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1. 发明申请

US20080072914A1 Bronchial Isolation Devices for Placement in Short Lumens 审中-公开
标题翻译：用于在短流明中放置的支气管隔离装置
公开(公告)号：US20080072914A1
公开(公告)日：2008-03-27
申请号：US11844700
申请日：2007-08-24
申请人： Michael Hendricksen , Antony Fields , Michael Barrett , Ronald Hundertmark , Alan Rapacki , Steve Wallace , Michael Regan , John McCutcheon
发明人： Michael Hendricksen , Antony Fields , Michael Barrett , Ronald Hundertmark , Alan Rapacki , Steve Wallace , Michael Regan , John McCutcheon
IPC分类号： A62B9/02 , A61F2/04
CPC分类号： A61B17/12168 , A61B17/12022 , A61B17/12036 , A61B17/12104 , A61B17/12172 , A61B2017/1205 , A61F2/04 , A61F2/24 , A61F2002/043
摘要： Methods and devices are adapted for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.
摘要翻译：方法和装置适于调节流入和流出患者肺部区域的流体流动，例如在呼吸过程中实现期望的流体流动到肺部区域，和/或诱导一个或多个肺部区域的塌陷。根据示例性程序，确定的肺部区域被靶向用于治疗。然后将目标肺区域支气管分离，以通过一个或多个将空气送入目标肺部区域的支气管通路来调节进入和/或离开目标肺区域的气流。

2. 发明申请

US20060020347A1 Implanted bronchial isolation devices and methods 审中-公开
公开(公告)号：US20060020347A1
公开(公告)日：2006-01-26
申请号：US11075633
申请日：2005-03-08
申请人： Michael Barrett , Michael Hendricksen , Alan Rapacki , Ronald Hundertmark , Jeffrey Dolin , Robert George , John McCutcheon , Antony Fields
发明人： Michael Barrett , Michael Hendricksen , Alan Rapacki , Ronald Hundertmark , Jeffrey Dolin , Robert George , John McCutcheon , Antony Fields
IPC分类号： A61F2/04
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/12172 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/86 , A61F2/91 , A61F2002/043 , A61F2230/0054
摘要： Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

3. 发明申请

US20050166925A1 Bronchial flow control devices and methods of use 有权
标题翻译：支气管流量控制装置及使用方法
公开(公告)号：US20050166925A1
公开(公告)日：2005-08-04
申请号：US11092123
申请日：2005-03-28
申请人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
发明人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
IPC分类号： A61B17/00 , A61B17/24 , A61F2/04 , A61F2/06 , A61F2/24 , A61M16/00 , A61M16/20 , A61M11/00
CPC分类号： A61F2/2412 , A61B2017/1205 , A61F2/04 , A61F2/06 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043 , A61F2002/9522 , Y10S128/912
摘要： Methods and systems for lung volume reduction of a patient are described. The methods include implanting a flow control device in a bronchial passageway of the lung. The flow control device regulates fluid flow through the bronchial passageway and includes a valve protector that at least partially surrounds a valve member. The valve protector has sufficient rigidity to maintain the shape of the valve member against compression.
摘要翻译：描述了患者肺容积减少的方法和系统。所述方法包括在肺的支气管通道中植入流量控制装置。流量控制装置调节通过支气管通道的流体流动并且包括至少部分地围绕阀构件的阀保护器。阀保护器具有足够的刚性以保持阀构件的形状不被压缩。

4. 发明申请

US20050145253A1 Bronchial flow control devices and methods of use 审中-公开
标题翻译：支气管流量控制装置及使用方法
公开(公告)号：US20050145253A1
公开(公告)日：2005-07-07
申请号：US11071850
申请日：2005-03-02
申请人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
发明人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
IPC分类号： A61B17/00 , A61B17/24 , A61F2/04 , A61F2/06 , A61F2/24 , A61M16/00 , A61M16/20 , A61M11/00 , A62B9/06
CPC分类号： A61F2/2412 , A61B2017/1205 , A61F2/04 , A61F2/06 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043 , A61F2002/9522 , Y10S128/912
摘要： Methods and systems for lung volume reduction of a patient are described. The methods include implanting a flow control device in a bronchial passageway of the lung. The flow control device regulates fluid flow through the bronchial passageway. A region of the lung is aspirated distal of the flow control device while the patient is inhaling.
摘要翻译：描述了患者肺容积减少的方法和系统。所述方法包括在肺的支气管通道中植入流量控制装置。流量控制装置调节通过支气管通道的流体流动。当患者正在吸入时，肺部的区域被吸入流量控制装置的远端。

5. 发明申请

US20070203396A1 Endoscopic Tool 审中-公开
标题翻译：内窥镜工具
公开(公告)号：US20070203396A1
公开(公告)日：2007-08-30
申请号：US11679635
申请日：2007-02-27
申请人： John McCutcheon , Antony Fields , Ronald Hundertmark , Michael Hendricksen , Michael Barrett , Alan Rapacki , Garrett Schwab
发明人： John McCutcheon , Antony Fields , Ronald Hundertmark , Michael Hendricksen , Michael Barrett , Alan Rapacki , Garrett Schwab
IPC分类号： A61B1/06
CPC分类号： A61B1/05 , A61B1/00082 , A61B1/00147 , A61B1/00179 , A61B1/00181 , A61B1/0051 , A61B1/2676 , A61B5/1076 , A61B18/02
摘要： Delivery system including endoscopes are described. In an embodiment, a delivery system includes a flexible, elongate endoscope extending along a longitudinal axis when the endoscope is straightened and a first lens located on the distal region. The first lens faces a direction transverse to the longitudinal axis. The first lens permits the endoscope to provide an image of anatomical structures that offset from the axis of the endoscope.
摘要翻译：描述包括内窥镜在内的输送系统。在一个实施例中，递送系统包括当内窥镜矫直时沿着纵向轴线延伸的柔性细长内窥镜和位于远侧区域上的第一透镜。第一透镜面向横向于纵轴的方向。第一透镜允许内窥镜提供从内窥镜的轴线偏移的解剖结构的图像。

6. 发明申请

US20050066974A1 Modification of lung region flow dynamics using flow control devices implanted in bronchial wall channels 审中-公开
标题翻译：使用植入支气管壁通道的流量控制装置修改肺区流动动力学
公开(公告)号：US20050066974A1
公开(公告)日：2005-03-31
申请号：US10448153
申请日：2003-05-28
申请人： Antony Fields , Michael Hendricksen , Ronald Hundertmark
发明人： Antony Fields , Michael Hendricksen , Ronald Hundertmark
IPC分类号： A61F2/04 , A61F2/06 , A61F2/24 , A62B9/06 , A61M16/00
CPC分类号： A61F2/2412 , A61F2/04 , A61F2/06 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043
摘要： A desired fluid flow dynamic to a lung region can be achieved by deploying various combinations of flow control devices and bronchial isolation devices in one or more bronchial passageways that communicate with the lung region. The flow control devices are implanted in channels that are formed in the walls of bronchial passageways of the lung. The flow control devices regulate fluid flow through the channels. The bronchial isolation devices are implanted in lumens of bronchial passageways that communicate with the lung region in order to regulate fluid flow to and from the lung region through the bronchial passageways.
摘要翻译：可以通过在与肺部区域连通的一个或多个支气管通道中布置流量控制装置和支气管隔离装置的各种组合来实现动态到肺部区域的期望流体流动。将流量控制装置植入形成在肺的支气管通道的壁中的通道中。流量控制装置调节通过通道的流体流动。支气管隔离装置被植入到与肺部区域连通的支气管通道的内腔中，以调节通过支气管通道的流入和流出肺部区域的流体。

7. 发明申请

US20060283462A1 Methods and devices for inducing collapse in lung regions fed by collateral pathways 审中-公开
标题翻译：通过旁路途径诱导肺部区域崩溃的方法和装置
公开(公告)号：US20060283462A1
公开(公告)日：2006-12-21
申请号：US11509871
申请日：2006-08-25
申请人： Antony Fields , Ronald Hundertmark , John McCutcheon
发明人： Antony Fields , Ronald Hundertmark , John McCutcheon
IPC分类号： A61M16/00 , A62B7/00
CPC分类号： F16K15/147 , A61B17/00491 , A61F2/04 , A61F2/06 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043
摘要： Disclosed are methods and devices for treating a patient's lung region. A catheter is deployed into the lung. The catheter is used to apply heat to a targeted lung region wherein the heat affects fluid flow within the targeted lung region.
摘要翻译：公开了用于治疗患者肺部区域的方法和装置。导管部署到肺部。该导管用于对目标肺部区域施加热量，其中热量影响目标肺部区域内的流体流动。

8. 发明申请

US20080027343A1 Methods and Devices for Lung Treatment 审中-公开
标题翻译：肺部治疗方法与装置
公开(公告)号：US20080027343A1
公开(公告)日：2008-01-31
申请号：US11696627
申请日：2007-04-04
申请人： Antony Fields , Ronald Hundertmark , John McCutcheon
发明人： Antony Fields , Ronald Hundertmark , John McCutcheon
IPC分类号： A61B5/08
CPC分类号： F16K15/147 , A61B17/00491 , A61F2/04 , A61F2/06 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043
摘要： A method of diagnosing collateral ventilation between regions of a lung includes the step of measuring at least one parameter associated with a target lung region while a catheter is positioned in the target lung region. A level of collateral fluid flow into the target lung region is detected based on the at least one parameter.
摘要翻译：诊断肺部区域之间的旁路通气的方法包括在导管定位在目标肺部区域时测量与目标肺区域相关联的至少一个参数的步骤。基于至少一个参数来检测流入目标肺区域的侧流体的水平。

9. 发明申请

US20060030863A1 Implanted bronchial isolation device delivery devices and methods 审中-公开
标题翻译：植入式支气管隔离装置及方法
公开(公告)号：US20060030863A1
公开(公告)日：2006-02-09
申请号：US11186293
申请日：2005-07-20
申请人： Antony Fields , John McCutcheon , Alan Rapacki
发明人： Antony Fields , John McCutcheon , Alan Rapacki
IPC分类号： A61F11/00
CPC分类号： A61B1/2676 , A61B1/0058 , A61B17/12104 , A61B2017/00292 , A61B2017/1205 , A61F2002/043
摘要： Disclosed is a delivery system for insertion into a lung. The delivery system includes an elongate endoscope having a proximal end and a distal end and defining an internal lumen. The endoscope is configured to articulate in one or more directions. The system further includes a catheter that includes an elongate shaft sized to be inserted through the internal lumen of the endoscope. The catheter has a shape that aids in the articulation of the distal end of the endoscope when the catheter is positioned inside the endoscope.
摘要翻译：公开了用于插入肺的递送系统。输送系统包括具有近端和远端并限定内腔的细长内窥镜。内窥镜构造成在一个或多个方向上铰接。该系统还包括导管，其包括细长轴，该细长轴的尺寸被插入穿过内窥镜的内腔。当导管位于内窥镜内部时，导管具有帮助内窥镜的远端铰接的形状。

10. 发明授权

US5437635A Tube flow limiter, safety flow clip, and tube pincher mechanism 失效
标题翻译：管流量限制器，安全流夹和管夹机构
公开(公告)号：US5437635A
公开(公告)日：1995-08-01
申请号：US167413
申请日：1993-12-14
申请人： Antony Fields , Terry Branson , David J. Harrison , Dana J. Owens , Aaron T. Raines , Edward G. Rasmussen
发明人： Antony Fields , Terry Branson , David J. Harrison , Dana J. Owens , Aaron T. Raines , Edward G. Rasmussen
IPC分类号： A61M5/168 , A61M39/28 , A61M31/00
CPC分类号： A61M39/287 , A61M5/16813 , A61M39/281 , Y10S128/12
摘要： A flow limiter mechanism for use with an infusion pump of the type operating upon a disposable cassette held by the infusion pump and having a flow tube connected to the cassette. The flow limiter includes a receiving channel located on the infusion pump adjacent to the disposable cassette held by the infusion pump. A tube pincher is operatively associated with the receiving channel to pinch the flow tube in a clamped position and mechanically retractable to an unclamped position to allow the flow tube to open. Electrical controls are connected for selectably operating the tube pincher from the clamped closed position to the unclamped opened position while the disposable cassette is held by the infusion pump. A flow clip is attached to the flow tube and is manually operable between opened and closed clipping positions prior to inserting the disposable cassette into the infusion pump. The flow tube and attached flow clip are prevented from being removed from the flow limiter mechanism unless the flow clip is in the closed clipping position.
摘要翻译：一种流量限制器机构，用于与由输注泵保持的一次性盒一起操作并具有连接到盒的流管的输液泵。流量限制器包括位于输液泵附近的接收通道，其与由输注泵保持的一次性盒相邻。管夹钳与接收通道可操作地相关联以将流管夹紧在夹紧位置，并机械地缩回至松开位置以允许流管打开。电气控制器连接用于可选择地操作管夹持器从夹紧的关闭位置到松开的打开位置，而一次性盒由输液泵保持。流动夹连接到流动管，并且在将一次性盒插入输注泵之前可手动地在打开和闭合的夹持位置之间操作。防止流管和连接的流动夹子从流量限制器机构移除，除非流动夹具处于闭合夹紧位置。

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