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    • 2. 发明申请
    • GLYCOLIPIDS OF BRANCHED CHAIN ALKYL OLIGOSACCHARIDES FOR LIQUID CRYSTAL AND RELATED APPLICATIONS
    • 用于液晶的分支链烷基低聚物的甘氨酸和相关应用
    • US20130150567A1
    • 2013-06-13
    • US13668632
    • 2012-11-05
    • RAUZAH HASHIMThorsten HEIDELBERGHind HASSANNasrul Zamani MOHD RODZIRusnah Syahila DAULI HUSSENAhmad Sazali HAMZAHShahidan RADIMANVolkmar VILLMatthias WULFSeiji UJIIE
    • RAUZAH HASHIMThorsten HEIDELBERGHind HASSANNasrul Zamani MOHD RODZIRusnah Syahila DAULI HUSSENAhmad Sazali HAMZAHShahidan RADIMANVolkmar VILLMatthias WULFSeiji UJIIE
    • C07H15/04
    • C07H15/04C09K19/0422
    • Glycolipids of branched chain alkyl oligosaccharides according to this patent comprise of a primary alcohol branched in the 2-position and an oligosaccharide, covalently bond to the alcohol in either α- or β-linkage (shown in Formula I and Formula II). These compounds show particularly interesting phase behavior not found for the corresponding straight chain counterparts. The properties involve an ambient temperature liquid crystalline appearance and thermotropic liquid crystal phase polymorphism. Upon the latter, the formation of cubic phases is considered most interesting with respect to life science applications, e.g. liposome for drug delivery. Depending on the choice of sugar head group and alkyl tail, various levels of water miscibility may be adjusted to meet applications requirements (complete solubility for emulsifier applications, e.g. cosmetic creams, to limited water swelling only, e.g. for the preparation of artificial membranes). The closed structural relationship to natural lipids also make branched chain alkyl oligosaccharides valuable subjects for biochemical investigations, e.g. membrane studies. The range of possible applications for glycolipids of branched chain alkyl oligosaccharides involve material science liquid crystal applications, e.g. optical switches, as well as surfactants and the life science applications (see above).
    • 根据该专利的支链烷基寡糖的糖脂包含在2-位上分支的伯醇和寡糖,以α-或β-键(式I和式II所示)共价键合到醇上。 这些化合物表现出对于相应的直链对应物没有发现的特别有趣的相行为。 性质包括环境温度液晶外观和热致液晶相多态性。 在后者中,立方相的形成在生命科学应用方面被认为是最有趣的。 用于药物递送的脂质体。 根据糖头基和烷基尾的选择,可以调节不同水平的水混溶性以满足应用要求(对于乳化剂应用(例如化妆品乳液,仅限于有限的水溶胀,例如制备人造膜)的完全溶解度)。 与天然脂质的封闭结构关系也使支链烷基寡糖成为生物化学研究的有价值的对象,例如。 膜研究。 支链烷基寡糖的糖脂的可能应用的范围涉及材料科学液晶应用,例如 光学开关,以及表面活性剂和生命科学应用(见上文)。
    • 3. 发明授权
    • Glycolipids of branched chain alkyl oligosaccharides for liquid crystal and related applications
    • 用于液晶的支链烷基寡糖的糖脂及相关应用
    • US08304525B2
    • 2012-11-06
    • US11908791
    • 2006-02-20
    • Rauzah HashimThorsten HeidelbergHind HassanNasrul Zamani Mohd RodziRusnah Syahila Dauli HussenAhmad Sazali HamzahShahidan RadimanVolkmar VillMatthias WulfSeiji Ujiie
    • Rauzah HashimThorsten HeidelbergHind HassanNasrul Zamani Mohd RodziRusnah Syahila Dauli HussenAhmad Sazali HamzahShahidan RadimanVolkmar VillMatthias WulfSeiji Ujiie
    • C07H17/02C07H15/08
    • C07H15/04C09K19/0422
    • Glycolipids of branched chain alkyl oligosaccharides according to this patent comprise of a primary alcohol branched in the 2-position and an oligosaccharide, covalently bond to the alcohol in either α- or β-linkage (shown in Formula I and Formula II). These compounds show particularly interesting phase behavior not found for the corresponding straight chain counterparts. The properties involve an ambient temperature liquid crystalline appearance and thermotropic liquid crystal phase polymorphism. Upon the latter, the formation of cubic phases is considered most interesting with respect to life science applications, e.g. liposome for drug delivery. Depending on the choice of sugar head group and alkyl tail, various levels of water miscibility may be adjusted to meet applications requirements (complete solubility for emulsifier applications, e.g. cosmetic creams, to limited water swelling only, e.g. for the preparation of artificial membranes). The closed structural relationship to natural lipids also make branched chain alkyl oligosaccharides valuable subjects for biochemical investigations, e.g. membrane studies. The range of possible applications for glycolipids of branched chain alkyl oligosaccharides involve material science liquid crystal applications, e.g, optical switches, as well as surfactants and the life science applications.
    • 根据该专利的支链烷基寡糖的糖脂包含在2-位上分支的伯醇和低聚糖,以α-或β-连接(式I和式II所示)与醇共价键合。 这些化合物表现出对于相应的直链对应物没有发现的特别有趣的相行为。 性质包括环境温度液晶外观和热致液晶相多态性。 在后者中,立方相的形成在生命科学应用方面被认为是最有趣的。 用于药物递送的脂质体。 根据糖头基和烷基尾的选择,可以调节不同水平的水混溶性以满足应用要求(对于乳化剂应用(例如化妆品乳液,仅限于有限的水溶胀,例如制备人造膜)的完全溶解度)。 与天然脂质的封闭结构关系也使支链烷基寡糖成为生物化学研究的有价值的对象,例如。 膜研究。 支链烷基寡糖的糖脂的可能应用范围涉及材料科学液晶应用,例如光学开关,以及表面活性剂和生命科学应用。
    • 4. 发明申请
    • GLYCOLIPIDS OF BRANCHED CHAIN ALKYL OLIGOSACCHARIDES FOR LIQUID CRYSTAL AND RELATED APPLICATIONS
    • 用于液晶的分支链烷基低聚物的甘氨酸和相关应用
    • US20090036669A1
    • 2009-02-05
    • US11908791
    • 2006-02-20
    • Rauzah HashimThorsten HeidelbergHind HassanNasrul Zamani Mohd RodziRusnah Syahila Dauli HussenAhmad Sazali HamzahShahidan RadimanVolkmar ViliMatthias WulfSeiji Ujiie
    • Rauzah HashimThorsten HeidelbergHind HassanNasrul Zamani Mohd RodziRusnah Syahila Dauli HussenAhmad Sazali HamzahShahidan RadimanVolkmar ViliMatthias WulfSeiji Ujiie
    • C13K7/00
    • C07H15/04C09K19/0422
    • Glycolipids of branched chain alkyl oligosaccharides according to this patent comprise of a primary alcohol branched in the 2-position and an oligosaccharide, covalently bond to the alcohol in either α- or β-linkage (shown in Formula I and Formula II). These compounds show particularly interesting phase behavior not found for the corresponding straight chain counterparts. The properties involve an ambient temperature liquid crystalline appearance and thermotropic liquid crystal phase polymorphism. Upon the latter, the formation of cubic phases is considered most interesting with respect to life science applications, e.g. liposome for drug delivery. Depending on the choice of sugar head group and alkyl tail, various levels of water miscibility may be adjusted to meet applications requirements (complete solubility for emulsifier applications, e.g. cosmetic creams, to limited water swelling only, e.g. for the preparation of artificial membranes). The closed structural relationship to natural lipids also make branched chain alkyl oligosaccharides valuable subjects for biochemical investigations, e.g. membrane studies. The range of possible applications for glycolipids of branched chain alkyl oligosaccharides involve material science liquid crystal applications, e.g, optical switches, as well as surfactants and the life science applications.
    • 根据该专利的支链烷基寡糖的糖脂包含在2-位上分支的伯醇和寡糖,以α-或β-键(式I和式II所示)共价键合到醇上。 这些化合物表现出对于相应的直链对应物没有发现的特别有趣的相行为。 性质包括环境温度液晶外观和热致液晶相多态性。 在后者中,立方相的形成在生命科学应用方面被认为是最有趣的。 用于药物递送的脂质体。 根据糖头基和烷基尾的选择,可以调节不同水平的水混溶性以满足应用要求(对于乳化剂应用(例如化妆品乳液,仅限于有限的水溶胀,例如制备人造膜)的完全溶解度)。 与天然脂质的封闭结构关系也使支链烷基寡糖成为生物化学研究的有价值的对象,例如。 膜研究。 支链烷基寡糖的糖脂的可能应用范围涉及材料科学液晶应用,例如光学开关,以及表面活性剂和生命科学应用。