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1. 发明授权

US08297278B2 Dry powder inhaler 失效
标题翻译：干粉吸入器
公开(公告)号：US08297278B2
公开(公告)日：2012-10-30
申请号：US12892528
申请日：2010-09-28
申请人： Quentin Harmer , Roger William Clarke , Stephen William Eason
发明人： Quentin Harmer , Roger William Clarke , Stephen William Eason
IPC分类号： A61M11/00
CPC分类号： A61M15/0028 , A61M11/001 , A61M15/003 , A61M15/0036 , A61M15/0045 , A61M15/0048 , A61M2202/064 , A61M2206/16
摘要： An Inhaler for delivering an aerosolised dose of a powdered drug for inhalation by a user is disclosed. The inhaler comprises a drug entreinment device to a receive a package having a piercable lid containing a dose to be delivered, the device including a drug outlet tube terminating with a primary piercing element to pierce an opening in said lid when a package is located in the inhaler, a secondary piercing member to pierce a plurality of peripheral openings in said lid and, an airflow path to enable the supply of a charge of gas into the package via said peripheral openings to scour the interior of a pierced package such that all or substantially all of the dose is entrained in the gas and flows out of the package via the drug outlet tube. A medicament pack is also disclosed.
摘要翻译：公开了一种用于递送雾化剂量的粉末药物以吸引用户的吸入器。吸入器包括药物开启装置，以接收具有包含待递送剂量的可穿透盖的包装，该装置包括药物出口管，该药物出口管终止于主要刺穿元件，以在包装位于所述包装中时将所述盖中的开口刺穿吸入器，用于刺穿所述盖子中的多个周边开口的第二刺穿构件，以及气流路径，以便能够经由所述周边开口向包装中供应气体，以冲刷穿孔包装的内部，使得全部或基本上所有的剂量被夹带在气体中并通过药物出口管流出包装。还公开了一种药物包装。

2. 发明授权

US08245981B2 Ice shed reduction for leading edge structures 有权
标题翻译：前缘结构的减少冰川
公开(公告)号：US08245981B2
公开(公告)日：2012-08-21
申请号：US12112733
申请日：2008-04-30
申请人： Edward Atwood Rainous , Barry Lynn Allmon , Jeffre Gerry Loewe , William Clarke Brooks , Lee Alan Blanton , Courtney James Tudor , Vicky Showalter Budinger
发明人： Edward Atwood Rainous , Barry Lynn Allmon , Jeffre Gerry Loewe , William Clarke Brooks , Lee Alan Blanton , Courtney James Tudor , Vicky Showalter Budinger
IPC分类号： B64C21/00 , B64C1/38
CPC分类号： B64D15/00 , B64D33/02 , B64D2033/0233 , B64D2033/0286 , F01D9/04 , F01D25/02 , F01D25/162 , F02C7/047 , F05D2300/50212
摘要： A leading edge structure for use in an aerospace vehicle includes a body having a flowpath surface which defines a leading edge adapted to face an air flow during operation, and an opposed inner surface. The body is segmented into a plurality of portions having varying thermal properties and/or mechanical discontinuities, so as to promote stress concentrations in ice attached to the flowpath surface.
摘要翻译：用于航空航天车辆的前缘结构包括具有流动路径表面的主体，其限定了在操作期间适于面对空气流的前缘以及相对的内表面。主体被分割成具有变化的热性能和/或机械不连续性的多个部分，以促进附着在流路表面上的冰中的应力集中。

3. 外观设计

USD661795S1 Inhaler having cover 有权
标题翻译：吸入器有盖
公开(公告)号：USD661795S1
公开(公告)日：2012-06-12
申请号：US29359333
申请日：2010-04-08
申请人： Roger William Clarke , Matthew Neil Sarkar , Ivan Milivojevic
设计人： Roger William Clarke , Matthew Neil Sarkar , Ivan Milivojevic

4. 外观设计

USD646965S1 Dispenser 有权
公开(公告)号：USD646965S1
公开(公告)日：2011-10-18
申请号：US29347905
申请日：2010-07-22
申请人： Stephen William Eason , Roger William Clarke
设计人： Stephen William Eason , Roger William Clarke

5. 发明授权

US08038894B2 Method of selectively stripping an engine-run ceramic coating 有权
标题翻译：选择性剥离发动机运行的陶瓷涂层的方法
公开(公告)号：US08038894B2
公开(公告)日：2011-10-18
申请号：US11564639
申请日：2006-11-29
申请人： William Clarke Brooks
发明人： William Clarke Brooks
IPC分类号： B44C1/22
CPC分类号： C23G1/085 , B24C1/086 , C04B35/486 , C04B35/6306 , C04B2235/3241 , C04B2235/40 , C23F1/16
摘要： A process for selectively stripping a coating from a component of a turbomachine, and particularly a coating having a ceramic matrix that contains metallic particles dispersed therein that render the coating more difficult to remove from the component after the component has been subjected to elevated temperatures during operation of the turbomachine. The process generally includes immersing the component in an aqueous solution containing ferric chloride, nitric acid, and phosphoric acid, for a duration sufficient to attack the metallic particles in the coating. The component is then removed from the aqueous solution and its surface rinsed of the aqueous solution. The immersing and removing steps are then sequentially repeated a sufficient number of times to sufficiently attack the metallic particles to enable the coating to be mechanically removed from the component.
摘要翻译：一种用于从涡轮机组件选择性地剥离涂层的方法，特别是具有包含分散在其中的金属颗粒的陶瓷基体的涂层，其使得在组件在操作期间经受高温之后更难以从组件移除的涡轮机。该方法通常包括将组分浸入含有氯化铁，硝酸和磷酸的水溶液中持续足够时间以侵蚀涂层中的金属颗粒。然后从水溶液中除去组分，并将其表面漂洗水溶液。然后将浸渍和去除步骤顺序地重复足够的次数以充分攻击金属颗粒，以使涂层能够从组件机械地移除。

6. 外观设计

USD643529S1 Inhaler having cover 有权
公开(公告)号：USD643529S1
公开(公告)日：2011-08-16
申请号：US29359332
申请日：2010-04-08
申请人： Roger William Clarke , Matthew Paul Wright , Mike Paul Sheldon , Oliver Taylor Harvey
设计人： Roger William Clarke , Matthew Paul Wright , Mike Paul Sheldon , Oliver Taylor Harvey

7. 发明授权

US07992823B2 Ice shed reduction for leading edge structures 有权
标题翻译：前缘结构的减少冰川
公开(公告)号：US07992823B2
公开(公告)日：2011-08-09
申请号：US12112660
申请日：2008-04-30
申请人： Edward Atwood Rainous , Barry Lynn Allmon , Jeffre Gerry Loewe , William Clarke Brooks , Lee Alan Blanton , Courtney James Tudor , Vicky Showalter Budinger
发明人： Edward Atwood Rainous , Barry Lynn Allmon , Jeffre Gerry Loewe , William Clarke Brooks , Lee Alan Blanton , Courtney James Tudor , Vicky Showalter Budinger
IPC分类号： B64D15/00
CPC分类号： B64D15/00
摘要： A leading edge structure for use in an aerospace vehicle includes a body having a flowpath surface which defines a leading edge adapted to face an air flow during operation; and a metallic icephobic plating comprising nickel applied to at least a portion of the flowpath surface.
摘要翻译：用于航空航天车辆的前缘结构包括具有流动路径表面的主体，其限定在操作期间适于面对空气流的前缘; 以及包含施加到所述流路表面的至少一部分的镍的金属冰敷电镀。

8. 发明授权

US07845349B2 Inhaler 有权
标题翻译：吸入器
公开(公告)号：US07845349B2
公开(公告)日：2010-12-07
申请号：US10594730
申请日：2005-03-30
申请人： Stephen William Eason , Michael Edgar Newton , Roger William Clarke , Matthew Neil Sarkar
发明人： Stephen William Eason , Michael Edgar Newton , Roger William Clarke , Matthew Neil Sarkar
IPC分类号： A61M16/00
CPC分类号： A61M15/0028 , A61M15/0025 , A61M15/0026 , A61M15/0033 , A61M15/0091 , A61M15/0093 , A61M15/0096 , A61M16/107 , A61M16/207 , A61M16/208 , A61M2202/064 , A61M2205/073 , A61M2205/581 , A61M2205/583
摘要： An inhaler (1) for the delivery of a dose of powdered medicament for inhalation by a user comprising a housing (2) containing a cylinder (5) defining a chamber (5a) and a piston (6) movably received in the cylinder to enable a user to generate a charge of compressed air in the chamber to entrain a dose when the charge is released, wherein the cylinder and the piston include co-operating means (8, 9) thereon operable to draw the piston into the cylinder to compress a charge of air in the chamber in response to rotation of the piston.
摘要翻译：一种吸入器（1），用于输送用于用户吸入的一定剂量的粉末药物，其包括容纳限定腔室（5a）的气缸（5）和可移动地容纳在气缸中的活塞（6）的壳体（2），以使得能够用户在所述室中产生压缩空气的装料以在所述电荷被释放时夹带剂量，其中所述气缸和所述活塞包括其上可操作以将所述活塞拉入所述气缸中的合作装置（8,9），以压缩响应于活塞的旋转而对室内的空气进行充电。

9. 发明授权

US07810494B2 Dry powder inhaler 有权
标题翻译：干粉吸入器
公开(公告)号：US07810494B2
公开(公告)日：2010-10-12
申请号：US10571725
申请日：2004-09-15
申请人： Quentin Harmer , Roger William Clarke , Stephen William Eason
发明人： Quentin Harmer , Roger William Clarke , Stephen William Eason
IPC分类号： A61M11/00
CPC分类号： A61M15/0028 , A61M11/001 , A61M15/003 , A61M15/0036 , A61M15/0045 , A61M15/0048 , A61M2202/064 , A61M2206/16
摘要： An Inhaler for delivering an aerosolized dose of a powdered drug for inhalation by a user is disclosed. The inhaler comprises a drug entrainment device vice to a receive a package having a piercable lid containing a dose to be delivered, the device including a drug outlet tube terminating with a primary piercing element to pierce an opening in said lid when a package is located in the inhaler, a secondary piercing member to pierce a plurality of peripheral openings in said lid and, an airflow path to enable the supply of a charge of gas into the package via said peripheral openings to scour the interior of a pierced package such that all or substantially all of the dose is entrained in the gas and flows out of the package via the drug outlet tube. A medicament pack is also disclosed.
摘要翻译：公开了一种用于递送雾化剂量的粉末药物以吸引用户的吸入器。吸入器包括药物夹带装置，用于接收具有包含待输送剂量的可穿透盖的包装，该装置包括药物出口管，该药物出口管终止于主要刺穿元件，以在包装位于所述盖中时刺穿所述盖中的开口吸入器，用于刺穿所述盖中的多个周边开口的第二刺穿构件，以及用于经由所述周边开口供应气体进入包装的气流路径，以冲刷穿孔包装的内部，使得全部或基本上所有的剂量被夹带在气体中并通过药物出口管流出包装。还公开了一种药物包装。

10. 发明申请

US20100193538A1 DISPENSING DEVICE 审中-公开
标题翻译：分配设备
公开(公告)号：US20100193538A1
公开(公告)日：2010-08-05
申请号：US12665541
申请日：2008-06-18
申请人： Stephen William Clarke
发明人： Stephen William Clarke
IPC分类号： B65D83/00
CPC分类号： A47F1/04
摘要： A dispensing device comprises a loading chamber (12), a dispensing chamber (14), located beneath the loading chamber, a gate or shutter (24) movable between a first open position and a second closed position to allow selective communication of the loading chamber and the dispensing chamber. The device further comprises a first indicating means in the form of a first indicator member (114) which is retainable in a first-retracted position when the gate or shutter (24) is in the closed position and which is displaceable to a second, extended position when the gate or shutter is moved from the closed position to the open position. The device further comprises second indicating means (116) which is actuable to display a second visible signal to indicate that the first signal has been observed.
摘要翻译：分配装置包括装载室（12），位于装载室下方的分配室（14），可在第一打开位置和第二关闭位置之间移动的门或快门（24），以允许装载室和分配室。该装置还包括第一指示器构件（114）形式的第一指示装置，当第一指示器构件（114）处于关闭位置时，第一指示构件可保持在第一缩回位置，并且可移位到第二伸出位置当门或快门从关闭位置移动到打开位置时的位置。该装置还包括第二指示装置（116），其可致动以显示第二可见信号以指示已经观察到第一信号。

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