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1. 外观设计

USD1040914S1 Stylus 有权
公开(公告)号：USD1040914S1
公开(公告)日：2024-09-03
申请号：US29891401
申请日：2023-05-05
申请人： Yan Yang
设计人： Yan Yang
摘要： FIG. 1 is a front, right and top perspective view of a stylus, showing my new design;
FIG. 2 is a rear, left and bottom perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is an enlarged top plan view thereof;
FIG. 8 is an enlarged bottom plan view thereof; and,
FIG. 9 is a front, right, and top perspective view of the stylus shown with the cap of the stylus detached.
The broken lines shown in the drawings illustrate portions of the stylus that form no part of the claimed design.

2. 发明授权

US09180775B2 Molding method of blow-molding hollow tank body with built-in component and pre-molding template device 有权
标题翻译：具有内置部件和预成型模板装置的吹塑中空罐体成型方法
公开(公告)号：US09180775B2
公开(公告)日：2015-11-10
申请号：US13389754
申请日：2009-10-26
申请人： Yan Sun , Lin Jiang , Liang Liu , Songjun Xu , Yihu Liu , Dejun Gao , Weidong Su , Dengqun Li , Yan Yang , Wenbin Hong , Ye Wang
发明人： Yan Sun , Lin Jiang , Liang Liu , Songjun Xu , Yihu Liu , Dejun Gao , Weidong Su , Dengqun Li , Yan Yang , Wenbin Hong , Ye Wang
IPC分类号： B29C43/02 , B60K15/03 , B29C51/26 , B29C51/30 , B29C51/10 , B29C51/12 , B29L31/00 , B29C47/00 , B29C51/38
CPC分类号： B60K15/03177 , B29C47/0023 , B29C47/0054 , B29C47/0066 , B29C51/10 , B29C51/12 , B29C51/261 , B29C51/262 , B29C51/267 , B29C51/30 , B29C51/38 , B29C2791/006 , B29C2791/007 , B29C2793/0063 , B29L2031/7172 , B60K2015/03032 , B60K2015/03453
摘要： A molding method of blow-molding a hollow tank body with a built-in component is provided. The method molds the hollow tank body by molding the sheet parisons in the half molds. After the moving cooperation of the half molds, an expanding mechanism of a pre-molding template device, the template half plates and the bases, the half molds are respectively leaned against the closed template half plates, and the sheet parisons are leaned against the half molds by blowing and/or sucking so as to be pre-molded. The tank body is molded after placing the component into it. A pre-molding template device is also provided. An expanding mechanism and the template half plates are mounted on the bases, and the bases are mounted on a rail bracket, the bases are driven by a power device to move on the rail bracket.
摘要翻译：提供了一种用内置部件吹塑中空箱体的成型方法。该方法通过在半模中模制板型坯来模制中空罐体。在半模的移动协作之后，预成型模板装置，模板半板和底座的扩展机构，半模分别靠在封闭的模板半板上，并且板型材靠在半通过吹塑和/或吸取模具以预成型。在将组件放入其中后，罐体被模制。还提供了预成型模板装置。扩展机构和模板半板安装在基座上，基座安装在导轨支架上，基座由动力装置驱动，在导轨支架上移动。

3. 发明授权

US08926998B2 Polycarbonates bearing pendant primary amines for medical applications 有权
标题翻译：聚碳酸酯承载用于医疗应用的仲胺
公开(公告)号：US08926998B2
公开(公告)日：2015-01-06
申请号：US13611116
申请日：2012-09-12
申请人： James L. Hedrick , Shrinivas Venkataraman , Yi Yan Yang
发明人： James L. Hedrick , Shrinivas Venkataraman , Yi Yan Yang
IPC分类号： A01N25/00 , A61K31/00 , A61L33/00 , B05D3/02
CPC分类号： A01N25/22 , A61K9/1075 , A61K9/1273 , A61K9/19 , A61K9/5146 , A61K31/196 , A61K31/785 , A61K45/06 , A61K47/34 , Y02A50/473 , A01N37/44 , A01N43/90 , A61K2300/00
摘要： An antimicrobial composition comprises an anionic drug and an amine polymer comprising a first repeat unit of formula (2): wherein a′ is an integer equal to 1 or 2, b′ is an integer equal to 1 or 2, and each R′ is an independent monovalent radical selected from the group consisting of hydrogen, methyl, ethyl, and combinations thereof. G′ is a divalent linking group selected from the group consisting of a single bond and groups comprising at least one carbon. X− is a negatively charged counterion. The drug and the amine polymer are bound by noncovalent interactions.
摘要翻译：抗微生物组合物包含阴离子药物和包含式（2）的第一重复单元的胺聚合物：其中a'为等于1或2的整数，b'为等于1或2的整数，并且每个R'为选自氢，甲基，乙基及其组合的独立的一价基团。 G'是选自单键和包含至少一个碳的基团的二价连接基团。 X-是带负电的抗衡离子。药物和胺聚合物通过非共价相互作用结合。

4. 发明授权

US08921426B2 Cationic bis-urea compounds as effective antimicrobial agents 有权
标题翻译：阳离子双脲化合物作为有效的抗菌剂
公开(公告)号：US08921426B2
公开(公告)日：2014-12-30
申请号：US13449643
申请日：2012-04-18
申请人： Daniel Joseph Coady , Amanda Catherine Engler , Kazuki Fukushima , James Lupton Hedrick , Shaoqiong Liu , Hareem Tariq Maune , Alshakim Nelson , Jed Walter Pitera , Yi Yan Yang
发明人： Daniel Joseph Coady , Amanda Catherine Engler , Kazuki Fukushima , James Lupton Hedrick , Shaoqiong Liu , Hareem Tariq Maune , Alshakim Nelson , Jed Walter Pitera , Yi Yan Yang
IPC分类号： A01N47/28 , A61K31/17 , C07C273/00 , C07C275/00
CPC分类号： A61K31/14 , A61K31/17 , B82Y5/00 , B82Y30/00 , C07C275/40 , C12N15/87
摘要： A cationic bis-urea compound is disclosed of formula (1): wherein: each m is independently an integer of 0 to 4, each k is independently 0 or 1, each Z′ is a monovalent radical independently selected from the group consisting of hydroxyl (*—OH), carboxyl (*—COOH), cyano (*—CN), nitro (*—NO2), sulfonate (*—SO3−), trifluoromethyl (*—CF3), halides, amine groups, ketone groups, alkyl groups comprising 1 to 6 carbons, alkoxy groups comprising 1 to 6 carbons, thioether groups comprising 1 to 6 carbons, and combinations thereof, each L′ is independently a divalent alkylene group comprising 1 to 6 carbons, wherein a *-[-L′-]k- is a single bond when k is 0, each Y′ is independently a monovalent non-polymeric radical comprising a positive charged amine, and each X′ is independently a negative charged counterion.
摘要翻译：公开了式（1）的阳离子双脲化合物：其中：每个m独立地为0至4的整数，每个k独立地为0或1，每个Z'是独立地选自羟基的一价基团（* -OH），羧基（* -COOH），氰基（* -CN），硝基（* -NO 2），磺酸酯（* -SO 3 - ），三氟甲基包含1至6个碳的烷基，包含1至6个碳原子的烷氧基，含1至6个碳的硫醚基及其组合，每个L'独立地为包含1至6个碳的二价亚烷基，其中a * - [ - L ' - ] k-当k为0时为单键，每个Y'独立地为包含带正电胺的单价非聚合基团，并且每个X'独立地为负电荷的抗衡离子。

5. 发明授权

US08703197B2 Branched polyamines for delivery of biologically active materials 失效
标题翻译：用于递送生物活性材料的分支多胺
公开(公告)号：US08703197B2
公开(公告)日：2014-04-22
申请号：US13613338
申请日：2012-09-13
申请人： Wei Cheng , Daniel J. Coady , Amanda C. Engler , James L. Hedrick , Pei Yun Teo , Chuan Yang , Yi Yan Yang
发明人： Wei Cheng , Daniel J. Coady , Amanda C. Engler , James L. Hedrick , Pei Yun Teo , Chuan Yang , Yi Yan Yang
IPC分类号： A61K47/30 , C07D321/00 , C07H21/00
CPC分类号： C12N15/85 , C08G73/028
摘要： A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): wherein (n′+q) is a number equal to about 45 to about 70, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L′ is a divalent radical comprising 3 to 30 carbons, and q/(n′+q)×100% equals about 9% to about 47%.
摘要翻译：支链多胺包括约45至约70个主要叔胺基团，约90至约140个骨架仲胺基团，正数n'大于0的主链终止伯胺基团，正数q大于0的骨架终止式（2）的氨基甲酸酯基团：其中（n'+ q）是等于约45至约70的数，式（2）的星形键与支链多胺的主链氮连接，L'是二价包含3至30个碳的基团，q /（n'+ q）×100％等于约9％至约47％。

6. 发明申请

US20140080215A1 BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS 失效
标题翻译：用于交付生物活性材料的分支聚氨酯
公开(公告)号：US20140080215A1
公开(公告)日：2014-03-20
申请号：US13613338
申请日：2012-09-13
申请人： Wei Cheng , Daniel J. Coady , Amanda C. Engler , James L. Hedrick , Pei Yun Teo , Chuan Yang , Yi Yan Yang
发明人： Wei Cheng , Daniel J. Coady , Amanda C. Engler , James L. Hedrick , Pei Yun Teo , Chuan Yang , Yi Yan Yang
IPC分类号： C08G73/02 , C12N15/85
CPC分类号： C12N15/85 , C08G73/028
摘要： A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): wherein (n′+q) is a number equal to about 45 to about 70, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L′ is a divalent radical comprising 3 to 30 carbons, and q/(n′+q)×100% equals about 9% to about 47%.
摘要翻译：支链多胺包括约45至约70个主要叔胺基团，约90至约140个骨架仲胺基团，正数n'大于0的主链终止伯胺基团，正数q大于0的骨架终止式（2）的氨基甲酸酯基团：其中（n'+ q）是等于约45至约70的数，式（2）的星形键与支链多胺的主链氮连接，L'是二价包含3至30个碳的基团，q /（n'+ q）×100％等于约9％至约47％。

7. 发明申请

US20140072607A1 POLYCARBONATES BEARING PENDANT PRIMARY AMINES FOR MEDICAL APPLICATIONS 有权
标题翻译：支撑用于医疗应用的主要原料的聚碳酸酯
公开(公告)号：US20140072607A1
公开(公告)日：2014-03-13
申请号：US13611116
申请日：2012-09-12
申请人： James L. Hedrick , Shrinivas Venkataraman , Yi Yan Yang
发明人： James L. Hedrick , Shrinivas Venkataraman , Yi Yan Yang
IPC分类号： C08G64/40 , A61K9/00 , A61K31/785 , B05D5/00 , A01P1/00 , A61P31/00 , C09D169/00 , A01N37/44 , A01N37/46
CPC分类号： A01N25/22 , A61K9/1075 , A61K9/1273 , A61K9/19 , A61K9/5146 , A61K31/196 , A61K31/785 , A61K45/06 , A61K47/34 , Y02A50/473 , A01N37/44 , A01N43/90 , A61K2300/00
摘要： An antimicrobial composition comprises an anionic drug and an amine polymer comprising a first repeat unit of formula (2): wherein a′ is an integer equal to 1 or 2, b′ is an integer equal to 1 or 2, and each R′ is an independent monovalent radical selected from the group consisting of hydrogen, methyl, ethyl, and combinations thereof. G′ is a divalent linking group selected from the group consisting of a single bond and groups comprising at least one carbon. X− is a negatively charged counterion. The drug and the amine polymer are bound by noncovalent interactions.
摘要翻译：抗微生物组合物包含阴离子药物和包含式（2）的第一重复单元的胺聚合物：其中a'为等于1或2的整数，b'为等于1或2的整数，并且每个R'为选自氢，甲基，乙基及其组合的独立的一价基团。 G'是选自单键和包含至少一个碳的基团的二价连接基团。 X-是带负电的抗衡离子。药物和胺聚合物通过非共价相互作用结合。

8. 发明授权

US08600109B2 Image object tracking using a particle filter 有权
标题翻译：使用粒子滤镜的图像对象跟踪
公开(公告)号：US08600109B2
公开(公告)日：2013-12-03
申请号：US13296654
申请日：2011-11-15
申请人： Chun-Fu Shen , Der-Chun Cherng , Sheng-Yan Yang , Yan-Chen Lu
发明人： Chun-Fu Shen , Der-Chun Cherng , Sheng-Yan Yang , Yan-Chen Lu
IPC分类号： G06K9/00
CPC分类号： G06T7/251 , G06T2200/28 , G06T2207/10024 , G06T2207/20021 , G06T2207/30212 , G06T2207/30232
摘要： A particle filter is suitable for performing particle filtering on a frame to track a particular object in the frame. The particle filter includes a frame cache, an observation model generator, and a particle filter controller. The frame cache is connected to a system memory through a system bus, in which the system memory stores all image blocks of the frame; and the frame cache obtains the at least one image block of the frame from the system memory and stores the obtained image block. The observation model generator reads at least one pixel from the frame cache, and generates an observation model corresponding to the object and the read image block according to the read pixel. The particle filter controller obtains the observation model from the observation model generator, and determines and outputs an object tracking result of the object according to the observation model.
摘要翻译：粒子滤波器适用于对帧执行粒子滤波以跟踪帧中的特定对象。粒子滤波器包括帧缓存，观察模型生成器和粒子滤波器控制器。帧缓存通过系统总线连接到系统存储器，其中系统存储器存储帧的所有图像块; 并且帧高速缓存从系统存储器获取帧的至少一个图像块并存储所获得的图像块。观察模型生成器从帧高速缓存读取至少一个像素，并且根据读取的像素生成与对象和读取图像块对应的观察模型。粒子滤波器控制器从观测模型发生器获取观测模型，根据观测模型确定并输出对象的物体跟踪结果。

9. 发明申请

US20130225481A1 ANTIMICROBIAL PEPTIDES 有权
标题翻译：抗菌肽
公开(公告)号：US20130225481A1
公开(公告)日：2013-08-29
申请号：US13882320
申请日：2011-10-31
申请人： Yi-Yan Yang , Nikken Wiradharma , Charlotte A.E. Hauser
发明人： Yi-Yan Yang , Nikken Wiradharma , Charlotte A.E. Hauser
IPC分类号： C07K7/08 , C07K7/06
CPC分类号： C07K7/08 , A61K38/00 , C07K7/06 , C07K14/00 , C07K14/4723
摘要： The present invention relates to antimicrobial peptides, to their use as antimicrobial agents and to their use in the treatment of (infectious) diseases, in particular infectious diseases caused by Gram-positive bacteria, Gram-negative bacteria, yeast or fungi. The present invention further relates to pharmaceutical compositions and kits comprising the antimicrobial peptides and to a method of lysing bacterial, yeast or fungal cells. The antimicrobial peptides consist of one of the following general formula: Wherein X is a hydrophobic amino acid, Y is a cationic amino acid, Z is an amino acid having a free thiol or thioether group, n is 2-4 and m is 0 or 1.
摘要翻译：本发明涉及抗微生物肽，其用作抗微生物剂，以及它们在治疗（感染性）疾病中的用途，特别是由革兰氏阳性菌，革兰氏阴性菌，酵母或真菌引起的感染性疾病。本发明还涉及包含抗微生物肽的药物组合物和试剂盒以及裂解细菌，酵母或真菌细胞的方法。抗微生物肽由以下通式之一组成：其中X为疏水性氨基酸，Y为阳离子型氨基酸，Z为具有游离巯基或硫醚基团的氨基酸，n为2-4，m为0或 1。

10. 发明授权

US08425900B2 Method of delivering a protein into a cell 失效
标题翻译：将蛋白质递送到细胞中的方法
公开(公告)号：US08425900B2
公开(公告)日：2013-04-23
申请号：US12598408
申请日：2008-04-30
申请人： Yi-Yan Yang , Yong Wang , Ashlynn Lingzhi Lee
发明人： Yi-Yan Yang , Yong Wang , Ashlynn Lingzhi Lee
IPC分类号： A61K38/43 , C12N9/00 , C12N9/16 , C12N5/00
CPC分类号： A61K9/1075 , A61K38/00 , A61K47/6907
摘要： There is presently provided a complex of a micelle formed from a cationic polymer and a protein, and a method using the complex to deliver the protein into a cell.
摘要翻译：目前提供了由阳离子聚合物和蛋白质形成的胶束的复合物，以及使用该复合物将蛋白质递送到细胞中的方法。

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