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1. 发明申请

US20080060660A1 Systems and methods for moving and/or restraining tissue in the upper respiratory system 失效
标题翻译：用于在上呼吸系统中移动和/或抑制组织的系统和方法
公开(公告)号：US20080060660A1
公开(公告)日：2008-03-13
申请号：US11980120
申请日：2007-10-30
申请人： Lionel Nelson , Ronald Lax , Eric Doelling
发明人： Lionel Nelson , Ronald Lax , Eric Doelling
IPC分类号： A61F5/56
CPC分类号： A61F2/20 , A61F2/00 , A61F5/566 , A61F2210/009 , Y10S602/902
摘要： Systems and methods place a first magnetically interactive material in or on a tongue in an airway. The systems and methods place a second magnetically interactive material in or on tissue in a desired relationship with the tongue. The first and second materials magnetically interact to stabilize a preferred orientation of the tongue.
摘要翻译：系统和方法在气道中的舌头中或舌上放置第一磁性交互材料。系统和方法将第二磁性交互材料放置在与舌头有关的组织中或组织上。第一和第二材料磁性相互作用以稳定舌头的优选取向。

2. 发明申请

US20070102004A1 Systems and methods for moving and/or restraining tissue in the upper respiratory system 有权
标题翻译：用于在上呼吸系统中移动和/或抑制组织的系统和方法
公开(公告)号：US20070102004A1
公开(公告)日：2007-05-10
申请号：US11637382
申请日：2006-12-12
申请人： Lionel Nelson , Ronald Lax , Eric Doelling
发明人： Lionel Nelson , Ronald Lax , Eric Doelling
IPC分类号： A61F5/56
CPC分类号： A61F2/20 , A61F2/00 , A61F5/566 , A61F2210/009 , Y10S602/902
摘要： Systems and methods selectively stabilize tissue in the oral cavity. The systems and methods provide a first material sized and configured to be fitted to less mobile tissue in the oral cavity, e.g., the roof of the mouth or upper/lower teeth. The systems and methods provide a second material sized and configured to be releasably fitted to more mobile tissue in the oral cavity, e.g., a region of the tongue. The second material is magnetically attracted toward the first material to stabilize a preferred tissue orientation. During sleep, the systems and methods restrain movement of the more mobile tissue within the oral cavity toward positions in which snoring and/or sleep apnea events can occur, but are capable of otherwise leaving the tongue unaffected during waking hours.
摘要翻译：系统和方法选择性地稳定口腔中的组织。所述系统和方法提供尺寸和构造成适合于口腔中较少移动组织的第一材料，例如口腔顶部或上/下牙齿。系统和方法提供了尺寸和构造成可释放地装配到口腔（例如舌头区域）中的更多移动组织的第二材料。第二材料被磁吸引到第一材料以稳定优选的组织取向。在睡眠期间，系统和方法抑制口腔内更多移动组织朝向可能发生打鼾和/或睡眠呼吸暂停事件的位置的移动，但是在醒来时间期间能够使舌头不受影响。

3. 发明申请

US20060270889A1 Systems and methods for moving and/or restraining tissue in the oral cavity 审中-公开
标题翻译：用于在口腔内移动和/或限制组织的系统和方法
公开(公告)号：US20060270889A1
公开(公告)日：2006-11-30
申请号：US11483457
申请日：2006-07-10
申请人： Lionel Nelson , Ronald Lax , Eric Doelling
发明人： Lionel Nelson , Ronald Lax , Eric Doelling
IPC分类号： A61N2/00
CPC分类号： A61F5/566
摘要： Systems and related methods stabilize tissue in an airway using material which is sized and configured to be fitted to surface tissue in the airway and which is magnetically attracted toward a magnetized material to stabilize a preferred tissue orientation. The systems and related methods can be used, e.g., to treat snoring and other sleep related disorders.
摘要翻译：系统和相关方法使用尺寸和构造成适合于气道中的表面组织并且被磁吸引到磁化材料以稳定优选的组织取向的材料来稳定气道中的组织。可以使用系统和相关方法，例如来治疗打鼾和其它与睡眠有关的障碍。

4. 发明授权

US07081125B2 Universal introducer 有权
公开(公告)号：US07081125B2
公开(公告)日：2006-07-25
申请号：US10795955
申请日：2004-03-08
申请人： Stuart D. Edwards , Ronald Lax , Theodore L. Parker , Thomas C. Wehman , Theodore Kucklick
发明人： Stuart D. Edwards , Ronald Lax , Theodore L. Parker , Thomas C. Wehman , Theodore Kucklick
IPC分类号： A61B17/08 , A61B18/18
CPC分类号： A61B17/00491 , A61B17/0057 , A61B17/3415 , A61B18/14 , A61B18/1482 , A61B18/1487 , A61B2017/00084 , A61B2017/00495 , A61B2017/005 , A61B2017/00637 , A61B2017/0065 , A61B2017/00672 , A61B2017/3441 , A61B2017/3492 , A61B2018/0063 , A61B2090/064 , A61M25/0662
摘要： A device for introducing a catheter into a vessel through a puncture in a vessel and for sealing the puncture. The device includes an elongated body having a proximal end and a distal end sized to be positioned within a tissue site which includes the puncture. The elongated body includes a utility lumen sized to allow a catheter to be delivered through the utility lumen. The utility lumen is positioned within the elongated body so positioning the elongated body within the tissue site allows a catheter delivered through the utility lumen to enter the vessel. The elongated body also includes a closure lumen having an entrance port. A closure composition can be delivered through the entrance port into the closure lumen. The closure lumen also includes an exit port adjacent the distal end of the elongated body. The closure composition delivered into the closure lumen can be delivered through the exit port to the tissue site adjacent the puncture.

5. 发明申请

US20050245926A1 Sphincter treatment apparatus 失效
标题翻译：括约肌治疗仪
公开(公告)号：US20050245926A1
公开(公告)日：2005-11-03
申请号：US11175471
申请日：2005-07-06
申请人： Stuart Edwards , David Utley , Ronald Lax , Theodore Kucklick , Peter Muller
发明人： Stuart Edwards , David Utley , Ronald Lax , Theodore Kucklick , Peter Muller
IPC分类号： A61B18/00 , A61B18/14
CPC分类号： A61B18/14 , A61B17/32 , A61B18/1477 , A61B18/1492 , A61B18/1815 , A61B2018/00011 , A61B2018/00029 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00494 , A61B2018/00553 , A61B2018/00577 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/00916 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1472 , A61B2018/183 , A61B2090/3614 , A61B2090/3782
摘要： A sphincter treatment apparatus includes an energy delivery device introduction member including a proximal end with a first radius of curvature and a distal end with a second radius of curvature. The introduction member is configured to be introduced into the sphincter in a non-deployed state and to be expanded to a deployed state to at least partially expand the sphincter or an adjoining structure. An energy delivery device is coupled to the introduction member. A retainer member is coupled to the energy delivery device introduction member and configured to controllably position the introduction member in an orifice of the sphincter.
摘要翻译：括约肌治疗装置包括能量输送装置导入构件，其包括具有第一曲率半径的近端和具有第二曲率半径的远端。引入构件被配置为以非展开状态引入括约肌并且被扩展到展开状态以至少部分地扩展括约肌或相邻结构。能量输送装置联接到引入构件。保持器构件联接到能量输送装置引入构件并构造成将引导构件可控地定位在括约肌的孔中。

6. 发明申请

US20050203503A1 Infusion array ablation apparatus 审中-公开
标题翻译：输液阵列消融装置
公开(公告)号：US20050203503A1
公开(公告)日：2005-09-15
申请号：US11034503
申请日：2005-01-12
申请人： Stuart Edwards , James Baker , Hugh Sharkey , Ronald Lax
发明人： Stuart Edwards , James Baker , Hugh Sharkey , Ronald Lax
IPC分类号： A61B17/00 , A61B18/00 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/22 , A61M3/02 , A61M25/00 , A61N1/40 , A61N5/04 , C22C1/04 , C22C14/00 , C22F1/18
摘要： An infusion array ablation apparatus includes an elongated delivery device having a lumen and an infusion array positionable in the lumen. The infusion array includes an RF electrode and at least a first and a second infusion member. Each infusion member has a tissue piercing distal portion and an infusion lumen. At least one of the first or second infusion members is positionable in the elongated delivery device in a compacted state and deployable from the elongated delivery device with curvature in a deployed state. Also, at least one of the first or second infusion members exhibits a changing direction of travel when advanced from the elongated delivery device to a selected tissue site. At least one infusion port is coupled to one of the elongated delivery device, the infusion array, the first infusion member or the second infusion member.
摘要翻译：输液阵列消融装置包括细长递送装置，其具有可定位在内腔中的内腔和输液排列。输注阵列包括RF电极和至少第一和第二输注构件。每个输注构件具有组织穿刺远端部分和输注腔。第一或第二输注构件中的至少一个可以处于压实状态的细长输送装置中定位并且可以从伸长的输送装置以部署状态的曲率展开。此外，第一或第二输注构件中的至少一个表现出当从细长递送装置前进到选定的组织部位时改变的行进方向。至少一个输注端口连接到细长递送装置，输注阵列，第一输注构件或第二输注构件中的一个。

7. 发明授权

US06325798B1 Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions 有权
标题翻译：真空辅助系统和治疗括约肌和邻近组织区域的方法
公开(公告)号：US06325798B1
公开(公告)日：2001-12-04
申请号：US09304743
申请日：1999-05-04
申请人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin , Ronald Lax
发明人： Stuart Edwards , John Gaiser , David Utley , Scott West , Jay Chin , Ronald Lax
IPC分类号： A61B1818
CPC分类号： A61B18/1206 , A61B18/12 , A61B18/1477 , A61B18/1485 , A61B18/1492 , A61B2017/22067 , A61B2017/308 , A61B2017/3488 , A61B2018/00011 , A61B2018/00029 , A61B2018/00077 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00267 , A61B2018/00273 , A61B2018/00285 , A61B2018/00291 , A61B2018/00553 , A61B2018/00654 , A61B2018/0066 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00875 , A61B2018/00898 , A61B2018/046 , A61B2018/1425 , A61B2018/1475 , A61B2090/036 , A61B2090/3782 , A61B2218/002 , A61B2218/007
摘要： Systems and methods treat a tissue region at or near a sphincter by deploying a carrier, which carries an electrode that can be advanced to penetrate tissue. Negative pressure is applied through a suction port on the carrier near the electrode, to draw tissue in the tissue region inward against the carrier. The systems and methods advance the electrode to penetrate tissue drawn against the carrier. The vacuum anchors the surrounding tissue and mediates against the “tenting” of tissue during electrode penetration. Without tenting, the electrode penetrates mucosal tissue fully, to obtain a desired depth of penetration.
摘要翻译：系统和方法通过展开携带可以被推进穿透组织的电极的载体来处理括约肌处或附近的组织区域。通过电极附近的载体上的吸入口施加负压，将组织区域中的组织向内抵靠载体。这些系统和方法使电极移动以穿透抵靠载体的组织。真空锚定周围的组织，并在电极穿透期间抵抗组织的“隆起”进行介导。没有隆起，电极完全渗透粘膜组织，以获得所需的穿透深度。

8. 发明授权

US5820580A Method for ablating interior sections of the tongue 失效
标题翻译：消融舌内部的方法
公开(公告)号：US5820580A
公开(公告)日：1998-10-13
申请号：US726070
申请日：1996-10-03
申请人： Stuart D. Edwards , Ronald Lax , David Douglass
发明人： Stuart D. Edwards , Ronald Lax , David Douglass
IPC分类号： A61B17/00 , A61B17/24 , A61B18/00 , A61B18/14 , A61B18/18 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/39
CPC分类号： A61N1/403 , A61B18/1477 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N5/045 , A61B17/24 , A61B2017/00026 , A61B2018/00011 , A61B2018/00023 , A61B2018/00261 , A61B2018/00666 , A61B2018/00678 , A61B2018/00708 , A61B2018/00744 , A61B2018/00791 , A61B2018/00875 , A61B2018/1425 , A61B2090/3782 , A61M2025/0096 , A61N5/04
摘要： A method for reducing a volume of a tongue provides a source of ablation energy and an ablation energy delivery device. At least a portion of the ablation energy delivery device is positioned in an interior of the tongue. A sufficient amount of energy is delivered from the energy delivery device into the interior of the tongue to debulk a section of the tongue without damaging a hypoglossal nerve. Thereafter, the at least portion of the ablation energy delivery device is removed from the interior of the tongue.
摘要翻译：用于减小舌头体积的方法提供消融能量源和消融能量输送装置。消融能量输送装置的至少一部分位于舌头的内部。足够量的能量从能量输送装置输送到舌头的内部，以减少舌头的一部分而不损伤舌下神经。此后，消融能量输送装置的至少部分从舌头的内部移除。

9. 发明申请

US20070272257A1 Magnetic force devices, systems, and methods for resisting tissue collapse within the pharyngeal conduit 有权
公开(公告)号：US20070272257A1
公开(公告)日：2007-11-29
申请号：US11888530
申请日：2007-08-01
申请人： Lionel Nelson , Ronald Lax , Eric Doelling , Jinfang Liu , Peter Muller , Ryan Boucher , Michael Reo
发明人： Lionel Nelson , Ronald Lax , Eric Doelling , Jinfang Liu , Peter Muller , Ryan Boucher , Michael Reo
IPC分类号： A61F5/56 , A61B19/00
CPC分类号： A61F2/00 , A61B2017/248 , A61F2/0077 , A61F2/20 , A61F5/56 , A61F5/566 , A61F2210/009 , A61N2/004 , A61N2/06 , Y10S602/902
摘要： Devices, systems and methods employ magnetic force to resist tissue collapse in targeted pharyngeal structures and individual anatomic components within the pharyngeal conduit during sleep.

10. 发明申请

US20070270631A1 Magnetic force devices, systems, and methods for resisting tissue collapse within the pharyngeal conduit 审中-公开
标题翻译：磁力装置，系统和抵抗咽管内组织塌陷的方法
公开(公告)号：US20070270631A1
公开(公告)日：2007-11-22
申请号：US11888444
申请日：2007-08-01
申请人： Lionel Nelson , Ronald Lax , Eric Doelling , Jinfang Liu , Peter Muller , Ryan Boucher , Michael Reo
发明人： Lionel Nelson , Ronald Lax , Eric Doelling , Jinfang Liu , Peter Muller , Ryan Boucher , Michael Reo
IPC分类号： A61N2/10
CPC分类号： A61F2/00 , A61F2/0077 , A61F5/566 , A61F2210/009 , A61N2/004 , A61N2/06 , Y10S602/902
摘要： Devices, systems and methods employ magnetic force to resist tissue collapse in targeted pharyngeal structures and individual anatomic components within the pharyngeal conduit during sleep.
摘要翻译：装置，系统和方法采用磁力来抵抗睡眠期间咽喉导管内目标咽结构和个体解剖组件的组织塌陷。

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