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1. 发明申请

US20170073354A1 PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS 审中-公开
标题翻译：作为HIV蛋白酶抑制剂的哌嗪衍生物
公开(公告)号：US20170073354A1
公开(公告)日：2017-03-16
申请号：US15124635
申请日：2015-03-06
申请人： Jurgen SCHULZ , Peter D. WILLIAMS , John A. MCCAULEY , Christopher J. BUNGARD , David Jonathan BENNETT , Sherman T. WADDELL , Gregori J. MORRIELLO , Lehua CHANG , Michael P. DWYER , Katharine M. HOLLOWAY , Alejandro CRESPO , Xin-Jie CHU , Catherine WISCOUNT , Marie H. LOUGHRAN , Jesse J. MANIKOWSKI , Kartik M. KEERTIKAR , Bin HU , Bin ZHONG , Tao JI , Merck Sharp & Dohme Corp. , MSD R&D (China) Co., Ltd.
发明人： Peter D. Williams , John A. McCauley , Christopher J. Bungard , David Jonathan Bennett , Sherman T. Waddell , Gregori J. Morriello , Lehua Chang , Michael P. Dwyer , M. Katharine Holloway , Alejandro Crespo , Xin-Jie Chu , Catherine Wiscount , H. Marie Loughran , Jesse J. Manikowski , Jurgen Schulz , Kartik M. Keertikar , Bin Hu , Bin Zhong , Tao Ji
IPC分类号： C07D513/08 , A61K31/554 , A61K45/06
CPC分类号： C07D513/08 , A61K31/554 , A61K45/06
摘要： The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.
摘要翻译：本发明涉及含有该化合物的式I药物组合物的化合物及其在抑制HIV蛋白酶，抑制HIV复制，预防HIV感染，HIV感染治疗和预防，治疗和延迟艾滋病的发病或进展。

2. 发明申请

US20170071278A1 WINGED VISOR STIFFENER FOR HAT'S BRIM 审中-公开
公开(公告)号：US20170071278A1
公开(公告)日：2017-03-16
申请号：US15341802
申请日：2016-11-02
申请人： Jurgen Schulz , Richard Knight
发明人： Jurgen Schulz , Richard Knight
IPC分类号： A42B1/06 , A42C5/04 , A42B1/18 , A42B1/02
CPC分类号： A42B1/063 , A42B1/045 , A42B1/062 , A42C5/04
摘要： A winged visor stiffener for a hat's bill. A flat horizontal front section is connected to two angled offset sections. Two flat horizontal wings are connected to the two angled offset sections. The winged visor stiffener is sewn into the hat's bill via a plurality of rows of tight stitching. The winged visor stiffener provides protection to the wearer's face from the sun while optimizing peripheral vision and prevents the bill from flopping up or down in wet and windy conditions.
摘要翻译：帽子帐单的翼形遮阳板加强筋。平坦的水平前部连接到两个倾斜的偏移部分。两个扁平的水平翼连接到两个倾斜的偏移部分。翼形遮阳板加强件通过多排紧密缝合缝合到帽子的帐单中。翼形遮阳板扶强材为佩戴者的脸部提供保护，同时优化周边视力，防止帐单在潮湿和多风的条件下上下颠倒。

3. 发明授权

US08377240B2 Method for the production of a metal-ceramic substrate or copper-ceramic substrate, and support to be used in said method 有权
标题翻译：制造金属陶瓷基板或铜陶瓷基板的方法以及用于所述方法的支撑体
公开(公告)号：US08377240B2
公开(公告)日：2013-02-19
申请号：US11666426
申请日：2005-10-05
申请人： Jurgen Schulz-Harder , Andreas Karl Frischmann , Alexander Rogg , Karl Exel
发明人： Jurgen Schulz-Harder , Andreas Karl Frischmann , Alexander Rogg , Karl Exel
IPC分类号： C03B29/00
CPC分类号： C04B37/021 , B32B18/00 , B32B2311/12 , B32B2315/02 , C04B2235/6584 , C04B2235/9607 , C04B2237/341 , C04B2237/343 , C04B2237/365 , C04B2237/407 , C04B2237/54 , C04B2237/56 , C04B2237/562 , C04B2237/704 , H01L23/3735 , H01L2924/0002 , H05K1/0306 , H05K3/022 , H05K2201/0116 , H05K2201/0355 , H05K2203/016 , H01L2924/00
摘要： A method is disclosed for producing metal-ceramic substrates that are metallized on both sides by using the direct bonding process. According to the method, at least one DCB stack made from first and a second metal layer and a ceramic layer located between said metal layers is formed on a separating layer of a support by heating to a direct bonding temperature. At least one of the metal layers rests against the separating layer during the bonding process, said separating layer being composed of a porous layer or coating made of a separating layer material from the group comprising mullite, Al2O3, TiO3, ZrO2, MgO, CaO CaCO2 or a mixture of at least two of said materials.
摘要翻译：公开了一种用于制造通过使用直接粘合工艺在两侧金属化的金属陶瓷基板的方法。根据该方法，通过加热到直接接合温度，在支撑体的分离层上形成由第一和第二金属层制成的至少一个DCB堆叠和位于所述金属层之间的陶瓷层。在接合过程中，至少有一层金属层靠在分离层上，所述分离层由多孔层或由莫来石，Al 2 O 3，TiO 3，ZrO 2，MgO，CaO CaCO 2组成的分离层材料制成的涂层或至少两种所述材料的混合物。

4. 发明授权

US08328157B2 Electromagnetic hydraulic valve 有权
标题翻译：电磁液压阀
公开(公告)号：US08328157B2
公开(公告)日：2012-12-11
申请号：US12763421
申请日：2010-04-20
申请人： Jurgen Schulz , Marco Meisborn
发明人： Jurgen Schulz , Marco Meisborn
IPC分类号： F16K31/02
CPC分类号： F16K31/0655 , B60T8/363 , F16K31/0693
摘要： An electromagnetic hydraulic valve (1) is provided having a valve housing (2) with a pressurized hydraulic medium inlet channel (24), a pressurized hydraulic medium outlet channel (25), a magnet coil (3), and a valve seat (23), with a magnet armature (9) that can be excited by the magnet coil and a valve tappet (10, 10′) fixed on this armature. A valve-closing element (13) is activated by the valve tappet and that blocks the connection between the pressurized hydraulic medium channels for contact on the valve seat. The magnet armature with the valve tappet and the valve-closing element are guided so that they can move longitudinally in the valve housing and the valve tappet and the valve-closing element contact each other with facing longitudinal end sides (26, 27) in a way that is free from tensile forces. Here, one annular, continuous lobe or several lobes (28, 28′) separated from each other are formed on the longitudinal end side of the valve tappet, which span a contact plane running perpendicular to a longitudinal direction of movement for the longitudinal end side of the valve-closing element.
摘要翻译：提供一种电磁液压阀（1），其具有带有加压液压介质入口通道（24）的阀壳体（2），加压液压介质出口通道（25），磁体线圈（3）和阀座（23）），具有可被磁体线圈激励的磁体电枢（9）和固定在该电枢上的阀挺杆（10,10'）。阀关闭元件（13）由阀挺杆启动，并且阻塞用于接触阀座的加压液压介质通道之间的连接。具有阀挺杆和闭阀元件的磁体衔铁被引导，使得它们可以在阀壳体中纵向运动，并且阀挺杆和阀关闭元件以相对的纵向端侧（26,27）彼此接触，没有拉力的方式。这里，在阀挺杆的纵向端侧上形成有一个环形连续的叶片或多个彼此分离的叶片（28,28'），其横跨垂直于纵向端侧的纵向移动方向的接触平面的阀关闭元件。

5. 发明授权

US08258293B2 Tetrahydroquinoline derivatives 有权
公开(公告)号：US08258293B2
公开(公告)日：2012-09-04
申请号：US13268214
申请日：2011-10-07
申请人： Nicole Corine Renee Van Straten , Rudolf Gijsbertus Van Someren , Jurgen Schulz
发明人： Nicole Corine Renee Van Straten , Rudolf Gijsbertus Van Someren , Jurgen Schulz
IPC分类号： C07D215/08 , C07D215/12 , C07D215/20 , C07D215/38 , C07D215/48 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12
CPC分类号： C07D215/38 , A61K31/47 , A61K31/4709 , C07D215/08 , C07D215/20 , C07D215/48
摘要： The present invention relates to tetrahydroquinoline derivatives having general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is formyl, (1-6C)alkylcarbonyl or (1-6C)alkylsulfonyl; R2 and R3 are H or (1-4C)alkyl; R4 is phenyl; R5 is (1-4C)alkyl; Y—X is C(O)—O, S(O)2-O, NHC(O)—O, NHC(S)—O, OC(O)—O, bond-O, C(O)—NH, S(O)2-NH, NHC(O)—NH, NHC(S)—NH, OC(O)—NH, bond-NH, NH—C(O), O—C(O), NH—S(O)2, or O—S(O)2 or Y—X is a bond; R6 is H, trifluoromethyl, (1-6C)alkyl, 1- or 2-adamantyl(1-4C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, (3-9C)heteroaryl, (3-6C)cycloalkyl, (2-6C)heterocycloalkyl, (1-4C)alkylthio(1-4C)alkyl, (6-10C)aryl(1-4C)alkyl, (3-9C)heteroaryl(1-4C)alkyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl(1-4C)alkyl, R8,R9-aminocarbonyl(1-4C)alkyl, R8,R9-amino(1-4C)alkyl, R8-oxycarbonyl(1-4C)alkyl, R8-oxy(1-4C)alkyl, R8-carbonyl(1-4C)alkyl or (6-10C)aryl; R7 is H, (1-4C)alkyl, (1-4C)alkoxy, halogen, trifluoromethyl, cyano, nitro, hydroxyl; and R8 and/or R9 is H, (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (6-10C)aryl, (3-9C)heteroaryl, (6-10C)aryl(1-4C)alkyl, (3-9C)heteroaryl(1-4C)alkyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl(1-4C)alkyl, (1-4C)(di)alkylamino(1-4C)alkyl, (1-4C)alkoxy(1-4C)alkyl, (1-4C)alkylthio(1-4C)alkyl, (1-4C)alkylcarbonylamino(1-4C)alkyl, (1-4C)alkoxycarbonyl(1-4C)alkyl, (1-4C)alkoxycarbonylamino(1-4C)alkyl, (3-6C)cycloalkyl, (2-6C)heterocycloalkyl, or R8 and R9 may be joined in a (2-6C)heterocycloalkyl ring. The present invention also relates to pharmaceutical compositions comprising said derivatives and the use of these derivatives to control fertility.

6. 发明申请

US20090213547A1 Electrical Module 有权
标题翻译：电气模块
公开(公告)号：US20090213547A1
公开(公告)日：2009-08-27
申请号：US11992986
申请日：2006-07-26
申请人： Jurgen Schulz-Harder , Andreas Meyer
发明人： Jurgen Schulz-Harder , Andreas Meyer
IPC分类号： H05K7/20
CPC分类号： H05K7/20254 , F28F2210/02 , H01L23/4012 , H01L23/473 , H01L24/48 , H01L25/071 , H01L25/072 , H01L2224/48137 , H01L2924/00014 , H01L2924/01068 , H01L2924/1301 , H01L2924/13033 , H01L2924/13055 , H01L2924/1627 , H01L2924/181 , H01L2924/00 , H01L2224/45099
摘要： The invention relates to a module with a number of electrical or electronic components or switching circuits provided on a common cooler structure flowed through by a cooling medium. The entire cooler structure is made up of at least two plate-shaped coolers, which are arranged parallel to one another in an interspaced manner and which are flowed through by the cooling medium.
摘要翻译：本发明涉及一种具有多个电气或电子部件的模块或设置在由冷却介质流过的公共冷却器结构上的开关电路。整个冷却器结构由至少两个板状冷却器组成，板状冷却器以间隔方式彼此平行地布置并且由冷却介质流过。

7. 发明申请

US20080189948A1 Heat sink in the form of a heat pipe and process for manufacturing such a heat sink 有权
标题翻译：热管形式的散热器和用于制造这种散热器的工艺
公开(公告)号：US20080189948A1
公开(公告)日：2008-08-14
申请号：US12081622
申请日：2008-04-18
申请人： Jurgen Schulz-Harder
发明人： Jurgen Schulz-Harder
IPC分类号： B21D53/02
CPC分类号： F28D15/04 , H01L2224/48091 , H01L2224/48227 , H01L2924/19107 , Y10T29/49353 , Y10T29/49377 , Y10T29/53113 , H01L2924/00014
摘要： A heat sink designed as a heat pipe has an interior space in a body of the heat sink that is closed toward the outside. The interior space has at least one vapor channel and at least one fluid space connected with the vapor space and having a porous or capillary structure. The heat pipe is made using the DCB process to connect each end of posts within the interior space directly with one of the two opposing walls forming the interior space.
摘要翻译：设计为热管的散热器在散热器的主体中具有向外部封闭的内部空间。内部空间具有至少一个蒸汽通道和至少一个与蒸气空间连接并具有多孔或毛细管结构的流体空间。使用DCB工艺制造热管，以将内部空间内的柱的每个端部直接连接到形成内部空间的两个相对壁中的一个。

8. 发明申请

US20060263584A1 Composite material, electrical circuit or electric module 审中-公开
标题翻译：复合材料，电路或电气模块
公开(公告)号：US20060263584A1
公开(公告)日：2006-11-23
申请号：US10554496
申请日：2004-04-20
申请人： Jurgen Schulz-Harder , Ernst Hammel
发明人： Jurgen Schulz-Harder , Ernst Hammel
IPC分类号： C22C49/14 , C22C9/00
CPC分类号： H01L23/49877 , B22F2998/10 , B22F2999/00 , C22C49/14 , C22C2204/00 , H01L23/373 , H01L23/3735 , H01L24/48 , H01L2224/05599 , H01L2224/45099 , H01L2224/48091 , H01L2224/48227 , H01L2224/85399 , H01L2924/00014 , H01L2924/01019 , H01L2924/0102 , H01L2924/01079 , H01L2924/01322 , H01L2924/09701 , H01L2924/3025 , H05K1/0306 , H05K3/0058 , H05K3/38 , Y10T428/249924 , C22C47/06 , C22C47/08 , B22F1/004 , B22F1/0018 , H01L2224/45015 , H01L2924/207
摘要： The invention relates to a novel composite material, especially for applications in the field of electrical engineering. Said novel material has a thermal coefficient of expansion that is smaller than 12×10−6 K−1 in at least two axes of a three-dimensional system that are perpendicular in relation to each other.
摘要翻译：本发明涉及一种新型复合材料，特别适用于电气工程领域。所述新型材料在三维系统的至少两个轴上的热膨胀系数小于12×10 -6 K -1，其相对于彼此。

9. 发明申请

US20060117561A1 Conductor board and method for producing a conductor board 失效
公开(公告)号：US20060117561A1
公开(公告)日：2006-06-08
申请号：US11292656
申请日：2005-12-02
申请人： Jurgen Schulz-Harder , Andreas Meyer
发明人： Jurgen Schulz-Harder , Andreas Meyer
IPC分类号： H01R43/04 , H01R43/00 , H05K1/11 , H05K1/00
CPC分类号： H05K3/4084 , H05K1/0306 , H05K3/321 , H05K3/328 , H05K3/3484 , H05K3/4046 , H05K2201/0355 , H05K2201/0394 , H05K2201/068 , H05K2201/10416 , H05K2203/0195 , H05K2203/063 , Y10T29/49117 , Y10T29/49124 , Y10T29/49144 , Y10T29/49218
摘要： The conductor board has at least one layer of a dielectric provided areally on two mutually opposed faces with at least one metalization on each. There is at least one through contacting in the region of an aperture. The metalizations are applied to cover at least one aperture and are electrically connected to each other through the aperture.

10. 发明授权

US07055016B2 Computer system including a memory controller configured to perform pre-fetch operations 有权
标题翻译：包括被配置为执行预取操作的存储器控制器的计算机系统
公开(公告)号：US07055016B2
公开(公告)日：2006-05-30
申请号：US10426565
申请日：2003-04-30
申请人： Andrew E. Phelps , Anders Landin , Jurgen Schulz
发明人： Andrew E. Phelps , Anders Landin , Jurgen Schulz
IPC分类号： G06F9/32
CPC分类号： G06F12/0862 , G06F12/0215
摘要： A computer system including a memory controller configured to perform pre-fetch operations. A computer system includes a first system memory, a second system memory and a first and a second memory controller which are coupled to the first and second system memories, respectively. Each system memory may include at least one memory module including volatile storage. The first memory controller may be configured read data from the first system memory corresponding to an address of a current memory request. Further the second memory controller may be configured to selectively pre-fetch data from the second system memory depending upon selected address bits of the address of the current memory request.
摘要翻译：一种包括被配置为执行预取操作的存储器控制器的计算机系统。计算机系统包括分别耦合到第一和第二系统存储器的第一系统存储器，第二系统存储器以及第一和第二存储器控制器。每个系统存储器可以包括至少一个包括易失性存储器的存储器模块。第一存储器控制器可以被配置为从对应于当前存储器请求的地址的第一系统存储器读取数据。此外，第二存储器控制器可以被配置为根据当前存储器请求的地址的所选择的地址位选择性地从第二系统存储器预取数据。

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