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1. 发明申请

US20090295390A1 LOW FIELD ELECTRON PARAMAGNETIC RESONANCE IMAGING WITH SQUID DETECTION 有权
标题翻译：低场电子参考谐波成像与检测
公开(公告)号：US20090295390A1
公开(公告)日：2009-12-03
申请号：US12359576
申请日：2009-01-26
申请人： Inseob Hahn , Peter K Day , Konstantin I Penanen , Byeong H. Eom , Mark S Cohen
发明人： Inseob Hahn , Peter K Day , Konstantin I Penanen , Byeong H. Eom , Mark S Cohen
IPC分类号： G01R33/60 , G01R33/32
CPC分类号： G01R33/60 , G01R33/326
摘要： In one embodiment, a flux transformer with a gradiometer pickup coil is magnetically coupled to a SQUID, and a SQUID array amplifier comprising a plurality of SQUIDs, connected in series, is magnetically coupled to the output of the SQUID. Other embodiments are described and claimed.
摘要翻译：在一个实施例中，具有梯度计拾取线圈的磁通变压器磁耦合到SQUID，并且包括串联连接的多个SQUID的SQUID阵列放大器磁耦合到SQUID的输出端。描述和要求保护其他实施例。

2. 发明授权

US08179135B2 Low field electron paramagnetic resonance imaging with SQUID detection 有权
标题翻译：低场电子顺磁共振成像与SQUID检测
公开(公告)号：US08179135B2
公开(公告)日：2012-05-15
申请号：US12359576
申请日：2009-01-26
申请人： Inseob Hahn , Peter K. Day , Konstantin I. Penanen , Byeong H. Eom , Mark S. Cohen
发明人： Inseob Hahn , Peter K. Day , Konstantin I. Penanen , Byeong H. Eom , Mark S. Cohen
IPC分类号： G01V3/00
CPC分类号： G01R33/60 , G01R33/326
摘要： In one embodiment, a flux transformer with a gradiometer pickup coil is magnetically coupled to a SQUID, and a SQUID array amplifier comprising a plurality of SQUIDs, connected in series, is magnetically coupled to the output of the SQUID. Other embodiments are described and claimed.
摘要翻译：在一个实施例中，具有梯度计拾取线圈的磁通变压器磁耦合到SQUID，并且包括串联连接的多个SQUID的SQUID阵列放大器磁耦合到SQUID的输出端。描述和要求保护其他实施例。

3. 发明授权

US07671587B2 Low field SQUID MRI devices, components and methods 失效
标题翻译：低场SQUID MRI设备，组件和方法
公开(公告)号：US07671587B2
公开(公告)日：2010-03-02
申请号：US12113130
申请日：2008-04-30
申请人： Konstantin I. Penanen , Byeong H Eom , Inseob Hahn
发明人： Konstantin I. Penanen , Byeong H Eom , Inseob Hahn
IPC分类号： G01V3/00
CPC分类号： G01R33/38 , A61B5/055 , G01R33/0354 , G01R33/326 , G01R33/445
摘要： Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.
摘要翻译：公开了低场SQUID MRI装置，部件和方法。它们包括基于便携式低场（SQUID）的MRI仪器和便携式低场SQUID的MRI系统，该系统在被摄体适于位于的床下操作。还公开了一种在适于与用于分析样品或受试者的NMR或MRI装置一起使用的图像编码线圈系统上分配导线的方法和适用于与基于SQUID的低场MRI装置一起使用的二阶超导梯度计用于与受试者或样本相关的MRI信号的感测部件。

4. 发明授权

US07323869B1 Subranging scheme for SQUID sensors 失效
标题翻译： SQUID传感器的子程序
公开(公告)号：US07323869B1
公开(公告)日：2008-01-29
申请号：US11279137
申请日：2006-04-10
申请人： Konstantin I. Penanen
发明人： Konstantin I. Penanen
IPC分类号： G01R33/02
CPC分类号： G01R33/0354 , G01R33/0358
摘要： A readout scheme for measuring the output from a SQUID-based sensor-array using an improved subranging architecture that includes multiple resolution channels (such as a coarse resolution channel and a fine resolution channel). The scheme employs a flux sensing circuit with a sensing coil connected in series to multiple input coils, each input coil being coupled to a corresponding SQUID detection circuit having a high-resolution SQUID device with independent linearizing feedback. A two-resolution configuration (course and fine) is illustrated with a primary SQUID detection circuit for generating a fine readout, and a secondary SQUID detection circuit for generating a course readout, both having feedback current coupled to the respective SQUID devices via feedback/modulation coils. The primary and secondary SQUID detection circuits function and derive independent feedback. Thus, the SQUID devices may be monitored independently of each other (and read simultaneously) to dramatically increase slew rates and dynamic range.
摘要翻译：一种读出方案，用于使用包括多个分辨率通道（例如粗分辨率通道和精细分辨率通道）的改进的子架构来测量基于SQUID的传感器阵列的输出。该方案采用具有与多个输入线圈串联连接的感测线圈的磁通感测电路，每个输入线圈耦合到具有独立线性化反馈的具有高分辨率SQUID器件的相应SQUID检测电路。示出了具有用于产生精细读出的主SQUID检测电路的双分辨率配置（过程和精细），以及用于产生路线读出的辅助SQUID检测电路，其具有经由反馈/调制耦合到相应SQUID器件的反馈电流线圈初级和次级SQUID检测电路起作用并获得独立的反馈。因此，SQUID设备可以彼此独立地监视（并同时读取），以显着提高压摆率和动态范围。

5. 发明授权

US08487623B2 Low field squid MRI devices, components and methods 有权
标题翻译：低场鱿鱼MRI设备，组件和方法
公开(公告)号：US08487623B2
公开(公告)日：2013-07-16
申请号：US13090931
申请日：2011-04-20
申请人： Konstantin I. Penanen , Byeong H. Eom , Inseob Hahn
发明人： Konstantin I. Penanen , Byeong H. Eom , Inseob Hahn
IPC分类号： G01V3/00 , G01R33/48
CPC分类号： G01R33/38 , A61B5/055 , G01R33/0354 , G01R33/326 , G01R33/445
摘要： Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.
摘要翻译：公开了低场SQUID MRI装置，部件和方法。它们包括基于便携式低场（SQUID）的MRI仪器和便携式低场SQUID的MRI系统，该系统在被摄体适于位于的床下操作。还公开了一种在适于与用于分析样品或受试者的NMR或MRI装置一起使用的图像编码线圈系统上分配导线的方法和适用于与基于SQUID的低场MRI装置一起使用的二阶超导梯度计用于与受试者或样本相关的MRI信号的感测部件。

6. 发明申请

US20090072828A1 LOW FIELD SQUID MRI DEVICES, COMPONENTS AND METHODS 失效
标题翻译：低场SQUID MRI设备，组件和方法
公开(公告)号：US20090072828A1
公开(公告)日：2009-03-19
申请号：US12113130
申请日：2008-04-30
申请人： Konstantin I. PENANEN , Byeong H. Eom , Inseob Hahn
发明人： Konstantin I. PENANEN , Byeong H. Eom , Inseob Hahn
IPC分类号： G01R33/32
CPC分类号： G01R33/38 , A61B5/055 , G01R33/0354 , G01R33/326 , G01R33/445
摘要： Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.
摘要翻译：公开了低场SQUID MRI装置，部件和方法。它们包括基于便携式低场（SQUID）的MRI仪器和便携式低场SQUID的MRI系统，该系统在被摄体适于位于的床下操作。还公开了一种在适于与用于分析样品或受试者的NMR或MRI装置一起使用的图像编码线圈系统上分配导线的方法和适用于与基于SQUID的低场MRI装置一起使用的二阶超导梯度计用于与受试者或样本相关的MRI信号的感测部件。

7. 发明申请

US20110210738A1 LOW FIELD SQUID MRI DEVICES, COMPONENTS AND METHODS 有权
标题翻译：低场SQUID MRI设备，组件和方法
公开(公告)号：US20110210738A1
公开(公告)日：2011-09-01
申请号：US13090931
申请日：2011-04-20
申请人： Konstantin I. PENANEN , Byeong H. EOM , Inseob HAHN
发明人： Konstantin I. PENANEN , Byeong H. EOM , Inseob HAHN
IPC分类号： G01R33/44
CPC分类号： G01R33/38 , A61B5/055 , G01R33/0354 , G01R33/326 , G01R33/445
摘要： Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.
摘要翻译：公开了低场SQUID MRI装置，部件和方法。它们包括基于便携式低场（SQUID）的MRI仪器和便携式低场SQUID的MRI系统，该系统在被摄体适于位于的床下操作。还公开了一种在适于与用于分析样品或受试者的NMR或MRI装置一起使用的图像编码线圈系统上分配导线的方法和适用于与基于SQUID的低场MRI装置一起使用的二阶超导梯度计用于与受试者或样本相关的MRI信号的感测部件。

8. 发明授权

US08008914B2 Low field SQUID MRI devices, components and methods 有权
标题翻译：低场SQUID MRI设备，组件和方法
公开(公告)号：US08008914B2
公开(公告)日：2011-08-30
申请号：US12687104
申请日：2010-01-13
申请人： Konstantin I. Penanen , Byeong H. Eom , Inseob Hahn
发明人： Konstantin I. Penanen , Byeong H. Eom , Inseob Hahn
IPC分类号： G01V3/00
CPC分类号： G01R33/38 , A61B5/055 , G01R33/0354 , G01R33/326 , G01R33/445
摘要： Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.
摘要翻译：公开了低场SQUID MRI装置，部件和方法。它们包括基于便携式低场（SQUID）的MRI仪器和便携式低场SQUID的MRI系统，该系统在被摄体适于位于的床下操作。还公开了一种在适于与用于分析样品或受试者的NMR或MRI装置一起使用的图像编码线圈系统上分配导线的方法和适用于与基于SQUID的低场MRI装置一起使用的二阶超导梯度计用于与受试者或样本相关的MRI信号的感测部件。

9. 发明申请

US20100109669A1 LOW FIELD SQUID MRI DEVICES, COMPONENTS AND METHODS 有权
标题翻译：低场SQUID MRI设备，组件和方法
公开(公告)号：US20100109669A1
公开(公告)日：2010-05-06
申请号：US12687104
申请日：2010-01-13
申请人： Konstantin I. PENANEN , Byeong H. EOM , Inseob HAHN
发明人： Konstantin I. PENANEN , Byeong H. EOM , Inseob HAHN
IPC分类号： G01R33/44
CPC分类号： G01R33/38 , A61B5/055 , G01R33/0354 , G01R33/326 , G01R33/445
摘要： Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.
摘要翻译：公开了低场SQUID MRI装置，部件和方法。它们包括基于便携式低场（SQUID）的MRI仪器和便携式低场SQUID的MRI系统，该系统在被摄体适于位于的床下操作。还公开了一种在适于与用于分析样品或受试者的NMR或MRI装置一起使用的图像编码线圈系统上分配导线的方法和适用于与基于SQUID的低场MRI装置一起使用的二阶超导梯度计用于与受试者或样本相关的MRI信号的感测部件。

10. 发明申请

US20090322324A1 GEOMETRIES FOR SUPERCONDUCTING SENSING COILS FOR SQUID-BASED SYSTEMS 审中-公开
标题翻译：用于基于SQUID的系统超导传感线圈的几何
公开(公告)号：US20090322324A1
公开(公告)日：2009-12-31
申请号：US12113163
申请日：2008-04-30
申请人： Konstantin I. PENANEN , Byeong H. Eom , Inseob Hahn
发明人： Konstantin I. PENANEN , Byeong H. Eom , Inseob Hahn
IPC分类号： G01R33/02
CPC分类号： G01R33/0354 , G01R33/326 , G01R33/60
摘要： Geometries for superconducting sensing coils for SQUID-based systems are described, such as a superconducting sensing coil with a flat washer shape the inner diameter of which has an extension which is a small fraction of the extension of the outer diameter. Also described are a second-order gradiometer comprising such coils and a superconducting sensing coil structure comprising an external low-melting point metallic loop encapsulating one or more superconductive coil loops, together with a heterogeneous superconductive sensing wire for gradiometers, consisting of an internal copper skeleton surrounded by an external lead-tin alloy.
摘要翻译：描述了用于基于SQUID的系统的超导感测线圈的几何形状，例如具有平坦垫圈形状的超导感测线圈，其内径具有作为外径的延伸部分的一小部分的延伸。还描述了包括这种线圈的二阶梯度计和包括外部低熔点金属环的超导感应线圈结构，该外部低熔点金属环封装一个或多个超导线圈环，以及用于梯度计的异质超导感应线，由内部铜骨架被外部铅锡合金包围。

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