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1. 发明申请

US20210030766A1 PROSTAMIDE-CONTAINING INTRAOCULAR IMPLANTS AND METHODS OF USE THEREOF 有权
公开(公告)号：US20210030766A1
公开(公告)日：2021-02-04
申请号：US16832700
申请日：2020-03-27
申请人： Alazar N. Ghebremeskel , Michael R. Robinson
发明人： Alazar N. Ghebremeskel , Michael R. Robinson
IPC分类号： A61K31/5575 , A61F9/00 , A61K31/165 , A61K9/00 , A61K47/10 , A61K47/34 , A61K9/16
摘要： Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle. Methods for making and using the implants to reduce ocular hypertension and intraocular pressure in a patient are described.

2. 发明申请

US20190281094A1 Application Program and Related Techniques for Organizing a Meeting Between People 审中-公开
公开(公告)号：US20190281094A1
公开(公告)日：2019-09-12
申请号：US16420644
申请日：2019-05-23
申请人： David R. Robinson
发明人： David R. Robinson
IPC分类号： H04L29/06 , H04W4/021 , G06Q10/10 , H04L12/18 , G06F3/0481 , G06F3/0484 , H04W4/21
摘要： A computer-implemented application program comprises various graphic user interfaces to facilitate the formation of a physical meeting between people. A computer-readable storage medium comprises instructions to implement the computer-implemented application program.

3. 发明授权

US09811855B1 Electronic extension requests to extend electronic bidding for qualified bidders for computer-based auctioning of basic generation services 有权
公开(公告)号：US09811855B1
公开(公告)日：2017-11-07
申请号：US13545367
申请日：2012-07-10
申请人： Anthony R. Robinson , Frederick W. Lark , Eugene Meehan , Chantale LaCasse , David Salant , Colin J. Loxley , Gerald W. Schirra , Robert Taylor
发明人： Anthony R. Robinson , Frederick W. Lark , Eugene Meehan , Chantale LaCasse , David Salant , Colin J. Loxley , Gerald W. Schirra , Robert Taylor
IPC分类号： G06Q30/00 , G06Q30/08 , G06Q30/06
CPC分类号： G06Q30/08 , G06Q10/00 , G06Q30/06 , G06Q30/0601 , G06Q40/04
摘要： A system and method of conducting a computer-based, simultaneous, multiple round, descending clock auction for basic generation services (BGS) includes receiving bids by an application server host application for processing bids according to auction rules, for tranche units of BGS products, calculating next round prices, and sending round results to bidders, the subsequent round prices and a notice of the number of tranches bid during the previous round and/or the amount of excess supply offered. When available to a bidder, an extension request may be automatically granted extending the duration of the round and allowing all qualified bidders to submit new bids, and thereafter deducting the number of extensions available to the bidder. When the number of tranches bid are equal to or less than a certain threshold for each of the products, the auction may end and bidders are awarded an ending price for each of the products won.

4. 发明授权

US09205493B1 Production of nanostructures 有权
标题翻译：生产纳米结构
公开(公告)号：US09205493B1
公开(公告)日：2015-12-08
申请号：US13537011
申请日：2012-06-28
申请人： Michael Eugene Young , Arjun Srinivas , Matthew R. Robinson , Alexander Chow Mittal
发明人： Michael Eugene Young , Arjun Srinivas , Matthew R. Robinson , Alexander Chow Mittal
IPC分类号： B22F9/24 , B82Y40/00
CPC分类号： B22F9/24 , B22F1/0025 , B22F2999/00 , B82Y40/00 , B22F2202/01 , B22F2203/11
摘要： Nanostructure morphologies are controlled by incorporating an agitation mechanism that imparts low shear mixing along with purification of a resulting nanostructure product to effectively remove agglomerates and other components of a reaction mixture. In such manner, higher yields and higher batch-to-batch consistency in the production of nanostructures can be achieved.
摘要翻译：纳米结构形态通过引入搅拌机制来控制，该搅拌机构与所得纳米结构产物的纯化一起产生低剪切混合，以有效地除去反应混合物中的附聚物和其它组分。以这种方式，可以实现在纳米结构生产中更高的产率和更高的批次间的一致性。

5. 发明申请

US20150052513A1 LIVE DATA AS A SERVICE AND CORRESPONDING PROGRAMMING INFRASTRUCTURE 审中-公开
标题翻译：实时数据作为服务和相应的编程基础设施
公开(公告)号：US20150052513A1
公开(公告)日：2015-02-19
申请号：US14458807
申请日：2014-08-13
申请人： Marck R. Robinson
发明人： Marck R. Robinson
IPC分类号： G06F9/445 , H04L29/06 , G06F17/30 , H04L12/26 , H04L29/08 , H04L12/24
CPC分类号： G06F8/65 , G06F8/61 , G06F17/30899 , H04L41/22 , H04L43/00 , H04L51/04 , H04L67/02 , H04L67/2804 , H04L67/42
摘要： Techniques for live data management are described. Some embodiments provide a Live Data Management System (“LDMS”) that provides a facility for managing live data objects and for efficiently developing client-server applications that utilize such live data objects. Live data objects are modules of computation that exist on both a client side and server side portion of a client-server application. Live data objects are configured to monitor changes to data hosted on or accessible via the server side, and to automatically update the client side without the need for polling or other requests made by the client side. The described techniques facilitate efficient software development of Web-based client server applications.
摘要翻译：描述了实时数据管理技术。一些实施例提供了一种实时数据管理系统（“LDMS”），其提供用于管理实时数据对象的设施，并且有效开发利用这种实时数据对象的客户端 - 服务器应用程序。实时数据对象是存在于客户机 - 服务器应用程序的客户端和服务器端部分的计算模块。实时数据对象被配置为监视托管在服务器端或可通过服务器端访问的数据的更改，并自动更新客户端，而不需要由客户端进行轮询或其他请求。所描述的技术有助于基于Web的客户端服务器应用程序的高效软件开发。

6. 发明申请

US20140302007A1 BOTULINUM TOXIN FORMULATION 审中-公开
标题翻译：丁香毒素配方
公开(公告)号：US20140302007A1
公开(公告)日：2014-10-09
申请号：US13466806
申请日：2012-05-08
申请人： Wendy M. Blanda , Rober K. Aoki , Terrence J. Hunt , Patrick M. Hughes , James N. Chang , Scott M. Whitcup , Michael R. Robinson
发明人： Wendy M. Blanda , Rober K. Aoki , Terrence J. Hunt , Patrick M. Hughes , James N. Chang , Scott M. Whitcup , Michael R. Robinson
IPC分类号： A61K38/48 , A61K9/00 , A61K47/36
CPC分类号： A61K38/4893 , A61K9/0019 , A61K9/0024 , A61K47/36 , C12Y304/24069
摘要： Botulinum neurotoxin formulated with a hyaluronic acid carrier with increased residency time of the botulinum toxin at a subdermal location and fewer botulinum toxin induced complications or side effects.
摘要翻译：用透明质酸载体配制的肉毒杆菌神经毒素，肉毒杆菌毒素在皮下位置的驻留时间增加，肉毒杆菌毒素诱导的并发症或副作用较少。

7. 发明授权

US08831024B2 Dynamic header creation and flow control for a programmable communications processor, and applications thereof 有权
标题翻译：用于可编程通信处理器的动态报头创建和流量控制及其应用
公开(公告)号：US08831024B2
公开(公告)日：2014-09-09
申请号：US11966843
申请日：2007-12-28
申请人： Michael R. Robinson , Joel I. Danzig , Thomas L. Johnson
发明人： Michael R. Robinson , Joel I. Danzig , Thomas L. Johnson
IPC分类号： H04L12/28 , H04L12/56
CPC分类号： H04L47/36 , H04L12/2801 , H04L47/10 , H04L47/21 , H04L47/29 , H04L49/90 , H04L49/901 , H04L49/9042 , H04L69/22
摘要： A method, system and computer program product for creating dynamic custom headers and for controlling flow rate of Downstream External Physical layer Interface (DEPI) packets are described herein. The method comprises concatenating or fragmenting a packet descriptor of a DEPU packet based on one or more of associated packet size, maximum transmission unit, packet type, channel configuration information and flow control mode. The method further comprises creating a header for the packet based on data in a programmable header template and storing the header in a header buffer, determining whether to transmit the packet based on one of a flow meter or a maximum transmission unit size and transmitting the packet by sending the packet descriptor to an output direct memory access (DMA) controller. A flow meter flow control mode determines if a packet is to be transmitted based on packet size, bucket size, a low threshold and a high threshold. A maximum transmission unit flow control mode determines if a packet is to transmitted based on packet size and a maximum transmission unit size. The header can be customized for Packet Streaming Protocol (PSP) mode or Moving Picture Experts Group Transport Stream (MPT) mode and includes dynamic customizable fields such as User Datagram Protocol (UDP) port identification, flow identification and session identification.
摘要翻译：本文描述了用于创建动态定制头部和用于控制下游外部物理层接口（DEPI）分组的流量的方法，系统和计算机程序产品。该方法包括基于相关联的分组大小，最大传输单元，分组类型，信道配置信息和流控制模式中的一个或多个来连接或分段DEPU分组的分组描述符。该方法还包括基于可编程头部模板中的数据创建分组头部，并将头部存储在头部缓冲器中，基于流量计或最大传输单元大小之一确定是否发送分组，并发送分组通过将分组描述符发送到输出直接存储器访问（DMA）控制器。流量计流量控制模式基于分组大小，桶大小，低阈值和高阈值来确定是否要发送分组。最大传输单元流量控制模式基于分组大小和最大传输单元大小确定是否要发送分组。可以为分组流协议（PSP）模式或运动图像专家组传输流（MPT）模式定制报头，并且包括诸如用户数据报协议（UDP）端口标识，流识别和会话识别之类的动态可定制字段。

8. 发明授权

US08753611B2 Sublingual buccal effervescent 有权
公开(公告)号：US08753611B2
公开(公告)日：2014-06-17
申请号：US13099003
申请日：2011-05-02
申请人： Jonathan D. Eichman , John Hontz , Rajendra K. Khankari , Sathasivan Indiran Pather , Joseph R. Robinson
发明人： Jonathan D. Eichman , John Hontz , Rajendra K. Khankari , Sathasivan Indiran Pather , Joseph R. Robinson
IPC分类号： A01N25/02 , A61K9/12 , A61F13/00 , A61K9/20 , A61K9/46
CPC分类号： A61K31/4468 , A61K9/0007 , A61K9/0056 , A61K9/006 , A61K31/5415
摘要： A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional pH adjusting substance in combination with the effervescent for promoting the absorption drugs is also disclosed.

9. 发明申请

US20140099364A2 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER 审中-公开
公开(公告)号：US20140099364A2
公开(公告)日：2014-04-10
申请号：US11576871
申请日：2005-10-07
申请人： Henrik NILSSON , Florian SCHOENHARTING , Bernd W. MUELLER , Joseph R. ROBINSON
发明人： Henrik NILSSON , Florian SCHOENHARTING , Bernd W. MUELLER , Joseph R. ROBINSON
IPC分类号： A61K9/20 , A61K31/225 , A61P3/10 , A61K31/22
CPC分类号： A61K31/225 , A61K9/0053 , A61K9/14 , A61K9/167 , A61K9/20 , A61K9/2013 , A61K9/2027 , A61K9/2031 , A61K9/2054 , A61K9/2077 , A61K9/2081 , A61K9/28 , A61K9/2846 , A61K9/48 , A61K9/4808 , A61K9/4891 , A61K9/50 , A61K9/5042 , A61K9/5047 , A61K9/5084 , A61K31/215 , A61K31/22 , A61K45/06 , A61K2300/00
摘要： The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.

10. 发明授权

US08617640B2 Thin-film devices formed from solid group IIIA alloy particles 失效
标题翻译：由固体IIIA族合金颗粒形成的薄膜器件
公开(公告)号：US08617640B2
公开(公告)日：2013-12-31
申请号：US11762056
申请日：2007-06-12
申请人： Matthew R. Robinson , Chris Eberspacher , Jeroen K. J. Van Duren
发明人： Matthew R. Robinson , Chris Eberspacher , Jeroen K. J. Van Duren
IPC分类号： B05D5/06
CPC分类号： H01L31/0322 , Y02E10/541
摘要： Methods and devices are provided for forming thin-films from solid group IIIA-based particles. In one embodiment, a method is provided for creating solid alloy particles. The method may include providing a first material containing at least one alloy comprising of: a) a group IIIA element, b) at least one group IB, IIIA, and/or VIA element different from the group IIIA element of a), and c) a group IA-based material. The group IA-based material may be included in an amount sufficient so that no liquid phase of the alloy is present in a temperature range between room temperature and a deposition temperature higher than room temperature, wherein the group IIIA element is otherwise liquid in that temperature range. The method may involve formulating a precursor material comprising of: a) particles of the first material and b) particles containing at least one element from one of the following: a group IB element, a group IIIA element, a group VIA element, alloys containing any of the foregoing elements, or combinations thereof.
摘要翻译：提供了用于从基于固体IIIA的颗粒形成薄膜的方法和装置。在一个实施例中，提供了一种用于产生固体合金颗粒的方法。该方法可以包括提供包含至少一种合金的第一材料，其包含：a）IIIA族元素，b）至少一种不同于a）的IIIA族元素的IB，IIIA和/或VIA元素，c ）一组基于IA的材料。基于IA族的材料可以包括足够的量，使得在室温和高于室温的沉积温度之间的温度范围内不存在合金的液相，其中IIIA族元素在该温度下为液体范围。该方法可以包括配制前体材料，其包括：a）第一材料的颗粒，和b）含有至少一种元素的颗粒，如下列之一：IB族元素，IIIA族元素，VIA族元素，含任何上述要素，或其组合。

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