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1. 发明申请

US20100310656A1 Immunotherapy and prevention of autoimmune hepatitis 审中-公开
标题翻译：免疫治疗和预防自身免疫性肝炎
公开(公告)号：US20100310656A1
公开(公告)日：2010-12-09
申请号：US12662663
申请日：2010-04-27
申请人： Aldar S. Bourinbaiar , Vichai Jirathitikal
发明人： Aldar S. Bourinbaiar , Vichai Jirathitikal
IPC分类号： A61K39/29 , C07K14/00 , A61K9/00 , A61K39/12 , A61K35/12 , A61K39/00 , A61P31/12 , A61P31/00
CPC分类号： C07K14/005 , A61K9/2054 , A61K39/0008 , A61K39/001 , A61K39/12 , A61K39/29 , A61K39/292 , A61K2039/542 , A61K2039/55588 , C12N2730/10134 , C12N2770/32422 , C12N2770/32434
摘要： The invention is within the field of immunology and microbiology, more specifically the field of virology and is related to immunotherapy and prophylaxis of hepatitis and autoimmune diseases. The composition useful for these purposes is disclosed, including the methods of making and using said composition.
摘要翻译：本发明属于免疫学和微生物学领域，更具体地涉及病毒学领域，涉及免疫治疗和预防肝炎和自身免疫性疾病。公开了用于这些目的的组合物，包括制备和使用所述组合物的方法。

2. 发明申请

US20110171267A1 ANTI-FUNGAL COMPOSITION 审中-公开
标题翻译：抗真菌组合物
公开(公告)号：US20110171267A1
公开(公告)日：2011-07-14
申请号：US13014431
申请日：2011-01-26
申请人： Aldar S. Bourinbaiar , Vichai Jirathitikal
发明人： Aldar S. Bourinbaiar , Vichai Jirathitikal
IPC分类号： A61K39/00 , A61P37/04
CPC分类号： A61K39/0002 , A61K2039/521 , Y02A50/41 , Y02A50/489
摘要： A multivalent fungal vaccine comprising one or more heat-inactivated fungal antigens, wherein at least one fungal antigen is effective in producing an immune response in a host when said vaccine is administered orally at a dose that is sufficient for preventing or treating the fungal disease in said host. Also described are methods for making and using an orally available anti-fungal vaccine.
摘要翻译：包含一种或多种热灭活的真菌抗原的多价真菌疫苗，其中当所述疫苗以足以预防或治疗真菌病的剂量口服给药时，至少一种真菌抗原在宿主中产生免疫应答是有效的主持人说。还描述了制备和使用口服可用的抗真菌疫苗的方法。

3. 发明授权

US5811390A Use of beta HCG for the control of retroviral infection 失效
标题翻译：使用βHCG控制逆转录病毒感染
公开(公告)号：US5811390A
公开(公告)日：1998-09-22
申请号：US517755
申请日：1995-08-22
申请人： Aldar S. Bourinbaiar
发明人： Aldar S. Bourinbaiar
IPC分类号： A61K38/24 , A61K38/16 , C07K14/59
CPC分类号： A61K38/24
摘要： Described is a method for inhibiting the growth and/or replication of human immunodeficiency virus (HIV) in human patients. The invention relates to the unexpected activity of human chorionic gonadotropin (hCG) and in particular, to the beta chain of hCG (beta hCG) in controlling a human immunodeficiency virus (HIV) infection and other virus-related immunodeficiency disorders. The invention comprises administering an anti-HIV effective amount of beta hCG to an asymptomatic individual with an HIV infection, including an individual presenting the symptoms of AIDS.
摘要翻译：描述了一种抑制人类免疫缺陷病毒（HIV）在人类患者中的生长和/或复制的方法。本发明涉及人绒毛膜促性腺激素（hCG）的意想不到的活性，特别涉及控制人类免疫缺陷病毒（HIV）感染和其他病毒相关免疫缺陷病症的hCG（βhCG）的β链。本发明包括向具有HIV感染的无症状个体施用抗HIV有效量的βhCG，包括呈现艾滋病症状的个体。

4. 发明授权

US5552382A Gramicidin as a spermicide against sexual transmission of HIV 失效
标题翻译：杀草胺作为抗艾滋病毒性传播的杀精剂
公开(公告)号：US5552382A
公开(公告)日：1996-09-03
申请号：US348482
申请日：1994-12-02
申请人： Aldar S. Bourinbaiar
发明人： Aldar S. Bourinbaiar
IPC分类号： A61K38/12 , A61K38/00
CPC分类号： A61K38/12
摘要： The invention relates to the use of gramicidin as an active ingredient of a spermicide with virucidal activity against human immunodeficiency virus (HIV)--a causative agent of a sexually transmitted disease--AIDS.
摘要翻译：本发明涉及使用短杆菌肽作为对人体免疫缺陷病毒（HIV）具有杀病毒活性的杀精剂的活性成分，这是一种性传播疾病 - 艾滋病的致病因子。

5. 发明授权

US6001808A Method of treating herpes virus infections with spermostatic gramicidin 失效
标题翻译：用止血片短杆菌肽治疗疱疹病毒感染的方法
公开(公告)号：US6001808A
公开(公告)日：1999-12-14
申请号：US912113
申请日：1997-08-15
申请人： Aldar S. Bourinbaiar
发明人： Aldar S. Bourinbaiar
IPC分类号： A61K38/08 , A61P31/12 , A61K38/00
CPC分类号： A61K38/08
摘要： The present invention relates to a method of using antibiotic gramicidin for the therapy and prevention of herpes virus infections. Gramicidin is also useful in suppressing sperm motility without affecting its viability and may thus be used as an active ingredient of topical contraceptive formulations either alone or in combination with chelating agents such as EDTA or salts thereof.
摘要翻译：本发明涉及使用抗生素短杆菌肽来治疗和预防疱疹病毒感染的方法。杀菌剂也可用于抑制精子活力而不影响其活力，因此可单独或与螯合剂如EDTA或其盐组合用作局部避孕制剂的活性成分。

6. 发明授权

US5837729A Methods for treating and preventing HIV infection using acetaminophen and derivatives thereof 失效
标题翻译：使用对乙酰氨基酚及其衍生物治疗和预防艾滋病毒感染的方法
公开(公告)号：US5837729A
公开(公告)日：1998-11-17
申请号：US638098
申请日：1996-04-26
申请人： Aldar S. Bourinbaiar
发明人： Aldar S. Bourinbaiar
IPC分类号： A61K31/167 , A61K31/245 , A61K31/24
CPC分类号： A61K31/245 , A61K31/167 , Y10S514/934
摘要： The present invention relates to the use of acetaminophen (Tylenol) and derivatives thereof which can be used to inhibit the growth, replication and elaboration of the human immunodeficiency virus (HIV). The present invention comprises in vitro as well as in vivo methods for the prevention and/or treatment of HIV infections and acquired immune deficiency syndrome (AIDS), at doses of acetaminophen or its derivatives which are effective to inhibit the replication, growth and/or elaboration of HIV.
摘要翻译：本发明涉及可用于抑制人免疫缺陷病毒（HIV）的生长，复制和制备的对乙酰氨基酚（Tylenol）及其衍生物的用途。本发明包括在对乙酰氨基酚或其衍生物的剂量下体外和体内用于预防和/或治疗HIV感染和获得性免疫缺陷综合征（AIDS）的方法，其有效抑制复制，生长和/或阐述艾滋病毒。

7. 发明授权

US5541212A Use of cimetidine for the control of retrovirus infections 失效
标题翻译：西咪替丁用于控制逆转录病毒感染
公开(公告)号：US5541212A
公开(公告)日：1996-07-30
申请号：US230064
申请日：1994-04-21
申请人： Aldar S. Bourinbaiar
发明人： Aldar S. Bourinbaiar
IPC分类号： A61K31/4164 , A61K31/415
CPC分类号： A61K31/4164
摘要： The invention relates to histamine H2-receptor antagonists such as cimetidine and related compounds such as ranitidine and famotidine that can be used for controlling human immunodeficiency virus (HIV) infection. The preferred agent is cimetidine. The invention comprises a method in vitro as well as in vivo for controlling, i.e., prevention and/or treatment, of HIV infection, associated with the development of acquired immune deficiency syndrome (AIDS), at pharmacological doses of these drugs commonly used for the treatment of gastrointestinal ulcers. The method is based on inhibiting HIV in vitro or on the administration to a host that has been exposed to HIV prior to diagnosis or has been diagnosed as having an HIV infection, of an amount of a H2 antagonist which is sufficient to exert an anti-HIV effect for a sufficient period of time.
摘要翻译：本发明涉及组胺H2受体拮抗剂如西咪替丁和相关化合物如雷尼替丁和法莫替丁，可用于控制人类免疫缺陷病毒（HIV）感染。优选的药剂是西咪替丁。本发明包括体外和体内用于控制，即预防和/或治疗与所获得的免疫缺陷综合征（AIDS）发展有关的HIV感染的方法，所述药物通常用于这些药物的药理学剂量治疗胃肠道溃疡。该方法基于在体外抑制HIV或在诊断之前暴露于HIV或被诊断患有HIV感染的宿主施用一定量的足以产生抗HIV的H 2拮抗剂，艾滋病毒影响足够的时间。

8. 发明授权

US06331610B1 Method for treating AIDS and HIV infection using select peptides from the beta subunit of human chorionic gonadotropin 失效
标题翻译：使用人绒毛膜促性腺激素β亚单位的选择肽治疗艾滋病和艾滋病毒感染的方法
公开(公告)号：US06331610B1
公开(公告)日：2001-12-18
申请号：US08908371
申请日：1997-08-07
申请人： Aldar S. Bourinbaiar
发明人： Aldar S. Bourinbaiar
IPC分类号： A61K3800
CPC分类号： A61K38/24 , C07K14/59
摘要： The present invention relates to select peptides of the carboxy terminal and aminoterminal portion of the beta unit of hCG and pharmaceutically acceptable derivatives thereof that can be used for controlling retroviral, e.g., human immunodeficiency virus (BV infections. The invention comprises a method in vitro as well as in vivo for prevention and/or treatment of acquired immune deficiency syndrome (AIDS) at pharmacological doses of beta hCG-derived peptides and pharmaceutically acceptable derivatives thereof which are sufficient to exert an anti-HIV effect for a sufficient period of time.
摘要翻译：本发明涉及可用于控制逆转录病毒（例如人类免疫缺陷病毒）（BV感染）的hCG的β单元的羧基末端和氨基末端部分的肽及其药学上可接受的衍生物，本发明包括体外方法以及用于预防和/或治疗获得性免疫缺陷综合征（AIDS）的药物剂量的βhCG衍生肽及其药学上可接受的衍生物，其足以在足够的时间内发挥抗HIV作用。

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