B2 Fundus observation device, an ophthalmologic image processing unit, an ophthalmologic image processing program, and an ophthalmologic image processing method 有权
标题翻译：眼底观察装置，眼科图像处理单元，眼科图像处理程序和眼科图像处理方法
公开(公告)号：US07905596B2
公开(公告)日：2011-03-15
申请号：US11760314
申请日：2007-06-08
申请人： Hiroyuki Aoki , Takashi Fujimura , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
发明人： Hiroyuki Aoki , Takashi Fujimura , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
IPC分类号： A61B3/14 , A61B3/10 , A61B3/00
CPC分类号： A61B3/102 , G06T7/12 , G06T7/174 , G06T7/181 , G06T2207/10101 , G06T2207/30041
摘要： First image forming part forms a two-dimensional surface image of a fundus oculi of an eye based on optically obtained data. Second image forming part forms tomographic images of fundus oculi based on data obtained by optically scanning a region of the surface of fundus oculi corresponding to at least part of two-dimensional image. Accumulated image generating part generates an accumulated image by accumulating the formed tomographic images in a depth-wise direction. Extracting part extracts first vascular territory corresponding to a fundus oculi vessel from two-dimensional image formed by first image forming part, and also extracts second vascular territory corresponding to a fundus oculi vessel from accumulated image generated by accumulated image generating part. Specification part specifies a position of a vascular cross sectional region corresponding to a cross section of a fundus oculi vessel in the tomographic image based on extracted first vascular territory and extracted second vascular territory.
摘要翻译：第一图像形成部件基于光学获得的数据形成眼睛的眼底的二维表面图像。第二图像形成部分基于通过光学扫描与至少部分二维图像相对应的眼底表面的区域获得的数据来形成眼底的断层图像。累积图像生成部通过在深度方向累积形成的断层图像来生成累积图像。提取部分从由第一图像形成部分形成的二维图像中提取与眼底容器相对应的第一血管区域，并且从由累积图像生成部分生成的累积图像中提取与眼底容器对应的第二血管区域。规格部分基于提取的第一血管区域和提取的第二血管区域来指定与断层图像中的眼底血管的横截面对应的血管横截面区域的位置。

6. 发明授权

US07756311B2 Optical image measuring device, optical image measuring program, fundus observation device, and fundus observation program 有权
标题翻译：光学图像测量装置，光学图像测量程序，眼底观察装置和眼底观察程序
公开(公告)号：US07756311B2
公开(公告)日：2010-07-13
申请号：US11545270
申请日：2006-10-10
申请人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
发明人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
IPC分类号： G06K9/00 , G01B9/02
CPC分类号： G01N21/4795 , A61B3/102 , A61B3/145 , G01N2021/1787
摘要： An optical image measuring device which can form a highly reliable image even if an object moves during scanning of a signal light is provided. An optical image forming device 1 comprises: an interferometer that splits a low coherence light L0 into a signal light LS and a reference light LR and generates an interference light LC by overlaying the signal light LS reflected by a fundus oculi with the reference light LR reflected by a reference mirror 14; a CCD 34 which receives the interference light LC and outputs a detection signal; Galvanometer mirrors 22 and 23 to scan the signal light LS in a main scanning direction and a sub-scanning direction; and a computer 40 forming tomographic images G1 to Gm along the main scanning direction at different positions of the sub-scanning direction. The Galvanometer mirrors 22 and 23 scan the signal light LS in a given direction crossing the main scanning direction, and the computer 40 forms a tomographic image for correction GR along the given direction to correct displacement of each topographic image Gi based on the tomographic image for correction GR.
摘要翻译：提供了即使在信号光的扫描期间物体移动时也可以形成高可靠性图像的光学图像测量装置。光学图像形成装置1包括：干涉仪，其将低相干光L0分解成信号光LS和参考光LR，并通过将由眼底反射的信号光LS与反射的参考光LR重叠而产生干涉光LC 通过参考反射镜14; CCD34，其接收干涉光LC并输出检测信号; 电流计镜22和23在主扫描方向和副扫描方向扫描信号光LS; 以及在副扫描方向的不同位置沿着主扫描方向形成断层图像G1〜Gm的计算机40。电流计反射镜22和23沿与主扫描方向相交的给定方向扫描信号光LS，并且计算机40沿着给定方向形成用于校正GR的断层图像，以校正基于断层图像的每个地形图像Gi的位移校正GR。

7. 发明申请

US20080204655A1 FUNDUS OCULI OBSERVATION DEVICE AND FUNDUS OCULI IMAGE PROCESSING DEVICE 有权
标题翻译：基金OCULI观察设备和基金OCULI图像处理设备
公开(公告)号：US20080204655A1
公开(公告)日：2008-08-28
申请号：US12035879
申请日：2008-02-22
申请人： Tsutomu KIKAWA , Takashi Fujimura , Hiroyuki Aoki , Jun Suehiro , Yasufumi Fukuma
发明人： Tsutomu KIKAWA , Takashi Fujimura , Hiroyuki Aoki , Jun Suehiro , Yasufumi Fukuma
IPC分类号： A61B3/14
CPC分类号： G01B9/02044 , A61B3/102 , G01B9/0203 , G01B9/02083 , G01B9/02089 , G01B9/02091 , G01B2290/65
摘要： A fundus oculi observation device comprises: an image forming part configured to optically acquire data and form a tomographic image of a fundus oculi of an eye; a storage configured to store optical information representing a state of an ocular optical system of the eye; a calculator configured to calculate a magnification of the ocular optical system, based on the optical information; and an analyzer configured to analyze the tomographic image, based on the magnification.
摘要翻译：眼底观察装置包括：图像形成部，被配置为光学地获取数据并形成眼睛的眼底的断层图像; 存储器，被配置为存储表示眼睛的眼睛光学系统的状态的光学信息; 计算器，被配置为基于所述光学信息计算所述眼睛光学系统的倍率; 以及分析器，其被配置为基于所述放大率来分析所述断层图像。

8. 发明授权

US07789511B2 Eye movement measuring apparatus, eye movement measuring method and recording medium 有权
标题翻译：眼动测量仪，眼动测量方法和记录介质
公开(公告)号：US07789511B2
公开(公告)日：2010-09-07
申请号：US11845358
申请日：2007-08-27
申请人： Hiroyuki Aoki , Takashi Fujimura , Hisashi Tsukada , Tsutomu Kikawa , Yasufumi Fukuma
发明人： Hiroyuki Aoki , Takashi Fujimura , Hisashi Tsukada , Tsutomu Kikawa , Yasufumi Fukuma
IPC分类号： A61B3/113
CPC分类号： A61B5/0066 , A61B3/102 , A61B3/113 , G06T7/246 , G06T2207/10101 , G06T2207/30041
摘要： An eye movement measuring apparatus comprises: an image forming part configured to obtain data optically to form a fundus oculi image of an eye based on the obtained data; and an image analysis part configured to analyze the formed fundus oculi image to determine eye movement of the eye.
摘要翻译：眼动测量装置包括：图像形成部，被配置为基于获得的数据光学地获得眼睛的眼底图像; 以及图像分析部，被配置为分析形成的眼底图像以确定眼睛的眼睛运动。

9. 发明申请

US20100142780A1 OPTICAL IMAGE MEASURING DEVICE, OPTICAL IMAGE MEASURING PROGRAM, FUNDUS OBSERVATION DEVICE, AND FUNDUS OBSERVATION PROGRAM 有权
标题翻译：光学图像测量设备，光学图像测量程序，基金观察设备和基金观察程序
公开(公告)号：US20100142780A1
公开(公告)日：2010-06-10
申请号：US11545270
申请日：2006-10-10
申请人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
发明人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
IPC分类号： G06K9/00
CPC分类号： G01N21/4795 , A61B3/102 , A61B3/145 , G01N2021/1787
摘要： An optical image measuring device which can form a highly reliable image even if an object moves during scanning of a signal light is provided. An optical image forming device 1 comprises: an interferometer that splits a low coherence light L0 into a signal light LS and a reference light LR and generates an interference light LC by overlaying the signal light LS reflected by a fundus oculi with the reference light LR reflected by a reference mirror 14; a CCD 34 which receives the interference light LC and outputs a detection signal; Galvanometer mirrors 22 and 23 to scan the signal light LS in a main scanning direction and a sub-scanning direction; and a computer 40 forming tomographic images G1 to Gm along the main scanning direction at different positions of the sub-scanning direction. The Galvanometer mirrors 22 and 23 scan the signal light LS in a given direction crossing the main scanning direction, and the computer 40 forms a tomographic image for correction GR along the given direction to correct displacement of each topographic image Gi based on the tomographic image for correction GR.
摘要翻译：提供了即使在信号光的扫描期间物体移动时也可以形成高可靠性图像的光学图像测量装置。光学图像形成装置1包括：干涉仪，其将低相干光L0分解成信号光LS和参考光LR，并通过将由眼底反射的信号光LS与反射的参考光LR重叠而产生干涉光LC 通过参考反射镜14; CCD34，其接收干涉光LC并输出检测信号; 电流计镜22和23在主扫描方向和副扫描方向扫描信号光LS; 以及在副扫描方向的不同位置沿着主扫描方向形成断层图像G1〜Gm的计算机40。电流计反射镜22和23沿与主扫描方向相交的给定方向扫描信号光LS，并且计算机40沿着给定方向形成用于校正GR的断层图像，以校正基于断层图像的每个地形图像Gi的位移校正GR。

10. 发明授权

US08684528B2 Fundus analyzing appartus and fundus analyzing method 有权
标题翻译：眼底分析和眼底分析方法
公开(公告)号：US08684528B2
公开(公告)日：2014-04-01
申请号：US13387497
申请日：2010-07-14
申请人： Takashi Fujimura , Hiroyuki Aoki
发明人： Takashi Fujimura , Hiroyuki Aoki
IPC分类号： A61B3/12 , A61B3/10
CPC分类号： A61B3/12 , A61B3/1005 , A61B3/102 , G06T7/0012 , G06T2200/24 , G06T2207/10101 , G06T2207/30041
摘要： A fundus analyzing apparatus 1 performs OCT measurements of a fundus Ef and generates multiple tomographic images that each depict layer structures of the fundus Ef. Each formed tomographic image is stored in a storage 212. Based on the pixel values of the pixels of each tomographic image, the layer-region identifying part 233 identifies the layer region corresponding to the pigment layer of the retina. Based on the shape of the layer region, the curve calculator 234 obtains a convex standard curve in the direction of depth of the fundus Ef. Based on the layer region and the standard curve, a protrusion-region identifying part 235 identifies protrusion regions where the layer region protrudes in the opposite direction from the direction of depth of the fundus Ef. A morphological-information generating part 236 generates morphological information representing the morphology (number, size, distribution, etc.) of the protrusion regions.
摘要翻译：眼底分析装置1执行眼底Ef的OCT测量，并生成各自描绘眼底Ef的层结构的多个断层图像。每个形成的断层图像被存储在存储器212中。基于每个断层图像的像素的像素值，层区域识别部分233识别对应于视网膜的颜料层的层区域。基于层区域的形状，曲线计算器234获得在眼底Ef的深度方向上的凸标准曲线。基于层区域和标准曲线，突起区域识别部件235识别突起区域，其中层区域沿与眼底Ef的深度方向相反的方向突出。形态信息生成部236生成表示突起区域的形态（数量，大小，分布等）的形态信息。

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