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1. 发明授权

US5106955A Process for preparation of antibody conjugates 失效
标题翻译：制备抗体的方法
公开(公告)号：US5106955A
公开(公告)日：1992-04-21
申请号：US304987
申请日：1988-11-23
申请人： Noriaki Endo , Yumiko Takeda , Yoshinori Kato , Takeshi Hara
发明人： Noriaki Endo , Yumiko Takeda , Yoshinori Kato , Takeshi Hara
IPC分类号： G01N33/531 , A61K39/395 , A61K45/00 , A61K47/48 , A61P35/00 , C07K1/107 , C07K1/113 , C07K14/00 , C07K16/00
CPC分类号： A61K47/48715 , A61K39/395 , A61K47/48369 , A61K47/48707
摘要： A process for production of antibody conjugates which comprises modification of a part of the amino groups in an antibody or its fragment whose antigen-binding activity is lowered by the modification of its amino groups, with a reversible modifier for protein amino groups, reaction of the antibody or its fragment with a substance bearing a group reactive with the amino group and removal of the residues of the reversible modifier from the amino groups and, when necessary, the residues of the substance bearing a group reactive with the amino group in case they are introduced onto groups other than amino groups. The process according to the present invention gives antibody conjugates with retention of antigen-binding activity and these conjugates have a possibility of being used in affinity chromatography or as a diagnostic agent or a drug for cancer therapy.

2. 发明授权

US08955934B2 Fluid ejecting apparatus and fluid ejecting method 有权
标题翻译：流体喷射装置和流体喷射方法
公开(公告)号：US08955934B2
公开(公告)日：2015-02-17
申请号：US12833713
申请日：2010-07-09
申请人： Bunji Ishimoto , Yumiko Takeda
发明人： Bunji Ishimoto , Yumiko Takeda
IPC分类号： B41J29/38 , B41J2/21
CPC分类号： B41J2/2114 , B41J2/2117
摘要： A fluid ejecting apparatus includes first and second rows of nozzles for ejecting first and second fluids respectively, a mechanism that transports the medium in the row direction, a mechanism that moves the nozzle rows in a direction intersecting the direction of the rows, and a controller that repeats an image formation operation while the medium is transported and the rows of nozzles moved. After forming a first image using the first row of nozzles, a second image is formed on the first image using the second row of nozzles in another image formation operation. For normal image formation, the second nozzles are set further downstream in the nozzle row direction than the first nozzles, and for image formation on a lower end portion of the medium, the second nozzles are set further upstream in the nozzle row direction than they are during normal image formation.
摘要翻译：流体喷射装置包括分别喷射第一和第二流体的第一排和第二排喷嘴，沿行方向输送介质的机构，沿与行方向相交的方向移动喷嘴列的机构，以及控制器在传送介质并移动喷嘴列的同时，重复图像形成操作。在使用第一排喷嘴形成第一图像之后，在另一图像形成操作中，使用第二排喷嘴在第一图像上形成第二图像。对于正常的图像形成，第二喷嘴设置在喷嘴行方向上比第一喷嘴更深的下游，并且对于在介质的下端部分上的图像形成，第二喷嘴在喷嘴行方向上比在其上方更靠近在正常成像期间。

3. 发明申请

US20130016160A1 LIQUID EJECTING APPARATUS AND LIQUID EJECTING METHOD 有权
标题翻译：液体喷射装置和液体喷射方法
公开(公告)号：US20130016160A1
公开(公告)日：2013-01-17
申请号：US13622068
申请日：2012-09-18
申请人： Bunji Ishimoto , Yumiko Takeda
发明人： Bunji Ishimoto , Yumiko Takeda
IPC分类号： B41J2/135
CPC分类号： B41J2/1433 , B41J2/2114
摘要： A liquid ejecting apparatus includes: a first nozzle row in which first nozzles ejecting a first liquid are arranged in a predetermined direction; a second nozzle row in which second nozzles ejecting a second liquid are arranged in the predetermined direction; a movement mechanism moving the first and second nozzle rows in a movement direction intersecting the predetermined direction relative to a medium; a transport mechanism transporting the medium in the predetermined direction relative to the first and second nozzle rows; and a control unit repeating an image forming operation of ejecting the liquids from the first and second nozzles while moving the first and second nozzle rows in the movement direction by the movement mechanism and a transport operation of transporting the medium in the predetermined direction relative to the first and second nozzle rows by the transport mechanism.
摘要翻译：液体喷射装置包括：第一喷嘴列，其中喷射第一液体的第一喷嘴沿预定方向布置; 第二喷嘴列，其中喷射第二液体的第二喷嘴沿预定方向布置; 移动机构，使第一喷嘴列和第二喷嘴列相对于介质与预定方向相交的运动方向移动; 传送机构，相对于第一和第二喷嘴列沿预定方向传送介质; 以及控制单元，其重复进行从第一和第二喷嘴喷射液体的图像形成操作，同时通过移动机构沿移动方向移动第一和第二喷嘴列，以及相对于所述移动机构沿预定方向传送介质的传送操作第一和第二喷嘴行由传送机构。

4. 发明申请

US20110025744A1 LIQUID EJECTING APPARATUS AND LIQUID EJECTING METHOD 有权
标题翻译：液体喷射装置和液体喷射方法
公开(公告)号：US20110025744A1
公开(公告)日：2011-02-03
申请号：US12814854
申请日：2010-06-14
申请人： Bunji Ishimoto , Yumiko Takeda
发明人： Bunji Ishimoto , Yumiko Takeda
IPC分类号： B41J29/38
CPC分类号： B41J2/1433 , B41J2/2114
摘要： A liquid ejecting apparatus includes: a first nozzle row in which first nozzles ejecting a first liquid are arranged in a predetermined direction; a second nozzle row in which second nozzles ejecting a second liquid are arranged in the predetermined direction; a movement mechanism moving the first and second nozzle rows in a movement direction intersecting the predetermined direction relative to a medium; a transport mechanism transporting the medium in the predetermined direction relative to the first and second nozzle rows; and a control unit repeating an image forming operation of ejecting the liquids from the first and second nozzles while moving the first and second nozzle rows in the movement direction by the movement mechanism and a transport operation of transporting the medium in the predetermined direction relative to the first and second nozzle rows by the transport mechanism.
摘要翻译：液体喷射装置包括：第一喷嘴列，其中喷射第一液体的第一喷嘴沿预定方向布置; 第二喷嘴列，其中喷射第二液体的第二喷嘴沿预定方向布置; 移动机构，使第一喷嘴列和第二喷嘴列相对于介质与预定方向相交的运动方向移动; 传送机构，相对于第一和第二喷嘴列沿预定方向传送介质; 以及控制单元，其重复进行从第一和第二喷嘴喷射液体的图像形成操作，同时通过移动机构沿移动方向移动第一和第二喷嘴列，以及相对于所述移动机构沿预定方向传送介质的传送操作第一和第二喷嘴行由传送机构。

5. 发明申请

US20080121544A1 Sheet-Like Article Storage Container 有权
标题翻译：片状物品储存容器
公开(公告)号：US20080121544A1
公开(公告)日：2008-05-29
申请号：US11814328
申请日：2005-06-06
申请人： Yoshihiro Hagihara , Yuriko Matsumoto , Yumiko Takeda , Yoshinobu Saito , Tetsuo Nishina
发明人： Yoshihiro Hagihara , Yuriko Matsumoto , Yumiko Takeda , Yoshinobu Saito , Tetsuo Nishina
IPC分类号： B65D85/62
CPC分类号： B65D83/087
摘要： The present invention provides a sheet member container from which sheet members housed in a stacked state can be taken out reliably and in which occurrence of a wrinkle in the next sheet member in returning operation of sheet feeding means is reduced. The sheet member container has a container body 1 having a top face opening for containing stacked sheet members 10; a lid member 15 for openably/closably closing with respect to a top face opening 6 of the container body 1; and sheet feeding means 30 provided for the lid member 15 for feeding the sheet members 10 one by one from the top via a slot 25 formed in either one of the container body 1 or the lid member 15. The sheet member container has bending means A for bending the sheet members 10 housed in the container body 1 in a direction orthogonal to a feeding direction of the sheet members.
摘要翻译：本发明提供了一种片状部件容器，能够可靠地取出容纳在堆叠状态的片状部件，并且在片材进给装置的返回操作中在下一个片状部件中出现褶皱。片材容器具有容器主体1，其具有用于容纳堆叠的片状构件10的顶面开口; 用于相对于容器主体1的顶面开口6可开闭地关闭的盖构件15; 以及用于盖构件15的片材进给装置30，用于经由形成在容器主体1或盖构件15中的任一个中的狭槽25从顶部一个接一个地供给片构件10。片材容器具有弯曲装置A，用于弯曲容纳在容器主体1中的片材10在与片材的进给方向正交的方向上。

6. 发明授权

US5517610A Portrait drawing apparatus having facial expression designating function 失效
标题翻译：具有面部表情指定功能的纵向绘图装置
公开(公告)号：US5517610A
公开(公告)日：1996-05-14
申请号：US434330
申请日：1995-05-02
申请人： Yumiko Takeda , Satoru Makino , Mina Kawai
发明人： Yumiko Takeda , Satoru Makino , Mina Kawai
IPC分类号： G06T11/00 , G06F15/00 , G06F12/00
CPC分类号： G06T11/00 , G06Q99/00
摘要： A portrait drawing apparatus having a facial part data table comprising data about the correspondence of component facial parts of portraits to different facial expressions. When it is desired to modify the previously drawn portrait of the same person with a different facial expression, the facial parts corresponding to the desired facial expression are determined to replace the applicable old facial parts. Substituting the newly selected facial parts for the old allows the portrait with the designated facial expression to be drawn with ease.
摘要翻译：一种具有面部部分数据表的纵向绘制装置，其包括关于肖像的组件面部部分对不同面部表情的对应关系的数据。当希望用不同的面部表情修改同一人的先前绘制的肖像时，确定与期望的面部表情相对应的面部部分以替换可适用的旧脸部部分。将新选择的面部部分替换为旧，可以容易地绘制具有指定的面部表情的肖像。

7. 发明授权

US07841488B2 Sheet-like article storage container 有权
标题翻译：片状物品储存容器
公开(公告)号：US07841488B2
公开(公告)日：2010-11-30
申请号：US11814328
申请日：2005-06-06
申请人： Yoshihiro Hagihara , Yuriko Matsumoto , Yumiko Takeda , Yoshinobu Saito , Tetsuo Nishina
发明人： Yoshihiro Hagihara , Yuriko Matsumoto , Yumiko Takeda , Yoshinobu Saito , Tetsuo Nishina
IPC分类号： B65D85/62
CPC分类号： B65D83/087
摘要： A sheet member container from which sheet members housed in a stacked state can be taken out reliably and in which occurrence of a wrinkle in a next sheet member in a returning operation of a sheet feeder is reduced. The sheet member container includes a container body having a top face opening for containing stacked sheet members; a lid member for openably/closably closing with respect to a top face opening of the container body; and a sheet feeding mechanism provided for the lid member for feeding the sheet members one by one from the top via a slot formed in either one of the container body or the lid member. The sheet member container includes a mechanism for bending the sheet members housed in the container body in a direction orthogonal to a feeding direction of the sheet members.
摘要翻译：可以可靠地取出片状部件容纳在堆叠状态的片材容器，并且在片材进给器的返回操作中在下一个片状部件中出现皱纹。片材容器包括容器主体，其具有用于容纳堆叠片材的顶面开口; 盖构件，用于相对于容器主体的顶面开口可开闭地关闭; 以及片材进给机构，用于盖部件，用于经由形成在容器主体或盖部件中的任一个中的狭槽从顶部一个接一个地供给片状部件。片材容器包括用于沿与片材的进给方向正交的方向弯曲容纳在容器主体中的片材的机构。

8. 发明授权

US06295480B1 Applicability determination device for quilt design and memory medium storing a controlling program thereof 失效
标题翻译：用于被设计的适用性确定装置和存储其控制程序的存储介质
公开(公告)号：US06295480B1
公开(公告)日：2001-09-25
申请号：US09514585
申请日：2000-02-28
申请人： Yoshihisa Kayanaka , Ryohei Komiya , Takeshi Kawaguchi , Toshihiko Ikeda , Michiyo Amano , Yumiko Takeda , Satoru Makino
发明人： Yoshihisa Kayanaka , Ryohei Komiya , Takeshi Kawaguchi , Toshihiko Ikeda , Michiyo Amano , Yumiko Takeda , Satoru Makino
IPC分类号： G06F1900
CPC分类号： D05B19/02 , D05B19/08
摘要： A CPU selects a line segment, whose both endpoints constructing a part of a quilt design are on a periphery, and then selects a line segment, which separates a piece from the quilt design on a piece-by-piece basis so that the separated piece will not have a line segment to become a separation line, from the selected line segments, after separation. When the line segment can be selected, a piece is separated from the quilt design at the selected line segment on a piece-by-piece basis. Then, the CPU determines that the quilt design, whose one piece has been separated, is the object to be determined, and separates pieces from the quilt design on a piece-by-piece basis. When all line segments are used for the separation, an applicability determination flag is set, because all pieces in the quilt design are separated into pieces on the piece-by-piece basis.
摘要翻译： CPU选择一个线段，其两端构成被子设计的一部分在外围，然后选择一个线段，该线段将一块与被套设计逐个分离，以便分离的片段分离后不会有线段成为分隔线，与选定的线段相分离。当可以选择线段时，将一块与所选线段上的被子设计逐一分离。然后，CPU确定被分离的一件被子设计是待确定的对象，并逐个分离与裁剪设计的部分。当所有线段用于分离时，设置适用性确定标志，因为被子设计中的所有片段被逐个分割成块。

9. 发明授权

US06215506B1 Portrait drawing apparatus 失效
标题翻译：肖像画设备
公开(公告)号：US06215506B1
公开(公告)日：2001-04-10
申请号：US08069365
申请日：1993-06-01
申请人： Satoru Makino , Yumiko Takeda , Mina Kawai
发明人： Satoru Makino , Yumiko Takeda , Mina Kawai
IPC分类号： G06F1500
CPC分类号： G06T11/60 , Y10S707/99945 , Y10S707/99948
摘要： A portrait drawing apparatus for storing for each facial part a plurality of attributes thereof (race, sex, age-group, specific shape such as snub or aquiline for nose, etc.) and for allowing the facial part candidates selected as per the designated attributes to be displayed preferentially over the candidates having other attributes so that the operator will determine the appropriate facial parts with ease and combine them into a portrait in the shortest possible time. The apparatus comprises an image display unit, an input unit and a memory unit that stores programs and data, i.e., a facial part attribute table, facial part pattern data and facial part candidate tables. The facial part attribute table includes pattern numbers, facial part patterns, attributes, and address pointers pointing to the facial part pattern data.
摘要翻译：一种纵向绘制装置，用于为每个面部部分存储多个属性（种族，性别，年龄组，诸如鼻子的缓冲或特征等的特定形状），并且允许根据指定属性选择的面部部分候选优先显示在具有其他属性的候选者上，以便操作者容易地确定适当的面部部分，并将它们在最短的时间内组合成肖像。该装置包括存储程序和数据的图像显示单元，输入单元和存储单元，即面部部件属性表，面部部件图形数据和面部部件候选表。面部部分属性表包括指向面部部位图形数据的图案编号，面部部位图案，属性和地址指针。

10. 发明授权

US09301908B2 Detergent composition 有权
标题翻译：洗涤剂组成
公开(公告)号：US09301908B2
公开(公告)日：2016-04-05
申请号：US14237380
申请日：2012-08-28
申请人： Tomoko Toda , Uhei Tamura , Yoshinobu Saito , Yumiko Takeda , Saori Kajita , Tetsuo Nishina
发明人： Tomoko Toda , Uhei Tamura , Yoshinobu Saito , Yumiko Takeda , Saori Kajita , Tetsuo Nishina
IPC分类号： A61K8/44 , A61K8/39 , A61Q19/10 , C11D3/48 , C11D1/94 , A61K8/49 , A61Q17/00 , A61K8/33 , A61Q5/02 , A61K8/898 , C11D1/72 , C11D1/90
CPC分类号： A61K8/44 , A61K8/33 , A61K8/39 , A61K8/4946 , A61K8/898 , A61Q5/02 , A61Q17/005 , A61Q19/10 , C11D1/72 , C11D1/90 , C11D1/94 , C11D3/48
摘要： A detergent composition excellent in an antimicrobial activity. Thus, a detergent composition of the present invention is characterized by including: an imidazolinium betaine-based amphoteric surfactant; and 0.5 to 10% by mass of PEG-1 lauryl glycol represented by the following formula (I): wherein, m and n each represent the number of moles of added ethylene oxide and the average of m+n is 1. Also, the detergent composition preferably includes an ingredient having a microstatic effect or microcidal effect selected from divalent glycols, hinokitiol, trichlorocarbanilide, and benzalkonium chloride.
摘要翻译：抗菌活性优异的洗涤剂组合物。因此，本发明的洗涤剂组合物的特征在于包括：基于咪唑啉甜菜碱的两性表面活性剂; 和0.5〜10质量％的由下式（I）表示的PEG-1月桂基二醇：其中，m和n各自表示环氧乙烷的加成摩尔数，m + n的平均值为1.另外，洗涤剂组合物优选包括具有选自二元二醇，桧醇，三氯碳酰苯胺和苯扎氯铵的微静电效应或杀微生物作用的成分。

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