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1. 发明申请

US20060036311A1 Stent and process for producing the same 失效
标题翻译：支架及其制造方法
公开(公告)号：US20060036311A1
公开(公告)日：2006-02-16
申请号：US10525016
申请日：2003-08-20
申请人： Yasuhide Nakayama , Shogo Nishi , Yasushi Nemoto , Yoshihiro Okamoto
发明人： Yasuhide Nakayama , Shogo Nishi , Yasushi Nemoto , Yoshihiro Okamoto
IPC分类号： A61F2/90 , A61F2/82
CPC分类号： A61F2/90 , A61F2002/072 , A61F2210/0004 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/00 , B29C41/042 , B29C41/14 , B29C41/20 , B29C41/22 , B29K2995/0059 , B29K2995/006 , B29L2031/753
摘要： A stent comprising a tubular stent matrix of which diameter is extendable and a flexible polymer layer covering the stent matrix. The polymer layer is closely attached to and covers the entire surface of the stent matrix. Since the flexible polymer layer closely covers the entire surface of the stent matrix not only the outer periphery of the stent matrix, the stent has no problem of causing allergic to metal, stimulus of tissues due to metal, and rust development. Since the inner periphery of the stent is a flat and smooth surface covered by the polymer layer without convexes and concaves, the formation of thrombus can be inhibited well. There is no problem of drift between the polymer layer and the stent matrix, thereby maintaining the positional relationship between the stent matrix and the polymer layer before and after the expansion of the stent.
摘要翻译：一种支架，其包括直径可延伸的管状支架基质和覆盖支架基质的柔性聚合物层。聚合物层紧密地附着并覆盖支架基质的整个表面。由于柔性聚合物层不仅覆盖支架基体的整个表面，而且不仅支架基体的外周，所以支架不会引起金属过敏，金属刺激，以及生锈。由于支架的内周是由没有凸起和凹陷的聚合物层覆盖的平坦且光滑的表面，因此可以良好地抑制血栓的形成。在聚合物层和支架基体之间不存在漂移问题，从而在支架膨胀前后维持支架基体与聚合物层之间的位置关系。

2. 发明授权

US08591782B2 Process for producing stent 失效
标题翻译：生产支架的方法
公开(公告)号：US08591782B2
公开(公告)日：2013-11-26
申请号：US10525016
申请日：2003-08-20
申请人： Yasuhide Nakayama , Shogo Nishi , Yasushi Nemoto , Yoshihiro Okamoto
发明人： Yasuhide Nakayama , Shogo Nishi , Yasushi Nemoto , Yoshihiro Okamoto
IPC分类号： B29C37/02
CPC分类号： A61F2/90 , A61F2002/072 , A61F2210/0004 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/00 , B29C41/042 , B29C41/14 , B29C41/20 , B29C41/22 , B29K2995/0059 , B29K2995/006 , B29L2031/753
摘要： A stent comprising a tubular stent matrix of which diameter is extendable and a flexible polymer layer covering the stent matrix. The polymer layer is closely attached to and covers the entire surface of the stent matrix. Since the flexible polymer layer closely covers the entire surface of the stent matrix not only the outer periphery of the stent matrix, the stent has no problem of causing allergic to metal, stimulus of tissues due to metal, and rust development. Since the inner periphery of the stent is a flat and smooth surface covered by the polymer layer without convexes and concaves, the formation of thrombus can be inhibited well. There is no problem of drift between the polymer layer and the stent matrix, thereby maintaining the positional relationship between the stent matrix and the polymer layer before and after the expansion of the stent.
摘要翻译：一种支架，其包括直径可延伸的管状支架基质和覆盖支架基质的柔性聚合物层。聚合物层紧密地附着并覆盖支架基质的整个表面。由于柔性聚合物层不仅覆盖支架基体的整个表面，而且不仅支架基体的外周，所以支架不会引起金属过敏，金属刺激，以及生锈。由于支架的内周是由没有凸起和凹陷的聚合物层覆盖的平坦且光滑的表面，因此可以良好地抑制血栓的形成。在聚合物层和支架基体之间不存在漂移问题，从而在支架膨胀前后维持支架基体与聚合物层之间的位置关系。

3. 发明授权

US07063733B2 Filter member 失效
标题翻译：过滤器
公开(公告)号：US07063733B2
公开(公告)日：2006-06-20
申请号：US10481055
申请日：2002-06-21
申请人： Hisashi Mori , Tadashi Kuwahara , Yasushi Nemoto
发明人： Hisashi Mori , Tadashi Kuwahara , Yasushi Nemoto
IPC分类号： B01D53/04
CPC分类号： B01D46/521 , A61L9/014 , A61L9/16 , B01D39/083 , B01D39/1623 , B01D46/0038 , B01D46/10 , B01D2239/0407 , B01D2239/045 , B01D2239/0478 , B01D2239/0618 , B01D2239/0622 , B01D2239/0627 , B01D2239/065 , B01D2239/0668 , B01D2239/0681 , B01D2239/069 , B01D2239/1233 , B01D2239/1291 , B01D2275/10 , B60H2003/0691
摘要： A filter member which comprises one layer of deodorizing filter 1, which is composed of a reticulated filter substrate and a deodorizing agent adhering to the surface of its skeletons, and one or two layers of dust collecting filter 2a and 2b laminated on any one side or both sides thereof, with the resulting laminate being pleated.
摘要翻译：一种过滤构件，其包括一层除臭过滤器1，其由网状过滤器基材和粘附到其骨架表面的除臭剂组成，以及层叠在任何一个上的一层或两层集尘过滤器2a和2b 侧面或两侧，所得到的层压材料被打褶。

4. 发明申请

US20070198053A1 Cuff member 审中-公开
标题翻译：袖口会员
公开(公告)号：US20070198053A1
公开(公告)日：2007-08-23
申请号：US11506815
申请日：2006-08-21
申请人： Eisuke Tatsumi , Toshihide Mizuno , Yoshiyuki Taenaka , Yasushi Nemoto , Yoshihiro Okamoto , Hare Tazawa
发明人： Eisuke Tatsumi , Toshihide Mizuno , Yoshiyuki Taenaka , Yasushi Nemoto , Yoshihiro Okamoto , Hare Tazawa
IPC分类号： A61B17/00
CPC分类号： A61M25/02 , A61L31/146 , A61M2025/0266 , A61M2025/0293
摘要： A cuff member that enhances the invasion and engraftment of cells from subcutaneous tissue of a living body and robustly adheres to the subcutaneous tissue through the vascularization of capillary vessels, and can consequently isolate a wound from the outside, block exacerbating factors such as bacterial infection during healing, inhibit the downgrowth, and reduce infection problems including tunnel infection. A cuff member 2 includes a flange 3 and a tubular portion 4. The cuff member 2 includes a three-dimensional network open-cell porous structure, which is formed of a thermoplastic resin or a thermosetting resin and has an average pore size of 100 to 1000 μm and an apparent density of 0.01 to 0.5 g/cm3. A pad 5 overlies the flange 3. A tube 6 passes through the pad 5 and the flange 3.
摘要翻译：一种增强从生物体皮下组织侵入和移植细胞的囊袋，通过毛细血管的血管化牢固地粘附在皮下组织上，从而将伤口从外部分离出来，阻止诸如细菌感染的加重因素愈合，抑制下丘，减少感染问题，包括隧道感染。套箍构件2包括凸缘3和管状部分4。袖带构件2包括由热塑性树脂或热固性树脂形成的平均孔径为100〜1000μm，表观密度为0.01〜0.5g / cm 3的三维网状开孔多孔结构体， SUP> 3 。垫5叠在凸缘3上。管6穿过垫5和凸缘3。

5. 发明授权

US5279856A Hydrophilic porous membrane, method of manufacturing the same and liquid filter using same 失效
标题翻译：亲水性多孔膜，其制造方法和使用其的液体过滤器
公开(公告)号：US5279856A
公开(公告)日：1994-01-18
申请号：US996158
申请日：1992-12-23
申请人： Noriyuki Koyama , Shinsuke Yokomachi , Yasushi Nemoto , Makoto Ohnishi
发明人： Noriyuki Koyama , Shinsuke Yokomachi , Yasushi Nemoto , Makoto Ohnishi
IPC分类号： B01D67/00
CPC分类号： B01D67/0088 , B01D67/0093
摘要： A hydrophilic porous membrane is obtained by covering porous membrane substrate with a non-ionic, amino-acid-based or non-ionic fluorine-based surface active agent. For the covering, the porous membrane substrate is immersed in a solution containing the surface active agent and then drying the membrane substrate. A different hydrophilic porous membrane is obtained by providing the surfaces of a porous membrane substrate and inner pore surfaces with a polar group and then covering the membrane substrate with a hydrophilic polymer film. For this covering, after introduction of the polar group to the surfaces of the porous membrane substrate and inner pore surfaces, the membrane substrate is immersed in a solution containing a hydrophilic substance and then dried. In a liquid filter using any of these hydrophilic porous membrane the porous membrane is disposed in a housing such as to divide the housing inner space into two sub-spaces respectively communicating with a liquid inlet and a filtrate outlet provided on the housing.
摘要翻译：通过用非离子，氨基酸或非离子的氟基表面活性剂覆盖多孔膜基底来获得亲水性多孔膜。对于覆盖物，将多孔膜基材浸渍在含有表面活性剂的溶液中，然后干燥膜基材。通过使多孔膜基材的表面和内孔表面具有极性基团，然后用亲水性聚合物膜覆盖膜基材，获得不同的亲水性多孔膜。对于该覆盖物，在将极性基团引入到多孔膜基材和内孔表面的表面之后，将膜基材浸渍在含有亲水性物质的溶液中，然后干燥。在使用任何这些亲水性多孔膜的液体过滤器中，多孔膜设置在壳体中，以将壳体内部空间分成两个分别与液体入口和设置在壳体上的滤液出口连通的子空间。

6. 发明授权

US06890373B2 Adsorbents, process for producing the same, and applications thereof 失效
标题翻译：吸附剂，其制备方法及其应用
公开(公告)号：US06890373B2
公开(公告)日：2005-05-10
申请号：US10296163
申请日：2001-06-13
申请人： Yasushi Nemoto , Hisashi Mori , Tadashi Kuwahara
发明人： Yasushi Nemoto , Hisashi Mori , Tadashi Kuwahara
IPC分类号： B01D53/04 , B01J20/20 , B01J20/32 , B01J47/00 , G11B33/14
CPC分类号： B01D53/02 , B01D2253/102 , B01D2253/104 , B01D2253/106 , B01D2253/108 , B01D2253/112 , B01D2253/202 , B01D2253/206 , B01D2253/304 , B01D2253/308 , B01D2257/80 , B01D2257/90 , B01D2259/4146 , B01D2259/4508 , B01J20/06 , B01J20/08 , B01J20/103 , B01J20/14 , B01J20/16 , B01J20/20 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/28004 , B01J20/28019 , B01J20/2805 , B01J20/28078 , B01J20/305 , B01J20/3204 , B01J20/3236 , B01J20/327 , B01J20/3272 , B01J20/3276 , B01J20/3289 , B01J20/3293 , B01J47/018 , B01J2220/49 , G11B33/1453 , G11B33/146 , Y10T428/2998
摘要： An adsorbent includes core particles containing an adsorbing material; a porous coating layer including a polymer material that coats the core particles; and an underlying layer containing a metal compound and disposed between the core particles and the porous coating layer. The porous coating layer is formed by spraying and applying a suspension or a solution containing the polymer material over the adsorbing material, or by immersing the adsorbing material into the suspension or the solution.
摘要翻译：吸附剂包括含有吸附材料的核心颗粒; 多孔涂层，其包括涂覆核心颗粒的聚合物材料; 以及包含金属化合物并且设置在芯颗粒和多孔涂层之间的下层。通过将吸附材料上的悬浮液或含有聚合物材料的溶液喷雾并涂布在悬浮液或溶液中而形成多孔涂层。

7. 发明申请

US20050107868A1 Scaffold for tissue engineering, artificial blood vessel, cuff, and biological implant covering member 审中-公开
公开(公告)号：US20050107868A1
公开(公告)日：2005-05-19
申请号：US10950620
申请日：2004-09-28
申请人： Yasuhide Nakayama , Eisuke Tatsumi , Yasushi Nemoto
发明人： Yasuhide Nakayama , Eisuke Tatsumi , Yasushi Nemoto
IPC分类号： A61L27/38 , A61L27/50 , A61L27/56 , A61F2/06 , A61F2/02
CPC分类号： A61L27/38 , A61L27/507 , A61L27/56
摘要： The invention provides a porous scaffold for tissue engineering which allows easy cell engraftment and cell culture and thus enables stable organization and an artificial blood vessel which exhibits high patency rate even if the inner diameter is small. The scaffold for tissue engineering is made of thermoplastic resin which forms a porous three-dimensional network structure having communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 650 μm and an apparent density of from 0.01 to 0.5 g/cm3. The artificial blood vessel is composed of this scaffold. The invention provides a cuff which allows easy infiltration of cells from living subcutaneous tissues, easy engraftment of cells, and neovascularization of capillary vessels so as to obtain robust bonding with subcutaneous tissues and, as a result, ensures separation of a wounded portion from the outside, thereby blocking exacerbation factors such as bacterial infection on healing and inhibiting progression of downgrowth. That is, the invention provides a cuff with none or little infection trouble such as tunnel infection. The cuff comprises a porous three-dimensional network structure which is made of thermoplastic resin or thermosetting resin and has communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 1000 μm and apparent density of from 0.01 to 0.5 g/cm3. The invention provides a biological implant covering member which allows easy infiltration of cells from living subcutaneous tissues, easy engraftment of cells, and organization, thereby obtaining robust bonding with native tissues and therefore protecting a living body from adverse effect which may occur due to the insertion of a biological implantation member into the living body. The biological implant covering member comprises a porous three-dimensional network structure which is made of thermoplastic resin or thermosetting resin and has communication property, wherein the porous three-dimensional network structure has an average pore diameter of from 100 to 1000 μm and apparent density of from 0.01 to 0.5 g/cm3.

8. 发明授权

US5203997A Hydrophilic porous membrane, method of manufacturing the same and liquid filter using the same 失效
标题翻译：亲水多孔膜，其制造方法和使用其的液体过滤器
公开(公告)号：US5203997A
公开(公告)日：1993-04-20
申请号：US345244
申请日：1989-05-01
申请人： Noriyuki Koyama , Shinsuke Yokomati , Yasushi Nemoto , Makoto Ohnishi
发明人： Noriyuki Koyama , Shinsuke Yokomati , Yasushi Nemoto , Makoto Ohnishi
IPC分类号： A61M1/34 , A61M1/22 , B01D67/00 , B01D71/34 , B01D71/52 , B01D71/82 , C08J9/40
CPC分类号： B01D67/0088 , B01D67/0093
摘要： A hydrophilic porous membrane is obtained by covering porous membrane substrate with a non-ionic, amino-acid-based or non-ionic fluorine-based surface active agent. For the covering, the porous membrane substrate is immersed in a solution containing the surface active agent and then drying the membrane substrate. A different hydrophilic porous membrane is obtained by providing the surfaces of a porous membrane substrate and inner pore surfaces with a polar group and then covering the membrane substrate with a hydrophilic polymer film. For this covering, after introduction of the polar group to the surfaces of the porous membrane substrate and inner pore surfaces, the membrane substrate is immersed in a solution containing a hydrophilic substance and then dried. In a liquid filter using any of these hydrophilic porous membrane, the porous membrane is disposed in a housing such as to divide the housing inner space into two sub-spaces respectively communicating with a liquid inlet and a filtrate outlet provided on the housing.

9. 发明授权

US5120440A Hydrophilic porous membrane and process for preparing the same 失效
标题翻译：疏水多孔膜及其制备方法
公开(公告)号：US5120440A
公开(公告)日：1992-06-09
申请号：US523027
申请日：1990-05-14
申请人： Yasushi Nemoto , Shinsuke Yokomachi , Hideaki Kito
发明人： Yasushi Nemoto , Shinsuke Yokomachi , Hideaki Kito
IPC分类号： A61M1/34 , A61M1/22 , B01D67/00 , B01D69/02 , B01D71/34 , B01D71/76 , C08J3/09 , C08J9/40
CPC分类号： B01D67/0088 , C08J3/09
摘要： There is disclosed a hydrophilic porous membrane in which a mixture composed of a surfactant, a hydrophilic polymer which is insoluble to water and alcohol, and a water soluble polymer is retained on the surface of a hydrophobic porous membrane material and/or at inner surface of pores and the surfactant is retained by the hydrophilic polymer.By taking the above constitution, a hydrophilic porous membrane which is restrained in dissolution and generation of foaming and is excellent in safety can be obtained.

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