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1. 发明申请

US20080114397A1 Method for Closing an Opening in Tissue With a Splayable Staple 有权
标题翻译：用可折叠钉子封闭组织开口的方法
公开(公告)号：US20080114397A1
公开(公告)日：2008-05-15
申请号：US12013334
申请日：2008-01-11
申请人： Theodore Bender , Zachary Warder-Gabaldon , Matthew Newell , Bernard Hausen , Brian DuBois , Bryan Knodel
发明人： Theodore Bender , Zachary Warder-Gabaldon , Matthew Newell , Bernard Hausen , Brian DuBois , Bryan Knodel
IPC分类号： A61B17/064
CPC分类号： A61B17/0684 , A61B17/0057 , A61B17/0644 , A61B17/10 , A61B2017/00243 , A61B2017/00637 , A61B2017/00668
摘要： One method for closing an opening in tissue may include providing a substantially continuous solid staple having a plurality of tines and a longitudinal centerline, plastically deforming the staple to a splayed configuration; penetrating at least one tine into tissue in proximity to the opening; and plastically deforming the staple to a closed configuration. Another method for closing an opening in tissue may include providing a staple having a plurality of tines; plastically deforming the staple to a splayed configuration by applying force in the distal direction against a proximal surface of the staple; penetrating at least one tine into tissue in proximity to the opening; and plastically deforming the staple from the splayed configuration to a closed configuration by applying force in the distal direction against a proximal surface of the staple.
摘要翻译：用于关闭组织中的开口的一种方法可以包括提供具有多个尖齿和纵向中心线的基本上连续的实心短纤维，使订书钉塑形地变形成张开的构型; 将至少一个刺入到靠近开口的组织中; 并将钉子塑形变形成闭合构型。关闭组织中的开口的另一种方法可以包括提供具有多个齿的钉; 通过在远侧方向上施加相对于钉的近端表面的力，将钉子塑性变形成张开的构型; 将至少一个刺入到靠近开口的组织中; 并且通过在远侧方向上施加相对于钉的近端表面的力，将钉从张开形状塑造变形为闭合构型。

2. 发明申请

US20070250092A1 Device and methods for treatment of obesity 审中-公开
标题翻译：用于治疗肥胖症的装置和方法
公开(公告)号：US20070250092A1
公开(公告)日：2007-10-25
申请号：US11821325
申请日：2007-06-22
申请人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
发明人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
IPC分类号： A61B17/08 , A61M29/00
CPC分类号： A61F5/0073 , A61B5/036 , A61B5/04884 , A61B5/416 , A61B5/42 , A61B17/00234 , A61B17/072 , A61B17/07207 , A61B17/07292 , A61B17/115 , A61B17/1285 , A61B17/3468 , A61B2017/00278 , A61B2017/00942 , A61B2017/12018 , A61B2017/3484 , A61F5/003 , A61F5/0033 , A61N1/05 , A61N1/36007
摘要： Methods, devices, tools and assemblies for treating a patient to effect weight loss. One method embodiment involves passing a device including an expandable member in a collapsed configuration and a buoyancy member through an opening in the skin of a patient and into the abdominal cavity of the patient, and anchoring at least a portion of the expandable member, relative to at least one structure in the abdominal cavity. Devices including at least one expandable member and at least one buoyancy member are provided.
摘要翻译：用于治疗患者减轻体重的方法，装置，工具和装置。一个方法实施例涉及将包括处于折叠构造的可膨胀构件和浮力构件的装置通过患者皮肤中的开口传递到患者的腹腔中，并且相对于患者的至少一部分锚固可扩张构件腹腔中至少有一个结构。提供包括至少一个可膨胀构件和至少一个浮力构件的装置。

3. 发明申请

US20070250091A1 Devices and methods for treatment of obesity 审中-公开
公开(公告)号：US20070250091A1
公开(公告)日：2007-10-25
申请号：US11821149
申请日：2007-06-22
申请人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
发明人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
IPC分类号： A61B17/08
CPC分类号： A61F5/0073 , A61B5/036 , A61B5/04884 , A61B5/416 , A61B5/42 , A61B17/00234 , A61B17/072 , A61B17/07207 , A61B17/07292 , A61B17/115 , A61B17/1285 , A61B17/3468 , A61B2017/00278 , A61B2017/00942 , A61B2017/12018 , A61B2017/3484 , A61F5/003 , A61F5/0033 , A61N1/05 , A61N1/36007
摘要： Methods, devices, tools and assemblies for treating a patient to effect weight loss. One method embodiment involves passing a device including an expandable member in a collapsed configuration and a buoyancy member through an opening in the skin of a patient and into the abdominal cavity of the patient, and anchoring at least a portion of the expandable member, relative to at least one structure in the abdominal cavity. Devices including at least one expandable member and at least one buoyancy member are provided.

4. 发明申请

US20050267498A1 Tissue everting device and method 审中-公开
标题翻译：组织切片装置及方法
公开(公告)号：US20050267498A1
公开(公告)日：2005-12-01
申请号：US11187108
申请日：2005-07-22
申请人： Michael Hendricksen , Theodore Bender , Brendan Donohoe , Jaime Vargas , Andrew Frazier , Stephen Yencho , Bernard Hausen
发明人： Michael Hendricksen , Theodore Bender , Brendan Donohoe , Jaime Vargas , Andrew Frazier , Stephen Yencho , Bernard Hausen
IPC分类号： A61B17/00 , A61B17/02 , A61B17/064 , A61B17/08 , A61B17/11 , A61B17/115 , A61B17/32 , A61B17/34 , A61F2/06
CPC分类号： A61F2/064 , A61B17/0218 , A61B17/0644 , A61B17/11 , A61B17/115 , A61B17/1155 , A61B17/32053 , A61B17/3415 , A61B2017/0038 , A61B2017/0641 , A61B2017/1107 , A61B2017/1135 , A61B2017/3435 , A61F2/06 , A61F2/91 , A61F2/95 , A61F2002/8486 , A61F2002/9505 , A61F2002/9517
摘要： A device for everting an end of a hollow tissue structure may include a mandrel and a collar proximal to the mandrel. The mandrel may be elastomeric and deformable. At least one of the collar and the mandrel may be movable relative to the other. Deformation of the mandrel everts the end of the hollow tissue structure.
摘要翻译：用于覆盖中空组织结构的端部的装置可以包括心轴和靠近心轴的轴环。心轴可以是弹性体和可变形的。套环和心轴中的至少一个可以相对于另一个可移动。心轴的变形使得中空组织结构的端部脱离。

5. 发明申请

US20050038457A1 Tool for deploying an anastomosis device 审中-公开
标题翻译：用于部署吻合装置的工具
公开(公告)号：US20050038457A1
公开(公告)日：2005-02-17
申请号：US10934884
申请日：2004-09-03
申请人： Jaime Vargas , Stephen Yencho , James Nielsen , Brendan Donohoe , Theodore Bender , Brian DuBois , Scott Chamness , Nathan White , Gregory Arcenio , Heather Klaubert , Russell Mead
发明人： Jaime Vargas , Stephen Yencho , James Nielsen , Brendan Donohoe , Theodore Bender , Brian DuBois , Scott Chamness , Nathan White , Gregory Arcenio , Heather Klaubert , Russell Mead
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/11 , A61B17/115 , A61B17/12 , A61B17/32 , A61B17/34 , A61B17/92 , A61B17/08
CPC分类号： A61B17/32053 , A61B17/115 , A61B17/12013 , A61B2010/0208 , A61B2017/00252 , A61B2017/00969 , A61B2017/1103 , A61B2017/1107 , A61B2017/1135 , A61B2017/320064 , A61B2017/349 , A61B2017/925 , A61B2017/928
摘要： A tool for deploying an anastomosis device includes a member configured to hold the anastomosis device, and an expander movable relative to the anastomosis device.
摘要翻译：用于部署吻合装置的工具包括构造成保持吻合装置的构件，以及可相对于吻合装置移动的膨胀器。

6. 发明授权

US06471713B1 System for deploying an anastomosis device and method of performing anastomosis 有权
标题翻译：用于部署吻合装置的系统和执行吻合的方法
公开(公告)号：US06471713B1
公开(公告)日：2002-10-29
申请号：US09709373
申请日：2000-11-13
申请人： Jaime Vargas , Stephen A. Yencho , Jamey Nielsen , Michael Hendricksen , Bernard A. Hausen , Russell C. Mead, Jr. , Heather Klaubert , Brendan M. Donohoe , Theodore Bender
发明人： Jaime Vargas , Stephen A. Yencho , Jamey Nielsen , Michael Hendricksen , Bernard A. Hausen , Russell C. Mead, Jr. , Heather Klaubert , Brendan M. Donohoe , Theodore Bender
IPC分类号： A61B1704
CPC分类号： A61B17/11 , A61B17/320016 , A61B2017/00371 , A61B2017/1107 , A61B2017/1135 , A61F2/064
摘要： A deployment system for forming an incision in a target vessel, for placement of an anastomosis device and for deployment of an anastomosis device having an inner flange formed by radial expansion of the device and an outer flange formed by axial compression of the device.
摘要翻译：用于在靶容器中形成切口的部署系统，用于放置吻合装置并用于部署具有通过装置的径向膨胀形成的内凸缘的吻合装置和通过装置的轴向压缩形成的外凸缘。

7. 发明授权

US06398797B2 Tissue bonding system and method for controlling a tissue site during anastomosis 有权
标题翻译：组织结合系统和吻合期间控制组织部位的方法
公开(公告)号：US06398797B2
公开(公告)日：2002-06-04
申请号：US09725232
申请日：2000-11-29
申请人： David Bombard , Theodore Bender , Tenny Chang , Jaime Vargas , Michael Hendricksen , Stephen A. Yencho , Jamey Nielsen , Bernard A. Hausen , Brendan Donohoe
发明人： David Bombard , Theodore Bender , Tenny Chang , Jaime Vargas , Michael Hendricksen , Stephen A. Yencho , Jamey Nielsen , Bernard A. Hausen , Brendan Donohoe
IPC分类号： A61B1704
CPC分类号： A61B17/0644 , A61B17/0469 , A61B17/0482 , A61B17/064 , A61B17/072 , A61B17/11 , A61B17/115 , A61B17/1152 , A61B17/122 , A61B2017/00243 , A61B2017/07214 , A61B2017/07278 , A61B2017/1107 , A61B2017/1135 , A61B2090/037 , A61F2/064
摘要： A method and system for performing anastomosis uses an anvil to control and support a tissue site during an anastomosis procedure involving tissue bonding techniques such as tissue welding and adhesive tissue bonding. The anvil is particularly useful for supporting a wall of a coronary artery during attachment of a graft vessel in a coronary artery bypass graft procedure. The anvil is inserted into a pressurized or unpressurized target vessel and is pulled against an inner wall of the target vessel causing tenting of the thin tissue of the vessel wall. A graft vessel is then advanced to the anastomosis site and an end of the graft vessel is positioned adjacent an exterior of the target vessel. When tissue welding is used, a graft vessel fixture is positioned over the tissue surfaces to be welded in order to clamp the graft and target vessel tissue together. The tissue contacting surfaces of the anvil and/or graft vessel fixture are provided with one or more energy applying surfaces. Energy in the form of RF power, laser energy or ultrasonic energy is then applied to the compressed graft and target vessel tissue to weld the vessels together. When adhesive bonding is used, the adhesive may be applied to mating surfaces of the graft and/or target vessels either before or after the vessels are brought into contact. After tissue bonding is complete, an incision is formed in the wall of the target vessel to allow blood flow between the target vessel and the graft vessel. The incision may be made with an electro-cautery cutting device.
摘要翻译：用于进行吻合的方法和系统在涉及组织粘合技术例如组织焊接和粘合剂组织粘合的吻合过程中使用砧来控制和支撑组织部位。砧座特别可用于在冠状动脉旁路移植手术中移植血管附着期间支撑冠状动脉壁。将砧座插入加压或非加压的靶容器中并且被拉到靶容器的内壁上，导致容器壁的薄组织的隆起。移植血管然后前进到吻合部位，移植血管的末端位于靶血管外部附近。当使用组织焊接时，将移植物容器夹具放置在待焊接的组织表面上方，以将移植物和靶血管组织夹在一起。砧座和/或移植物容器固定装置的组织接触表面设置有一个或多个能量施加表面。然后将RF功率，激光能量或超声波能量的能量施加到压缩的移植物和靶血管组织上以将血管焊接在一起。当使用粘合剂时，粘合剂可以在容器接触之前或之后施加到移植物和/或靶容器的配合表面。在组织粘合完成之后，在靶容器的壁中形成切口以允许目标血管和移植血管之间的血液流动。切口可以用电火花切割装置制成。

8. 发明申请

US20080027472A1 Anastomosis System with Anvil Entry Hole Sealer 有权
标题翻译：砧孔入口封口机吻合系统
公开(公告)号：US20080027472A1
公开(公告)日：2008-01-31
申请号：US11865893
申请日：2007-10-02
申请人： James Nielsen , Nathan White , Theodore Bender , Philipe Manoux , David Bombard , Brendan Donohoe , Bryan Knodel
发明人： James Nielsen , Nathan White , Theodore Bender , Philipe Manoux , David Bombard , Brendan Donohoe , Bryan Knodel
IPC分类号： A61B17/11
CPC分类号： A61B17/0057 , A61B17/00491 , A61B17/0206 , A61B17/06166 , A61B17/064 , A61B17/0644 , A61B17/0686 , A61B17/072 , A61B17/07207 , A61B17/08 , A61B17/10 , A61B17/115 , A61B17/1152 , A61B17/122 , A61B17/32 , A61B90/50 , A61B2017/00654 , A61B2017/00893 , A61B2017/0641 , A61B2017/0688 , A61B2017/07214 , A61B2017/1103 , A61B2017/1107 , A61B2017/1135 , A61B2017/1157 , A61B2017/320052 , A61B2090/08021
摘要： A system for connecting the end of a graft vessel to the side of a target vessel may include an anvil configured to enter the target vessel through an anvil entry hole in the wall of the target vessel; a holder movable relative to the anvil, where that holder may deploy at least one connector through the graft vessel and into the target vessel at a location spaced apart from the anvil entry hole; and at least one sealer that may be detachably connected to the anvil and/or said holder; where at least one sealer may be configured to substantially close the anvil entry hole in the target vessel. A method for performing anastomosis between a graft vessel and a target vessel may include inserting an anvil through the wall of the target vessel into the lumen of the target vessel from outside of the target vessel through an anvil entry hole; connecting an end of the graft vessel to the side of the target vessel with a plurality of connectors at a location spaced apart from the anvil entry hole; creating an opening in the side of the target vessel, where the opening is located within a perimeter defined by the connectors and spaced apart from the anvil entry hole; withdrawing the anvil through the anvil entry hole; and substantially sealing the anvil entry hole.
摘要翻译：用于将移植物容器的端部连接到靶容器侧的系统可以包括构造成通过目标容器的壁中的砧孔入口进入靶容器的砧座; 相对于砧座可移动的保持器，其中该保持器可以在与砧座入口孔间隔开的位置处将至少一个连接器展开穿过移植物容器并进入目标血管; 以及可以可拆卸地连接到所述砧和/或所述保持器的至少一个密封件; 其中至少一个密封件可以构造成基本上封闭靶容器中的砧孔入口。用于在移植物容器和目标血管之间进行吻合的方法可以包括通过砧座入口孔将目标血管壁从目标血管外部插入到目标血管的内腔中; 在与所述砧座入口孔间隔开的位置处，使多个连接器将所述移植脉管的端部连接到所述靶容器侧; 在目标容器的侧面形成开口，其中开口位于由连接器限定的周边中并与砧座入口孔间隔开; 通过砧座入口将砧座取出; 并且基本上密封砧进入孔。

9. 发明申请

US20070250088A1 Devices and methods for treatment of obesity 审中-公开
标题翻译：用于治疗肥胖的装置和方法
公开(公告)号：US20070250088A1
公开(公告)日：2007-10-25
申请号：US11820411
申请日：2007-06-18
申请人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
发明人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
IPC分类号： A61B17/08 , A61M29/00
CPC分类号： A61B17/072 , A61B17/00234 , A61B17/07207 , A61B17/07292 , A61B17/115 , A61B2017/00876 , A61F5/0003 , A61F5/003 , A61F5/0073
摘要： Methods, devices, tools, instruments and systems for treating a patient to induce weight loss. In one method embodiment, a device, including an expandable member in a collapsed configuration, is passed through an opening in the skin of the patient, and into the abdominal cavity of the patient. At least a portion of the expandable member is anchored relative to at least one structure in the abdominal cavity, without piercing the stomach. The expandable member is expanded to an expanded configuration in a space in the abdominal cavity to perform at least one of: prevention of expansion of the stomach of the patient into the space; and compression of a portion of the stomach.
摘要翻译：用于治疗患者以诱导体重减轻的方法，装置，工具，仪器和系统。在一个方法实施例中，包括处于折叠构造的可膨胀构件的装置通过患者皮肤中的开口并进入患者的腹腔。可膨胀构件的至少一部分相对于腹腔中的至少一种结构锚固，而不刺穿胃。可膨胀构件在腹腔中的空间中膨胀成扩张构造，以执行以下至少一个：防止患者的胃膨胀到空间中; 并压缩一部分胃。

10. 发明申请

US20070250087A1 Devices and methods for treatment of obesity 审中-公开
公开(公告)号：US20070250087A1
公开(公告)日：2007-10-25
申请号：US11820355
申请日：2007-06-18
申请人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
发明人： Joshua Makower , Theodore Bender , Brian Shiu , Pablo Acosta , Shuji Uemura , Josef Friedmann , Crystine Lee
IPC分类号： A61B17/08
CPC分类号： A61B17/072 , A61B17/00234 , A61B17/07207 , A61B17/07292 , A61B17/115 , A61B2017/00876 , A61F5/0003 , A61F5/003 , A61F5/0073
摘要： Methods, devices, tools, instruments and systems for treating a patient to induce weight loss. In one method embodiment, a device, including an expandable member in a collapsed configuration, is passed through an opening in the skin of the patient, and into the abdominal cavity of the patient. At least a portion of the expandable member is anchored relative to at least one structure in the abdominal cavity, without piercing the stomach. The expandable member is expanded to an expanded configuration in a space in the abdominal cavity to perform at least one of: prevention of expansion of the stomach of the patient into the space; and compression of a portion of the stomach.

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