专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20090215097A1 Novel Polymer and Method of Measuring Cholesterol Therewith 有权
标题翻译：新型聚合物及其测定胆固醇的方法
公开(公告)号：US20090215097A1
公开(公告)日：2009-08-27
申请号：US11988475
申请日：2006-03-14
申请人： Tomokazu Itai , Kiyoko Mori , Yo Yagura , Isao Koyama , Naoyuki Yamamoto
发明人： Tomokazu Itai , Kiyoko Mori , Yo Yagura , Isao Koyama , Naoyuki Yamamoto
IPC分类号： C12Q1/60 , C08G69/08 , C08G63/00 , C08G63/66 , G01N33/92
CPC分类号： G01N33/92 , C08F210/00 , C08F293/00 , C08F293/005 , G01N2800/044
摘要： It is an object of the present invention to provide the method for determining cholesterol in lipoprotein and reagent for determining cholesterol comprising the polymer, and the present invention relates to the reagent for determining cholesterol in lipoproteins such as high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) and the determination method using the polymer comprising the following units as constituents:(iv) a polyethylene glycol segment represented by the general formula [1]: —(CH2CH2O)k— [1] (wherein, k represents an integer of 10 to 250); (v) a monomer unit represented by the general formula [2]: (wherein R1 represents a hydrogen atom or C1-C3 alkyl group); and (vi) a monomer unit represented by the general formula [3]: [wherein, R2 represents a hydrogen atom or C1-C3 alkyl group, and R3 represents a group represented by the general formula [4]: —COOR4 [4] (wherein, R4 represents an alkyl group, a haloalkyl group or a bornyl group), an alkyl group, an alkoxy group, an aralkyl group or an alkylcarbamoyl group; particularly, in the direct measurement of cholesterols such as HDL, LDL and VLDL contained in the sample, the reagent for determining cholesterol in the presence of said polymer, and the method for determining the concentration of cholesterol in a specific lipoprotein using said reagent for determining cholesterol, and a novel polymer.
摘要翻译：本发明的目的是提供用于测定脂蛋白胆固醇的方法和用于测定包含聚合物的胆固醇的试剂，本发明涉及用于测定脂蛋白中胆固醇的试剂，例如高密度脂蛋白（HDL），低密度脂蛋白密度脂蛋白（LDL）和非常低密度脂蛋白（VLDL）的方法，使用包含以下单元的聚合物作为成分的测定方法：（iv）由通式[1]表示的聚乙二醇片段： - formulae description =“In-line Formulas”end =“lead”？> - （CH2CH2O）k- [1] <？in-line-formula description =“In-line formula”end =“tail”？>（其中，k表示10〜250的整数）; （v）由通式[2]表示的单体单元：（其中R 1表示氢原子或C 1 -C 3烷基）; 和（vi）由通式[3]表示的单体单元：[其中，R 2表示氢原子或C 1 -C 3烷基，R 3表示由通式[4]表示的基团： -formulae description =“In-line Formulas”end =“lead”？> - COOR4 [4] <？in-line-formula description =“In-line Formulas”end =“tail”？>（其中，R4表示烷基，卤代烷基或冰片基），烷基，烷氧基，芳烷基或烷基氨基甲酰基; 特别是直接测定样品中含有的HDL，LDL，VLDL等胆固醇的方法，在所述聚合物存在下测定胆固醇的试剂，以及使用上述试剂测定特定脂蛋白中的胆固醇浓度的方法胆固醇和新型聚合物。

2. 发明授权

US08158375B2 Polymer and method of measuring cholesterol therewith 有权
标题翻译：聚合物和测量胆固醇的方法
公开(公告)号：US08158375B2
公开(公告)日：2012-04-17
申请号：US11988475
申请日：2006-03-14
申请人： Tomokazu Itai , Kiyoko Mori , Yo Yagura , Isao Koyama , Naoyuki Yamamoto
发明人： Tomokazu Itai , Kiyoko Mori , Yo Yagura , Isao Koyama , Naoyuki Yamamoto
IPC分类号： C12Q1/60
CPC分类号： G01N33/92 , C08F210/00 , C08F293/00 , C08F293/005 , G01N2800/044
摘要： It is an object of the present invention to provide the method for determining cholesterol in lipoprotein and reagent for determining cholesterol comprising the polymer, and the present invention relates to the reagent for determining cholesterol in lipoproteins such as high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) and the determination method using the polymer comprising the following units as constituents:(iv) a polyethylene glycol segment represented by the general formula [1]: —(CH2CH2O)k— [1] (wherein, k represents an integer of 10 to 250); (v) a monomer unit represented by the general formula [2]: (wherein R1 represents a hydrogen atom or C1-C3 alkyl group); and (vi) a monomer unit represented by the general formula [3]: [wherein, R2 represents a hydrogen atom or C1-C3 alkyl group, and R3 represents a group represented by the general formula [4]: —COOR4 [4] (wherein, R4 represents an alkyl group, a haloalkyl group or a bornyl group), an alkyl group, an alkoxy group, an aralkyl group or an alkylcarbamoyl group; particularly, in the direct measurement of cholesterols such as HDL, LDL and VLDL contained in the sample, the reagent for determining cholesterol in the presence of said polymer, and the method for determining the concentration of cholesterol in a specific lipoprotein using said reagent for determining cholesterol, and a novel polymer.
摘要翻译：本发明的目的是提供用于测定脂蛋白胆固醇的方法和用于测定包含聚合物的胆固醇的试剂，本发明涉及用于测定脂蛋白中胆固醇的试剂，例如高密度脂蛋白（HDL），低密度脂蛋白密度脂蛋白（LDL）和非常低密度脂蛋白（VLDL）的测定方法以及使用包含以下单元的聚合物作为成分的测定方法：（iv）由通式[1]表示的聚乙二醇片段： - （CH 2 CH 2 O）k - [1]（其中，k表示10〜250的整数）。（v）由通式[2]表示的单体单元：（其中R 1表示氢原子或C 1 -C 3烷基）; 和（vi）由通式[3]表示的单体单元：[其中，R 2表示氢原子或C 1 -C 3烷基，R 3表示由通式[4]表示的基团：-COOR 4 [4] （其中，R4表示烷基，卤代烷基或冰基），烷基，烷氧基，芳烷基或烷基氨基甲酰基; 特别是直接测定样品中含有的HDL，LDL，VLDL等胆固醇的方法，在所述聚合物存在下测定胆固醇的试剂，以及使用上述试剂测定特定脂蛋白中的胆固醇浓度的方法胆固醇和新型聚合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式