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1. 发明授权

US06502550B1 Gaseous fueled engine system and method 有权
标题翻译：气体发动机系统及方法
公开(公告)号：US06502550B1
公开(公告)日：2003-01-07
申请号：US09683702
申请日：2002-02-05
申请人： Allan J. Kotwicki , Siamak Hashemi , Steven Joseph Szwabowski , Woong-chul Yang , Yin Chen , Yong-Wha Kim
发明人： Allan J. Kotwicki , Siamak Hashemi , Steven Joseph Szwabowski , Woong-chul Yang , Yin Chen , Yong-Wha Kim
IPC分类号： F02P500
CPC分类号： F02D41/009 , F02D37/02 , F02P7/067
摘要： An ignition and fuel control system 10 of a vehicle 18 is provided including a controller 22. The controller 22 is electrically coupled to an ignition system 14, a fuel system 16, a crankshaft position sensor 32, and a camshaft position sensor 34. The crankshaft position sensor 32 senses a crankshaft position and generates a crankshaft position signal. A camshaft position sensor 34 senses a camshaft position and generates a camshaft position signal. The controller 22 determines a crankshaft position and a camshaft position in response to the crankshaft position signal and the camshaft position signal respectively. The controller 22 identifies a reference engine cylinder in response to the crankshaft position and the camshaft position and generates a synchronization value. The controller 22 also enables the ignition system 14 and the fuel system 16 in response to the synchronization value.
摘要翻译：车辆18的点燃和燃料控制系统10设置有控制器22.控制器22电连接到点火系统14，燃料系统16，曲轴位置传感器32和凸轮轴位置传感器34.曲轴位置传感器32感测曲轴位置并产生曲轴位置信号。凸轮轴位置传感器34感测凸轮轴位置并产生凸轮轴位置信号。控制器22分别响应于曲轴位置信号和凸轮轴位置信号来确定曲轴位置和凸轮轴位置。控制器22响应于曲轴位置和凸轮轴位置识别参考发动机气缸，并产生同步值。控制器22还能够响应于同步值启用点火系统14和燃料系统16。

2. 发明授权

US06738707B2 Cylinder air charge estimation system and method for internal combustion engine including exhaust gas recirculation 失效
标题翻译：包括排气再循环的内燃机的气缸空气充量估算系统和方法
公开(公告)号：US06738707B2
公开(公告)日：2004-05-18
申请号：US10003365
申请日：2001-11-15
申请人： Allan J. Kotwicki , Steven Joseph Szwabowski , Woong-chul Yang , Yin Chen
发明人： Allan J. Kotwicki , Steven Joseph Szwabowski , Woong-chul Yang , Yin Chen
IPC分类号： F02D4118
CPC分类号： F02D41/18 , F02D41/0072 , F02D41/32 , F02D2041/0067 , F02D2200/0402 , F02D2200/0414
摘要： A system (12) and method for determining the charged air mass in a cylinder (14) of an internal combustion engine (10) are provided. The system (12) includes an electronic control unit (ECU) (58) configured to determine a temperature of the combination of charged air and recirculated exhaust gas inducted into the cylinder (14). The ECU (58) is further configured to determine a total mass flow rate of the combination of inducted air and recirculated exhaust gas based on a pressure in an intake manifold (22) of the engine (10) and the previously determined temperature. Finally, the ECU (58) is configured to determine the mass of charged air in the cylinder (14) from the total mass flow rate.
摘要翻译：提供了一种用于确定内燃机（10）的气缸（14）中的带电气体质量的系统（12）和方法。系统（12）包括电子控制单元（ECU）（58），该电子控制单元（58）被配置为确定加入到气缸（14）中的带电空气和再循环废气的组合的温度。 ECU（58）还被配置为基于发动机（10）的进气歧管（22）中的压力和先前确定的温度来确定感应空气和再循环排气的组合的总质量流量。最后，ECU（58）构成为从总质量流量确定汽缸（14）中的带电空气的质量。

3. 发明申请

US20050273245A1 COMPRESSION RATIO MODE SELECTION LOGIC FOR AN INTERNAL COMBUSTION ENGINE HAVING DISCRETE VARIABLE COMPRESSION RATIO CONTROL MECHANISM 有权
标题翻译：具有差异压缩比例控制机制的内燃机的压缩比模式选择逻辑
公开(公告)号：US20050273245A1
公开(公告)日：2005-12-08
申请号：US10858800
申请日：2004-06-03
申请人： Yin Chen , Woong-chul Yang , William Dutcher , David Trumpy , In Yoo , Chris Glugla , Diana Brehob
发明人： Yin Chen , Woong-chul Yang , William Dutcher , David Trumpy , In Yoo , Chris Glugla , Diana Brehob
IPC分类号： F02B75/04 , F02D13/02 , F02D35/02 , F02D41/30 , G06F17/00 , G06F19/00 , G06G7/70
CPC分类号： F02D41/3076 , F02D13/0207 , F02D35/027 , Y02T10/18
摘要： A method and system for operating an internal combustion engine. The internal combustion engine is operable in a plurality of compression ratio operating modes. The method includes determining a relationship between a base engine threshold load where the high compression and low compression provide substantially the same engine fuel consumption and engine speed. The determined nominal relationship is modified by a factor, such factor being a function of a condition under which such engine is operating, to obtain a modified relationship. The modified relationship is a function of engine speed and the condition has an effect on knock generation in such engine. The modified relationship and engine speed are used in selecting one of the plurality of compression ratio operating modes for the engine. A hysteresis load as a function of engine speed is determined and applied to the determined hysteresis load to the modified relationship to inhibit switching oscillations between a pair of the plurality of compression ratio operating modes.
摘要翻译：一种用于操作内燃机的方法和系统。内燃机可以多个压缩比操作模式操作。该方法包括确定高压缩和低压缩提供基本相同的发动机燃料消耗和发动机转速之间的基本发动机阈值负荷之间的关系。所确定的标称关系由因子修改，这种因素是这种发动机运行的条件的函数，以获得修改的关系。改进的关系是发动机转速的函数，该条件对这种发动机的爆震产生有影响。改变的关系和发动机转速用于选择发动机的多个压缩比操作模式之一。确定作为发动机转速的函数的滞后负载并将其应用于所确定的滞后负载至修改关系，以禁止一对多个压缩比操作模式之间的开关振荡。

4. 发明授权

US06970781B1 Compression ratio mode selection logic for an internal combustion engine having discrete variable compression ratio control mechanism 有权
标题翻译：具有离散可变压缩比控制机构的内燃机的压缩比模式选择逻辑
公开(公告)号：US06970781B1
公开(公告)日：2005-11-29
申请号：US10858800
申请日：2004-06-03
申请人： Yin Chen , Woong-chul Yang , William R. Dutcher , David K. Trumpy , In Kwang Yoo , Chris P. Glugla , Diana Brehob
发明人： Yin Chen , Woong-chul Yang , William R. Dutcher , David K. Trumpy , In Kwang Yoo , Chris P. Glugla , Diana Brehob
IPC分类号： F02B75/04 , F02D13/02 , F02D35/02 , F02D41/30 , G06F17/00 , G06F19/00 , G06G7/70
CPC分类号： F02D41/3076 , F02D13/0207 , F02D35/027 , Y02T10/18
摘要： A method and system for operating an internal combustion engine. The internal combustion engine is operable in a plurality of compression ratio operating modes. The method includes determining a relationship between a base engine threshold load where the high compression and low compression provide substantially the same engine fuel consumption and engine speed. The determined nominal relationship is modified by a factor, such factor being a function of a condition under which such engine is operating, to obtain a modified relationship. The modified relationship is a function of engine speed and the condition has an effect on knock generation in such engine. The modified relationship and engine speed are used in selecting one of the plurality of compression ratio operating modes for the engine. A hysteresis load as a function of engine speed is determined and applied to the determined hysteresis load to the modified relationship to inhibit switching oscillations between a pair of the plurality of compression ratio operating modes.
摘要翻译：一种用于操作内燃机的方法和系统。内燃机可以多个压缩比操作模式操作。该方法包括确定高压缩和低压缩提供基本相同的发动机燃料消耗和发动机转速之间的基本发动机阈值负荷之间的关系。所确定的标称关系由因子修改，这种因素是这种发动机运行的条件的函数，以获得修改的关系。改进的关系是发动机转速的函数，该条件对这种发动机的爆震产生有影响。改变的关系和发动机转速用于选择发动机的多个压缩比操作模式之一。确定作为发动机转速的函数的滞后负载并将其应用于所确定的滞后负载至修改关系，以禁止一对多个压缩比操作模式之间的开关振荡。

5. 发明授权

US09018213B2 Alicyclic[c] benzopyrone derivatives and uses thereof 有权
标题翻译：脂环式[c]苯并吡喃酮衍生物及其用途
公开(公告)号：US09018213B2
公开(公告)日：2015-04-28
申请号：US14236208
申请日：2012-07-31
申请人： Guisen Zhang , Yin Chen , Xiangqing Xu , Xin Liu , Song Zhao , Bifeng Liu , Minquan Yu , Yinli Qiu
发明人： Guisen Zhang , Yin Chen , Xiangqing Xu , Xin Liu , Song Zhao , Bifeng Liu , Minquan Yu , Yinli Qiu
IPC分类号： A61K31/496 , A61K31/453 , A61K31/454 , C07D311/94 , C07D405/12 , C07D417/12 , C07D417/14 , C07D413/14 , C07D311/80 , C07D409/12
CPC分类号： C07D311/94 , A61K31/453 , A61K31/454 , A61K31/496 , C07D311/80 , C07D405/12 , C07D409/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Disclosed are alicyclic[c]benzopyrone derivatives and use thereof. The alicyclic[c]benzopyrone derivatives are compounds represented by formula I or their salts. The present compounds not only significantly improve high activity induced by MK-801, but also effectively improve clambering symptom induced by Apomorphine and do not cause EPS within effective dose. These in vitro targets and in vivo pharmacological models are closely related to diseases of the nervous system caused by dopamine dysfunction, especially schizophrenia. Therefore the present compounds can be used for the treatment of central nervous system diseases, especially schizophrenia. ED50 is lower and effect is stronger in two animal models i.e. high activity induced by MK-801 and clambering symptom induced by Apomorphine, while ED50 is higher and therapeutic index is greater in animal models of catalepsy.
摘要翻译：公开了脂环族[c]苯并吡喃酮衍生物及其用途。脂环式[c]苯并吡喃酮衍生物是由式I表示的化合物或其盐。本发明化合物不仅显着改善了MK-801诱导的高活性，而且有效地改善了阿扑吗啡引起的痉挛症状，不会有效剂量引起EPS。这些体外靶标和体内药理学模型与由多巴胺功能障碍，特别是精神分裂症引起的神经系统疾病密切相关。因此，本发明化合物可用于治疗中枢神经系统疾病，特别是精神分裂症。 ED50较低，两种动物模型中效果更强，即由MK-801诱导的高活性和阿扑吗啡引起的痉挛症状，而ED50较高，而在僵住症的动物模型中治疗指数更高。

6. 发明授权

US08828958B2 Single-stranded antimicrobial oligonucleotides and uses thereof 有权
标题翻译：单链抗体寡核苷酸及其用途
公开(公告)号：US08828958B2
公开(公告)日：2014-09-09
申请号：US11664052
申请日：2005-09-28
申请人： Yin Chen , Xin Xing Tan
发明人： Yin Chen , Xin Xing Tan
IPC分类号： C07H21/04 , C12N15/11 , C12N15/00
CPC分类号： C12N15/113 , C12N15/111 , C12N2310/11 , C12N2310/111 , C12N2310/16 , C12N2320/11 , C12N2320/30 , C12N2330/31 , C12N2330/50
摘要： The current invention is directed to oligonucleotide sequences isolated from a sequence designated rbl-1 [SEQ ID NO. 19] that either kill or inhibit growth, or prevent the production of endogenously expressed toxin, of microorganisms. These ssDNA sequences, identified through use of a screening method, appear to act as modulators of essential growth functions which may act at the level of triplex formation, antisense inhibition, or as aptamers that alter gene function. The sequences, referred to as minimum functional regions, or MFRs, are useful inter alia as therapeutic agents for treatment of sepsis and other pathologies caused by microorganisms such as sepsis and/or in which microorganisms are contributory agents.
摘要翻译：本发明涉及从命名为rbl-1 [SEQ ID NO.1]的序列分离的寡核苷酸序列。 19]可以杀死或抑制微生物的生长，或阻止生成内源性表达的毒素。通过使用筛选方法鉴定的这些ssDNA序列似乎可以作为必需生长功能的调节剂，其可以在三重形成，反义抑制水平或作为改变基因功能的适体的作用下起作用。称为最小功能区域或MFR的序列尤其可用作治疗败血症的治疗剂和由诸如败血症和/或其中微生物是贡献剂的微生物引起的其它病症。

7. 发明申请

US20140171442A1 ALICYCLIC[C] BENZOPYRONE DERIVATIVES AND USES THEREOF 有权
标题翻译： ALICYCLIC [C]苯并噻吩衍生物及其用途
公开(公告)号：US20140171442A1
公开(公告)日：2014-06-19
申请号：US14236208
申请日：2012-07-31
申请人： Guisen Zhang , Yin Chen , Xiangqing Xu , Xin Liu , Song Zhao , Bifeng Liu , Miquan Yu , Yinli Qiu
发明人： Guisen Zhang , Yin Chen , Xiangqing Xu , Xin Liu , Song Zhao , Bifeng Liu , Miquan Yu , Yinli Qiu
IPC分类号： C07D311/94 , C07D413/14 , C07D417/12 , C07D409/12
CPC分类号： C07D311/94 , A61K31/453 , A61K31/454 , A61K31/496 , C07D311/80 , C07D405/12 , C07D409/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Disclosed are alicyclic[c]benzopyrone derivatives and use thereof. The alicyclic[c]benzopyrone derivatives are compounds represented by formula I or their salts. The present compounds not only significantly improve high activity induced by MK-801, but also effectively improve clambering symptom induced by Apomorphine and do not cause EPS within effective dose. These in vitro targets and in vivo pharmacological models are closely related to diseases of the nervous system caused by dopamine dysfunction, especially schizophrenia. Therefore the present compounds can be used for the treatment of central nervous system diseases, especially schizophrenia. ED50 is lower and effect is stronger in two animal models i.e. high activity induced by MK-801 and clambering symptom induced by Apomorphine, while ED50 is higher and therapeutic index is greater in animal models of catalepsy.
摘要翻译：公开了脂环族[c]苯并吡喃酮衍生物及其用途。脂环式[c]苯并吡喃酮衍生物是由式I表示的化合物或其盐。本发明化合物不仅显着改善了MK-801诱导的高活性，而且有效地改善了阿扑吗啡引起的痉挛症状，不会有效剂量引起EPS。这些体外靶标和体内药理学模型与由多巴胺功能障碍，特别是精神分裂症引起的神经系统疾病密切相关。因此，本发明化合物可用于治疗中枢神经系统疾病，特别是精神分裂症。 ED50较低，两种动物模型中效果更强，即由MK-801诱导的高活性和阿扑吗啡引起的痉挛症状，而ED50较高，而在僵住症的动物模型中治疗指数更高。

8. 发明申请

US20140113911A1 BENZOPYRONE DERIVATIVE AND USE THEREOF 有权
标题翻译：苯并噻吩衍生物及其用途
公开(公告)号：US20140113911A1
公开(公告)日：2014-04-24
申请号：US14009581
申请日：2012-04-06
申请人： Guisen Zhang , Yin Chen , Xiangqing Xu , Bifeng Liu , Xin Liu , Song Zhao , Shicheng Liu , Minquan Yu , Heng Zhang , Xinghua Liu
发明人： Guisen Zhang , Yin Chen , Xiangqing Xu , Bifeng Liu , Xin Liu , Song Zhao , Shicheng Liu , Minquan Yu , Heng Zhang , Xinghua Liu
IPC分类号： C07D417/12 , C07D413/14
CPC分类号： C07D417/12 , A61K31/454 , A61K31/496 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/14
摘要： The present invention relates to the field of pharmaceutical chemistry, and in particular, to a benzopyrone derivative and a use thereof. The benzopyrone derivative is compound having a structure of formula (I) or a pharmaceutically acceptable salt thereof. It has been found by experiments that, this type of compounds is useful in prevention or treatment of neuropsychical diseases.
摘要翻译：本发明涉及药物化学领域，特别涉及苯并吡喃酮衍生物及其应用。苯并吡喃酮衍生物是具有式（I）结构的化合物或其药学上可接受的盐。通过实验发现，这种类型的化合物可用于预防或治疗神经精神疾病。

9. 发明申请

US20070040211A1 Nonvolatile memory device and method of forming the same 有权
标题翻译：非易失存储器件及其形成方法
公开(公告)号：US20070040211A1
公开(公告)日：2007-02-22
申请号：US11209145
申请日：2005-08-22
申请人： Shao Ku , Yin Chen , Wenpin Lu , Tahui Wang
发明人： Shao Ku , Yin Chen , Wenpin Lu , Tahui Wang
IPC分类号： H01L29/792
CPC分类号： H01L29/7923 , H01L29/1045
摘要： A multi-bit memory cell includes a substrate; a multi-bit charge-trapping cell over the substrate, the multi-bit charge-trapping cell having a first lateral side and a second lateral side; a source region in the substrate, a portion of the source region being under the first side of the multi-bit charge-trapping cell; a drain region in the substrate, a portion of the drain region being under the second side of the multi-bit charge-trapping cell; and a channel region in the substrate between the source region and the drain region. The channel region has one of a p-type doping and an n-type doping, and the doping is configured to provide a highest doping concentration near the central portion of the channel region.
摘要翻译：多位存储单元包括基板; 位于衬底上的多位电荷俘获电池，所述多位电荷俘获电池具有第一侧面和第二侧面; 源区域，源区域中的一部分位于多位电荷捕获单元的第一侧之下; 所述衬底中的漏极区域，所述漏极区域的一部分位于所述多位电荷俘获电池的第二侧的下方; 以及在源极区域和漏极区域之间的衬底中的沟道区域。沟道区具有p型掺杂和n型掺杂之一，并且掺杂被配置为在沟道区的中心部分附近提供最高的掺杂浓度。

10. 发明授权

US09329008B1 Low collateral damage kinetic energy projectile 有权
标题翻译：低附带损伤动能射弹
公开(公告)号：US09329008B1
公开(公告)日：2016-05-03
申请号：US14444301
申请日：2014-07-28
申请人： Steven Gilbert , Ahmed Hassan , Yin Chen , Anthony Vella
发明人： Steven Gilbert , Ahmed Hassan , Yin Chen , Anthony Vella
IPC分类号： F42B12/02 , F42B12/74 , F42B14/06
CPC分类号： F42B12/02 , F42B10/48 , F42B12/06 , F42B12/74 , F42B14/06
摘要： A low collateral damage, kinetic energy penetrator has multiple segments that are mechanically locked together by centrifugal force generated by penetrator spin. When the penetrator spin decreases below a minimum value, the segments separate and fall to the ground with non-lethal kinetic energy.
摘要翻译：低附加损伤，动能穿透器具有通过穿透器旋转产生的离心力机械地锁定在一起的多个段。当穿透器旋转减小到最小值以下时，分段以非致死动能分离并落到地面。

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