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1. 发明申请

US20100015671A1 CYCLIC MALTOSYLMALTOSE, CYCLIC MALTOSYMALTOSE-FORMING ENZYME, THEIR PREPARATION AND USES 有权
标题翻译：环状麦芽糖醇，环状麦芽糖醇形成酶，其制备和用途
公开(公告)号：US20100015671A1
公开(公告)日：2010-01-21
申请号：US11941862
申请日：2007-11-16
申请人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
发明人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
IPC分类号： C12P19/18 , C12N9/10
CPC分类号： A61K9/2018 , A21D2/181 , A23L2/52 , A23L2/60 , A23L13/428 , A23L27/33 , A23L33/10 , A61K8/60 , A61Q11/00 , C07H3/06 , C12N9/1048 , C12P19/18
摘要： An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above object by providing a novel cyclic saccharide having a structure of cyclo{>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>}, cyclic maltosylmaltose, novel cyclic maltosylmaltose-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the cyclic maltosylmaltose or a saccharide composition comprising the same, and uses thereof.
摘要翻译：本发明的目的是通过提供一种由葡萄糖组成的新型非还原性糖组成并提供形成非还原性糖的新型酶，提供一种非还原性糖的方法及其制备方法，编码该酶的DNA，重组DNA和包含该DNA的转化体，包含非还原性糖的组合物及其用途。本发明通过提供具有环{> 6）-α-D-吡喃葡萄糖基 - （1,4）-alpha-D-吡喃葡萄糖基 - （1,6）-alpha-D结构的新型环状糖来解决上述目的 - 吡喃葡萄糖基 - （1,4）-alpha-D-吡喃葡萄糖基 - （1>），环状麦芽糖基麦芽糖，新的环状麦芽糖基麦芽糖酶形成酶，其制备方法和方法，编码该酶的DNA，重组DNA和转化体包含该DNA，包含环状麦芽糖麦芽糖的组合物或包含其的糖组合物及其用途。

2. 发明授权

US5916371A Crystalline powdery saccsharide, its preparation and uses 失效
标题翻译：结晶粉状saccsharide，其制备和用途
公开(公告)号：US5916371A
公开(公告)日：1999-06-29
申请号：US985349
申请日：1997-12-04
申请人： Hiroto Chaen , Kazuhisa Mukai , Toshio Miyake
发明人： Hiroto Chaen , Kazuhisa Mukai , Toshio Miyake
IPC分类号： A23G1/30 , A21D2/10 , A21D2/18 , A23B7/10 , A23G1/00 , A23G1/40 , A23G1/56 , A23G3/34 , A23G4/00 , A23G4/10 , A23L1/00 , A23L1/09 , A23L1/164 , A23L1/187 , A23L1/19 , A23L1/218 , A23L1/22 , A23L1/314 , A23L2/38 , A23L2/39 , A23L2/60 , A61K8/00 , A61K8/02 , A61K8/34 , A61K8/60 , A61K8/73 , A61K8/90 , A61K9/00 , A61K9/28 , A61K31/70 , A61K31/7004 , A61K31/7016 , A61K31/702 , A61K47/26 , A61P17/00 , A61Q11/00 , A61Q19/00 , C07H3/02 , C07H3/04 , C07H3/06 , C12N9/24 , C12P19/12 , C13B30/02 , C13B50/00 , C13F1/02 , C13F3/00
CPC分类号： C12P19/12 , A21D2/181 , A23G1/305 , A23G1/40 , A23G1/56 , A23G3/343 , A23G3/346 , A23G4/10 , A23L13/428 , A23L19/20 , A23L2/39 , A23L2/60 , A23L5/00 , A23L7/117 , A23L9/12 , A23L9/22 , A61K47/26 , A61K8/02 , A61K8/0216 , A61K8/60 , A61K9/0014 , A61K9/2826 , A61Q11/00 , A61Q19/00 , C07H3/04 , A23G2200/06 , Y10S514/97
摘要： A stable crystalline powdery saccharide having a crystallinity of 40% or more, less hygroscopicity, satisfactory fluidity, and beneficial handleability, which is obtainable from an aqueous solution, containing trehalose and a different saccharide(s) crystallizable in the presence of trehalose, by crystallizing the trehalose along with the different saccharide(s).
摘要翻译：结晶度为40％以上，稳定的结晶性粉末糖，吸湿性，令人满意的流动性和有益的操作性，可从包含在海藻糖存在下可结晶的海藻糖和不同糖的水溶液获得，通过结晶海藻糖以及不同的糖类。

3. 发明授权

US08759030B2 Process for producing 2-O-alpha-D-glucopyranosyl-L-ascorbic acid 有权
标题翻译：制备2-O-α-D-吡喃葡萄糖基-L-抗坏血酸的方法
公开(公告)号：US08759030B2
公开(公告)日：2014-06-24
申请号：US10523920
申请日：2003-07-07
申请人： Kazuhisa Mukai , Keiji Tsusaki , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
发明人： Kazuhisa Mukai , Keiji Tsusaki , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
IPC分类号： C12P19/44
CPC分类号： C12P19/60
摘要： The object of the present invention is to provide a method and a process for producing 2-O-α-glucopyranosyl-L-ascorbic acid where 5-O-α-glucopyranosyl-L-ascorbic acid and 6-O-α-glucopyranosyl-L-ascorbic acid are not formed or formed in such a small amount that the formation of these can nor be detected. The present invention solves the above object by providing a process for producing 2-O-α-glucopyranosyl-L-ascorbic acid comprising the steps of allowing α-isomaltosyl glucosaccharide-forming enzyme together with or without cyclomaltodextrin glucanotransferase (EC 2.4.1.19) to act on a solution comprising L-ascorbic acid and, an α-glucosyl saccharide to form 2-O-α-glucopyranosyl-L-ascorbic acid and collecting the formed 2-O-α-glucopyranosyl-L-ascorbic acid.
摘要翻译：本发明的目的是提供一种生产2-O-α-吡喃葡萄糖基-L-抗坏血酸的方法和方法，其中5-O-α-吡喃葡萄糖基-L-抗坏血酸和6-O-α-吡喃葡萄糖基 - L-抗坏血酸不是以这样的少量形成或形成，也可以不形成。本发明通过提供一种生产2-O-α-吡喃葡萄糖基-L-抗坏血酸的方法来解决上述目的，其包括以下步骤：将α-异麦芽糖基葡萄糖形成酶与或不与环糊精葡聚糖转移酶（EC 2.4.1.19）一起作用于包含L-抗坏血酸和α-葡萄糖基糖的溶液中以形成2-O-α-吡喃葡萄糖基-L-抗坏血酸并收集形成的2-O-α-吡喃葡萄糖基-L-抗坏血酸。

4. 发明授权

US06126962A Crystalline powdery saccharide, its preparation and uses 有权
标题翻译：结晶性粉末糖，其制备及用途
公开(公告)号：US06126962A
公开(公告)日：2000-10-03
申请号：US219368
申请日：1998-12-23
申请人： Hiroto Chaen , Kazuhisa Mukai , Toshio Miyake
发明人： Hiroto Chaen , Kazuhisa Mukai , Toshio Miyake
IPC分类号： A23G1/30 , A21D2/10 , A21D2/18 , A23B7/10 , A23G1/00 , A23G1/40 , A23G1/56 , A23G3/34 , A23G4/00 , A23G4/10 , A23L1/00 , A23L1/09 , A23L1/164 , A23L1/187 , A23L1/19 , A23L1/218 , A23L1/22 , A23L1/314 , A23L2/38 , A23L2/39 , A23L2/60 , A61K8/00 , A61K8/02 , A61K8/34 , A61K8/60 , A61K8/73 , A61K8/90 , A61K9/00 , A61K9/28 , A61K31/70 , A61K31/7004 , A61K31/7016 , A61K31/702 , A61K47/26 , A61P17/00 , A61Q11/00 , A61Q19/00 , C07H3/02 , C07H3/04 , C07H3/06 , C12N9/24 , C12P19/12 , C13B30/02 , C13B50/00 , A61K7/00
CPC分类号： C12P19/12 , A21D2/181 , A23G1/305 , A23G1/40 , A23G1/56 , A23G3/343 , A23G3/346 , A23G4/10 , A23L13/428 , A23L19/20 , A23L2/39 , A23L2/60 , A23L5/00 , A23L7/117 , A23L9/12 , A23L9/22 , A61K47/26 , A61K8/02 , A61K8/0216 , A61K8/60 , A61K9/0014 , A61K9/2826 , A61Q11/00 , A61Q19/00 , C07H3/04 , A23G2200/06 , Y10S514/97
摘要： A stable crystalline powdery saccharide having a crystallinity of 40% or more, less hygroscopicity, satisfactory fluidity, and beneficial handleability, which is obtainable from an aqueous solution, containing trehalose and a different saccharide(s) crystallizable in the presence of trehalose, by crystallizing the trehalose along with the different saccharide(s).
摘要翻译：结晶度为40％以上，稳定的结晶性粉末糖，吸湿性，令人满意的流动性和有益的操作性，可从包含在海藻糖存在下可结晶的海藻糖和不同糖的水溶液获得，通过结晶海藻糖以及不同的糖类。

5. 发明授权

US07309697B2 Cyclic maltosylmatose 有权
标题翻译：循环麦芽糖
公开(公告)号：US07309697B2
公开(公告)日：2007-12-18
申请号：US10569959
申请日：2004-08-26
申请人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
发明人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
IPC分类号： A61K31/715 , C07H1/00
CPC分类号： A61K9/2018 , A21D2/181 , A23L2/52 , A23L2/60 , A23L13/428 , A23L27/33 , A23L33/10 , A61K8/60 , A61Q11/00 , C07H3/06 , C12N9/1048 , C12P19/18
摘要： An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above object by providing a novel cyclic saccharide having a structure of cyclo{→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→6}, cyclic maltosylmaltose, novel cyclic maltosylmaltose-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the cyclic maltosylmaltose or a saccharide composition comprising the same, and uses thereof.
摘要翻译：本发明的目的是通过提供一种由葡萄糖组成的新型非还原性糖组成并提供形成非还原性糖的新型酶，提供一种非还原性糖的方法及其制备方法，编码该酶的DNA，重组DNA和包含该DNA的转化体，包含非还原性糖的组合物及其用途。本发明通过提供具有环{ - > 6）-α-D-吡喃葡萄糖基 - （1-> 4）-α-D-吡喃葡萄糖基 - （1-> 6） - 结构的新型环状糖来解决上述目的。 α-D-吡喃葡萄糖基 - （1-> 4）-α-D-吡喃葡萄糖基 - （1-> 6），环状麦芽糖基麦芽糖，新型环状麦芽糖基麦芽糖酶形成酶，其制备方法和方法，编码酶，重组DNA和包含该DNA的转化体，包含环状麦芽糖基麦芽糖的组合物或包含其的糖组合物及其用途。

6. 发明申请

US20060216792A1 Process for producing 2-0-alpha-d-glucopyranosyl-l-ascorbic acid 有权
标题翻译：制备2-0-α-d-吡喃葡萄糖基-1-抗坏血酸的方法
公开(公告)号：US20060216792A1
公开(公告)日：2006-09-28
申请号：US10523920
申请日：2003-07-07
申请人： Kazuhisa Mukai , Keiji Tsusaki , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
发明人： Kazuhisa Mukai , Keiji Tsusaki , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
IPC分类号： C12P19/44
CPC分类号： C12P19/60
摘要： The object of the present invention is to provide a method and a process for producing 2-O-α-glucopyranosyl-L-ascorbic acid where 5-O-α-glucopyranosyl-L-ascorbic acid and 6-O-α-glucopyranosyl-L-ascorbic acid are not formed or formed in such a small amount that the formation of these can nor be detected. The present invention solves the above object by providing a process for producing 2-O-α-glucopyranosyl-L-ascorbic acid comprising the steps of allowing α-isomaltosyl glucosaccharide-forming enzyme together with or without cyclomaltodextrin glucanotransferase (EC 2.4.1.19) to act on a solution comprising L-ascorbic acid and, an α-glucosyl saccharide to form 2-O-α-glucopyranosyl-L-ascorbic acid and collecting the formed 2-O-α-glucopyranosyl-L-ascorbic acid.
摘要翻译：本发明的目的是提供一种生产2-O-α-glucopyranosyl-L-抗坏血酸的方法和方法，其中5-O-α-吡喃葡萄糖基-L-抗坏血酸和6-O-α-吡喃葡萄糖基-L- L-抗坏血酸不是以这样的少量形成或形成，也可以不形成。本发明通过提供一种生产2-O-α-吡喃葡萄糖基-L-抗坏血酸的方法来解决上述目的，其包括以下步骤：将α-异麦芽糖基糖糖形成酶与或不与环糊精葡聚糖转移酶（EC 2.4.1.19）一起使用作用于包含L-抗坏血酸和α-葡糖基糖的溶液以形成2-O-α-吡喃葡萄糖基-L-抗坏血酸并收集形成的2-O-α-吡喃葡萄糖基-L-抗坏血酸。

7. 发明授权

US07951530B2 Cyclic maltosylmaltose, cyclic maltosymaltose-forming enzyme, their preparation and uses 有权
标题翻译：循环麦芽糖苷，环状麦芽糖基酶形成酶，其制备和用途
公开(公告)号：US07951530B2
公开(公告)日：2011-05-31
申请号：US11941862
申请日：2007-11-16
申请人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
发明人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
IPC分类号： G01N33/573 , C12Q1/48 , C12P1/00 , C13K7/00 , C07H1/00
CPC分类号： A61K9/2018 , A21D2/181 , A23L2/52 , A23L2/60 , A23L13/428 , A23L27/33 , A23L33/10 , A61K8/60 , A61Q11/00 , C07H3/06 , C12N9/1048 , C12P19/18
摘要： An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above object by providing a novel cyclic saccharide having a structure of cyclo{>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>}, cyclic maltosylmaltose, novel cyclic maltosylmaltose-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the cyclic maltosylmaltose or a saccharide composition comprising the same, and uses thereof.
摘要翻译：本发明的目的是通过提供一种由葡萄糖组成的新型非还原性糖组成并提供形成非还原性糖的新型酶，提供一种非还原性糖的方法及其制备方法，编码该酶的DNA，重组DNA和包含该DNA的转化体，包含非还原性糖的组合物及其用途。本发明通过提供具有环{（6）-α-D-吡喃葡萄糖基 - （1,4）-α-D-吡喃葡萄糖基 - （1,6）-α-D结构的新型环状糖来解决上述目的 - 吡喃葡萄糖基 - （1> 4）-α-D-吡喃葡萄糖基 - （1>），环状麦芽糖基麦芽糖，新型环状麦芽糖基麦芽糖酶形成酶，其制备方法和方法，编码该酶的DNA，重组DNA和转化体包含该DNA，包含环状麦芽糖麦芽糖的组合物或包含其的糖组合物及其用途。

8. 发明申请

US20070066565A1 Cyclic maltosylmatose 有权
公开(公告)号：US20070066565A1
公开(公告)日：2007-03-22
申请号：US10569959
申请日：2004-08-26
申请人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
发明人： Kazuhisa Mukai , Hikaru Watanabe , Tomoyuki Nishimoto , Michio Kubota , Shigeharu Fukuda , Toshio Miyake
IPC分类号： C12P19/04 , C07H21/04 , A61K31/715 , C12P21/06 , C12N9/10
CPC分类号： A61K9/2018 , A21D2/181 , A23L2/52 , A23L2/60 , A23L13/428 , A23L27/33 , A23L33/10 , A61K8/60 , A61Q11/00 , C07H3/06 , C12N9/1048 , C12P19/18
摘要： An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above object by providing a novel cyclic saccharide having a structure of cyclo{→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→6}, cyclic maltosylmaltose, novel cyclic maltosylmaltose-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the cyclic maltosylmaltose or a saccharide composition comprising the same, and uses thereof.

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