会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明申请
    • Novel Polymer and Method of Measuring Cholesterol Therewith
    • 新型聚合物及其测定胆固醇的方法
    • US20090215097A1
    • 2009-08-27
    • US11988475
    • 2006-03-14
    • Tomokazu ItaiKiyoko MoriYo YaguraIsao KoyamaNaoyuki Yamamoto
    • Tomokazu ItaiKiyoko MoriYo YaguraIsao KoyamaNaoyuki Yamamoto
    • C12Q1/60C08G69/08C08G63/00C08G63/66G01N33/92
    • G01N33/92C08F210/00C08F293/00C08F293/005G01N2800/044
    • It is an object of the present invention to provide the method for determining cholesterol in lipoprotein and reagent for determining cholesterol comprising the polymer, and the present invention relates to the reagent for determining cholesterol in lipoproteins such as high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) and the determination method using the polymer comprising the following units as constituents:(iv) a polyethylene glycol segment represented by the general formula [1]: —(CH2CH2O)k—  [1] (wherein, k represents an integer of 10 to 250); (v) a monomer unit represented by the general formula [2]: (wherein R1 represents a hydrogen atom or C1-C3 alkyl group); and (vi) a monomer unit represented by the general formula [3]: [wherein, R2 represents a hydrogen atom or C1-C3 alkyl group, and R3 represents a group represented by the general formula [4]: —COOR4  [4] (wherein, R4 represents an alkyl group, a haloalkyl group or a bornyl group), an alkyl group, an alkoxy group, an aralkyl group or an alkylcarbamoyl group; particularly, in the direct measurement of cholesterols such as HDL, LDL and VLDL contained in the sample, the reagent for determining cholesterol in the presence of said polymer, and the method for determining the concentration of cholesterol in a specific lipoprotein using said reagent for determining cholesterol, and a novel polymer.
    • 本发明的目的是提供用于测定脂蛋白胆固醇的方法和用于测定包含聚合物的胆固醇的试剂,本发明涉及用于测定脂蛋白中胆固醇的试剂,例如高密度脂蛋白(HDL),低密度脂蛋白 密度脂蛋白(LDL)和非常低密度脂蛋白(VLDL)的方法,使用包含以下单元的聚合物作为成分的测定方法:(iv)由通式[1]表示的聚乙二醇片段: - formulae description =“In-line Formulas”end =“lead”?> - (CH2CH2O)k- [1] <?in-line-formula description =“In-line formula”end =“tail”?>(其中 ,k表示10〜250的整数); (v)由通式[2]表示的单体单元:(其中R 1表示氢原子或C 1 -C 3烷基); 和(vi)由通式[3]表示的单体单元:[其中,R 2表示氢原子或C 1 -C 3烷基,R 3表示由通式[4]表示的基团: -formulae description =“In-line Formulas”end =“lead”?> - COOR4 [4] <?in-line-formula description =“In-line Formulas”end =“tail”?>(其中,R4表示 烷基,卤代烷基或冰片基),烷基,烷氧基,芳烷基或烷基氨基甲酰基; 特别是直接测定样品中含有的HDL,LDL,VLDL等胆固醇的方法,在所述聚合物存在下测定胆固醇的试剂,以及使用上述试剂测定特定脂蛋白中的胆固醇浓度的方法 胆固醇和新型聚合物。
    • 2. 发明授权
    • Polymer and method of measuring cholesterol therewith
    • 聚合物和测量胆固醇的方法
    • US08158375B2
    • 2012-04-17
    • US11988475
    • 2006-03-14
    • Tomokazu ItaiKiyoko MoriYo YaguraIsao KoyamaNaoyuki Yamamoto
    • Tomokazu ItaiKiyoko MoriYo YaguraIsao KoyamaNaoyuki Yamamoto
    • C12Q1/60
    • G01N33/92C08F210/00C08F293/00C08F293/005G01N2800/044
    • It is an object of the present invention to provide the method for determining cholesterol in lipoprotein and reagent for determining cholesterol comprising the polymer, and the present invention relates to the reagent for determining cholesterol in lipoproteins such as high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) and the determination method using the polymer comprising the following units as constituents:(iv) a polyethylene glycol segment represented by the general formula [1]: —(CH2CH2O)k—  [1] (wherein, k represents an integer of 10 to 250); (v) a monomer unit represented by the general formula [2]: (wherein R1 represents a hydrogen atom or C1-C3 alkyl group); and (vi) a monomer unit represented by the general formula [3]: [wherein, R2 represents a hydrogen atom or C1-C3 alkyl group, and R3 represents a group represented by the general formula [4]: —COOR4  [4] (wherein, R4 represents an alkyl group, a haloalkyl group or a bornyl group), an alkyl group, an alkoxy group, an aralkyl group or an alkylcarbamoyl group; particularly, in the direct measurement of cholesterols such as HDL, LDL and VLDL contained in the sample, the reagent for determining cholesterol in the presence of said polymer, and the method for determining the concentration of cholesterol in a specific lipoprotein using said reagent for determining cholesterol, and a novel polymer.
    • 本发明的目的是提供用于测定脂蛋白胆固醇的方法和用于测定包含聚合物的胆固醇的试剂,本发明涉及用于测定脂蛋白中胆固醇的试剂,例如高密度脂蛋白(HDL),低密度脂蛋白 密度脂蛋白(LDL)和非常低密度脂蛋白(VLDL)的测定方法以及使用包含以下单元的聚合物作为成分的测定方法:(iv)由通式[1]表示的聚乙二醇片段: - (CH 2 CH 2 O)k - [1](其中,k表示10〜250的整数)。 (v)由通式[2]表示的单体单元:(其中R 1表示氢原子或C 1 -C 3烷基); 和(vi)由通式[3]表示的单体单元:[其中,R 2表示氢原子或C 1 -C 3烷基,R 3表示由通式[4]表示的基团:-COOR 4 [4] (其中,R4表示烷基,卤代烷基或冰基),烷基,烷氧基,芳烷基或烷基氨基甲酰基; 特别是直接测定样品中含有的HDL,LDL,VLDL等胆固醇的方法,在所述聚合物存在下测定胆固醇的试剂,以及使用上述试剂测定特定脂蛋白中的胆固醇浓度的方法 胆固醇和新型聚合物。