专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20130274237A1 COMPOSITION INCLUDING CHLOROPHYLL A AS AN ACTIVE INGREDIENT FOR PREVENTING AND TREATING TH2-MEDIATED IMMUNOLOGICAL DISEASES 审中-公开
标题翻译：作为预防和治疗TH2介导的免疫疾病的活性成分的氯林定量组合物
公开(公告)号：US20130274237A1
公开(公告)日：2013-10-17
申请号：US13882715
申请日：2010-09-14
申请人： Yong-Chul Kim , Zee Yong Park
发明人： Yong-Chul Kim , Zee Yong Park
IPC分类号： A61K31/555
CPC分类号： A61K31/555
摘要： The present invention relates to a composition including chlorophyll a as an active ingredient for preventing and treating Th2-mediated immunological diseases. The composition of the present invention is very effective for preventing and treating atopic dermatitis which is one of the Th2-mediated immunological diseases. Chlorophyll a is a natural ingredient used to treat atopic dermatitis and is advantageous in that it causes absolutely no side effects in humans. Further, the composition of the present invention may be applied as a medical composition including chlorophyll a, which has preventive and therapeutic effects for atopic dermatitis, as a food composition, as a cosmetic composition, and for various other products using chlorophyll a, and has excellent marketability.
摘要翻译：本发明涉及包含叶绿素a作为预防和治疗Th2介导的免疫疾病的活性成分的组合物。本发明的组合物对于预防和治疗Th2介导的免疫疾病之一的特应性皮炎是非常有效的。叶绿素a是用于治疗特应性皮炎的天然成分，其优点在于它在人体中绝对没有副作用。此外，本发明的组合物可以作为包含对特应性皮炎具有预防和治疗作用的叶绿素a，作为食品组合物的化妆品组合物以及使用叶绿素a的各种其它产品的药物组合物应用，并具有优良的市场性。

2. 发明申请

US20120321635A1 Composition Containing Inhibitors of the Expression or Activity of SH3RF2 for Preventing or Treating Cancer 有权
标题翻译：含有抑制SH3RF2表达或抑制活性的组合物用于预防或治疗癌症
公开(公告)号：US20120321635A1
公开(公告)日：2012-12-20
申请号：US13574055
申请日：2011-01-07
申请人： Kyung Chan Park , Young Il Yeom , Tae Woo Kim , Zee-Yong Park , Yun Kyung Kang , Suk-Jin Yang , Byung-Jung Choi , Dong Chul Lee , Hyun Ahm Shon , Hyang-Sook Yoo
发明人： Kyung Chan Park , Young Il Yeom , Tae Woo Kim , Zee-Yong Park , Yun Kyung Kang , Suk-Jin Yang , Byung-Jung Choi , Dong Chul Lee , Hyun Ahm Shon , Hyang-Sook Yoo
IPC分类号： A61K39/395 , A61K31/713 , A61K31/7088 , A61K38/02 , C07K16/18 , C07H21/04 , C07K2/00 , G01N33/574 , G01N21/64 , C12Q1/68 , G01N33/573 , C12Q1/02 , A61P35/00 , C07H21/02
CPC分类号： A61K31/7088 , A61K31/7105 , C12N15/113 , C12N2310/14
摘要： The present invention relates to a composition comprising an inhibitor of the expression or activity of SH3 domain containing ring finger 2 (SH3RF2) for preventing or treating cancers. More specifically, since the SH3RF2 protein, of which the expression level increases in various cancer tissues, binds to PAK4, which is a cancer-associated gene, to regulate an apoptosis inhibitory function of the PAK4 protein by ubiquitination activity of SH3RF2 RING domain, cancer cells, in which the expression of SH3RF2 is inhibited, sensitively respond to the induction of apoptosis to promote apoptosis and reduce in vivo tumorigenicity, such that the inhibitor of the expression or activity of SHRF2 can be useful as a composition for preventing or treating cancers.
摘要翻译：本发明涉及包含用于预防或治疗癌症的含有SH3结构域的SH3结构域（SH3RF2）的表达或活性抑制剂的组合物。更具体地说，由于在各种癌组织中表达水平升高的SH3RF2蛋白与作为癌相关基因的PAK4结合以通过SH3RF2 RING结构域的泛素化活性调节PAK4蛋白的凋亡抑制功能，癌症其中SH3RF2的表达被抑制的细胞对凋亡的诱导敏感应答以促进凋亡并降低体内致瘤性，使得SHRF2的表达或活性的抑制剂可用作预防或治疗癌症的组合物。

3. 发明申请

US20100113766A1 Methods for Preparing Chlorophyll a and Chlorin e6 有权
标题翻译：叶绿素a和氯in e6的制备方法
公开(公告)号：US20100113766A1
公开(公告)日：2010-05-06
申请号：US12513225
申请日：2007-05-03
申请人： Yong-Chul Kim , Zee Yong Park , Hyo Jun Kim
发明人： Yong-Chul Kim , Zee Yong Park , Hyo Jun Kim
IPC分类号： C09B47/00
CPC分类号： C12P17/182
摘要： The present invention relates to a method for preparing chlorophyll-a and chlorin e6. This invention extracts chlorophyll-a by use of undisrupted chlorella cells themselves, thereby preparing chlorin e6 from the chlorophyll-a extract. The high contents of chlorophyll-a may be obtained by the pretreatment procedure of chlorella cells themselves selected in this invention. The present method is performed according to relatively simple procedures, and is suitable in the mass production of chlorin e6.
摘要翻译：本发明涉及一种叶绿素a和二氢卟酚e6的制备方法。本发明通过使用未破坏的小球藻细胞本身提取叶绿素a，从而从叶绿素a提取物中制备二氢卟酚e6。通过本发明中选择的小球藻细胞的预处理程序可以获得高含量的叶绿素-α。本方法按照相对简单的程序进行，适用于大量生产二氢卟酚e6。

4. 发明授权

US08809295B2 Composition containing inhibitors of the expression or activity of SH3RF2 for preventing or treating cancer 有权
标题翻译：含有SH3RF2表达或活性抑制剂的组合物，用于预防或治疗癌症
公开(公告)号：US08809295B2
公开(公告)日：2014-08-19
申请号：US13574055
申请日：2011-01-07
申请人： Kyung Chan Park , Young Il Yeom , Tae Woo Kim , Zee-Yong Park , Yun Kyung Kang , Suk-Jin Yang , Byung-Jung Choi , Dong Chul Lee , Hyun Ahm Shon , Hyang-Sook Yoo
发明人： Kyung Chan Park , Young Il Yeom , Tae Woo Kim , Zee-Yong Park , Yun Kyung Kang , Suk-Jin Yang , Byung-Jung Choi , Dong Chul Lee , Hyun Ahm Shon , Hyang-Sook Yoo
IPC分类号： C12N15/11 , C12N15/113 , A61K31/7105 , A61K31/7088
CPC分类号： A61K31/7088 , A61K31/7105 , C12N15/113 , C12N2310/14
摘要： The present invention relates to a composition comprising an inhibitor of the expression or activity of SH3 domain containing ring finger 2 (SH3RF2) for preventing or treating cancers. More specifically, since the SH3RF2 protein, of which the expression level increases in various cancer tissues, binds to PAK4, which is a cancer-associated gene, to regulate an apoptosis inhibitory function of the PAK4 protein by ubiquitination activity of SH3RF2 RING domain, cancer cells, in which the expression of SH3RF2 is inhibited, sensitively respond to the induction of apoptosis to promote apoptosis and reduce in vivo tumorigenicity, such that the inhibitor of the expression or activity of SHRF2 can be useful as a composition for preventing or treating cancers.
摘要翻译：本发明涉及包含用于预防或治疗癌症的含有SH3结构域的SH3结构域（SH3RF2）的表达或活性抑制剂的组合物。更具体地说，由于在各种癌组织中表达水平升高的SH3RF2蛋白与作为癌相关基因的PAK4结合以通过SH3RF2 RING结构域的泛素化活性调节PAK4蛋白的凋亡抑制功能，癌症其中SH3RF2的表达被抑制的细胞对凋亡的诱导敏感应答以促进凋亡并降低体内致瘤性，使得SHRF2的表达或活性的抑制剂可用作预防或治疗癌症的组合物。

5. 发明授权

US08349335B2 Methods for preparing chlorophyll a and chlorin e6 有权
标题翻译：叶绿素a和二氢卟酚e6的制备方法
公开(公告)号：US08349335B2
公开(公告)日：2013-01-08
申请号：US12513225
申请日：2007-05-03
申请人： Yong Chul Kim , Zee Yong Park , Hyo Jun Kim
发明人： Yong Chul Kim , Zee Yong Park , Hyo Jun Kim
IPC分类号： A01N65/00 , A61K36/02 , C12N1/12 , C07B47/00 , C07D487/22
CPC分类号： C12P17/182
摘要： The present invention relates to a method for preparing chlorophyll-a and chlorin e6. This invention extracts chlorophyll-a by use of undisrupted chlorella cells themselves, thereby preparing chlorin e6 from the chlorophyll-a extract. The high contents of chlorophyll-a may be obtained by the pretreatment procedure of chlorella cells themselves selected in this invention. The present method is performed according to relatively simple procedures, and is suitable in the mass production of chlorin e6.
摘要翻译：本发明涉及一种叶绿素a和二氢卟酚e6的制备方法。本发明通过使用未破坏的小球藻细胞本身提取叶绿素-α，从而从叶绿素a提取物中制备二氢卟酚e6。通过本发明中选择的小球藻细胞的预处理程序可以获得高含量的叶绿素-α。本方法按照相对简单的程序进行，适用于大量生产二氢卟酚e6。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式