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1. 发明授权

US5279738A Permeable membrane excellent in biocompatibility 失效
标题翻译：渗透膜生物相容性优异
公开(公告)号：US5279738A
公开(公告)日：1994-01-18
申请号：US881636
申请日：1992-05-12
申请人： Yukio Seita , Hideaki Kito , Katsuhiro Takanashi , Mitsuhide Nakagawa
发明人： Yukio Seita , Hideaki Kito , Katsuhiro Takanashi , Mitsuhide Nakagawa
IPC分类号： B01D67/00 , B01D71/56 , B01D71/80 , C08G69/40 , C08G69/48
CPC分类号： B01D67/0088 , B01D71/56 , B01D71/80 , C08G69/40 , C08G69/48
摘要： A permeable membrane excellent in biocompatibility, produced by forming coagulation by melting method in the form of a membrane a terminal-modified polyamide, i.e. a polyether amide comprising component units represented by the following structural formula (I), (II), (III), or (IV), possessing hydrocarbon groups of one to 22 carbon atoms at the terminals thereof, and having a molecular weight in the range of from 10,000 to 100,000, said terminal-modified polyamide being such that the number of said hydrocarbon groups is in the range of from 5 to 100% based on the number of all of the terminal groups of said polyether amide, placing said membrane in contact with a medium capable of swelling or partially dissolving said membrane, and further placing the resultant altered membrane in contact with a solution consisting mainly of a nonsolvent for said polyether amide. ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are independently a linear or branched alkylene group of two to four carbon atoms, R.sup.4,R.sup.5, and R.sup.6 are independently an aliphatic, alicyclic, or aromatic hydrocarbon group of two to 36 carbon atoms, n is a numeral in the range of from 0 to 180, and m is a numeral in the range of from 1 to 400.
摘要翻译：一种生物相容性优异的渗透膜，其通过以膜结构形式凝固形成末端改性聚酰胺，即包含由以下结构式（I），（II），（III）所示的组分单元的聚醚酰胺）或（IV），其末端具有1至22个碳原子的烃基，并且分子量在10,000至100,000的范围内，所述末端改性聚酰胺使得所述烃基的数目为基于所述聚醚酰胺的所有末端基团的数目为5至100％的范围，将所述膜与能够溶胀或部分溶解所述膜的介质接触，并进一步将所得改变的膜与主要由所述聚醚酰胺的非溶剂组成的溶液。（*化学结构*）（I）（*化学结构*）（II）（*化学结构*）（III）（*化学结构*）（Ⅳ）其中R1，R2和R3独立地为直链或支链亚烷基 2-4个碳原子的基团，R4，R5和R6独立地是2至36个碳原子的脂族，脂环族或芳族烃基，n是0至180的数字，m是数字在1到400的范围内。

2. 发明授权

US5137635A Permeable membrane excellent in biocompatibility 失效
标题翻译：可渗透膜优于生物化学
公开(公告)号：US5137635A
公开(公告)日：1992-08-11
申请号：US721682
申请日：1991-06-26
申请人： Yukio Seita , Hideaki Kito , Katsuhiro Takanashi , Mitsuhide Nakagawa
发明人： Yukio Seita , Hideaki Kito , Katsuhiro Takanashi , Mitsuhide Nakagawa
IPC分类号： B01D67/00 , B01D71/56 , B01D71/80 , C08G69/40 , C08G69/48
CPC分类号： B01D67/0088 , B01D71/56 , B01D71/80 , C08G69/40 , C08G69/48
摘要： A permeable membrane excellent in biocompatibility, produced by forming coagulation by melting method in the form of a membrane a terminal-modified polyamide, i.e. a polyether amide comprising component units represented by the following structural formula (I), (II), (III), or (IV), possessing hydrocarbon groups of one to 22 carbon atoms at the terminals thereof, and having a molecular weight in the range of from 10,000 to 100,000, said terminal-modified polyamide being such that the number of said hydrocarbon groups is in the range of from 5 to 100% based on the number of all of the terminal groups of said polyester amide, placing said membrane in contact with a medium capable of swelling or partially dissolving said membrane, and further placing the resultant altered membrane in contact with a solution consisting mainly of a nonsolvent for said polyether amide. ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are independently a linear or branched alkylene group of two to four carbon atoms, R.sup.4, R.sup.5, and R.sup.6 are independently an aliphatic, alicyclic, or aromatic hydrocarbon group of two to 36 carbon atoms, n is a numeral in the range of from 0 to 180, and m is a numeral in the range of from 1 to 400.

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