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1. 发明授权

US6031133A Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof 失效
标题翻译：多羟基，二烯基内酯及其模拟物的合成技术和中间体
公开(公告)号：US6031133A
公开(公告)日：2000-02-29
申请号：US21878
申请日：1998-02-11
申请人： Amos B. Smith, III , Yuping Qiu , Michael Kaufman , Hirokaza Arimoto , David R. Jones , Kaoru Kobayashi
发明人： Amos B. Smith, III , Yuping Qiu , Michael Kaufman , Hirokaza Arimoto , David R. Jones , Kaoru Kobayashi
IPC分类号： C07D303/16 , A61K31/047 , A61K31/12 , A61K31/27 , A61K31/336 , A61K31/351 , A61K31/366 , A61K31/422 , A61K31/427 , A61K31/5355 , A61K31/7028 , A61P35/00 , A61P37/06 , C07C239/06 , C07D263/22 , C07D309/10 , C07D309/30 , C07D309/32 , C07D319/06 , C07D413/06 , C07D413/12 , C07D417/06 , C07F7/18 , C07H23/00 , C07C233/04
CPC分类号： C07D413/12 , C07C239/06 , C07D263/22 , C07D309/30 , C07D319/06 , C07F7/1892
摘要： Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.
摘要翻译：提供了含内酯化合物如脱氧胆甾醇的合成方法，以及模拟其化学和/或生物活性的化合物，以及可用于其制备的方法和中间体。

2. 发明授权

US5789605A Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof 失效
公开(公告)号：US5789605A
公开(公告)日：1998-08-04
申请号：US759817
申请日：1996-12-03
申请人： Amos B. Smith, III , Yuping Qiu , Michael Kaufman , Hirokaza Arimoto , David R. Jones , Kaoru Kobayashi
发明人： Amos B. Smith, III , Yuping Qiu , Michael Kaufman , Hirokaza Arimoto , David R. Jones , Kaoru Kobayashi
IPC分类号： C07D303/16 , A61K31/047 , A61K31/12 , A61K31/27 , A61K31/336 , A61K31/351 , A61K31/366 , A61K31/422 , A61K31/427 , A61K31/5355 , A61K31/7028 , A61P35/00 , A61P37/06 , C07C239/06 , C07D263/22 , C07D309/10 , C07D309/30 , C07D309/32 , C07D319/06 , C07D413/06 , C07D413/12 , C07D417/06 , C07F7/18 , C07H23/00 , C07D407/06
CPC分类号： C07D413/12 , C07C239/06 , C07D263/22 , C07D309/30 , C07D319/06 , C07F7/1892
摘要： Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.

3. 发明授权

US6096904A Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives 失效
标题翻译：多羟基，二烯基内酯衍生物的合成技术和中间体
公开(公告)号：US6096904A
公开(公告)日：2000-08-01
申请号：US121551
申请日：1998-07-23
申请人： Amos B. Smith, III , Yuping Qiu , Michael Kaufman , Hirokazu Arimoto , David R. Jones , Kaoru Kobayashi , Thomas J. Beauchamp
发明人： Amos B. Smith, III , Yuping Qiu , Michael Kaufman , Hirokazu Arimoto , David R. Jones , Kaoru Kobayashi , Thomas J. Beauchamp
IPC分类号： C07D263/22 , A61K31/047 , A61K31/12 , A61K31/27 , A61K31/336 , A61K31/351 , A61K31/366 , A61K31/422 , A61K31/427 , A61K31/5355 , A61K31/7028 , A61P35/00 , A61P37/06 , C07C29/38 , C07C33/02 , C07C33/42 , C07C239/06 , C07C271/12 , C07D303/16 , C07D309/10 , C07D309/30 , C07D309/32 , C07D319/06 , C07D413/06 , C07D413/12 , C07D417/06 , C07F7/18 , C07F9/54 , C07H23/00 , C07F9/02
CPC分类号： C07C239/06 , C07D263/22 , C07D309/30 , C07D319/06 , C07D407/06 , C07D413/06 , C07D413/12 , C07F7/1856 , C07F7/1892 , Y02P20/55
摘要： Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.
摘要翻译：提供了含内酯化合物如脱氧胆甾醇的合成方法，以及模拟其化学和/或生物活性的化合物，以及可用于其制备的方法和中间体。

4. 发明申请

US20050065353A1 Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof 审中-公开
标题翻译：多羟基二烯基内酯的合成技术和中间体及其模拟物
公开(公告)号：US20050065353A1
公开(公告)日：2005-03-24
申请号：US10779049
申请日：2004-02-13
申请人： Amos Smith , Yuping Qin , Michael Kaufman , Hirokazu Arimoto , David Jones , Kaoru Kobayashi , Thomas Beauchamp
发明人： Amos Smith , Yuping Qin , Michael Kaufman , Hirokazu Arimoto , David Jones , Kaoru Kobayashi , Thomas Beauchamp
IPC分类号： C07C271/12 , C07D213/30 , C07D263/22 , C07D303/16 , C07D309/10 , C07D309/30 , C07D309/32 , C07D319/06 , C07D339/08 , C07D407/06 , C07D413/06 , C07D413/12 , C07D417/06 , C07F7/18 , C07F9/54
CPC分类号： C07C271/12 , C07B2200/07 , C07D213/30 , C07D263/22 , C07D303/16 , C07D309/10 , C07D309/30 , C07D309/32 , C07D319/06 , C07D339/08 , C07D407/06 , C07D413/06 , C07D413/12 , C07D417/06 , C07F7/1804 , C07F7/1892 , C07F9/5428 , C07F9/5442
摘要： Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.
摘要翻译：提供了可用于制备含内酯化合物如discodermolide的合成方法和中间体以及模拟discodermolide的化学或生物活性的化合物。

5. 发明申请

US20060033341A1 Waterwheel powered air delivery device 审中-公开
标题翻译：水轮动力空气输送装置
公开(公告)号：US20060033341A1
公开(公告)日：2006-02-16
申请号：US10917448
申请日：2004-08-13
申请人： Michael Kaufman
发明人： Michael Kaufman
IPC分类号： F03B13/00 , H02P9/04
CPC分类号： F03B7/00 , F01C11/006 , F04C18/16 , F04C23/005 , F04C23/02 , F04D25/04 , Y02E10/223 , Y02P70/525
摘要： The waterwheel powered air delivery device is a system for powering an air compressor, aerator, or other device that moves air from power produced by a waterwheel without the necessity of providing electricity from an outside power source or the intermediate production of electricity from the waterwheel. The waterwheel may be an overshot, undershot or sideshot waterwheel. The device being powered may be an air compressor, aerator, or other air delivery device having an air pump that may be of the diaphragm, piston, rotary vane, rotary screw or other type. Preferably the air produced by the waterwheel and air delivery device is used for aeration of wastewater, although the delivery device may be used for other purposes, e.g., ventilation, power, etc.
摘要翻译：水轮动力空气输送装置是用于为空气压缩机，曝气器或其他装置供电的系统，该装置从水轮产生的动力移动空气，而不需要从外部电源提供电力或从水轮中间产生电力。水车可能是一个过冲，下面或侧面的水车。被供电的装置可以是具有可以是隔膜，活塞，旋转叶片，旋转螺杆或其它类型的空气泵的空气压缩机，曝气器或其它空气输送装置。优选地，由水车和空气输送装置产生的空气用于废水的通风，尽管输送装置可用于其它目的，例如通风，动力等。

6. 发明授权

US08486124B2 Controlled protocol timer 有权
标题翻译：受控协议定时器
公开(公告)号：US08486124B2
公开(公告)日：2013-07-16
申请号：US11940852
申请日：2007-11-15
申请人： Steven Hendrix , Kenneth Oif , Michael Kaufman
发明人： Steven Hendrix , Kenneth Oif , Michael Kaufman
IPC分类号： A61N5/06
CPC分类号： A61N5/0616 , A61N2005/064 , A61N2005/0661
摘要： A phototherapy treatment dispensing device provides therapeutic light emissions treatments. The device provides additional means for controlling a patient's exposure to those treatments through a controlled protocol timer. The controlled protocol timer can provide for incremental exposure increases; monitors patient compliance with a treatment regimen; and reminds the patient when a treatment will soon be overdue.
摘要翻译：光疗治疗分配装置提供治疗性光排放治疗。该装置提供了通过受控协议定时器来控制患者对这些治疗的暴露的附加手段。受控协议定时器可以提供增量曝光增加; 监测患者对治疗方案的依从性; 并提醒患者治疗即将过期。

7. 发明申请

US20060074547A1 Method of operating a navigation system to report effects of updated portions of a geographic database 有权
标题翻译：操作导航系统以报告地理数据库的更新部分的效果的方法
公开(公告)号：US20060074547A1
公开(公告)日：2006-04-06
申请号：US10955523
申请日：2004-09-30
申请人： Michael Kaufman , Christian Hecht
发明人： Michael Kaufman , Christian Hecht
IPC分类号： G01C21/36
CPC分类号： G06F17/30241 , G01C21/32 , Y10S707/99953 , Y10S707/99954
摘要： A method for operating a navigation system that executes a navigation application software program to provide a navigation-related feature is provided. The method comprises identifying that the navigation application software program uses both updated geographic data and un-updated geographic data from a geographic database associated with said navigation system. The un-updated geographic data has an associated date or version different from the updated geographic data. The method further comprises providing a report indicating that an inconsistency between the updated geographic data and the un-updated geographic data may exist. The method may further include identifying the inconsistency between the updated geographic data and the un-updated geographic data.
摘要翻译：提供一种用于操作执行导航应用软件程序以提供导航相关特征的导航系统的方法。该方法包括识别导航应用软件程序使用来自与所述导航系统相关联的地理数据库的更新的地理数据和未更新的地理数据。未更新的地理数据具有与更新的地理数据不同的关联日期或版本。该方法还包括提供指示可能存在更新的地理数据与未更新地理数据之间的不一致性的报告。该方法还可以包括识别更新的地理数据与未更新的地理数据之间的不一致性。

8. 发明申请

US20050137263A1 N-(4 substituted phenyl)-anthranilic acid hydroxamate esters 失效
标题翻译： N-（4取代苯基） - 邻氨基苯甲酸异羟肟酸酯
公开(公告)号：US20050137263A1
公开(公告)日：2005-06-23
申请号：US11051142
申请日：2005-02-04
申请人： Gordon Rewcastle , Julie Spicer , Stephen Barrett , Michael Kaufman , Jared Milbank , Haile Tecle
发明人： Gordon Rewcastle , Julie Spicer , Stephen Barrett , Michael Kaufman , Jared Milbank , Haile Tecle
IPC分类号： A61P9/04 , A61K31/165 , A61K31/166 , A61K31/18 , A61K31/21 , A61K31/27 , A61K31/66 , A61P9/10 , A61P17/06 , A61P19/02 , A61P25/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07C229/58 , C07C233/65 , C07C237/28 , C07C259/10 , C07C311/45 , C07C317/36 , C07C323/36 , C07C323/39
CPC分类号： C07C317/36 , C07C259/10 , C07C323/36 , Y10S514/825
摘要： The present invention relates to oxygenated esters of 4-substituted-phenylamino benzhydroxamic acid derivatives, pharmaceutical compositions and methods of use thereof.
摘要翻译：本发明涉及4-取代苯基氨基苯并肟酸衍生物的氧化酯，药物组合物及其使用方法。

9. 发明授权

US5581241A Ultra-sensitive smoke detector 失效
标题翻译：超敏感检测仪
公开(公告)号：US5581241A
公开(公告)日：1996-12-03
申请号：US289659
申请日：1994-08-12
申请人： Michael Kaufman , Richard W. Thomas
发明人： Michael Kaufman , Richard W. Thomas
IPC分类号： G08B17/107 , G08B17/10
CPC分类号： G08B17/107 , G08B17/113
摘要： A smoke detector that operates on the principle of scattered light is disclosed that has the capability of an operating sensitivity that is tens of times greater than that of smoke detectors presently available. Plural light sources are used, their light rays directed radially toward the center of a cylindrical detector chamber having a mirrored wall that reflects light back toward the chamber's center, thereby to brightly illuminate a central detection zone. Scattered light from smoke in this zone is detectable by a photocell at right angles to the converging multiple light rays. To obtain highly improved stability of the light output that enables ultra-high sensitivity, the light sources are light-emitting diodes in series connection and they are driven by a very stable constant voltage source that also powers the photocell detector. This system gains impressive sensitivity while reducing nuisance alarms that have been a common problem regarding efforts to increase smoke detector sensitivity. Whereas the goal of this invention is to improve the public safety, improvements are presented in smoke collection also, whereby ambient air is quickly and efficiently brought to the detector cell itself using convection currents that are enhanced by the aerodynamic design of the housing surrounding the cell.
摘要翻译：公开了以散射光原理工作的烟雾探测器，其具有比当前可用的烟雾探测器的操作灵敏度高几十倍的能力。使用多个光源，它们的光线径向指向圆柱形检测器室的中心，该圆柱形检测器室具有将光反射回室的中心的镜面壁，从而明亮地照亮中央检测区。在该区域内来自烟雾的散射光可以通过与会聚的多个光线成直角的光电池检测。为了获得能够实现超高灵敏度的光输出的高度改进的稳定性，光源是串联连接的发光二极管，并且它们由也为光电池检测器供电的非常稳定的恒定电压源驱动。该系统获得令人印象深刻的灵敏度，同时减少了增加烟雾探测器灵敏度方面常见问题的烦扰报警。尽管本发明的目标是提高公共安全性，但是在烟气收集中也提出了改进，其中通过由围绕电池的壳体的空气动力学设计增强的对流电流将环境空气快速且有效地带到检测器单元本身。

10. 发明申请

US20120292427A1 COMBINATION STRAPPING PACKAGE AND DISPENSER 审中-公开
标题翻译：组合包装和分配器
公开(公告)号：US20120292427A1
公开(公告)日：2012-11-22
申请号：US13440532
申请日：2012-04-05
申请人： Michael Kaufman , Rolando Antonio , Jeffrey Hochleutner , Dennis Miller
发明人： Michael Kaufman , Rolando Antonio , Jeffrey Hochleutner , Dennis Miller
IPC分类号： B65H16/02
CPC分类号： B65D85/671 , Y02W90/14
摘要： Various embodiments of the present disclosure provide a combination strapping package and dispenser that includes a first strapping coil holding compartment and a second strapping coil holding compartment configured to be nested together and to define a coil receiving or holding area. The combination strapping package and dispenser is configured to hold a strapping coil during shipment from the manufacturer or distributor to the end user and additionally during the use of the strapping by the end user such that the end user does not need to remove the strapping coil from the combination strapping package and dispenser. In certain embodiments, the combination strapping package and dispenser of the present disclosure is configured for mid-range amounts of coil which are easier to transport and use, is compostable, and requires less cost to ship.
摘要翻译：本公开的各种实施例提供了一种组合捆扎包装和分配器，其包括第一捆扎线圈保持隔间和第二捆扎线圈保持隔间，其构造成嵌套在一起并限定线圈接收或保持区域。组合捆扎包装和分配器被配置为在从制造商或分销商运送到最终用户期间保持捆扎线圈，并且另外在由最终用户使用捆扎带期间，使得最终用户不需要将捆扎线圈从组合包装和分配器。在某些实施例中，本公开的组合捆扎包装和分配器被配置为容易运输和使用的中等量的线圈，是可堆肥的，并且需要更少的运输成本。

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