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1. 发明申请

US20100030117A1 SYSTEMS AND METHODS FOR MONITORING ERECTILE FUNCTION AND DIAGNOSING ERECTILE DYSFUNCTION 审中-公开
标题翻译：用于监测功能和诊断功能的系统和方法
公开(公告)号：US20100030117A1
公开(公告)日：2010-02-04
申请号：US12525078
申请日：2008-02-02
申请人： Luya Li , Sidney Ben Radomski
发明人： Luya Li , Sidney Ben Radomski
IPC分类号： A61B5/103
CPC分类号： A61B5/0059 , A61B5/4393
摘要： Methods and systems for monitoring erectile function or dysfunction provide for determining concentration data of biochemical compounds in a subject's erectile tissues; and analyzing the concentration data to yield values indicative of the subject's erectile function. The concentration of biochemical compounds may be measured using Near Infrared Spectroscopy (NIRS). The biochemical compounds may comprise at least one compound from the group consisting of Hemoglobin, Oxygenated Hemoglobin, Cytochromes and Myoglobin.
摘要翻译：用于监测勃起功能或功能障碍的方法和系统提供用于确定受试者勃起组织中生化化合物的浓度数据; 并分析浓度数据以产生指示受试者勃起功能的值。可以使用近红外光谱（NIRS）测量生物化学化合物的浓度。生化化合物可以包含至少一种由血红蛋白，氧合血红蛋白，细胞色素和肌红蛋白组成的组的化合物。

2. 发明授权

US07263396B2 Ear sensor assembly 有权
标题翻译：耳传感器组件
公开(公告)号：US07263396B2
公开(公告)日：2007-08-28
申请号：US10900146
申请日：2004-07-28
申请人： Yunquan Chen , Luya Li , Rakesh Kumar Sethi , Ming Sun , Christopher Grant Denny , Scott Howard Phillips
发明人： Yunquan Chen , Luya Li , Rakesh Kumar Sethi , Ming Sun , Christopher Grant Denny , Scott Howard Phillips
IPC分类号： A61B5/00
CPC分类号： A61B5/14552 , A61B5/6816
摘要： A sensor assembly for monitoring physiological characteristics interfaces to a subject's ear. The sensor assembly has a projection that projects into the subject's concha. The projection may have a notch to accommodate the subject's anti-tragus. A clip connected to the projection holds a sensor against the subject's lobule. The sensor may comprise a pulse-oximetry-type sensor.
摘要翻译：用于监测生理特征的传感器组件与受试者的耳朵接口。传感器组件具有投影到被检者的外观中的突出部。该投影可以具有凹口以适应受试者的反耳屏。连接到突起的夹子将传感器保持在对象的小叶上。传感器可以包括脉搏血氧测定型传感器。

3. 发明申请

US20100145169A1 METHODS AND SYSTEMS FOR DETECTING A CONDITION OF COMPARTMENT SYNDROME 审中-公开
标题翻译：检测室内情况的方法和系统
公开(公告)号：US20100145169A1
公开(公告)日：2010-06-10
申请号：US12517054
申请日：2007-11-30
申请人： Luya Li , Qichao Zhu , Phaik Koay , Matthew Peter Walls
发明人： Luya Li , Qichao Zhu , Phaik Koay , Matthew Peter Walls
IPC分类号： A61B5/1455
CPC分类号： A61B5/14546 , A61B5/1455
摘要： Methods and systems for detecting and alerting one to a condition of Compartment Syndrome provide for determining concentration data of biochemical compounds in tissues, preferably at a shallow depth beneath the skin; analysing the concentration data to detect a condition of Compartment Syndrome; and triggering an alarm if a condition of Compartment Syndrome is detected. The concentration of biochemical compounds may be measured using Near Infrared Spectroscopy. The biochemical compounds may comprise at least one compound from the group consisting of Hemoglobin, Oxygenated Hemoglobin, Cytochromes and Myoglobin.
摘要翻译：用于检测和警告一个至病房综合征状况的方法和系统提供了确定组织中生物化学化合物的浓度数据，优选在皮肤下面的浅层深度; 分析浓度数据以检测病房综合征状况; 如果检测到隔间综合症状况，则触发警报。生物化学化合物的浓度可以使用近红外光谱来测量。生化化合物可以包含至少一种由血红蛋白，氧合血红蛋白，细胞色素和肌红蛋白组成的组的化合物。

4. 发明申请

US20100130880A1 APPARATUS AND METHODS FOR MONITORING BLOOD FLOW IN THE PROSTRATE GLAND 审中-公开
标题翻译：用于监测前列腺中血液流动的装置和方法
公开(公告)号：US20100130880A1
公开(公告)日：2010-05-27
申请号：US12595338
申请日：2008-04-16
申请人： Luya Li
发明人： Luya Li
IPC分类号： A61B5/0265
CPC分类号： A61B5/0261 , A61B5/0075 , A61B5/0086 , A61B5/0507 , A61B5/4381 , A61B8/06 , A61B8/12 , A61B18/18 , A61B2018/1807
摘要： A system for detecting blood flow in the prostate comprises a blood flow sensor disposed on a catheter that can be inserted into a subject's urethra so that the blood flow sensor is located to detect blood flow in the subject's prostate gland. The sensor may be a sensor of a near infrared spectroscopy (NIRS) system configured to detect in the prostate one or more biocompounds indicative of blood flow. An output of the sensor may provide an input to a controller for a heater disposed to heat tissues of the prostate. Some embodiments comprise one or more additional sensors for detecting blood flow and/or temperature of a portion of the subject's rectal wall adjacent to the prostate gland. In such embodiments, outputs from the additional sensors may provide additional inputs to the controller.
摘要翻译：用于检测前列腺中的血液流动的系统包括设置在导管上的血液流量传感器，其可插入到受检者的尿道中，使得血液流量传感器位于以检测受试者的前列腺中的血液流动。传感器可以是近红外光谱（NIRS）系统的传感器，其被配置为在前列腺中检测一个或多个指示血流的生物化合物。传感器的输出可以为控制器提供输入，用于加热器，其被设置为加热前列腺的组织。一些实施例包括用于检测与前列腺相邻的受试者的直肠壁的一部分的血流和/或温度的一个或多个附加传感器。在这样的实施例中，来自附加传感器的输出可以向控制器提供额外的输入。

5. 发明授权

US06599251B2 Continuous non-invasive blood pressure monitoring method and apparatus 有权
标题翻译：连续非侵入性血压监测方法及装置
公开(公告)号：US06599251B2
公开(公告)日：2003-07-29
申请号：US09917279
申请日：2001-07-27
申请人： Yunquan Chen , Luya Li , Cecil Hershler , Ryan Peter Dill
发明人： Yunquan Chen , Luya Li , Cecil Hershler , Ryan Peter Dill
IPC分类号： A61B502
CPC分类号： A61B5/4884 , A61B5/021 , A61B5/02125 , A61B5/02255 , A61B5/0285 , A61B5/7278
摘要： A non-invasive apparatus and method for monitoring the blood pressure of a subject detects a pulse signal at both a first and second location on the subject's body. The elapsed time between the arrival of corresponding points of the pulse signal at the first and second locations is determined. Blood pressure is related to the elapsed time by relationships such as: P=a+b ln(T) where a and b are constants dependent upon the nature of the subject and the signal detecting devices. The system can be calibrated by measuring a single pair of reference blood pressure and corresponding elapsed time.
摘要翻译：用于监测被检者的血压的非侵入性装置和方法在被检体的第一和第二位置检测脉搏信号。确定在第一和第二位置处的脉冲信号的相应点到达之间的经过时间。血压与经过的时间有关，例如：其中a和b是取决于受试者的性质和信号检测装置的常数。可以通过测量一对参考血压和相应的经过时间来校准系统。

6. 发明授权

US06503206B1 Apparatus having redundant sensors for continuous monitoring of vital signs and related methods 有权
标题翻译：具有用于连续监测生命体征和相关方法的冗余传感器的装置
公开(公告)号：US06503206B1
公开(公告)日：2003-01-07
申请号：US09917608
申请日：2001-07-27
申请人： Luya Li , Yunquan Chen , Rakesh Kumar Sethi , Ming Sun
发明人： Luya Li , Yunquan Chen , Rakesh Kumar Sethi , Ming Sun
IPC分类号： A61B502
CPC分类号： A61B5/02125 , A61B5/0205 , A61B5/024 , A61B5/1455
摘要： Apparatus for monitoring one or more vital signs of a subject has a number of sensors. There is at least one redundant sensor. Each sensor originates a signal. A selection system determines performance criteria for a number of groups of signals. Each group includes one or more signals. The apparatus computes a predicted value for a vital sign by either computing a value from each group of signals and taking a weighted average with weights based upon the performance criterion or by selecting one of the groups of signals for which the performance criterion is best and computing the output value from that group of signals. The output values are relatively insensitive to artifacts and to errors caused by the disconnection or malfunctioning of one sensor.
摘要翻译：用于监测受试者的一个或多个生命体征的装置具有多个传感器。至少有一个冗余传感器。每个传感器产生一个信号。选择系统确定多组信号的性能标准。每组包括一个或多个信号。该装置通过计算来自每组信号的值并且基于性能标准采取具有权重的加权平均值或通过选择性能标准最佳的信号组中的一个来计算生命体征的预测值，并且计算来自该组信号的输出值。输出值对于伪影和由一个传感器的断开或故障引起的错误相对不敏感。

7. 发明申请

US20100087752A1 ASSESSMENT OF URINARY SYSTEM FUNCTION BY PATTERN MATCHING 审中-公开
标题翻译：通过模式匹配评估URINARY系统功能
公开(公告)号：US20100087752A1
公开(公告)日：2010-04-08
申请号：US12532624
申请日：2008-03-20
申请人： Luya Li , Raymond Jacob Becker , Matthew Peter Walls
发明人： Luya Li , Raymond Jacob Becker , Matthew Peter Walls
IPC分类号： A61B5/05 , A61B5/103
CPC分类号： A61B5/202 , A61B5/14507 , A61B5/208
摘要： A system for monitoring urinary system operation comprises a sensor for detecting a level of one or more compounds in tissues of a subject's bladder. A processor identifies a pattern in a time variation of the level detected by the sensor. The processor generates an indicator of bladder function based at least in part on the identified pattern. In some embodiments the processor generates a possible diagnosis based upon the identified pattern and one or more pieces of additional information. The additional information may comprise one or more of: a residual amount of urine after urination; a maximum uroflow rate; and, a delay in onset of urination.
摘要翻译：用于监测泌尿系统操作的系统包括用于检测受试者膀胱组织中的一种或多种化合物的水平的传感器。处理器识别由传感器检测到的电平的时间变化中的图案。处理器至少部分地基于所识别的模式来生成膀胱功能的指示符。在一些实施例中，处理器基于所识别的模式和一个或多个附加信息生成可能的诊断。附加信息可以包括以下中的一种或多种：排尿后尿液的残留量; 最大尿流率; 以及排尿发作的延迟。

8. 发明申请

US20100084557A1 LIGHT INTENSITY CONTROL FOR NEAR INFRARED SPECTROSCOPY 审中-公开
标题翻译：近红外光谱的光强度控制
公开(公告)号：US20100084557A1
公开(公告)日：2010-04-08
申请号：US12598419
申请日：2008-05-01
申请人： Phaik Sun Koay , Qichao Zhu , Luya Li
发明人： Phaik Sun Koay , Qichao Zhu , Luya Li
IPC分类号： G01J3/02 , G01J5/02
CPC分类号： A61B5/0059 , G01J3/108 , G01J3/42 , G01N21/255 , G01N21/359 , G01N2201/0612 , G01N2201/0627
摘要： A system for near infrared spectroscopy includes a controller that automates selection of light intensities for one or more light sources. The system may stepwise increase or decrease a current driving a light source until a signal received at a light detector is within a desired range. The system may maintain closed loop control over the intensity of a light source after the intensity has been set. The closed loop control may be based on a signal from a second light detector that senses light from the light source. Current/intensity settings may be established for each of multiple light detectors. In response to selection of a light detector, the corresponding current may be delivered to drive the light source.
摘要翻译：用于近红外光谱的系统包括自动选择一个或多个光源的光强度的控制器。系统可以逐步增加或减少驱动光源的电流，直到在光检测器处接收的信号在期望的范围内。该系统可以在设定强度后，对光源的强度进行闭环控制。闭环控制可以基于来自感测来自光源的光的第二光检测器的信号。可以为多个光检测器中的每一个建立电流/强度设置。响应于光检测器的选择，可以传送相应的电流以驱动光源。

9. 发明申请

US20090076398A1 Continuous Non-Invasive Blood Pressure Measurement Apparatus and Methods Providing Automatic Recalibration 有权
标题翻译：连续无创血压测量装置和方法提供自动重新校准
公开(公告)号：US20090076398A1
公开(公告)日：2009-03-19
申请号：US12275453
申请日：2008-11-21
申请人： Luya Li , Rakesh Kumar Sethi , Ming Sun , Alexander Yuk Sit , Yong Liu
发明人： Luya Li , Rakesh Kumar Sethi , Ming Sun , Alexander Yuk Sit , Yong Liu
IPC分类号： A61B5/02
CPC分类号： A61B5/022 , A61B5/021 , A61B5/02116 , A61B5/02125 , A61B5/0225 , A61B5/7239
摘要： A blood pressure measurement system is configured to perform a calibration automatically when a calibration condition is satisfied. The calibration condition is based upon one or more parameters of pulse waves of a subject. The parameters may include pulse wave area; a time difference between systolic peak and reflected wave peak or dichrotic notch in the pulse wave and a shape of at least a portion of the pulse wave.
摘要翻译：血压测量系统被配置为当满足校准条件时自动执行校准。校准条件基于受试者的脉搏波的一个或多个参数。参数可能包括脉搏波区域; 脉搏波中的收缩峰值与反射波峰值或二色性切口之间的时间差以及脉搏波的至少一部分的形状。

10. 发明授权

US07455643B1 Continuous non-invasive blood pressure measurement apparatus and methods providing automatic recalibration 有权
标题翻译：连续非侵入性血压测量仪器和方法提供自动重新校准
公开(公告)号：US07455643B1
公开(公告)日：2008-11-25
申请号：US11015033
申请日：2004-12-20
申请人： Luya Li , Rakesh Kumar Sethi , Ming Sun , Alexander Yuk Sit , Yong Liu
发明人： Luya Li , Rakesh Kumar Sethi , Ming Sun , Alexander Yuk Sit , Yong Liu
IPC分类号： A61B5/00
CPC分类号： A61B5/022 , A61B5/021 , A61B5/02116 , A61B5/02125 , A61B5/0225 , A61B5/7239
摘要： A blood pressure measurement system is configured to perform a calibration automatically when a calibration condition is satisfied. The calibration condition is based upon one or more parameters of pulse waves of a subject. The parameters may include pulse wave area; a time difference between systolic peak and reflected wave peak or dichrotic notch in the pulse wave and a shape of at least a portion of the pulse wave.
摘要翻译：血压测量系统被配置为当满足校准条件时自动执行校准。校准条件基于受试者的脉搏波的一个或多个参数。参数可能包括脉搏波区域; 脉搏波中的收缩峰值与反射波峰值或二色性切口之间的时间差以及脉搏波的至少一部分的形状。

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