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1. 发明授权

US06436420B1 High performance silver (I,III) oxide antimicrobial textile articles 失效
标题翻译：高性能银（I，III）氧化物抗菌纺织制品
公开(公告)号：US06436420B1
公开(公告)日：2002-08-20
申请号：US09477883
申请日：2000-01-05
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A01N2534
CPC分类号： A61F13/84 , A01N59/16 , A61F13/00063 , A61F2013/00936 , A61F2013/8414 , A61F2013/8426 , D06M11/38 , D06M11/83 , D06M16/00 , A01N25/34 , A01N2300/00
摘要： Fibrous textile articles possessing enhanced antimicrobial properties are prepared by the deposition or interstitial precipitation of tetrasilver tetroxide (Ag4O4) crystals within the interstices of fibers, yarns and/or fabrics forming such articles.
摘要翻译：具有增强的抗微生物性能的纤维织物通过在形成这种制品的纤维，纱线和/或织物的间隙内四氧化四砷（Ag 4 O 4）晶体的沉积或间隙沉淀来制备。

2. 发明授权

US5223149A Trivalent silver water treatment compositions 失效
标题翻译：三价银水处理组合物
公开(公告)号：US5223149A
公开(公告)日：1993-06-29
申请号：US884712
申请日：1992-05-18
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： C02F1/50
CPC分类号： C02F1/505 , C02F2103/42 , Y10S422/905
摘要： A method for controlling the growth of bacteria and algae in utilitarian bodies of water such as industrial cooling towers, swimming pools and hot tubs is described. The method comprises adding to the water novel trivalent silver compounds. Said compounds are light stable and can be supplied as liquid concentrates which will not precipitate any silver whatsoever from saline waters nor will the concentrates stain skin or discolor surfaces. Said compounds meet the rigid EPA standards of killing 100% of select coliforms within ten minutes and are efficacious at concentrations as low as 1-2 PPM.
摘要翻译：描述了一种用于控制诸如工业冷却塔，游泳池和热水浴缸的水的功利主义体内的细菌和藻类生长的方法。该方法包括向水中加入新型三价银化合物。所述化合物是光稳定的，可作为液体浓缩物供应，其不会从盐水中沉淀出任何银，也不会使浓缩物污染皮肤或变色表面。所述化合物满足严格的EPA标准，在十分钟内杀死100％的选择大肠杆菌，并且在低至1-2PPM的浓度下是有效的。

3. 发明授权

US06258385B1 Tetrasilver tetroxide treatment for skin conditions 失效
标题翻译：四氯化钛治疗皮肤病
公开(公告)号：US06258385B1
公开(公告)日：2001-07-10
申请号：US09552172
申请日：2000-04-18
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A61K3338
CPC分类号： A61Q19/00 , A61K8/0208 , A61K8/19 , A61K9/0014 , A61K9/06 , A61K33/245 , A61K33/26 , A61K33/32 , A61K33/34 , A61K33/38 , A61K47/02 , A61Q1/12 , Y10S514/859 , Y10S514/861 , Y10S514/863 , Y10S514/925 , Y10S514/928 , Y10S514/931 , Y10S514/934 , Y10S514/937 , Y10S514/938 , Y10S514/969
摘要： The invention relates to the use of electron active molecular crystals comprising tetrasilver tetroxide (Ag4O4) for the treatment and cure of dermatological skin conditions (diseases) ranging from dermatitis, acne and psoiasis to herpes and skin ulcers.
摘要翻译：本发明涉及包含四氧化四砷（Ag 4 O 4）的电子活性分子晶体用于治疗和治愈皮炎，痤疮和皮疹的皮肤病学皮肤病（疾病）到疱疹和皮肤溃疡。

4. 发明授权

US5676977A Method of curing AIDS with tetrasilver tetroxide molecular crystal devices 失效
标题翻译：用四氧化四铁分子晶体装置治疗艾滋病的方法
公开(公告)号：US5676977A
公开(公告)日：1997-10-14
申请号：US658955
申请日：1996-05-31
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A61K33/38
CPC分类号： A61K33/38
摘要： The diamagnetic semiconducting molecular crystal tetrasilver tetroxide (Ag.sub.4 O.sub.4) is utilized for destroying the AIDS virus, destroying AIDS synergistic pathogens and immunity suppressing moieties (ISM) in humans. A single intravenous injection of the devices is all that is required for efficacy at levels of about 40 PPM of human blood. The device molecular crystal contains two mono and two trivalent silver ions capable of "firing" electrons capable of electrocuting the AIDS virus, pathogens and ISM. When administered into the bloodstream, the device electrons will be triggered by pathogens, a proliferating virus and ISM, and when fired will simultaneously trigger a redox chelation mechanism resulting in divalent silver moieties which chelate and bind active sites of the entities destroying them. The devices are completely non-toxic. However, they put stress on the liver causing hepatomegaly, but there is no loss of liver function.
摘要翻译：抗氧化半导体分子晶体四氧化四砷（Ag4O4）用于破坏艾滋病病毒，破坏艾滋病协同病原体和人体免疫抑制部分（ISM）。单次静脉注射的装置全部是在约40PPM人血液中的功效所需要的。器件分子晶体含有能够“烧制”能够电切艾滋病病毒，病原体和ISM的电子的两个一价和两价三价银离子。当被施用到血液中时，器官电子将被病原体，增殖病毒和ISM引发，并且当被引发时将同时触发氧化还原螯合机制，导致二价银部分螯合并结合破坏它们的实体的活性位点。设备完全无毒。但是，他们强调肝脏引起肝肿大，但肝功能没有损失。

5. 发明授权

US5571520A Molecular crystal redox device for pharmaceuticals 失效
标题翻译：用于药物的分子晶体氧化还原装置
公开(公告)号：US5571520A
公开(公告)日：1996-11-05
申请号：US286007
申请日：1994-08-04
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A01N59/16 , A61K8/19 , A61K9/00 , A61K33/38 , A61K47/02 , A61Q17/00
CPC分类号： A61K9/0014 , A01N59/16 , A61K33/38 , A61K47/02 , A61K8/19 , A61K9/0019 , A61Q17/005 , A61K2800/524
摘要： The employment of molecular crystals as bactericidal, viricidal and algicidal devices, and specifically the molecular semiconductor crystal tetrasilver tetroxide Ag.sub.4 O.sub.4 which has two trivalent and two monovalent silver atoms per molecule, and which through this structural configuration generates electronic activity on a molecular scale capable of killing algae and bacteria via the same mechanism as macroscale electron generators.
摘要翻译：使用分子晶体作为杀菌，杀病毒和杀藻装置，特别是分子半导体晶体四分子四氧化物Ag 4 O 4，其每分子具有两个三价和两个一价银原子，并且通过该结构构型在能够杀死的分子量级上产生电子活性藻类和细菌通过与宏观电子发生器相同的机制。

6. 发明授权

US06645531B1 Multivalent electron active compositions and methods of making and using same 失效
标题翻译：多价电子活性组合物及其制备和使用方法
公开(公告)号：US06645531B1
公开(公告)日：2003-11-11
申请号：US09692126
申请日：2000-10-20
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A61K3334
CPC分类号： A61K8/0208 , A61K8/19 , A61K9/0014 , A61K9/06 , A61K33/24 , A61K33/245 , A61K33/26 , A61K33/32 , A61K33/34 , A61K33/38 , A61K47/02 , A61Q1/12 , A61Q19/00 , C01G3/02 , Y02A50/481
摘要： The present invention is directed to pharmaceutical compositions that include a therapeutically effective amount of at least one electron active compound, or a pharmaceutically acceptable derivative thereof, that has at least two polyvalent cations, at least one of which has a first valence state and at least one of which has a second, different valence state. Preferred compounds include Bi(III,V) oxide, Co(II,III) oxide, Cu(I,III) oxide, Fe(II,III) oxide, Mn(II,III) oxide, and Pr(III,IV) oxide, and optionally Ag(I,III) oxide. These compounds may be in a crystalline state having metallic cations of two different valences, or electronic states, in the inorganic crystal. In addition, the invention relates to methods for prevention, management, or treatment of a condition using these compounds or pharmaceutical compositions including the same.
摘要翻译：本发明涉及包含治疗有效量的至少一种电子活性化合物或其药学上可接受的衍生物的药物组合物，其具有至少两种多价阳离子，其中至少一种具有第一价态和至少一种其中一个具有第二个不同的价态。优选的化合物包括氧化物Bi（III），氧化物（II），氧化物（I），氧化物（III），氧化物（II），氧化物（III）），氧化物（II）氧化物和任选的Ag（I，III）氧化物。这些化合物可以是在无机晶体中具有两种不同价态的金属阳离子或电子态的结晶状态。此外，本发明涉及使用这些化合物或包含其的药物组合物的病症的预防，治疗或治疗方法。

7. 发明授权

US5336499A Molecular crystal device for pharmaceuticals 失效
标题翻译：药用分子晶体装置
公开(公告)号：US5336499A
公开(公告)日：1994-08-09
申请号：US971933
申请日：1992-11-05
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A01N59/16 , A61K8/19 , A61K9/00 , A61K33/38 , A61K47/02 , A61Q17/00 , A61K7/00
CPC分类号： A61K9/0014 , A01N59/16 , A61K33/38 , A61K47/02 , A61K8/19 , A61K9/0019 , A61Q17/005 , A61K2800/524
摘要： A novel molecular scale device is described which is bactericidal, fungicidal, viricidal and algicidal. The anti-pathogenic properties of the device are attributed to electron activity indigenous to diamagnetic semiconducting crystals of tetrasilver tetroxide (Ag.sub.4 O.sub.4) which contains two monovalent and two trivalent silver ions in each molecular crystal. When the crystals are activated with an oxidizing agent, they release electrons equivalent to 6.4.times.10.sup.-19 watts per molecule which in effect electrocute pathogens. A multitude of these devices are effective at such low concentrations as 0.3 PPM used as preservatives in a variety of formulations ranging from cosmetics to pharmaceuticals. Indeed, they are intended as active ingredients for pharmaceuticals formulated to destroy such pathogens as Staphylococcus aureus, and epidermidis, the latter of which it completely destroys in a nutrient broth culture of about 1 million organisms at 0.6 PPM, or Candida albercans, the vaginal yeast infection at 2.5 PPM, and the AIDS virus at 18 PPM.
摘要翻译：描述了一种新颖的分子标尺装置，其具有杀菌，杀真菌，杀病毒和杀藻剂。该装置的抗病原性质归因于在四分子四氧化物（Ag4O4）中含有两个一价和两价三价银离子的抗磁半导体晶体的电子活性。当晶体被氧化剂活化时，它们释放相当于每分子6.4×10-19瓦特的电子，其实际上电致病菌。许多这些装置在如化合物到制药的各种制剂中用作防腐剂的0.3PPM这样低的浓度下是有效的。实际上，它们旨在作为用于破坏金黄色葡萄球菌等病原体的药物的活性成分，表皮葡萄球菌（表皮葡萄球菌）在0.6PPM的约100万个生物体的营养液培养物中完全破坏，或者是白色念珠菌，阴道酵母感染2.5 PPM，艾滋病病毒18 PPM。

8. 发明授权

US5098582A Divalent silver oxide bactericides 失效
标题翻译：二价氧化银杀菌剂
公开(公告)号：US5098582A
公开(公告)日：1992-03-24
申请号：US697782
申请日：1991-05-09
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A01N59/16 , C02F1/50 , C02F1/72
CPC分类号： C02F1/505 , C02F1/722 , C02F2103/42 , Y10S422/905
摘要： Divalent silver oxide provides a source for divalent bactericidal silver ions in the presence of persulfate. This oxide is especially effective when applied to water used in industrial cooling towers, hot tubs and swimming pools and conforms to stringent EPA requirements of 100% kills of 100K/cc Streptococcus faecalis within 10 minutes. The oxide also can be used in water with exceptionally high salt content without halide curdy precipitate formation and will not stain the skin of users who may inadvertently be exposed to it.
摘要翻译：二价氧化银在过硫酸盐存在下提供二价杀菌银离子的来源。当应用于工业冷却塔，热水浴缸和游泳池中使用的水时，该氧化物特别有效，并符合严格的EPA要求，在10分钟内100％杀死100K / cc粪肠球菌。氧化物也可以用于盐度非常高的水中，不会产生卤化物凝胶沉淀物形成，并且不会使可能不经意地暴露于其中的使用者的皮肤污染。

9. 发明授权

US5078902A Divalent silver halide bactericide 失效
标题翻译：二价卤化银杀菌剂
公开(公告)号：US5078902A
公开(公告)日：1992-01-07
申请号：US697783
申请日：1991-05-09
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： C02F1/50
CPC分类号： C02F1/505 , C02F2103/42
摘要： Divalent silver halides provide a source for divalent bactericidal silver ions in the presence of persulfate. The halides are especially effective when applied to water used in industrial cooling installations, hot tubs and swimming pools and will conform to stringent EPA requirements for waters utilized for bathing as in tubs and pools of 100% kills of 100 K/cc E. Coli coliforms within 10 minutes, exemplary of which are the chloride and bromide which give 100% kills within 5 minutes. The halides, of course, can be used in salty water since they are solids immune from halide action that would otherwise precipitate soluble divalent silver from solution.
摘要翻译：二价卤化银在过硫酸盐存在下提供二价杀菌银离子的来源。当适用于工业冷却装置，热水浴缸和游泳池中使用的水时，卤化物特别有效，并符合EPA所规定的用于沐浴的水，如100％杀死100K / cc大肠杆菌的桶和池。大肠杆菌在10分钟内，其示例是在5分钟内产生100％杀死的氯化物和溴化物。当然，卤化物可以在咸水中使用，因为它们是固体免于卤化物作用，否则会从溶液中沉淀出可溶性二价银。

10. 发明授权

US06485755B1 Methods of using electron active compounds for managing cancer 有权
标题翻译：使用电子活性化合物治疗癌症的方法
公开(公告)号：US06485755B1
公开(公告)日：2002-11-26
申请号：US09692488
申请日：2000-10-20
申请人： Marvin S. Antelman
发明人： Marvin S. Antelman
IPC分类号： A61K3338
CPC分类号： A61K8/0208 , A61K8/19 , A61K9/0014 , A61K9/0019 , A61K9/06 , A61K33/24 , A61K33/245 , A61K33/26 , A61K33/32 , A61K33/34 , A61K33/38 , A61K45/06 , A61K47/06 , A61Q1/12 , A61Q19/00 , C01G3/02
摘要： The present invention provides methods for preventing, treating, and/or managing one or more cancerous conditions in a patient, such as a human. A multivalent metal oxide, such as Ag(I,III), Cu(I,III), Pr(III,IV), and Bi(III,V) oxides or a pharmaceutically acceptable derivative thereof, may be administered to the patient in an amount and for a period of time which is therapeutically effective to prevent, treat, and/or manage such condition(s). These cancerous conditions include systemic and external cancers, and may also include conditions and symptoms associated with cancer. The present invention also provides a pharmaceutical composition suitable for treating such cancerous conditions. The compositions of the invention may be adapted for at least one of subcutaneous injection, intramuscular injection, intravenous injection, infusion, transdermal, or topical application.
摘要翻译：本发明提供了用于预防，治疗和/或控制患者（例如人）中的一种或多种癌症的方法。可以向患者施用多价金属氧化物，例如Ag（I，III），Cu（I，III），Pr（III，IV）和Bi（III，V）氧化物或其药学上可接受的衍生物治疗和/或管理这些病症的治疗有效量和一段时间。这些癌症状况包括全身和外部癌症，并且还可包括与癌症相关的病症和症状。本发明还提供了适用于治疗这种癌症的药物组合物。本发明的组合物可以适用于皮下注射，肌内注射，静脉内注射，输注，透皮或局部应用中的至少一种。

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