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1. 发明授权

US07699987B2 Stabilized formulation 失效
标题翻译：稳定配方
公开(公告)号：US07699987B2
公开(公告)日：2010-04-20
申请号：US11449476
申请日：2006-06-08
申请人： Anand C. Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai S. Srinivasan , Rajesh Srivastava
发明人： Anand C. Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai S. Srinivasan , Rajesh Srivastava
IPC分类号： B01D15/08
CPC分类号： C07D305/14 , A61K47/44 , B01D15/325 , B01J20/287
摘要： A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using this purified polyethoxylated castor oil enhance the stability of paclitaxel in such compositions.
摘要翻译：公开了一种稳定的抗癌药物和溶剂，如聚乙氧基化蓖麻油（cremophor）的药物组合物，其也含有适于人类给药的任何其它合适的增溶剂如脱水醇。使用该纯化的聚乙氧基化蓖麻油制备的组合物增强紫杉醇在这些组合物中的稳定性。

2. 发明申请

US20050016926A1 Stabilized formulation 审中-公开
标题翻译：稳定配方
公开(公告)号：US20050016926A1
公开(公告)日：2005-01-27
申请号：US10626501
申请日：2003-07-24
申请人： Anand Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai Srinivasan , Rajesh Srivastava
发明人： Anand Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai Srinivasan , Rajesh Srivastava
IPC分类号： A61K47/44 , B01D15/08 , B01D15/32
CPC分类号： C07D305/14 , A61K47/44 , B01D15/325 , B01J20/287
摘要： A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using this purified polyethoxylated castor oil enhance the stability of paclitaxel in such compositions.
摘要翻译：公开了一种稳定的抗癌药物和溶剂，如聚乙氧基化蓖麻油（cremophor）的药物组合物，其也含有适于人类给药的任何其它合适的增溶剂如脱水醇。使用该纯化的聚乙氧基化蓖麻油制备的组合物增强紫杉醇在这些组合物中的稳定性。

3. 发明申请

US20060226076A1 Stabilized formulation 失效
标题翻译：稳定配方
公开(公告)号：US20060226076A1
公开(公告)日：2006-10-12
申请号：US11449476
申请日：2006-06-08
申请人： Anand Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai Srinivasan , Rajesh Srivastava
发明人： Anand Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai Srinivasan , Rajesh Srivastava
IPC分类号： B01D15/08
CPC分类号： C07D305/14 , A61K47/44 , B01D15/325 , B01J20/287
摘要： A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using this purified polyethoxylated castor oil enhance the stability of paclitaxel in such compositions.
摘要翻译：公开了一种稳定的抗癌药物和溶剂，如聚乙氧基化蓖麻油（cremophor）的药物组合物，其也含有适于人类给药的任何其它合适的增溶剂如脱水醇。使用该纯化的聚乙氧基化蓖麻油制备的组合物增强紫杉醇在这些组合物中的稳定性。

4. 发明申请

US20060216360A1 Stable pharmaceutical compositions of platinum (II) antitumour agents 审中-公开
标题翻译：稳定的铂（II）抗肿瘤药物组合物
公开(公告)号：US20060216360A1
公开(公告)日：2006-09-28
申请号：US11245141
申请日：2005-10-06
申请人： Satish Upadhyay , Manoj Pananchukunnath , Dinesh Kumar , Ajeet Singh , Rama Mukherjee , Anand Burman
发明人： Satish Upadhyay , Manoj Pananchukunnath , Dinesh Kumar , Ajeet Singh , Rama Mukherjee , Anand Burman
IPC分类号： A61K33/24 , A61K31/282
CPC分类号： A61K33/24 , A61K9/0019 , A61K9/08 , A61K31/282 , A61K31/555
摘要： A pharmaceutical composition comprising a platinum (II) complex compound in n aqueous solvent. The pharmaceutical composition is prepared by the essential steps of: (i) adding a platinum (II) complex compound to an oxygen enriched aqueous solvent to obtain a solution; (ii) Sterilizing the solution (iii) Filling the sterilizedsolution of step (ii) into suitable containers; and (iv) Sealing the containers. The oxygen enriched aqueous solvent is obtained by purging or bubbling of a gas into an aqueous solvent for 30 to 150 minutes. A device for preparing the pharmaceutical composition is illustrated in FIG. 1. The composition is used for treatment of a human or an animal cancerous disease by the administration of pharmaceutical compositions of platinum (II) complex compounds as per the claim 1, to the human or animal in need of said treatment.
摘要翻译：一种包含在n水溶液中的铂（II）络合物化合物的药物组合物。药物组合物通过以下步骤制备：（i）向富氧水溶剂中加入铂（II）络合物，得到溶液; （ii）灭菌溶液（iii）将步骤（ii）的无菌溶液装入合适的容器中; 和（iv）密封容器。通过将气体吹扫或鼓泡到含水溶剂中30至150分钟来获得富氧水溶剂。用于制备药物组合物的装置在图1中示出。 1.通过将权利要求1的铂（II）配合物化合物的药物组合物给予需要所述治疗的人或动物，该组合物用于治疗人或动物癌性疾病。

5. 发明授权

US09769050B2 End-to-end datacenter performance control 有权
公开(公告)号：US09769050B2
公开(公告)日：2017-09-19
申请号：US14581595
申请日：2014-12-23
申请人： Andrew J. Herdrich , Patrick Connor , Dinesh Kumar , Alexander W. Min , Ravishankar Iyer , Daniel J. Dahle , Kapil Sood , Jeffrey B. Shaw
发明人： Andrew J. Herdrich , Patrick Connor , Dinesh Kumar , Alexander W. Min , Ravishankar Iyer , Daniel J. Dahle , Kapil Sood , Jeffrey B. Shaw
IPC分类号： G06F15/173 , H04L12/26 , H04L12/24 , G06F12/084 , G06F12/0811
CPC分类号： H04L43/50 , G06F12/0811 , G06F12/084 , G06F2212/152 , G06F2212/601 , H04L41/0896 , H04L41/5009 , H04L41/5025 , H04L41/5035 , H04L41/5096 , H04L43/16
摘要： In embodiments, apparatuses, methods and storage media (transitory and non-transitory) are described that are associated with end-to-end datacenter performance control. In various embodiments, an apparatus for computing may receive a datacenter performance target, determine an end-to-end datacenter performance level based at least in part on quality of service data collected from a plurality of nodes, and send a mitigation command based at least in part on a result of a comparison of the end-to-end datacenter performance level determined to the datacenter performance target. In various embodiments, the apparatus for computing may include one or more processors, a memory, a datacenter performance monitor to receive a datacenter performance target corresponding to a service level agreement, and a mitigation module to send a mitigation command based at least in part on a result of a comparison of an end-to-end datacenter performance level to a datacenter performance target.

6. 发明授权

US09736754B2 Data distribution to portable electronic devices 有权
公开(公告)号：US09736754B2
公开(公告)日：2017-08-15
申请号：US14527790
申请日：2014-10-30
申请人： Dinesh Kumar
发明人： Dinesh Kumar
IPC分类号： H04L12/28 , H04W4/00 , H04W40/04 , H04W4/02 , H04W84/18 , H04W76/02
CPC分类号： H04W40/04 , H04W4/02 , H04W76/14 , H04W84/18
摘要： Various embodiments of systems and methods for data distribution to portable electronic devices are described herein. Initially a data server receives a data download request from one or more portable electronic devices. Next the requested data is divided into a plurality of data portions. Next based on an-hoc network, a data-transfer route between the one or more portable electronic devices and a plurality of portable electronic devices connected to the data server are identified. The data server then forwards the plurality of data portions to the plurality of portable electronic devices connected to the data server. Finally, based on the identified data-transfer route, the requested data from the one or more portable electronic devices to the other portable electronic devices is transferred.

7. 发明申请

US20130029905A1 FORMULATION CONTAINING CURCUMINOIDS EXHIBITING ENHANCED BIOAVAILABILITY 有权
标题翻译：含有CURCUMINOID的配方展示增强的生物利用度
公开(公告)号：US20130029905A1
公开(公告)日：2013-01-31
申请号：US13360005
申请日：2012-01-27
申请人： Krishnakumar Illathu Madhavamenon , Abhilas Ravi , Dinesh Kumar , Balu Paulose Maliakel
发明人： Krishnakumar Illathu Madhavamenon , Abhilas Ravi , Dinesh Kumar , Balu Paulose Maliakel
IPC分类号： A61K38/16 , A61P3/02
CPC分类号： A61K36/48 , A61K31/121 , A61K47/36 , A61K2236/30 , A61K2300/00
摘要： The present invention relates to a formulation containing curcuminoids exhibiting enhanced in vivo bioavailability and resultant improved efficacy, said formulation comprising curcuminoids and a gel forming, non digestive and soluble dietary polysaccharide fiber galactomannan and proteins derived from fenugreek [Trigonella Foenum graecum]. The invention also relates to a process for producing the said formulation and extracting non-digestible soluble dietary polysaccharide fiber galacomannans containing proteins from fenugreek seeds.
摘要翻译：本发明涉及一种含有显示出增强的体内生物利用度和产生改善的功效的姜黄素的制剂，所述制剂包含姜黄素和凝胶形成，非消化和可溶性膳食多糖纤维半乳甘露聚糖和衍生自葫芦巴[Trigonella Foenum graecum]的蛋白质。本发明还涉及一种生产所述制剂并从葫芦巴种子中提取含有蛋白质的不可消化的可溶性膳食多糖纤维聚乳酸甘露聚糖的方法。

8. 发明授权

US07832114B2 Tracker holder assembly 有权
标题翻译：跟踪器支架组件
公开(公告)号：US07832114B2
公开(公告)日：2010-11-16
申请号：US11850482
申请日：2007-09-05
申请人： Jasjit S. Suri , Dinesh Kumar , Animesh Khemka
发明人： Jasjit S. Suri , Dinesh Kumar , Animesh Khemka
IPC分类号： A61B8/00
CPC分类号： A61B8/12 , A61B8/4218 , A61B8/4245
摘要： Provided herein are devices and methods for mounting variously configured medical imaging probes to a tracker assembly for imaging applications. In one aspect, a tracker assembly provides multiple degrees of freedom for positioning a probe relative to a patient and/or maintaining a probe in a desired location for imaging purposes. The tracker generates location information that may be utilized as frame of reference information for acquired images. In another aspect a holding device allows for interfacing/holding differently configured probes in a common orientation to a predetermined frame of reference.
摘要翻译：本文提供了用于将各种配置的医学成像探针安装到用于成像应用的跟踪器组件的装置和方法。在一个方面，跟踪器组件提供多个自由度，用于将探针相对于患者定位和/或将探针保持在期望的位置以用于成像目的。跟踪器生成可用作所获取图像的参考信息的位置信息。在另一方面，保持装置允许以与预定参考系相同的方向将不同配置的探针连接/保持。

9. 发明授权

US07634776B2 Multi-threaded processing design in architecture with multiple co-processors 有权
标题翻译：具有多个协处理器的多线程处理设计
公开(公告)号：US07634776B2
公开(公告)日：2009-12-15
申请号：US11127687
申请日：2005-05-12
申请人： Sankaranarayanan Parameswaran , Sriram Sethuraman , Manish Singhal , Dileep Kumar Tamia , Dinesh Kumar , Aditya Kulkarni , Murali Babu Muthukrishnan
发明人： Sankaranarayanan Parameswaran , Sriram Sethuraman , Manish Singhal , Dileep Kumar Tamia , Dinesh Kumar , Aditya Kulkarni , Murali Babu Muthukrishnan
IPC分类号： G06F9/46 , G06F9/30 , G06T1/20
CPC分类号： G06F15/7842 , H04N19/154 , H04N19/436 , H04N19/61 , H04N19/80
摘要： A method for designing a multi-threaded processing operation that includes, e.g., multimedia encoding/decoding, uses an architecture having multiple processors and optional hardware accelerators. The method includes the steps of: identifying a desired chronological sequence of processing stages for processing input data including identifying interdependencies of said processing stages; allotting each said processing sage to a processor; staggering the processing to accommodate the interdependencies; selecting a processing operation based on said allotting to arrive at a subset of possible pipelines that offer low average processing time; and, choosing one design pipeline from said subset to result in overall timing reduction to complete said processing operation. The invention provides a multi-threaded processing pipeline that is applicable in a System-on-Chip (SoC) using a DSP and shared resources such as DMA controller and on-chip memory, for increasing the throughput. The invention also provides an article which is programmed to execute the method.
摘要翻译：用于设计包括例如多媒体编码/解码的多线程处理操作的方法使用具有多个处理器和可选硬件加速器的架构。该方法包括以下步骤：识别用于处理输入数据的处理阶段的期望时间序列，包括识别所述处理阶段的相互依赖性; 将每个所述处理鼠标分配给处理器; 惊ering处理以适应相互依存关系; 基于所述分配来选择处理操作以得到提供较低平均处理时间的可能管线的子集; 并且从所述子集中选择一个设计流水线以产生总体时序减少以完成所述处理操作。本发明提供了一种多线程处理流水线，其可应用于使用DSP和诸如DMA控制器和片上存储器之类的共享资源的片上系统（SoC），以提高吞吐量。本发明还提供了一种被编程以执行该方法的物品。

10. 发明申请

US20090048515A1 BIOPSY PLANNING SYSTEM 审中-公开
标题翻译：生物计划系统
公开(公告)号：US20090048515A1
公开(公告)日：2009-02-19
申请号：US11838518
申请日：2007-08-14
申请人： Jasjit S. Suri , Dinesh Kumar , Yujun Guo , Ramkrishnan Narayanan
发明人： Jasjit S. Suri , Dinesh Kumar , Yujun Guo , Ramkrishnan Narayanan
IPC分类号： A61B10/02 , A61B8/13
CPC分类号： A61B8/12 , A61B10/02 , A61B2017/00274 , A61B2018/00547 , A61B2090/367
摘要： Guided biopsy is a commonly used method to remove suspicious tissues from an internal organ for pathological tests so that malignancy can be established. Provided herein are systems and methods (i.e., utilities) that allow for automated application of one or more predefined biopsy target plans to an acquired medical image including without limitation, an ultrasound prostate image. Due to different shapes and sizes of prostates as well as orientation of prostate with respect to an ultrasound probe during image, acquisition a simple prostate model (e.g., ellipse) with a fixed plan may not be sufficient. Accordingly, it has been determined that a deformable shape model with integrated biopsy target locations/sites may be fit to a prostate image to provide improved automated biopsy targeting.
摘要翻译：引导活检是一种常用的方法，用于从内部器官中清除可疑组织进行病理检查，以确定恶性。本文提供了允许将一个或多个预定义的活检目标计划自动应用于所获取的医学图像的系统和方法（即实用程序），包括但不限于超声前列腺图像。由于在图像期间由于前列腺的不同形状和尺寸以及相对于超声探头的前列腺的取向，所以采集具有固定计划的简单前列腺模型（例如椭圆）可能不足够。因此，已经确定具有集成活检目标位置/位点的可变形形状模型可以适合于前列腺图像以提供改进的自动活检靶向。

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