专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20110219788A1 CRYOGENIC STORAGE DEVICE 有权
标题翻译：低温储存装置
公开(公告)号：US20110219788A1
公开(公告)日：2011-09-15
申请号：US13129870
申请日：2009-11-09
申请人： Heiko Zimmermann , Uwe Schoen , Guenter R. Fuhr , Dirk Leuthold , Marianne Belke
发明人： Heiko Zimmermann , Uwe Schoen , Guenter R. Fuhr , Dirk Leuthold , Marianne Belke
IPC分类号： F25D13/06 , F25B49/00
CPC分类号： A01N1/0252 , F25B2700/04 , F25D3/102 , F25D3/11 , F25D29/001 , F25D2600/02 , F25D2700/12 , F25D2700/16 , G01N1/42 , G01N2035/00435
摘要： The invention relates to a cryogenic storage device and to a method for operating a cryogenic storage device, particularly for cryogenic storage of biological samples, comprising a sample carrying device that is set up to accommodate samples, a cryogenic container that is set up to accommodate the sample carrying device, a container cooling device with which the cryogenic container can be cooled, an intermediate storage container that is set up for intermediate storage of the sample carrying device, a transport device with which the sample carrying device can be moved between the cryogenic container and the intermediate storage container and a sensor device with which at least one operating parameter of the cryogenic storage device can be registered. The transport device is set up to be activated in dependence on an output signal from the sensor device upon registering a predetermined operating condition of the cryogenic storage device, so that the sample carrying device is moved from the cryogenic container to the intermediate storage container. Additionally or alternatively, an intermediate storage cooling device that is set up for cooling the intermediate storage container can be activated in dependence on an output signal of the sensor device.
摘要翻译：本发明涉及一种低温存储装置和一种用于操作低温存储装置的方法，特别是用于生物样品的低温储存的方法，包括设置用于容纳样品的样品携带装置，设置为容纳样品运送装置，用于冷冻低温容器的容器冷却装置，设置用于样品运送装置的中间储存的中间储存容器，运送装置，使样品运送装置能够在低温容器以及可以登记低温储存装置的至少一个操作参数的中间储存容器和传感器装置。传送装置被设置为在登记低温存储装置的预定操作条件时依赖于来自传感器装置的输出信号被激活，使得样品携带装置从低温容器移动到中间储存容器。另外或替代地，可以根据传感器装置的输出信号激活设置用于冷却中间存储容器的中间存储冷却装置。

2. 发明授权

US06407106B1 N-triazolylmethyl-piperazine compounds with neurokinin-receptor antagonist activity 有权
标题翻译： N-三唑基甲基 - 哌嗪化合物与神经激肽受体拮抗剂活性
公开(公告)号：US06407106B1
公开(公告)日：2002-06-18
申请号：US09915558
申请日：2001-07-27
申请人： Daniel Jasserand , Uwe Schoen , Holger Sann , Reinhard Brueckner , Christian Eeckhout
发明人： Daniel Jasserand , Uwe Schoen , Holger Sann , Reinhard Brueckner , Christian Eeckhout
IPC分类号： A61K315377
CPC分类号： C07D403/06 , C07D403/14
摘要： N-triazolylmethyl-piperazine compounds which exhibit neurokinin receptor antagonistic activity corresponding to the formula I: wherein R1, R2 and R3 have the meanings given in the specification; pharmaceutical compositions containing these compounds; a process for preparing these compounds, and intermediate products of this process.
摘要翻译：表现出对应于式I的神经激肽受体拮抗活性的N-三唑基甲基 - 哌嗪化合物：其中R1，R2和R3具有说明书中给出的含义; 含有这些化合物的药物组合物; 制备这些化合物的方法，以及该方法的中间产物。

3. 发明授权

US06291698B1 Process for preparing vinyl chlorosilanes 有权
标题翻译：制备乙烯基氯硅烷的方法
公开(公告)号：US06291698B1
公开(公告)日：2001-09-18
申请号：US09556403
申请日：2000-04-24
申请人： Stefan Bade , Bernt Kesper , Robert Koell , Hartwig Rauleder , Uwe Schoen
发明人： Stefan Bade , Bernt Kesper , Robert Koell , Hartwig Rauleder , Uwe Schoen
IPC分类号： C07F708
CPC分类号： C07F7/122
摘要： The invention relates to a process for preparing vinyl chlorosilanes, that includes thermally and non-catalytically reacting chlorosilane with vinyl chloride at a temperature of 550 to 700° C. by flowing the chlorosilane and vinyl chloride through a ring-gap space in a ring-gap reactor to produce a reaction gas; the ring-gap space having a cross-sectional area and a volume; and, after the flowing, further reacting, adiabatically, the reaction gas in a second zone to produce a hot reaction gas that contains vinylchiorosilane; wherein the second zone has a cross-sectional area that is greater than the cross-sectional area of the ring-gap space; and wherein the second zone has a volume that is in a ratio to the volume of the ring-gap space of 0.15:1 to 1.5:1. The invention also provides an apparatus for carrying out the above process.
摘要翻译：本发明涉及一种制备乙烯基氯硅烷的方法，其包括在550-700℃的温度下使氯代硅烷与氯乙烯进行热和非催化反应，通过使氯代硅烷和氯乙烯通过环 - 间隙反应器产生反应气体; 所述环间隙具有横截面积和体积; 并且在流动之后，绝热地将第二区中的反应气体进行反应，以产生含有乙烯基氯硅烷的热反应气体; 其中所述第二区域具有大于所述环形间隙的横截面面积的横截面面积; 并且其中所述第二区域具有与所述环隙空间的体积的比率为0.15:1至1.5:1的体积。本发明还提供一种用于执行上述过程的装置。

4. 发明授权

US5843948A Piperazinophenyl- and piperazinophenyloxycarboxylic acid derivatives, and processes and intermediates for their preparation and pharmaceutical compositions comprising them 失效
标题翻译：哌嗪基苯基和哌嗪苯氧基羧酸衍生物，以及其制备方法和中间体以及包含它们的药物组合物
公开(公告)号：US5843948A
公开(公告)日：1998-12-01
申请号：US994754
申请日：1997-12-19
申请人： Wolfgang Kehrbach , Uwe Schoen , Jack A. J. den Hartog , Jan H. van Maarseveen , Chris G. Kruse , Jochen Antel , Jan-Hendrik Reinders , Dieter Ziegler , Gerhard-Wilhelm Bielenberg
发明人： Wolfgang Kehrbach , Uwe Schoen , Jack A. J. den Hartog , Jan H. van Maarseveen , Chris G. Kruse , Jochen Antel , Jan-Hendrik Reinders , Dieter Ziegler , Gerhard-Wilhelm Bielenberg
IPC分类号： C07D295/08 , A61K31/495 , A61P7/02 , C07D213/74 , C07D213/78 , C07D295/14 , C07D295/155 , C07D295/135 , C07D401/04
CPC分类号： C07D213/74 , C07D295/155 , Y02P20/55
摘要： Compounds having fibrinogen receptor-antagonistic activity, of the general formula I ##STR1## in which Z is oxygen or a methylene group, B is a phenyl or pyridyl radical, R.sup.1 is hydrogen or a group forming a biolabile ester, and their physiologically acceptable acid addition salts and physiologically acceptable salts of acids of formula I.
摘要翻译：具有纤维蛋白原受体拮抗活性的化合物，其中Z为氧或亚甲基的通式I ，B为苯基或吡啶基，R 1为氢或形成不可生物酯的基团及其生理学上可接受的酸式I的酸的加成盐和生理上可接受的盐。

5. 发明授权

US09173887B2 Hepatitis C inhibitors and uses thereof 有权
标题翻译：丙型肝炎抑制剂及其用途
公开(公告)号：US09173887B2
公开(公告)日：2015-11-03
申请号：US13995701
申请日：2011-12-16
申请人： Clarence J. Maring , John K. Pratt , William A. Carroll , Dachun Liu , David A. Betebenner , Douglas K. Hutchinson , Michael D. Tufano , Todd W. Rockway , Uwe Schoen , Axel Pahl , Adreas Witte
发明人： Clarence J. Maring , John K. Pratt , William A. Carroll , Dachun Liu , David A. Betebenner , Douglas K. Hutchinson , Michael D. Tufano , Todd W. Rockway , Uwe Schoen , Axel Pahl , Adreas Witte
IPC分类号： C07D405/14 , C07D405/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , A61K31/5395 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/437 , C07F7/18 , A61K31/4245 , A61K31/513 , A61K31/5377 , A61K31/541 , A61K31/675 , A61K45/06 , C07F9/6558
CPC分类号： C07F7/1804 , A61K31/4178 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/437 , A61K31/506 , A61K31/513 , A61K31/5377 , A61K31/5395 , A61K31/541 , A61K31/675 , A61K31/695 , A61K45/06 , B65D88/703 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07F9/65586 , F16K31/363 , Y10T137/86405 , Y10T137/86421
摘要： This disclosure relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
摘要翻译：本公开涉及：（a）其特别是抑制HCV的化合物及其盐; （b）可用于制备这些化合物和盐的中间体; （c）包含这些化合物和盐的组合物; （d）制备这种中间体，化合物，盐和组合物的方法; （e）使用这些化合物，盐和组合物的方法; 和（f）包含这些化合物，盐和组合物的试剂盒。

6. 发明申请

US20080255075A1 SUBSTITUTED ESTRATRIENE DERIVATIVES AS 17BETA HSD INHIBITORS 有权
标题翻译：作为17BETA HSD抑制剂的取代的ESTRATRIENE衍生物
公开(公告)号：US20080255075A1
公开(公告)日：2008-10-16
申请号：US11947025
申请日：2007-11-29
申请人： Josef MESSINGER , Uwe Schoen , Heinrich-Hubert Thole , Bettina Husen , Pasi Koskimies , Mikko Unkila
发明人： Josef MESSINGER , Uwe Schoen , Heinrich-Hubert Thole , Bettina Husen , Pasi Koskimies , Mikko Unkila
IPC分类号： A61K31/58 , C07J43/00 , A61P35/00
CPC分类号： C07J43/00
摘要： Substituted estratriene compounds of formula (I) useful in therapy, especially in the treatment or inhibition of a steroid hormone dependent disorder requiring the inhibition of a 17β-hydroxysteroid dehydrogenase (17β-HSD) type 1, type 2 and/or type 3 enzyme, as well as their salts, pharmaceutical compositions containing such compounds and processes for preparing such compounds.
摘要翻译：可用于治疗，特别是治疗或抑制需要抑制17β-羟类固醇脱氢酶（17β-HSD）1型，2型和/或3型酶的类固醇激素依赖性病症的式（I）化合物的取代雌三烯化合物，以及它们的盐，含有这些化合物的药物组合物和制备这些化合物的方法。

7. 发明申请

US20050261292A1 Pharmaceutical composition containing N-sulfamoyl-N'-arylpiperazines for the treatment or inhibition of obesity and related conditions 审中-公开
标题翻译：含有N-氨磺酰基-N'-芳基哌嗪的药物组合物用于治疗或抑制肥胖症及相关病症
公开(公告)号：US20050261292A1
公开(公告)日：2005-11-24
申请号：US11130268
申请日：2005-05-17
申请人： Jochen Antel , Michael Firnges , Peter-Colin Gregory , Uwe Reinecker , Uwe Schoen , Harald Waldeck , Michael Wurl , Dania Reiche
发明人： Jochen Antel , Michael Firnges , Peter-Colin Gregory , Uwe Reinecker , Uwe Schoen , Harald Waldeck , Michael Wurl , Dania Reiche
IPC分类号： A61K31/496 , A61K31/497 , A61K31/501 , A61K31/519 , A61K31/53 , C07D213/74 , C07D295/26 , C07D43/02
CPC分类号： A61K31/496 , A61K31/497 , A61K31/501 , A61K31/519 , A61K31/53 , C07D213/74 , C07D295/26
摘要： The present invention relates to the use of known and novel N-sulfamoyl-N′-arylpiperazines corresponding to Formula I and their physiologically compatible acid addition salts for the treatment or inhibition of obesity and related conditions.
摘要翻译：本发明涉及对应于式I的已知和新型N-氨磺酰基-N'-芳基哌嗪及其生理相容的酸加成盐在治疗或抑制肥胖症及相关病症中的用途。

8. 发明授权

US06222056B1 Process for preparing vinylchlorosilanes 有权
标题翻译：制备乙烯基氯硅烷的方法
公开(公告)号：US06222056B1
公开(公告)日：2001-04-24
申请号：US09556404
申请日：2000-04-24
申请人： Stefan Bade , Hartwig Rauleder , Uwe Schoen , Franz-Michael Bollenrath
发明人： Stefan Bade , Hartwig Rauleder , Uwe Schoen , Franz-Michael Bollenrath
IPC分类号： C07F714
CPC分类号： C07F7/122
摘要： The invention relates to a process for preparing vinylchlorosilanes by thermal non-catalyzed reaction of chlorosilanes with vinyl chloride at from 550 to 700° C., using a ring-gap reactor which includes rapidly cooling the hot reaction gases after they have flowed through the ring-gap space, by quenching them with a liquid.
摘要翻译：本发明涉及一种通过氯代硅烷与氯乙烯在550-700℃下的热非催化反应制备乙烯基氯硅烷的方法，该方法包括一个环流反应器，该反应器包括在热反应气体流过环后快速冷却间隙，用液体淬火。

9. 发明授权

US5324732A Crystalline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and pharmaceutical compositions containing them 失效
标题翻译： 9,9-亚烷基-3,7-二氮杂双环壬烷化合物的结晶富马酸盐和含有它们的药物组合物
公开(公告)号：US5324732A
公开(公告)日：1994-06-28
申请号：US980177
申请日：1992-11-23
申请人： Uwe Schoen , Walter Heitmann , Uwe Maetzel
发明人： Uwe Schoen , Walter Heitmann , Uwe Maetzel
IPC分类号： A61K31/435 , A61K31/439 , A61K31/445 , A61K31/495 , A61K31/4995 , A61P7/10 , A61P9/00 , C07C57/15 , C07D471/08 , C07D471/10 , C07D451/14
CPC分类号： C07D471/10 , C07C57/15
摘要： 1.5 Fumaric acid salts of N,N'-di-lower alkyl-substituted 9,9-alkylene-3,7-diazabicyclo[3.3.1 ]nonanes and a process for obtaining them in stoichiometrically pure and virtually non-hygroscopic form.
摘要翻译： 1.5 N，N'-二低级烷基取代的9,9-亚烷基-3,7-二氮杂双环[3.3.1]壬烷的富马酸盐及其以化学计量纯度和实际上不吸湿形式获得的方法。

10. 发明授权

US4906640A 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds and medicaments containing said compounds 失效
标题翻译： 3-磺酰基-3,7-二氮杂双环[3,3,1]壬烷化合物和含有所述化合物的药物
公开(公告)号：US4906640A
公开(公告)日：1990-03-06
申请号：US214032
申请日：1988-06-30
申请人： Uwe Schoen , Wolfgang Kehrbach , Klaus-Ullrich Wolf
发明人： Uwe Schoen , Wolfgang Kehrbach , Klaus-Ullrich Wolf
IPC分类号： A61K31/435 , A61P1/14 , C07D471/08 , C07D471/10
CPC分类号： C07D471/08 , C07D471/10
摘要： 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds corresponding to the formula: ##STR1## wherein R.sup.1 is alkyl, cycloalkylalkyl or benzyl,R.sup.2 is hydrogen or lower alkyl,R.sup.3 is hydrogen or lower alkyl orR.sup.2 and R.sup.3 together form an alkylene chain, andR.sup.4 represents lower alkyl, thienyl, halogen substituted thienyl or a --(CH.sub.2).sub.n --R.sup.5 group, wherein n=0-3 andR.sup.5 is an optionally substituted phenyl group.The compounds are pharmacologically active, particularly in influencing the motility of the stomach.
摘要翻译：对应于式（I）的3-磺酰基-3,7-二氮杂双环[3,3,1]壬烷化合物，其中R 1是烷基，环烷基烷基或苄基，R 2是氢或低级烷基，R 3是氢或更低烷基或R 2和R 3一起形成亚烷基链，并且R 4表示低级烷基，噻吩基，卤素取代的噻吩基或 - （CH 2）n -R 5基团，其中n = 0-3，R 5是任选取代的苯基。这些化合物具有药理活性，特别是影响胃的运动性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式