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1. 发明授权

US08167932B2 Heart valve delivery system with valve catheter 有权
标题翻译：带阀导管的心脏瓣膜输送系统
公开(公告)号：US08167932B2
公开(公告)日：2012-05-01
申请号：US11252657
申请日：2005-10-18
申请人： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Iobbi , Rajesh Khanna , Dave J. Evans
发明人： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Iobbi , Rajesh Khanna , Dave J. Evans
IPC分类号： A61F2/24 , A61F2/06
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9583
摘要： A heart valve delivery system is provided wherein a prosthetic valve is carried on a valve catheter inside a delivery sleeve. A step balloon protrudes from the delivery sleeve and provides a tapered surface for facilitating advancement through a body vessel. The step balloon also aids in crossing the leaflets of a native valve. After the prosthetic valve is positioned within the native valve, the delivery sleeve is retracted to expose the prosthetic valve. In one embodiment, the delivery sleeve is retracted by the use of a lead screw, which effectuates relative movement between the valve catheter and delivery sleeve. The prosthetic valve is preferably self-expandable. If necessary, the step balloon may be expanded to securely seat the prosthetic valve at the site of the native valve. The prosthetic valve is preferably coupled to the valve catheter by a plurality of flexible extension arms which allow the prosthetic valve to be collapsed after initial deployment such that the prosthetic valve may be repositioned if necessary.
摘要翻译：提供心脏瓣膜输送系统，其中人造瓣膜被携带在输送套筒内的阀导管上。步进气球从输送套筒突出并提供锥形表面，以便于通过身体血管进入。阶梯气球还有助于穿过天然瓣膜的小叶。在人工瓣膜定位在天然瓣膜内之后，输送套筒缩回以露出假体瓣膜。在一个实施例中，输送套筒通过使用导螺杆缩回，其实现了阀导管和输送套筒之间的相对运动。假体瓣膜优选是可自膨胀的。如果需要，可以扩展踏板气囊以将人工瓣膜牢固地安置在天然瓣膜的位置。假体瓣膜优选地通过多个柔性延伸臂联接到瓣膜导管，所述多个柔性延伸臂允许假肢瓣膜在初始部署之后被折叠，使得如果必要，可以重新定位假体瓣膜。

2. 发明申请

US20120209375A1 STABILITY DEVICE FOR USE WITH PERCUTANEOUS DELIVERY SYSTEMS 审中-公开
标题翻译：使用PERCUTANEOUS交付系统的稳定性设备
公开(公告)号：US20120209375A1
公开(公告)日：2012-08-16
申请号：US13370215
申请日：2012-02-09
申请人： Gilbert Madrid , Matthew T. Winston , Sam Sok , Thanh Huy Le , Tri D. Tran , Kim Le
发明人： Gilbert Madrid , Matthew T. Winston , Sam Sok , Thanh Huy Le , Tri D. Tran , Kim Le
IPC分类号： A61M25/092 , A61F2/24
CPC分类号： A61F2/2427 , A61F2/2412 , A61F2/2433 , A61F2002/9583 , A61M25/0051 , A61M25/0052 , A61M25/0147 , A61M25/1011
摘要： A delivery system for stabilizing a catheter shaft across an aortic arch can include one or more stabilizing members configured to fix or stabilize the position of the catheter relative to the aortic arch of a patient.
摘要翻译：用于使穿过主动脉弓的导管轴稳定的递送系统可以包括一个或多个稳定构件，其被配置成固定或稳定导管相对于患者主动脉弓的位置。

3. 发明申请

US20150182334A1 HEART VALVE DELIVERY SYSTEM WITH VALVE CATHETER 有权
标题翻译：带阀门的心瓣输送系统
公开(公告)号：US20150182334A1
公开(公告)日：2015-07-02
申请号：US14561113
申请日：2014-12-04
申请人： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Gabriel Iobbi , David J. Evans , Rajesh A. Khanna
发明人： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Gabriel Iobbi , David J. Evans , Rajesh A. Khanna
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9583
摘要： A heart valve delivery system is provided wherein a prosthetic valve is carried on a valve catheter inside a delivery sleeve. A step balloon protrudes from the delivery sleeve and provides a tapered surface for facilitating advancement through a body vessel. The step balloon also aids in crossing the leaflets of a native valve. After the prosthetic valve is positioned within the native valve, the delivery sleeve is retracted to expose the prosthetic valve. If necessary, the step balloon may be expanded to securely seat the prosthetic valve at the site of the native valve. The prosthetic valve is preferably coupled to the valve catheter by a plurality of flexible extension arms which allow the prosthetic valve to be collapsed after initial deployment such that the prosthetic valve may be repositioned if necessary.
摘要翻译：提供心脏瓣膜输送系统，其中人造瓣膜被携带在输送套筒内的阀导管上。步进气球从输送套筒突出并提供锥形表面，以便于通过身体血管进入。阶梯气球还有助于穿过天然瓣膜的小叶。在人工瓣膜定位在天然瓣膜内之后，输送套筒缩回以露出假体瓣膜。如果需要，可以扩展踏板气囊以将人工瓣膜牢固地安置在天然瓣膜的位置。假体瓣膜优选地通过多个柔性延伸臂联接到瓣膜导管，所述多个柔性延伸臂允许假肢瓣膜在初始部署之后被折叠，使得如果必要，可以重新定位假体瓣膜。

4. 发明申请

US20120290078A1 HEART VALVE DELIVERY SYSTEM WITH VALVE CATHETER 审中-公开
标题翻译：带阀门的心瓣输送系统
公开(公告)号：US20120290078A1
公开(公告)日：2012-11-15
申请号：US13449200
申请日：2012-04-17
申请人： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Iobbi , Rajesh Khanna , Dave J. Evans
发明人： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Iobbi , Rajesh Khanna , Dave J. Evans
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9517 , A61F2002/9583
摘要： A heart valve delivery system is provided wherein a prosthetic valve is carried on a valve catheter inside a tubular delivery sleeve. The valve catheter has a distal end coupled to a mop. The mop comprises a plurality of flexible extensions configured for releasable attachment to the prosthetic valve. A lead screw nut is coupled to a proximal end of the tubular delivery sleeve and a lead screw is coupled to the valve catheter. The lead screw engages the lead screw nut and rotation of the lead screw causes the delivery sleeve to retract relative to the valve catheter and the prosthetic valve for exposing the prosthetic valve. The flexible extensions of the mop allow expansion of the valve while maintaining the attachment during placement of the valve at a native valve site.
摘要翻译：提供心脏瓣膜输送系统，其中人造瓣膜被承载在管状输送套筒内的阀导管上。阀导管具有与拖把相连的远端。拖把包括多个柔性延伸部，其构造成用于可释放地附接到人工瓣膜。导螺杆螺母联接到管状输送套筒的近端，并且导螺杆联接到瓣膜导管。导螺杆与导螺杆螺母接合并且导螺杆的旋转使得输送套筒相对于阀导管和用于暴露人造瓣膜的假肢瓣缩回。拖把的柔性延伸部件可以在将瓣膜置于自然瓣膜部位的同时保持附件的同时扩张阀。

5. 发明申请

US20110144742A1 Expansion Device for Treatment of Vascular Passageways 审中-公开
标题翻译：用于治疗血管通道的扩张装置
公开(公告)号：US20110144742A1
公开(公告)日：2011-06-16
申请号：US12969187
申请日：2010-12-15
申请人： Gilbert Madrid , Matthew Winston , Sam Sok , Michael D. Franklin
发明人： Gilbert Madrid , Matthew Winston , Sam Sok , Michael D. Franklin
IPC分类号： A61F2/24 , A61M29/00
CPC分类号： A61F2/2433 , A61B2017/22098 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/243 , A61M25/10 , A61M25/1002 , A61M25/1011
摘要： A delivery system for delivering an expandable member to a treatment location includes an elongate shaft and an expandable member coupled to a distal end of the elongate shaft. The expandable member is moveable between a collapsed configuration and an expanded configuration, and has an inner expandable member and a plurality of outer expandable members that at least partially surround the inner expandable member.
摘要翻译：用于将可扩展构件递送到治疗位置的递送系统包括细长轴和联接到细长轴的远端的可扩张构件。可膨胀构件可在收缩构型和膨胀构型之间移动，并且具有至少部分地围绕内部可膨胀构件的内部可扩张构件和多个外部可扩张构件。

6. 发明申请

US20140371847A1 EXPANSION DEVICE AND METHOD FOR TREATING VASCULAR PASSAGEWAYS 有权
标题翻译：膨胀装置和治疗血管通路的方法
公开(公告)号：US20140371847A1
公开(公告)日：2014-12-18
申请号：US14475341
申请日：2014-09-02
申请人： Gilbert Madrid , Matthew T. Winston , Sam Sok , Michael D. Franklin
发明人： Gilbert Madrid , Matthew T. Winston , Sam Sok , Michael D. Franklin
IPC分类号： A61F2/24
CPC分类号： A61F2/2433 , A61B2017/22098 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/243 , A61M25/10 , A61M25/1002 , A61M25/1011
摘要： Method for delivering an expandable member to a treatment location includes an elongate shaft and an expandable member coupled to a distal end of the elongate shaft. Embodiments of the expandable member are moveable between a collapsed configuration and an expanded configuration, and have an inner expandable member and a plurality of outer expandable members that at least partially surround the inner expandable member, and are suitable for delivering prosthetic heart valves and performing vavuloplasties.
摘要翻译：用于将可扩张构件递送到治疗位置的方法包括细长轴和联接到细长轴的远端的可扩张构件。可膨胀构件的实施例可在塌缩构型和膨胀构型之间移动，并且具有至少部分地围绕内部可膨胀构件的内部可膨胀构件和多个外部可扩张构件，并且适合于递送假体心脏瓣膜并执行瓣膜成形。

7. 发明申请

US20070088431A1 Heart valve delivery system with valve catheter 有权
标题翻译：带阀导管的心脏瓣膜输送系统
公开(公告)号：US20070088431A1
公开(公告)日：2007-04-19
申请号：US11252657
申请日：2005-10-18
申请人： Henry Bourang , Thanh Le , David Taylor , Sam Sok , Mario Iobbi , Rajesh Khanna , Dave Evans
发明人： Henry Bourang , Thanh Le , David Taylor , Sam Sok , Mario Iobbi , Rajesh Khanna , Dave Evans
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9583
摘要： A heart valve delivery system is provided wherein a prosthetic valve is carried on a valve catheter inside a delivery sleeve. A step balloon protrudes from the delivery sleeve and provides a tapered surface for facilitating advancement through a body vessel. The step balloon also aids in crossing the leaflets of a native valve. After the prosthetic valve is positioned within the native valve, the delivery sleeve is retracted to expose the prosthetic valve. In one embodiment, the delivery sleeve is retracted by the use of a lead screw, which effectuates relative movement between the valve catheter and delivery sleeve. The prosthetic valve is preferably self-expandable. If necessary, the step balloon may be expanded to securely seat the prosthetic valve at the site of the native valve. The prosthetic valve is preferably coupled to the valve catheter by a plurality of flexible extension arms which allow the prosthetic valve to be collapsed after initial deployment such that the prosthetic valve may be repositioned if necessary.
摘要翻译：提供心脏瓣膜输送系统，其中人造瓣膜被携带在输送套筒内的阀导管上。步进气球从输送套筒突出并提供锥形表面，以便于通过身体血管进入。阶梯气球还有助于穿过天然瓣膜的小叶。在人工瓣膜定位在天然瓣膜内之后，输送套筒缩回以露出假体瓣膜。在一个实施例中，输送套筒通过使用导螺杆缩回，其实现了阀导管和输送套筒之间的相对运动。假体瓣膜优选是可自膨胀的。如果需要，可以扩展踏板气囊以将人工瓣膜牢固地安置在天然瓣膜的位置。假体瓣膜优选地通过多个柔性延伸臂联接到瓣膜导管，所述多个柔性延伸臂允许假肢瓣膜在初始部署之后被折叠，使得如果必要，可以重新定位假体瓣膜。

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