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1. 发明授权

US08685264B2 Slide member and method for the production thereof 有权
标题翻译：滑动构件及其制造方法
公开(公告)号：US08685264B2
公开(公告)日：2014-04-01
申请号：US13822138
申请日：2011-09-12
申请人： Masataka Kaido , Atsushi Suzuki , Masatsugu Shimomura , Hiroshi Yabu , Yuji Hirai
发明人： Masataka Kaido , Atsushi Suzuki , Masatsugu Shimomura , Hiroshi Yabu , Yuji Hirai
IPC分类号： B44C1/22 , C03C15/00 , C03C25/68 , C23F1/00
CPC分类号： F16C33/02 , F16C33/103 , F16C33/14 , F16C2220/60 , F16C2240/40 , F16C2240/44
摘要： A slide member includes a substrate that is made of a metal material and has a sliding surface with a plurality of microdimples formed therein. Each of the microdimple has a circular opening, the microdimples are arranged in regular intervals in a hexagonal close-packed configuration, and the area ratio of the openings of all the microdimples to the entire sliding surface is in the range of 50 to 80%.
摘要翻译：滑动构件包括由金属材料制成并且具有形成有多个微型微粒的滑动面的基板。每个微型微型物具有圆形开口，微型粉末以六边形紧密构造的规则间隔布置，并且所有微小的微孔的开口面积与整个滑动面的面积比在50％至80％的范围内。

2. 发明申请

US20130168351A1 SLIDE MEMBER AND METHOD FOR THE PRODUCTION THEREOF 有权
标题翻译：滑动构件及其制造方法
公开(公告)号：US20130168351A1
公开(公告)日：2013-07-04
申请号：US13822138
申请日：2011-09-12
申请人： Masataka Kaido , Atsushi Suzuki , Masatsugu Shimomura , Hiroshi Yabu , Yuji Hirai
发明人： Masataka Kaido , Atsushi Suzuki , Masatsugu Shimomura , Hiroshi Yabu , Yuji Hirai
IPC分类号： F16C33/02
CPC分类号： F16C33/02 , F16C33/103 , F16C33/14 , F16C2220/60 , F16C2240/40 , F16C2240/44
摘要： A slide member includes a substrate that is made of a metal material and has a sliding surface with a plurality of microdimples formed therein. Each of the microdimple has a circular opening, the microdimples are arranged in regular intervals in a hexagonal close-packed configuration, and the area ratio of the openings of all the microdimples to the entire sliding surface is in the range of 50 to 80%.
摘要翻译：滑动构件包括由金属材料制成并且具有形成有多个微型微粒的滑动面的基板。每个微型微型物具有圆形开口，微型粉末以六边形紧密构造的规则间隔布置，并且所有微小的微孔的开口面积与整个滑动面的面积比在50％至80％的范围内。

3. 发明申请

US20100035766A1 CELL CHIP 审中-公开
标题翻译：电池芯片
公开(公告)号：US20100035766A1
公开(公告)日：2010-02-11
申请号：US12302705
申请日：2007-05-30
申请人： Masaru Tanaka , Shusaku Tsukiyama , Sadaaki Yamamoto , Masatsugu Shimomura , Hidekazu Yamazaki , Hideaki Naruse
发明人： Masaru Tanaka , Shusaku Tsukiyama , Sadaaki Yamamoto , Masatsugu Shimomura , Hidekazu Yamazaki , Hideaki Naruse
IPC分类号： C40B30/06 , C40B40/02
CPC分类号： G01N33/5067 , C12N9/96 , C12Q1/02 , G01N33/54366
摘要： Disclosed is a novel cell chip having a living cell retained on a substrate while keeping the functions of the cell. Specifically, disclosed is a cell chip which comprises a honeycomb-like porous material having through-pores therein and composed of a water-insoluble polymer and a human hepatocyte retained on the porous material. The cell chip, particularly one having a human hepatocyte retained on both surfaces of the honeycomb-like porous material, is advantageous, because it can keep the activity of a drug-metabolizing enzyme (particularly, a P450 activity) for a long period, can keep the number of the cells stably, and so on.
摘要翻译：公开了一种新颖的细胞芯片，其具有在保持细胞功能的同时保留在基板上的活细胞。具体地，公开了一种细胞芯片，其包括其中具有通孔的蜂窝状多孔材料，其由保持在多孔材料上的水不溶性聚合物和人肝细胞组成。特别是在蜂窝状多孔质体的两面保留有人肝细胞的细胞芯片是有利的，因为它可以长时间保持药物代谢酶（特别是P450活性）的活性，可以保持细胞的数量稳定，等等。

4. 发明授权

US07531211B2 Process for production of submicrohoneycomb structures 失效
标题翻译：亚微米结构的生产工艺
公开(公告)号：US07531211B2
公开(公告)日：2009-05-12
申请号：US11661620
申请日：2007-05-03
申请人： Masatsugu Shimomura , Hiroshi Yabu
发明人： Masatsugu Shimomura , Hiroshi Yabu
IPC分类号： B05D3/04
CPC分类号： B29C41/28 , B29C41/12 , B29C47/0028 , B29D24/005 , B29D99/0089 , B29L2031/60 , B29L2031/756 , C08J9/28 , C08J2201/0502
摘要： A process for the production of a honeycomb-like porous body of 10 to 1000 nm in thickness which is made of a water-insoluble polymer and has pores having diameters of 10 to 100 nm, which comprises the following steps: (1) the step of dissolving a water-insoluble polymer in a water-incompatible organic solvent having a surface tension (γL) of 50 dyne/cm or below to prepare a solution of the polymer in the organic solvent, (2) the step of applying the solution prepared in the step (1) to the surface of a substrate with the proviso that the surface tension (γS) of the substrate, the surface tension (γL) of the organic solvent, and the surface tension (γSL) between the substrate and the solvent satisfy the relationship: γS−γSL>γL, and (3) the step of bringing the solution applied on the substrate into contact with air having a relative humidity of 30% or above to evaporate the organic solvent at such a rate that the coating thickness at applying the solution to the surface of the substrate is reduced to one-fifth within one second.
摘要翻译：一种制造厚度为10〜1000nm的蜂窝状多孔体的方法，该蜂窝状多孔体由水不溶性聚合物制成，具有直径为10〜100nm的孔，其包括以下步骤：（1）步骤将水不溶性聚合物溶解在表面张力（γL）为50达因/厘米或更低的水不相容的有机溶剂中以制备聚合物在有机溶剂中的溶液，（2）将制备的溶液在步骤（1）中到基底的表面，条件是基材的表面张力（γS），有机溶剂的表面张力（γL）和基材和溶剂之间的表面张力（γSL）满足γS-γSL>γL的关系，（3）将施加在基板上的溶液与相对湿度为30％以上的空气接触的步骤，以使涂布厚度在应用解决方案衬底的表面在一秒钟内减少到五分之一。

5. 发明申请

US20080032048A1 Process For Production Of Submicrohoneycomb Structures 失效
标题翻译：亚微米结构的生产工艺
公开(公告)号：US20080032048A1
公开(公告)日：2008-02-07
申请号：US11661620
申请日：2005-08-25
申请人： Masatsugu Shimomura , Hiroshi Yabu
发明人： Masatsugu Shimomura , Hiroshi Yabu
IPC分类号： C08J9/28 , B29C41/12 , B29C41/24 , C08L101/00 , B29L7/00 , B82B3/00
CPC分类号： B29C41/28 , B29C41/12 , B29C48/11 , B29D24/005 , B29D99/0089 , B29L2031/60 , B29L2031/756 , C08J9/28 , C08J2201/0502
摘要： A process for the production of a honeycomb-like porous body of 10 to 1000 nm in thickness which is made of a water-insoluble polymer and has pores having diameters of 10 to 100 nm, which comprises the following steps: (1) the step of dissolving a water-insoluble polymer in a water-incompatible organic solvent having a surface tension (γL) of 50 dyne/cm or below to prepare a solution of the polymer in the organic solvent, (2) the step of applying the solution prepared in the step (1) to the surface of a substrate with the proviso that the surface tension (γS) of the substrate, the surface tension (γL) of the organic solvent, and the surface tension (γSL) between the substrate and the solvent satisfy the relationship: γS−γSL>γL, and (3) the step of bringing the solution applied on the substrate into contact with air having a relative humidity of 30% or above to evaporate the organic solvent at such a rate that the coating thickness at applying the solution to the surface of the substrate is reduced to one-fifth within one second.
摘要翻译：一种制造厚度为10〜1000nm的蜂窝状多孔体的方法，该蜂窝状多孔体由水不溶性聚合物制成，具有直径为10〜100nm的孔，其包括以下步骤：（1）步骤将水不溶性聚合物溶解在表面张力（γL）为50达因/厘米或更低的水不相容的有机溶剂中以制备聚合物在有机溶剂中的溶液，（2）将制备的溶液在步骤（1）中到基底的表面，条件是基材的表面张力（γS），有机溶剂的表面张力（γL）和基材和溶剂之间的表面张力（γSL）满足γS-γSL>γL的关系，（3）将施加在基板上的溶液与相对湿度为30％以上的空气接触的步骤，以使涂布厚度在应用解决方案衬底的表面在一秒钟内减少到五分之一。

6. 发明授权

US08097273B2 Biodegradable film having honeycomb structure 有权
标题翻译：具有蜂窝结构的生物降解膜
公开(公告)号：US08097273B2
公开(公告)日：2012-01-17
申请号：US10552685
申请日：2004-04-08
申请人： Yukako Fukuhira , Eiichi Kitazono , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
发明人： Yukako Fukuhira , Eiichi Kitazono , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
IPC分类号： A61F13/00 , A61F2/00
CPC分类号： B29C41/12 , A61L31/06 , A61L31/14 , C08L67/04
摘要： The invention relates to a honeycomb film made of a biodegradable polymer which has biodegradation properties as an anti-adhesion membrane for preventing adhesion after an operation, is excellent in handling properties, and exhibits a satisfactory adhesion preventive effect stably over a desired period of time, and to a production process of the same. Above all, the invention provides an anti-adhesion membrane of a honeycomb film made of polylactic acid as a biodegradable polymer and a phospholipid and a production process of the same.
摘要翻译：本发明涉及一种由生物降解性聚合物制成的蜂窝膜，其具有生物降解性，作为防止粘合后的防粘膜，操作性优异，并且在期望的时间段内稳定地表现出令人满意的粘合防止效果，以及其生产过程。其中，本发明提供了由聚乳酸作为生物降解性聚合物和磷脂制成的蜂窝膜的防粘膜及其制造方法。

7. 发明授权

US07915028B2 Tissue regeneration substrate, complex thereof with cells, and method for its production 有权
标题翻译：组织再生底物，与细胞的复合物及其制备方法
公开(公告)号：US07915028B2
公开(公告)日：2011-03-29
申请号：US10580029
申请日：2004-11-19
申请人： Yukako Fukuhira , Masaya Ito , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
发明人： Yukako Fukuhira , Masaya Ito , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
IPC分类号： C12M3/00 , A01N1/02
CPC分类号： A61L27/3817 , A61L27/3852 , A61L27/446 , A61L27/50 , A61L27/56 , A61L2430/06
摘要： A tissue regeneration substrate comprising a film with a honeycomb structure composed primarily of a polymer compound and a phospholipid. A tissue regeneration complex comprising the tissue regeneration substrate and cells held in the tissue regeneration substrate. The substrate is particularly suitable for regeneration of cartilage tissue, and allows growth of cartilage tissue in a three-dimensional fashion.
摘要翻译：一种组织再生基材，其包含主要由高分子化合物和磷脂构成的蜂窝结构体的膜。一种组织再生复合体，其包含组织再生基质和保持在组织再生基质中的细胞。该底物特别适用于软骨组织的再生，并允许以三维方式生长软骨组织。

8. 发明申请

US20070212521A1 Anisotropic Conductive Film and a Method of Manufacturing the Same 审中-公开
标题翻译：各向异性导电膜及其制造方法
公开(公告)号：US20070212521A1
公开(公告)日：2007-09-13
申请号：US10593622
申请日：2005-03-29
申请人： Hisami Bessho , Hideyuki Sato , Akio Sato , Masatsugu Shimomura , Masaru Tanaka , Hiroshi Yabu
发明人： Hisami Bessho , Hideyuki Sato , Akio Sato , Masatsugu Shimomura , Masaru Tanaka , Hiroshi Yabu
IPC分类号： B32B3/10
CPC分类号： H01R12/7076 , C09J7/22 , C09J7/26 , C09J2201/128 , C09J2201/602 , H01R13/2414 , H05K3/323 , H05K2201/0116 , H05K2201/09945 , H05K2201/10378 , Y10T428/24322
摘要： To provide an anisotropic conductive film which can respond to increasing pitch reduction of connection targets while maintaining connection reliability, and can be manufactured at a lower cost than conventional, and to provide a method of manufacturing the same. The anisotropic conductive film is provided with a porous film consisting of polymer, having numerous holes penetrating in a film thickness direction, the holes being in a honeycomb arrangement and having inner wall surfaces which curve outwards, a conductive material that fills the holes in the porous film, and an adhesive layer coated on both surfaces of the porous film. The porous film is formed by leaving a supporting substrate on which cast is a polymer solution where a polymer is dissolved in a hydrophobic, volatile organic solvent, under high humidity conditions.
摘要翻译：为了提供能够对维持连接可靠性的连接目标的减小的增加作出响应的各向异性导电膜，并且可以以比传统的更低的成本制造并提供其制造方法。各向异性导电膜设置有由聚合物组成的多孔膜，其具有沿膜厚度方向穿透的多个孔，该孔为蜂窝结构，并且具有向外弯曲的内壁表面，填充多孔的孔的导电材料膜和涂覆在多孔膜的两个表面上的粘合剂层。多孔膜通过在高湿度条件下留下支撑基底而形成，其上浇注聚合物溶液，其中聚合物溶解在疏水性挥发性有机溶剂中。

9. 发明申请

US20070112438A1 Tissue regeneration substrate, complex thereof with cells, and method for its production 有权
标题翻译：组织再生底物，与细胞的复合物及其制备方法
公开(公告)号：US20070112438A1
公开(公告)日：2007-05-17
申请号：US10580029
申请日：2004-11-19
申请人： Yukako Fukuhira , Masaya Ito , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
发明人： Yukako Fukuhira , Masaya Ito , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
IPC分类号： A61F2/02
CPC分类号： A61L27/3817 , A61L27/3852 , A61L27/446 , A61L27/50 , A61L27/56 , A61L2430/06
摘要： A tissue regeneration substrate comprising a film with a honeycomb structure composed primarily of a polymer compound and a phospholipid. A tissue regeneration complex comprising the tissue regeneration substrate and cells held in the tissue regeneration substrate. The substrate is particularly suitable for regeneration of cartilage tissue, and allows growth of cartilage tissue in a three-dimensional fashion.
摘要翻译：一种组织再生基材，其包含主要由高分子化合物和磷脂构成的蜂窝结构体的膜。一种组织再生复合体，其包含组织再生基质和保持在组织再生基质中的细胞。该底物特别适用于软骨组织的再生，并允许以三维方式生长软骨组织。

10. 发明申请

US20060189911A1 Biodegradable film having honeycomb structure 有权
标题翻译：具有蜂窝结构的生物降解膜
公开(公告)号：US20060189911A1
公开(公告)日：2006-08-24
申请号：US10552685
申请日：2004-04-08
申请人： Yukako Fukuhira , Eiichi Kitazono , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
发明人： Yukako Fukuhira , Eiichi Kitazono , Hiroaki Kaneko , Yoshihiko Sumi , Masatsugu Shimomura , Masaru Tanaka
IPC分类号： A61F13/00 , A61F15/00
CPC分类号： B29C41/12 , A61L31/06 , A61L31/14 , C08L67/04
摘要： The invention relates to a honeycomb film made of a biodegradable polymer which has biodegradation properties as an anti-adhesion membrane for preventing adhesion after an operation, is excellent in handling properties, and exhibits a satisfactory adhesion preventive effect stably over a desired period of time, and to a production process of the same. Above all, the invention provides an anti-adhesion membrane of a honeycomb film made of polylactic acid as a biodegradable polymer and a phospholipid and a production process of the same.
摘要翻译：本发明涉及一种由生物降解性聚合物制成的蜂窝膜，其具有生物降解性，作为防止粘合后的防粘膜，操作性优异，并且在期望的时间段内稳定地表现出令人满意的粘合防止效果，以及其生产过程。其中，本发明提供了由聚乳酸作为生物降解性聚合物和磷脂制成的蜂窝膜的防粘膜及其制造方法。

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