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    • 2. 发明授权
    • Time-resolved diffusion tomographic 2D and 3D imaging in highly
scattering turbid media
    • 在高散射混浊介质中的时间分辨扩散断层扫描2D和3D成像
    • US6108576A
    • 2000-08-22
    • US797163
    • 1997-02-10
    • Robert R. AlfanoWei CaiSwapan K. Gayen
    • Robert R. AlfanoWei CaiSwapan K. Gayen
    • A61B5/00G01N21/47A61B6/00
    • A61B5/0073A61B5/7257G01N21/4795A61B5/0091
    • A method for imaging objects in highly scattering turbid media. According to one embodiment of the invention, the method involves using a plurality of intersecting source/detectors sets and time-resolving equipment to generate a plurality of time-resolved intensity curves for the diffusive component of light emergent from the medium. For each of the curves, the intensities at a plurality of times are then inputted into the following inverse reconstruction algorithm to form an image of the medium: wherein W is a matrix relating output at source and detector positions r.sub.s and r.sub.d, at time t, to position r, .LAMBDA. is a regularization matrix, chosen for convenience to be diagonal, but selected in a way related to the ratio of the noise, to fluctuations in the absorption (or diffusion) X.sub.j that we are trying to determine:.LAMBDA..sub.ij =.lambda..sub.j .delta..sub.ij with .lambda..sub.j = / Y is the data collected at the detectors, and X.sup.k is the kth iterate toward the desired absorption information. An algorithm, which combines a two dimensional (2D) matrix inversion with a one-dimensional (1D) Fourier transform inversion is used to obtain images of three dimensional hidden objects in turbid scattering media.
    • 一种用于在高散射混浊介质中成像物体的方法。 根据本发明的一个实施例,该方法包括使用多个相交的源/检测器组和时间分辨设备来产生用于从介质出射的光的漫射分量的多个时间分辨强度曲线。 对于每个曲线,多个时间的强度然后被输入到以下逆重建算法中以形成介质的图像:其中W是在时间t处将源的输出和检测器位置rs和rd相关联的矩阵, 为了定位r,LAMBDA是一个正则化矩阵,为方便起见选择为对角线,但以与噪声的比值与我们试图确定的吸收(或扩散)Xj的波动相关的方式进行选择: LAMBDA ij = lambda j delta ij,其中λj = / Y是在检测器处收集的数据,Xk是朝向期望的吸收信息的第k次迭代。 将二维(2D)矩阵求逆与一维(1D)傅里叶变换反演相结合的算法用于获取浑浊散射介质中三维隐藏物体的图像。
    • 3. 发明授权
    • Excited state polarization altering optical filter
    • 激发态极化改变光滤波器
    • US5721632A
    • 1998-02-24
    • US521195
    • 1995-08-30
    • Richard I. BillmersMartin F. SquicciariniSwapan K. Gayen
    • Richard I. BillmersMartin F. SquicciariniSwapan K. Gayen
    • G02F1/01G02F1/03
    • G02F1/0126
    • An excited state polarization altering optical filter includes a vapor cell having a population of electrons with a plurality of energy levels that receive light and transmit light according to the received light. A first pulsed dye laser applies a beam of light by way of a circular polarizer to provide a first beam of light having a first polarization to the vapor cell. The first beam of light causes transitions of the electrons from one energy level to another energy level. A second pulsed dye laser applies a second beam of light with a second, differing, linear polarization to the vapor cell. The vapor cell differentially transmits the first and second beams of light in accordance with the differing polarizations. A delay path is provided for delaying the second beam of light before the second beam of light is applied to the vapor cell. The delay path is tuned by adjusting the length. A third laser applies a beam of light to the first and second lasers. The third laser may be an Nd:YAG laser.
    • 激发态极化改变光学滤波器包括具有多个能量水平的电子群的蒸汽池,所述能级接收光并根据接收的光透射光。 第一脉冲染料激光器通过圆偏振器施加光束,以向蒸气室提供具有第一偏振的第一光束。 第一束光使电子从一个能量级转变到另一个能级。 第二脉冲染料激光器将具有第二,不同的线性极化的第二光束施加到蒸气室。 蒸汽池根据不同的极化差分地传输第一和第二光束。 提供延迟路径用于在将第二光束施加到蒸气室之前延迟第二光束。 通过调整长度来调整延迟路径。 第三激光器将光束施加到第一和第二激光器。 第三激光器可以是Nd:YAG激光器。