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1. 发明授权

US08263286B2 Membrane-electrode assembly and polymer electrolyte fuel cell 有权
标题翻译：膜 - 电极组件和聚合物电解质燃料电池
公开(公告)号：US08263286B2
公开(公告)日：2012-09-11
申请号：US12812901
申请日：2009-01-28
申请人： Shinji Nakai , Keiji Kubo , Tomohiro Ono , Hiroyuki Ohgi
发明人： Shinji Nakai , Keiji Kubo , Tomohiro Ono , Hiroyuki Ohgi
IPC分类号： H01M8/10
CPC分类号： H01M8/1004 , H01M8/1023 , H01M8/1053 , H01M2008/1095 , H01M2300/0082
摘要： A membrane-electrode assembly for polymer electrolyte fuel cells comprising a polymer electrolyte membrane and two gas diffusion electrodes being bonded to the membrane so that the membrane can be between them, in which assembly each gas diffusion electrode is comprised of an electrode catalyst layer and a gas diffusion layer, intermediate layer(s) being an ion conductor is/are arranged between the electrode catalyst layer(s) and the membrane, the ion conductor mainly comprises a block copolymer comprising a polymer block (A) having ion-conductive groups and a polymer block (B) having no ion-conductive group, both blocks phase-separate from each other, (A) forms a continuous phase, and the contact part(s) of the intermediate layer(s) with the polymer electrolyte membrane and the contact part(s) of the intermediate layer(s) with the electrode catalyst layer(s) are comprised of polymer block (A) having ion-conductive groups; and a polymer electrolyte fuel cell wherein the assembly is used. By the invention, a membrane-electrode assembly and a fuel cell are provided which are economical, environment-friendly, good in moldability, and small in interface resistance and excellent in power generation efficiency.
摘要翻译：一种用于聚合物电解质燃料电池的膜 - 电极组件，包括聚合物电解质膜和两个气体扩散电极，所述两个气体扩散电极结合到膜上，使得膜可以在它们之间，其中每个气体扩散电极由电极催化剂层和气体扩散层，作为离子导体的中间层设置在电极催化剂层和膜之间，离子导体主要包含含有具有离子传导性基团的聚合物嵌段（A）和不具有离子传导性基团的聚合物嵌段（B）彼此相分离，（A）形成连续相，中间层与高分子电解质膜的接触部分和中间层与电极催化剂层的接触部分由具有离子传导性基团的聚合物嵌段（A）组成; 以及其中使用所述组件的聚合物电解质燃料电池。通过本发明，提供了经济，环保，成型性好，界面电阻小，发电效率优异的膜 - 电极组件和燃料电池。

2. 发明授权

US07534887B2 Thiazoline derivative and use of the same 失效
标题翻译：噻唑啉衍生物和使用相同
公开(公告)号：US07534887B2
公开(公告)日：2009-05-19
申请号：US10574048
申请日：2004-09-29
申请人： Keiji Kubo , Takanobu Kuroita , Masaki Kawamura , Hiroki Sakamoto
发明人： Keiji Kubo , Takanobu Kuroita , Masaki Kawamura , Hiroki Sakamoto
IPC分类号： C07D413/00 , A61K31/497
CPC分类号： C07D417/06 , C07D277/42 , C07D417/04 , C07D417/12
摘要： A thiazoline derivative represented by Formula (I): wherein R is a cyclic hydrocarbon group which may be substituted, or a heterocyclic group which may be substituted; X is a bond or a divalent chain hydrocarbon group which may be substituted; X′ is a bond or —N(R5)—; Y is a divalent hydrocarbon group which may be substituted; Y′ is a bond or —C(═O)—; ring A is a nitrogen-containing heterocycle which may be substituted; Z1 and Z3 are each independently a bond or a divalent chain hydrocarbon group which may be substituted; Z2 is a bond or —N(R6)—; and B is a group represented by the formula: which is useful as a therapeutic drug for thrombosis, is provided.
摘要翻译：由式（I）表示的噻唑啉衍生物：其中R是可被取代的环状烃基或可被取代的杂环基; X是可以被取代的键或二价链烃基; X'是键或-N（R 5） - ; Y是可以被取代的二价烃基; Y'是键或-C（-O） - ; 环A是可以被取代的含氮杂环; Z 1和Z 3各自独立地为可被取代的键或二价链烃基; Z2是键或-N（R6） - ; 并且B是由下式表示的基团：其可用作血栓形成的治疗药物。

3. 发明申请

US20080255362A1 Cyclic amide derivative, and its production and use 审中-公开
公开(公告)号：US20080255362A1
公开(公告)日：2008-10-16
申请号：US12157573
申请日：2008-06-11
申请人： Keiji Kubo , Yasuhiro Imaeda
发明人： Keiji Kubo , Yasuhiro Imaeda
IPC分类号： C07D211/40
CPC分类号： C07D211/76 , C07D401/04 , C07D403/04 , C07D413/04 , C07D417/04
摘要： The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(═NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2)(R2′)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3′)—, —N(R3)—, etc., or a salt thereof.

4. 发明申请

US20080255352A1 Cyclic amide derivative, and its production and use 审中-公开
标题翻译：环状酰胺衍生物及其生产和使用
公开(公告)号：US20080255352A1
公开(公告)日：2008-10-16
申请号：US12157574
申请日：2008-06-11
申请人： Keiji Kubo , Yasuhiro Imaeda
发明人： Keiji Kubo , Yasuhiro Imaeda
IPC分类号： C07D413/04
CPC分类号： C07D211/76 , C07D401/04 , C07D403/04 , C07D413/04 , C07D417/04
摘要： The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(═NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2)(R2′)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3′)—, —N(R3)—, etc., or a salt thereof.
摘要翻译：本发明提供用作治疗血栓形成的药物的环状酰胺衍生物，其由式（I）表示：其中R 1表示任选取代的环状烃基或任选取代的杂环基， W表示键或任选取代的二价链烃基，a表示0,1或2，X 1表示任选取代的低级亚烷基或任选取代的低级亚烯基，Y 1， / O 2表示-C（O） - ， - S（O） - 或-S（O）2 - ，A表示可被进一步取代的哌嗪环或可以是进一步取代的X 2表示键或任选取代的低级亚烷基，Y 2表示-C（O） - ， - S（O） - ， - S（O ）2 - 或-C（-NR 7） - ，X 3表示任选取代的C 1-4烷基 >亚烷基或任选取代的C 2-4亚烯基，Z 3表示-N（R -O - 或键，Z 1表示-C（R 2）2（R 2）（R 2） - ， - （R 2） - 等，Z 2表示-C（R 3）（3）， - （R 3） - 等，或其盐。

5. 发明申请

US20070244118A1 Cyclic Amide Derivative, and Its Production and Use 有权
标题翻译：环酰胺衍生物及其生产和使用
公开(公告)号：US20070244118A1
公开(公告)日：2007-10-18
申请号：US11596089
申请日：2005-05-20
申请人： Keiji Kubo , Yasuhiro Imaeda
发明人： Keiji Kubo , Yasuhiro Imaeda
IPC分类号： C07D211/76 , A61K31/45 , A61K31/506 , C07D401/04 , C07D413/04 , C07D417/04 , C07D403/04 , A61K31/5377 , A61P7/02
CPC分类号： C07D211/76 , C07D401/04 , C07D403/04 , C07D413/04 , C07D417/04
摘要： The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I)-: wherein R1 represents an optionally substituted cyclic hydrocarbon group or an optionally substituted heterocyclic group, W represents a bond or an optionally substituted divalent chain hydrocarbon group, a represents 0, 1, or 2, X1 represents an optionally substituted lower alkylene or an optionally substituted lower alkenylene, Y1 represents —C(O)—, —S(O)— or —S(O)2—, A represents a piperazine ring which may be further substituted or a piperidine ring which may be further substituted, X2 represents a bond or an optionally substituted lower alkylene, Y2 represents —C(O)—, —S(O)—, —S(O)2— or —C(═NR7)—, X3 represents an optionally substituted C1-4 alkylene or an optionally substituted C2-4 alkenylene, Z3 represents —N(R4)—, —O— or a bond, Z1 represents —C(R2)(R2′)—, —N(R2)—, etc., and Z2 represents —C(R3)(R3′)—, —N(R3)—, etc., or a salt thereof.
摘要翻译：本发明提供用作治疗血栓形成的药物的环状酰胺衍生物，其由式（I） - 表示：其中R 1表示任选取代的环状烃基或任选取代的杂环基 W表示键或任选取代的二价链烃基，a表示0,1或2，X 1表示任选取代的低级亚烷基或任选取代的低级亚烯基，Y 1 表示-C（O） - ， - S（O） - 或-S（O）2 - ，A表示可以被进一步取代的哌嗪环或可以是 X 2表示键或任选取代的低级亚烷基，Y 2表示-C（O） - ， - S（O） - ， - S（ O）2 - 或-C（-NR 7 H 7） - ，X 3表示任选取代的C 1-4 - 亚烷基或任选取代的C 2-4亚烯基，Z 3表示-N（ R 4） - ，-O-或键，Z 1表示-C（R 2）2（R 2） / R 2） - ， - （R 2） - 等，Z 2表示-C（R 3）（R 3）或其盐，其中R 1，R 2，R 3，R 3，

6. 发明授权

US5889036A Prophylactic or therapeutic drug for renal diseases 失效
标题翻译：肾病预防或治疗药物
公开(公告)号：US5889036A
公开(公告)日：1999-03-30
申请号：US965416
申请日：1997-11-06
申请人： Kohei Nishikawa , Yumiko Shibouta , Keiji Kubo
发明人： Kohei Nishikawa , Yumiko Shibouta , Keiji Kubo
IPC分类号： A61K31/415 , A61K31/4184 , A61K31/4245 , A61P3/08 , A61P3/10 , A61P13/02 , A61P15/00 , A61P29/00 , C07D403/10 , C07D413/10 , C07D417/10 , A61K31/41
CPC分类号： A61K31/4184 , A61K31/415 , A61K31/4245
摘要： This invention relates to prophylactic or therapeutic drug for diabetic nephropathy or glomerulonephritis, comprising, as an active ingredient, a compound or salt thereof represented by general formula (I) ##STR1## wherein R.sup.1 stands for H or an optionally substituted hydrocarbon residue; R.sup.2 stands for an optionally esterified carboxyl group; R.sup.3 stands for a group actually or potentially capable of forming an anion; X shows that the phenylene and phenyl groups bind to each other directly or through a spacer having an atomic chain length of two or less; n stands for 1 or 2; ring A stands for a benzene ring having an optional substituent in addition to R.sup.2 ; Y stands for a bond, --O--, --S(O).sub.m -- (wherein m stands for 0, 1 or 2), or --N(R.sup.4)-- (wherein R.sup.4 stands for H or an optionally substituted alkyl group).
摘要翻译：本发明涉及用于糖尿病性肾病或肾小球肾炎的预防或治疗药物，其包含作为活性成分的由通式（I）表示的化合物或其盐，其中R1代表H或任选取代的烃残基 ; R2代表任选酯化的羧基; R3代表实际上或潜在能够形成阴离子的组; X表示亚苯基和苯基直接或通过原子链长度为2或更小的间隔物彼此结合; n代表1或2; 环A代表除R2之外具有任选取代基的苯环; Y代表键，-O - ， - S（O）m-（其中m代表0,1或2）或-N（R 4） - （其中R 4表示H或任选取代的烷基）。

7. 发明授权

US4935488A Trimethylolheptanes and use thereof 失效
标题翻译：三羟甲基庚烷及其用途
公开(公告)号：US4935488A
公开(公告)日：1990-06-19
申请号：US340791
申请日：1989-04-20
申请人： Toshihiro Omatsu , Yasuo Tokitoh , Noriaki Yoshimura , Masao Ishida , Makoto Yano , Koji Hirai , Yoichi Matsumoto , Keiji Kubo
发明人： Toshihiro Omatsu , Yasuo Tokitoh , Noriaki Yoshimura , Masao Ishida , Makoto Yano , Koji Hirai , Yoichi Matsumoto , Keiji Kubo
IPC分类号： C07C31/22 , C08G63/16 , C08G63/48 , C09D167/00
CPC分类号： C09D167/00 , C07C31/22 , C08G63/16 , C08G63/48
摘要： Novel trimethylolheptanes having three highly reactive hydroxyl groups are provided. They are useful as raw materials for the production of polyesters for use in or as raw materials or modifiers for paints, inks, adhesives, coating compositions and molding resins. Uses for the trimethylolheptanes are also provided.

8. 发明授权

US4920030A Photosensitive coating emulsion for plastic films 失效
标题翻译：塑料薄膜的感光涂料乳液
公开(公告)号：US4920030A
公开(公告)日：1990-04-24
申请号：US298855
申请日：1989-01-19
申请人： Kunihiro Ichimura , Keiji Kubo
发明人： Kunihiro Ichimura , Keiji Kubo
IPC分类号： G03C1/00 , B01D19/04 , G03C1/74 , G03F7/004 , G03F7/038 , G03F7/12 , G03F7/16
CPC分类号： G03F7/004 , G03F7/0388 , G03F7/12
摘要： A photosensitive coating emulsion for a plastic film comprising an emulsionontaining a film-forming polymer and a photocrosslinkable polyvinyl alochol containing a photocrosslinkable constituent unit, which further comprises (1) an aliphatic alcohol having eight carbon atoms as an anti-foaming agent, or (2) a dispersion medium of the emulsion composed of 95 to 50% by weight of water and 5 to 50% by weight of at least one lower aliphatic alcohol selected from the group consisting of methyl, ethyl, n-propyl and i-propyl alcohols, or (3) an acetylenic glycol or alcohol as an anti-foaming agent. These emulsions can give a coating film free from unevenness in coating.
摘要翻译：一种塑料薄膜用感光性涂料乳液，其含有含有成膜性聚合物的乳液和含有可光致交联结构单元的光致交联性聚乙烯醇，其还含有（1）具有8个碳原子的脂肪族醇作为消泡剂，或（ 2）乳液的分散介质，其由95至50重量％的水和5至50重量％的至少一种选自甲基，乙基，正丙基和异丙醇的低级脂族醇组成，或（3）炔二醇或醇作为消泡剂。这些乳液可以赋予涂层不含涂层不均匀的涂膜。

9. 发明授权

US4517271A Electrophotographic CdS photosensitive member with acrylic resin binder 失效
标题翻译：带有丙烯酸树脂粘合剂的电子照相CdS感光构件
公开(公告)号：US4517271A
公开(公告)日：1985-05-14
申请号：US583799
申请日：1984-03-01
申请人： Masaaki Hirooka , Keiji Kubo , Toshiyuki Yoshihara
发明人： Masaaki Hirooka , Keiji Kubo , Toshiyuki Yoshihara
IPC分类号： G03G5/05 , G03G5/087
CPC分类号： G03G5/0546
摘要： An electrophotographic photosensitive member has a photoconductive layer composed of cadmium sulfide bonded with a binder resin which is an acrylic resin having a glass transition point of 15.degree. to 70.degree. C. and an acid value of 10-40.
摘要翻译：电子照相感光构件具有由硫酸镉组成的光导电层，其与粘合剂树脂结合，所述粘合剂树脂是玻璃化转变点为15至70℃，酸值为10-40的丙烯酸树脂。

10. 发明授权

US4082902A Spark-recording type printing method and spark-recording material for use thereof 失效
标题翻译：火花记录式打印方法和使用的火花记录材料
公开(公告)号：US4082902A
公开(公告)日：1978-04-04
申请号：US504709
申请日：1974-09-10
申请人： Akira Suzuki , Keiji Kubo , Suguru Kunitake , Fumiaki Arai
发明人： Akira Suzuki , Keiji Kubo , Suguru Kunitake , Fumiaki Arai
IPC分类号： B41C1/10 , B41M1/08 , B41N3/08 , G01D15/08 , B41N1/00 , G01D15/34
CPC分类号： B41C1/1033 , B41M1/08 , B41N3/08 , Y10T428/31678 , Y10T428/31692 , Y10T428/31699 , Y10T428/31855 , Y10T428/31906 , Y10T428/31993
摘要： The present invention provides a spark-recording type printing method and a spark-recording material for use in the method, which printing method comprises the processes of: forming an image on a spark-recording material by the spark-recording method, said spark-recording material comprising a support and a layer of metal deposited thereon by vacuum evaporation, and, if necessary, being provided with a colored layer interposed between said support and metal layer, and if further necessary, being provided with a protective layer which is easy to desensitize and/or a desensitized layer which requires no desensitization treatment as formed on said metal layer; and conducting offset printing by employing said spark-recording material having an image formed thereon as a master either after subjecting it to desensitization treatment when it is not provided with said desensitized layer or directly when it is provided with said desensitized layer.

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