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1. 发明申请

US20090130161A1 MATERIAL COMPOSITIONS FOR MICROBIAL AND CHEMICAL PROTECTION 失效
标题翻译：用于微生物和化学保护的材料组合物
公开(公告)号：US20090130161A1
公开(公告)日：2009-05-21
申请号：US12263782
申请日：2008-11-03
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： A01N25/10 , A01N59/16
CPC分类号： A62D5/00 , A01N59/16 , A01N59/20 , A62D9/00 , Y10S514/823 , Y10S514/974 , Y10T442/654 , A01N25/10 , A01N25/34 , A01N37/44 , A01N43/50 , A01N2300/00
摘要： An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.
摘要翻译：用于液体介质或用于结合到涂层，结构塑料材料，薄微孔膜，纺织品和海绵中的抗微生物和化学减活组合物。该组合物包括银，银与银的亚胺或亚微米颗粒及其与对羟基苯甲酸酯，氧化物，水杨酸盐，乙酸盐，柠檬酸盐，苯甲酸盐和磷酸盐的盐以及它们的铜盐和锌盐。

2. 发明申请

US20080124368A1 Composition 审中-公开
标题翻译：组成
公开(公告)号：US20080124368A1
公开(公告)日：2008-05-29
申请号：US12005109
申请日：2007-12-26
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： C09D5/16 , A01N25/00
CPC分类号： C09D5/14 , A01N25/10
摘要： An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a polyurethane resin or polyurethane hybrids, copolymers, or mixtures with other polymers such as polyesters, nitrites, PVC, and synthetic rubber latexes. The antimicrobial formulation is formed from about 60 to about 90 wt % of an antimicrobial material, about 1 to about 30 wt % calcium chelator, about 0.001 to about 2 wt % color and appearance enhancing pigments, about 0.001 to about 2 wt % of surfactants, and about 0.5 to about 10 wt % lubricant. The polyurethane resin may be a nonaqueous or aqueous latex dispersion or a prepolymer that polymerizes when exposed to moisture. An antimicrobial coating may be formed on the surface of an article by applying an antimicrobial composition to the article; if a polyurethane prepolymer is used, the composition is exposed to moisture and if an aqueous or nonaqueous dispersion is used, the water or solvent is evaporated. A coating may also be formed by making a mixture of the antimicrobial formulation and a resin and molding, overmolding, or extruding the article from the compounded mixture.
摘要翻译：抗微生物组合物由约5至约25重量％的抗微生物制剂和约75至约95重量％的聚氨酯树脂或聚氨酯混合物，共聚物或与其它聚合物如聚酯，亚硝酸盐，PVC和合成物的混合物形成橡胶胶乳。抗微生物制剂由约60至约90重量％的抗微生物材料，约1至约30重量％的钙螯合剂，约0.001至约2重量％的颜色和外观增强颜料，约0.001至约2重量％的表面活性剂，和约0.5至约10重量％的润滑剂。聚氨酯树脂可以是非水性或水性胶乳分散体或当暴露于水分时聚合的预聚物。可以通过将抗微生物组合物施用到制品上而在制品的表面上形成抗微生物涂层; 如果使用聚氨酯预聚物，则组合物暴露于水分，如果使用水性或非水性分散体，则蒸发水或溶剂。还可以通过制备抗微生物制剂和树脂的混合物并且从配混的混合物中模制，包覆成型或挤出制品来形成涂层。

3. 发明授权

US10137325B2 System and method for deactivation and disposal of a pharmaceutical dosage form 有权
公开(公告)号：US10137325B2
公开(公告)日：2018-11-27
申请号：US14667231
申请日：2015-03-24
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： A62D3/38 , B01J27/053 , B01J31/22 , B65D85/00 , B65D81/02 , A62D101/20
摘要： A system and method are provided for deactivation and disposal of a pharmaceutical dosage form. The system and method employ an oxidant and an immobilizing agent placed in a container. The pharmaceutical dosage form is placed into the container, and water is added to the container. A rapid chemical deactivation of the active ingredient or ingredients in the pharmaceutical then occurs by a chemical oxidation process. Upon contact with the water, the immobilizing agent swells or expands in volume to form a gel or slurry, binding the other components in the container within the gel or slurry, where they remain after disposal. The system can be in the form of a kit, or can be scaled up for use by municipalities or institutions.

4. 发明申请

US20170095502A1 Antimicrobial Metal-Binding Polymers 审中-公开
公开(公告)号：US20170095502A1
公开(公告)日：2017-04-06
申请号：US15287532
申请日：2016-10-06
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： A61K31/785 , A61K31/715 , A01N43/16 , A01N43/90 , A01N37/44 , A61K31/4745 , A61K31/519
CPC分类号： A61K31/795 , A01N37/44 , A61K31/4745 , A61K31/519 , A61K31/715 , A61K31/765 , A61K31/785 , A61K47/585 , A61K47/60 , A61K47/645 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/40 , A61L2300/404 , C08F8/32 , C08G65/332 , C08G65/3344 , C08G2650/32 , C08G2650/54 , C08L2203/02 , A01N25/10
摘要： An antimicrobial composition for the treatment of drug-resistant pathogens is provided. The composition includes antimicrobial compounds and chelating agents assemblies that are particularly effective in inhibiting drug-resistant bacteria and biofilm growth. Optionally, the composition may include an efflux pump inhibitor, further enhancing activity against resistant bacteria. Also provided are methods of treating diseases and surfaces of materials treated with the composition.

5. 发明申请

US20150265867A1 System and Method for Deactivation and Disposal of a Pharmaceutical Dosage Form 审中-公开
标题翻译：药物剂型失活和处置的系统和方法
公开(公告)号：US20150265867A1
公开(公告)日：2015-09-24
申请号：US14667231
申请日：2015-03-24
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： A62D3/38 , B65D81/02 , B65D85/00 , B01J31/22 , B01J27/053
CPC分类号： A62D3/38 , A62D2101/20 , B01J27/053 , B01J31/2295 , B01J2231/70 , B01J2531/842 , B65D81/02 , B65D85/70 , Y10T428/13
摘要： A system and method are provided for deactivation and disposal of a pharmaceutical dosage form. The system and method employ an oxidant and an immobilizing agent placed in a container. The pharmaceutical dosage form is placed into the container, and water is added to the container. A rapid chemical deactivation of the active ingredient or ingredients in the pharmaceutical then occurs by a chemical oxidation process. Upon contact with the water, the immobilizing agent swells or expands in volume to form a gel or slurry, binding the other components in the container within the gel or slurry, where they remain after disposal. The system can be in the form of a kit, or can be scaled up for use by municipalities or institutions.
摘要翻译：提供了用于药物剂型的失活和处理的系统和方法。该系统和方法使用放置在容器中的氧化剂和固定剂。将药物剂型放入容器中，向容器中加入水。药物中活性成分或成分的快速化学失活通过化学氧化过程进行。在与水接触时，固定剂体积膨胀或膨胀以形成凝胶或浆液，将容器中的其它组分与凝胶或浆料结合，在处理后残留。该系统可以是套件的形式，或者可以被放大以供市政机构或机构使用。

6. 发明授权

US6165366A Process for removing mercury from industrial and clinical waste water 失效
标题翻译：从工业和医疗废水中去除汞的工艺
公开(公告)号：US6165366A
公开(公告)日：2000-12-26
申请号：US431650
申请日：1999-11-01
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： C02F1/28 , C02F1/68 , C02F1/72 , C02F1/76
CPC分类号： C02F1/288 , C02F1/283 , C02F1/683 , C02F1/722 , C02F1/76 , C02F2101/20
摘要： A process is described for the removal of mercury present at levels of 1-5000 ppb in waste water discharged from clinical research laboratories, industries and hospitals. The process involves preoxidation of the influent waste water with very small amounts of hypochlorite (16-100 ppm levels)or hydrogen peroxide, in a pretreatment tank. The waste water is then serially filtered through two pre filters and four carbon columns at a flow rate of 5 bedvolumes/hr. The preoxidation, prefiltration, organic removal, heavy metals removal (second column) and polishing stages (third and fourth) are important to achieve very low levels of mercury in the effluent. The last three columns contain activated coconut shell carbon impregnated with mercaptothiazoline . The three columns of the mercaptothiazoline impregnated carbon remove mercury and other heavy metals successively and reduce their levels in the influent to very low levels that is well below the enforced limit of 1 ppb. The last column could be also filled with MCT impregnated carbon fiber. Each of the columns are topped by a 0.5 foot layer of 0.5% carbon impregnated with chlorhexidine, butyl paraben and resorcinol monoacetate to prevent biofouling.
摘要翻译：描述了从临床研究实验室，工业和医院排放的废水中去除汞含量为1-5000ppb的汞的方法。该方法包括在预处理槽中用非常少量的次氯酸盐（16-100ppm水平）或过氧化氢预处理进水废水。然后通过两个预过滤器和四个碳柱以5个床体积/小时的流速连续过滤废水。预氧化，预过滤，有机物去除，重金属去除（第二列）和抛光阶段（第三和第四）对于在流出物中实现非常低水平的汞是重要的。最后三列包含用巯基噻唑啉浸渍的活化的椰子壳碳。巯基噻唑啉浸渍碳的三列依次除去汞和其他重金属，并将其进入水平降低至非常低的水平，远低于强制限值1 ppb。最后一列也可以填充MCT浸渍碳纤维。每个柱子被浸渍有洗必太，对羟基苯甲酸丁酯和间苯二酚单乙酸盐的0.5英尺0.5％的碳酸盐覆盖，以防止生物结垢。

7. 发明授权

US5877243A Encrustation and bacterial resistant coatings for medical applications 失效
标题翻译：用于医疗应用的耐腐蚀和细菌耐受涂层
公开(公告)号：US5877243A
公开(公告)日：1999-03-02
申请号：US851306
申请日：1997-05-05
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： A61L29/00 , A61L29/08 , A61L29/12 , A61L29/16 , C08K3/08 , C08K5/00 , C08K5/092 , C08K5/17 , C08K5/5317 , C08L101/00 , C09D5/00 , C09D5/14 , C09D201/00 , C08K3/10 , C08K5/09 , C08K5/10 , C08K5/51
CPC分类号： A61L29/16 , A61L29/085 , A61L29/126 , C08K5/0058 , C08K5/092 , C08K5/175 , C08K5/5317 , C09D5/14 , A61L2300/102 , A61L2300/104 , A61L2300/21 , A61L2300/45
摘要： Disclosed are coatings and materials that resist bacterial colonization and encrustation for use in medical devices and urological applications. The coating includes acidic chelating components, reactively bound to a hydrophilic polyurethane prepolymer along with noble metal combinations or antibacterials. The acidic and noble metal combinations can also be incorporated as additives during plastic molding of medical devices. A continuous antibacterial surfaces are provided by such coatings and materials.
摘要翻译：公开了抵抗细菌定殖和结垢用于医疗装置和泌尿应用的涂层和材料。涂层包括酸性螯合组分，与亲水性聚氨酯预聚物以及贵金属组合或抗菌剂一起反应结合。酸性和贵金属组合也可以在医疗装置的塑料成型期间作为添加剂掺入。由这种涂层和材料提供连续的抗菌表面。

8. 发明授权

US5683829A Redox promoters for methonol fuel cells 失效
标题翻译：甲醇燃料电池的氧化还原促进剂
公开(公告)号：US5683829A
公开(公告)日：1997-11-04
申请号：US716915
申请日：1996-09-11
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： H01M4/90 , H01M4/92 , H01M8/10 , H01M4/86
CPC分类号： H01M4/926 , H01M4/90 , H01M4/92 , H01M2300/0082 , H01M4/9008 , H01M8/1007 , H01M8/1009
摘要： The invention refers to a fuel cell electrode for oxidation preferably methanol or methanol reformate in a fuel cell with acid electrolytes. The electrode material comprises of a) carbons modified by the chemisorption or covalent attachment of metallocomplexes, over which a noble metal catalyst such as platinum is deposited, b) carbon-noble metal systems mixed with metallocomplexes, and c) mixtures of noble metal blacks and metallocomplexes. An improvement of 100-200 mV is seen over controls using platinum alone in full tests using methanol and oxygen or air. The advantages of using the disclosed promoters is the use of low loaded (20% Pt on carbon) electrodes rather than pure noble metal or alloy blacks.
摘要翻译：本发明涉及用于氧化的燃料电池电极，优选在具有酸性电解质的燃料电池中甲醇或甲醇重整产物。电极材料包括a）通过金属络合物的化学吸附或共价连接而改性的碳，沉积贵金属催化剂如铂，b）与金属络合物混合的碳 - 贵金属体系，和c）贵金属黑和金属络合物。在使用甲醇和氧气或空气的全面测试中，单独使用铂的对照可以看到100-200 mV的改善。使用所公开的促进剂的优点是使用低负载（20％Pt碳）电极而不是纯贵金属或合金黑。

9. 发明授权

US08192765B2 Material compositions for microbial and chemical protection 失效
标题翻译：用于微生物和化学防护的材料组成
公开(公告)号：US08192765B2
公开(公告)日：2012-06-05
申请号：US12263782
申请日：2008-11-03
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： A01N25/12 , A01N25/34 , A01N55/02 , A01N59/00 , A01N59/16 , A01N59/20
CPC分类号： A62D5/00 , A01N59/16 , A01N59/20 , A62D9/00 , Y10S514/823 , Y10S514/974 , Y10T442/654 , A01N25/10 , A01N25/34 , A01N37/44 , A01N43/50 , A01N2300/00
摘要： An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.
摘要翻译：用于液体介质或用于结合到涂层，结构塑料材料，薄微孔膜，纺织品和海绵中的抗微生物和化学减活组合物。该组合物包括银，银与银的亚胺或亚微米颗粒及其与对羟基苯甲酸酯，氧化物，水杨酸盐，乙酸盐，柠檬酸盐，苯甲酸盐和磷酸盐的盐以及它们的铜盐和锌盐。

10. 发明申请

US20050048124A1 Antimicrobial composition for medical articles 有权
标题翻译：医疗用品的抗微生物组合物
公开(公告)号：US20050048124A1
公开(公告)日：2005-03-03
申请号：US10925631
申请日：2004-08-25
申请人： Shantha Sarangapani
发明人： Shantha Sarangapani
IPC分类号： A61K31/555 , A61K33/38 , A61K45/06 , A61K7/021
CPC分类号： A61K45/06 , A61K31/555 , A61K33/38 , Y10S514/836 , A61K2300/00
摘要： An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a silicone resin. The antimicrobial formulation is formed from about 60 to about 95 wt % of an antimicrobial material, about 1 to about 30 wt % calcium chelator, about 0.001 to about 0.25 wt % pigment, and about 0.5 to about 3.5 wt % lubricant. The silicone resin may be a dispersion of about 40 to about 60 w/v % of an RTV silicone resin in a solvent, a liquid silicone resin, or a solid silicone resin. An antimicrobial coating may be formed on the surface of an article by applying an antimicrobial composition to the article and permitting the solvent to evaporate. It may also be formed by making a mixture of about 5 to about 12 wt % of an antimicrobial formulation and about 88 to about 95 wt % of a liquid or solid silicone resin and molding, overmolding, or extruding the article from the compounded mixture.
摘要翻译：抗微生物组合物由约5至约25重量％的抗微生物制剂和约75至约95重量％的有机硅树脂形成。抗微生物制剂由约60至约95重量％的抗微生物材料，约1至约30重量％的钙螯合剂，约0.001至约0.25重量％的颜料和约0.5至约3.5重量％的润滑剂形成。有机硅树脂可以是溶剂中的约40至约60w / v％的RTV硅树脂的分散体，液体硅树脂或固体有机硅树脂。通过将抗微生物组合物施用于制品并允许溶剂蒸发，可以在制品的表面上形成抗微生物涂层。还可以通过制备约5至约12重量％的抗微生物制剂和约88至约95重量％的液体或固体有机硅树脂的混合物并从混合的混合物中模制，包覆成型或挤出制品而形成。

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