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    • 3. 发明申请
    • Curing and prophylactic agent applied during the use of alcohol and psychoactive substances
    • 在使用酒精和精神活性物质时应用固化和预防剂
    • US20060148898A1
    • 2006-07-06
    • US11322156
    • 2005-12-29
    • Sergei ZenovichBoris Strelets
    • Sergei ZenovichBoris Strelets
    • A61K31/19A61K31/185
    • A61K31/19A61K31/095A61K31/185
    • The invention relates to medicine and is directed at developing means and methods for narcological practice and for preventive measures in order to reduce the risk of falling sick with such menacing modem diseases like dependence diseases, in particular alcoholism, narcomania and toximania. Said invention provides for using already known chemical compounds, i.e. vicinal dithioglycols for developing medical agents exhibiting properties for preventing contraction or development or reducing the speed of pathological processes forming a base for dependence diseases, in particular withdrawal syndromes. The inventive substances reduce or block pharmacological effects resulting from ethanol injection and/or narcotics, thereby directly influencing pathogenic mechanisms of the dependence diseases, in particular alcoholism. It is stated that said agents are particularly efficient when they are perorally administered. Said invention is accompanied by experimental material which proves the large perspective of the inventive agents and of a prophylactic method which provides for the use thereof before and after consuming alcohol-containing beverages or narcotics. The use of the invention makes it possible to reduce the degree of falling sick with alcoholism and narcomania and to reduce the toxic action of alcohols during the household use thereof.
    • 本发明涉及医学,并且旨在开发用于麻醉实践和预防措施的手段和方法,以便降低诸如依赖性疾病,特别是酒精中毒,粘虫和蛔虫之类的威胁性现代疾病而患病的风险。 所述发明提供使用已知的化学化合物,即邻位二硫代二醇用于开发具有预防收缩或发育的特性的药物,或降低形成依赖性疾病的基础,特别是戒断综合症的病理过程的速度。 本发明的物质降低或阻断由乙醇注射和/或麻醉剂引起的药理作用,从而直接影响依赖性疾病,特别是酒精中毒的致病机制。 据说所述试剂在经口给药时是特别有效的。 本发明伴随着实验材料,其证明本发明试剂的大视角以及在饮用含酒精饮料或麻醉剂之前和之后提供其用途的预防方法。 通过使用本发明,可以降低酗酒和呕吐患病的程度,并降低醇在家庭使用中的毒性作用。