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1. 发明申请

US20080109574A1 Method and system for synchronizing audio processing modules 有权
标题翻译：用于同步音频处理模块的方法和系统
公开(公告)号：US20080109574A1
公开(公告)日：2008-05-08
申请号：US12005911
申请日：2007-12-27
申请人： Stephen Holmes
发明人： Stephen Holmes
IPC分类号： G06F13/42
CPC分类号： G11B20/10527 , G06F3/16 , G11B20/10037 , G11B2020/10546 , G11B2020/1062
摘要： Embodiments of the present invention provide an audio system having wholly independent audio processing modules. The audio system includes a plurality of audio processing modules, a clock manager, a sample rate converter and a buffer. The audio processing modules are communicatively coupled to the clock manager and the buffer. The sample rate converter is communicatively coupled to the clock manager and the buffer. The buffer provides for storing audio data generated and consumed by the audio processing modules. The clock manager provides for determining the clock source of each audio processing module. The clock manager also provides for configuring the audio processing modules and the sample rate converter as a function the clock source of each audio processing module. The sample rate converter provides for synchronizing a flow rate of audio data generated by a first audio processing module and a flow rate of audio data consumed by a second audio processing module, when the clock source of the first and second audio processing modules are different.
摘要翻译：本发明的实施例提供一种具有完全独立音频处理模块的音频系统。音频系统包括多个音频处理模块，时钟管理器，采样率转换器和缓冲器。音频处理模块通信地耦合到时钟管理器和缓冲器。采样率转换器通信地耦合到时钟管理器和缓冲器。缓冲器用于存储由音频处理模块生成和消耗的音频数据。时钟管理器提供用于确定每个音频处理模块的时钟源。时钟管理器还提供将音频处理模块和采样率转换器配置为每个音频处理模块的时钟源的功能。当第一和第二音频处理模块的时钟源不同时，采样率转换器提供使由第一音频处理模块产生的音频数据的流率和第二音频处理模块所消耗的音频数据的流率同步。

2. 发明申请

US20060134062A1 Polymeric boronic acid derivatives as lipase inhibitors 审中-公开
标题翻译：聚合硼酸衍生物作为脂肪酶抑制剂
公开(公告)号：US20060134062A1
公开(公告)日：2006-06-22
申请号：US10535639
申请日：2003-11-19
申请人： Chad Huval , Xinhua Li , Stephen Holmes-Farley , Pradeep Dhal
发明人： Chad Huval , Xinhua Li , Stephen Holmes-Farley , Pradeep Dhal
IPC分类号： A61K31/785
CPC分类号： C08F230/06 , A61K31/69 , A61K45/06 , C08F30/06 , C08F220/56 , C08F220/60 , C08F226/10 , C08F265/00 , C08F289/00 , C08F290/06 , C08F290/14 , C08F291/00 , C08F293/005 , C08F297/00 , C08F297/02 , C08F2438/02
摘要： Human obesity is a health problem affecting a significant proportion of the American population. Numerous methods of treating obesity have been developed, but all have serious drawbacks. The present invention discloses a novel class of polymers with either a sulfur atom or an electron withdrawing group between a polymer backbone and a pendant aryl boronic acid group. Polymers having such an electron withdrawing group have been found to be particularly effective in inhibiting lipase in vitro and in vivo. Methods of treating obesity and reducing absorption of fat are also disclosed.
摘要翻译：人类肥胖是影响美国人口相当大比例的健康问题。已经开发出许多治疗肥胖症的方法，但都具有严重的缺点。本发明公开了一种新型聚合物，其在聚合物主链和芳基硼酸基团之间具有硫原子或吸电子基团。已经发现具有这种吸电子基团的聚合物在体外和体内特别有效地抑制脂肪酶。还公开了治疗肥胖和减少脂肪吸收的方法。

3. 发明申请

US20050244409A1 Erythropoietin receptor antibodies 审中-公开
标题翻译：红细胞生成素受体抗体
公开(公告)号：US20050244409A1
公开(公告)日：2005-11-03
申请号：US11173071
申请日：2005-07-01
申请人： Connie Erickson-Miller , Stephen Holmes , Alexander Taylor , Peter Young
发明人： Connie Erickson-Miller , Stephen Holmes , Alexander Taylor , Peter Young
IPC分类号： C12N15/09 , A61K39/395 , A61K45/00 , A61P7/00 , A61P7/06 , A61P13/12 , C07K16/28 , C12N5/10 , C12N15/12 , C12N15/13 , C12N15/14 , C12P21/08 , C12N5/06
CPC分类号： C07K16/2863 , A61K2039/505 , C07K2317/24
摘要： Erythropoietin receptor agonist and antagonist antibodies and their use in enhancing erythropoiesis are disclosed.
摘要翻译：公开了红细胞生成素受体激动剂和拮抗剂抗体及其在增强红细胞生成中的用途。

4. 发明申请

US20050234571A1 Method and system for synchronizing audio processing modules 有权
标题翻译：用于同步音频处理模块的方法和系统
公开(公告)号：US20050234571A1
公开(公告)日：2005-10-20
申请号：US10824759
申请日：2004-04-14
申请人： Stephen Holmes
发明人： Stephen Holmes
IPC分类号： G06F3/16 , G11B20/10 , H03H17/06 , H04L7/02 , G06F17/00
CPC分类号： G11B20/10527 , G06F3/16 , G11B20/10037 , G11B2020/10546 , G11B2020/1062
摘要： Embodiments of the present invention provide an audio system having wholly independent audio processing modules. The audio system includes a plurality of audio processing modules, a clock manager, a sample rate converter and a buffer. The audio processing modules are communicatively coupled to the clock manager and the buffer. The sample rate converter is communicatively coupled to the clock manager and the buffer. The buffer provides for storing audio data generated and consumed by the audio processing modules. The clock manager provides for determining the clock source of each audio processing module. The clock manager also provides for configuring the audio processing modules and the sample rate converter as a function the clock source of each audio processing module. The sample rate converter provides for synchronizing a flow rate of audio data generated by a first audio processing module and a flow rate of audio data consumed by a second audio processing module, when the clock source of the first and second audio processing modules are different.
摘要翻译：本发明的实施例提供一种具有完全独立音频处理模块的音频系统。音频系统包括多个音频处理模块，时钟管理器，采样率转换器和缓冲器。音频处理模块通信地耦合到时钟管理器和缓冲器。采样率转换器通信地耦合到时钟管理器和缓冲器。缓冲器用于存储由音频处理模块生成和消耗的音频数据。时钟管理器提供用于确定每个音频处理模块的时钟源。时钟管理器还提供将音频处理模块和采样率转换器配置为每个音频处理模块的时钟源的功能。当第一和第二音频处理模块的时钟源不同时，采样率转换器提供使由第一音频处理模块产生的音频数据的流率和第二音频处理模块所消耗的音频数据的流率同步。

5. 发明授权

US5336238A Surgical instrument capable of disassembly 失效
标题翻译：手术器械能拆卸
公开(公告)号：US5336238A
公开(公告)日：1994-08-09
申请号：US93477
申请日：1993-07-19
申请人： J. Stephen Holmes , Timothy Lamartina
发明人： J. Stephen Holmes , Timothy Lamartina
IPC分类号： A61B17/28 , A61B18/14 , A61B19/00
CPC分类号： A61B17/29 , A61B17/28 , A61B18/1442 , A61B2017/292 , A61B2017/2929 , A61B2090/0813
摘要： A surgical instrument which easily disassembles for sterilization comprises an inner rod coaxially disposed in a hollow tube with a handle at one end of the rod and a working tip at the other end. The handle is detachably interconnected to the inner rod and the inner rod is detachably interconnected to the hollow tube by means of at least one locking pin.
摘要翻译：容易拆卸灭菌的手术器械包括同轴地设置在中空管中的内杆，杆的一端具有手柄，另一端具有工作尖端。手柄可拆卸地互连到内杆，并且内杆通过至少一个锁定销可拆卸地互连到中空管。

6. 发明申请

US20120255578A1 VEHICLE MOUNTED APPARATUS FOR HIGH-PRESSURE FLUID BLASTING 有权
标题翻译：用于高压液体喷砂的车辆安装设备
公开(公告)号：US20120255578A1
公开(公告)日：2012-10-11
申请号：US13518543
申请日：2010-12-23
申请人： Stephen Holmes Robinson
发明人： Stephen Holmes Robinson
IPC分类号： B08B3/04 , B05B1/28
CPC分类号： E01C23/12 , B08B3/024 , B08B5/04 , E01C23/08 , E01C23/128 , E01H1/103
摘要： A vehicle mounted apparatus for high-pressure fluid blasting to remove material from or otherwise treat a surface, the apparatus comprising: a high-pressure fluid supply connected to a nozzle assembly containing at least one nozzle, the nozzle assembly being supported for movement along a track mounted transversely on the vehicle; and a suction device for conveying airflow and removed material through a conduit from the nozzle assembly to a treatment zone within the vehicle, the treatment zone having a separation means for accumulating removed material, a means for conveying airflow from the separation means to the suction device, and a to means for conveying the removed material to a storage zone.
摘要翻译：一种用于高压流体喷砂从而从表面去除或以其他方式处理表面的车载装置，所述装置包括：连接到包含至少一个喷嘴的喷嘴组件的高压流体供应装置，所述喷嘴组件被支撑以沿着轨道横向安装在车辆上; 以及用于将气流和去除的材料通过导管从喷嘴组件输送到车辆内的处理区的抽吸装置，处理区具有用于积聚去除的材料的分离装置，用于将气流从分离装置输送到抽吸装置的装置，以及用于将去除的材料输送到储存区的装置。

7. 发明申请

US20070190021A1 Poly(diallylamine)-based bile acid sequestrants 审中-公开
标题翻译：聚（二烯丙基胺）为基础的胆汁酸多价螯合剂
公开(公告)号：US20070190021A1
公开(公告)日：2007-08-16
申请号：US11498309
申请日：2006-08-01
申请人： Stephen Holmes-Farley , Pradeep Dhal , John Petersen
发明人： Stephen Holmes-Farley , Pradeep Dhal , John Petersen
IPC分类号： A61K31/787
CPC分类号： B82Y5/00 , A61K31/785 , A61K31/787 , A61K31/795 , A61K47/6949 , C08G61/12 , Y10S514/824
摘要： The present invention relates to a method for removing bile acids from a patient and certain polymers of use in the method. The method comprises the step of administering to the patient a therapeutically effective amount of a polymer composition which includes a a poly(diallylamine)polymer which is substituted with hydrophobic groups. The hydrophobic groups can be a substituted or unsubstituted, straight chain or branched C3-C24-alkyl group, an aralkyl group or an aryl group.
摘要翻译：本发明涉及一种从患者中除去胆汁酸的方法和本方法中使用的某些聚合物。该方法包括向患者施用治疗有效量的聚合物组合物的步骤，该聚合物组合物包括被疏水基团取代的聚（二烯丙基胺）聚合物。疏水基团可以是取代或未取代的直链或支链C 3 -C 24 - 烷基，芳烷基或芳基。

8. 发明授权

US07089047B2 Fat depth sensor 失效
标题翻译：脂肪深度传感器
公开(公告)号：US07089047B2
公开(公告)日：2006-08-08
申请号：US10173226
申请日：2002-06-13
申请人： Wayne Stephen Holmes
发明人： Wayne Stephen Holmes
IPC分类号： A61B5/00
CPC分类号： G01N33/12 , G01B15/02 , G01N22/00 , Y10S128/92
摘要： A non-invasive sensor suitable for measuring the depth of fat in animal tissue is described, the sensor generating and transmitting focussed discrete narrow band microwave signals into the tissue, receiving reflected microwave signals from the tissue and providing magnitude and phase information of the reflected microwave signals for a processor to compute a value of the fat depth within the tissue.
摘要翻译：描述了适用于测量动物组织中脂肪深度的非侵入式传感器，该传感器产生和传输聚集的离散窄带微波信号到组织中，从组织接收反射的微波信号并提供反射微波的幅度和相位信息用于处理器计算组织内的脂肪深度的值的信号。

9. 发明申请

US20050131161A1 Process for removing bile salts from a patient and alkylated compositions therefor 有权
标题翻译：从患者中除去胆汁盐的方法及其烷基化组合物
公开(公告)号：US20050131161A1
公开(公告)日：2005-06-16
申请号：US10886016
申请日：2004-07-07
申请人： W. Mandeville , Stephen Holmes-Farley
发明人： W. Mandeville , Stephen Holmes-Farley
IPC分类号： A01N33/18 , A61K20060101 , A61K31/04 , A61K31/785 , A61K31/787 , A61P1/16 , A61P3/06 , C08F8/00 , C08F8/02 , C08F8/44 , C08F16/00 , C08F18/22 , C08F26/02 , C08F116/00 , C08F220/34 , C08F220/60 , C08F283/00 , C08G69/26 , C08G73/00 , C08G73/02 , C08G81/00
CPC分类号： C08F220/60 , A61K31/785 , A61K31/787 , C08F8/00 , C08F8/02 , C08F8/44 , C08F26/00 , C08F220/34 , C08L39/02 , C08F220/00 , C08F226/02 , C08F26/02
摘要： The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically effective amount of a salt of an alkylated and crosslinked polymer. The alkylated and crosslinked polymer salt comprises the reaction product of crosslinked polymers, or salts and copolymers thereof having amine containing repeat units, with at least one aliphatic alkylating agent.
摘要翻译：本发明涉及从有需要的患者中除去胆汁盐的方法和用于该方法的组合物。该方法包括向患者施用治疗有效量的烷基化和交联聚合物的盐。烷基化和交联的聚合物盐包括具有含有重复单元的胺的交联聚合物或其盐和共聚物与至少一种脂族烷基化剂的反应产物。

10. 发明授权

US5618308A Surgical instrument capable of disassembly 失效
标题翻译：手术器械能拆卸
公开(公告)号：US5618308A
公开(公告)日：1997-04-08
申请号：US573283
申请日：1995-12-15
申请人： J. Stephen Holmes , Charles E. Beuchat
发明人： J. Stephen Holmes , Charles E. Beuchat
IPC分类号： A61B17/28 , A61B18/14 , A61B19/00
CPC分类号： A61B17/29 , A61B17/28 , A61B18/1442 , A61B2017/0046 , A61B2017/292 , A61B2017/2929 , A61B2090/0813
摘要： A surgical instrument which easily disassembles for sterilization comprises an inner rod coaxially disposed in a hollow tube with a handle at one end of the rod and a working tip at the other end. The handle is detachably interconnected to the inner rod and the inner rod is detachably interconnected to the hollow tube by the cooperation of at least one locking pin secured to the inner rod and a locking tab formed on the inner surface of the hollow tube.
摘要翻译：容易拆卸灭菌的手术器械包括同轴地设置在中空管中的内杆，杆的一端具有手柄，另一端具有工作尖端。手柄可拆卸地互连到内杆，并且内杆通过固定到内杆的至少一个锁定销和形成在中空管的内表面上的锁定突起的配合而可拆卸地互连到中空管。

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