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1. 外观设计

USD656609S1 Swab 有权
标题翻译：拭子
公开(公告)号：USD656609S1
公开(公告)日：2012-03-27
申请号：US29386293
申请日：2011-02-28
申请人： Juan J. Perez , Stormy L. Perez , Billie Lane Walker
设计人： Juan J. Perez , Stormy L. Perez , Billie Lane Walker
CPC分类号： A61F11/006 , A61B2017/246 , A61H21/00 , A61H2015/0042 , A61H2201/105 , A61H2205/023

2. 发明授权

US07951106B1 Personal hygiene device and method for application of medication 失效
标题翻译：个人卫生装置及药物使用方法
公开(公告)号：US07951106B1
公开(公告)日：2011-05-31
申请号：US12477304
申请日：2009-06-03
申请人： Juan J. Perez , Stormy L. Perez , Billie Lane Walker
发明人： Juan J. Perez , Stormy L. Perez , Billie Lane Walker
IPC分类号： A61F13/20
CPC分类号： A61F11/006 , A61B2017/246 , A61H21/00 , A61H2015/0042 , A61H2201/105 , A61H2205/023
摘要： A personal hygiene device for cleaning orifices, such as the nostrils, one at a time without batteries or power. The device can further be usable in the application of medications, which can be disposed in a tubular body of the device for exact dosage amounts. The personal hygiene device can be reusable without deformation.
摘要翻译：用于清洁孔的个人卫生设备，例如鼻孔，一次一个没有电池或电源。该装置可以进一步用于药物的施用，药物可以设置在装置的管状体中用于精确的剂量。个人卫生装置可以重复使用而不变形。

3. 发明申请

US20110082095A1 NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 158P3D2 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效
标题翻译：核酸和对照蛋白158P3D2有用的治疗和检测癌症
公开(公告)号：US20110082095A1
公开(公告)日：2011-04-07
申请号：US12899433
申请日：2010-10-06
申请人： ARTHUR B. RAITANO , AYA JAKOBOVITS , PIA M. CHALLITA-EID , STEVEN B. KANNER , WANGMAO GE , JUAN J. PEREZ-VILLAR , ROBERT KENDALL MORRISON
发明人： ARTHUR B. RAITANO , AYA JAKOBOVITS , PIA M. CHALLITA-EID , STEVEN B. KANNER , WANGMAO GE , JUAN J. PEREZ-VILLAR , ROBERT KENDALL MORRISON
IPC分类号： A61K38/16 , C07H21/04 , C12N15/63 , C12N5/10 , C12P21/02 , C07K14/00 , G01N33/53 , A61P35/00
CPC分类号： C07K14/4748 , A61K39/00 , C07K16/30
摘要： A novel gene 158P3D2 and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization.
摘要翻译：描述了一种新型基因158P3D2及其编码的蛋白及其变体，其中158P3D2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，158P3D2提供诊断，预后，预防和/ 或癌症的治疗靶标。 158P3D2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与158P3D2反应的抗体或T细胞可用于主动或被动免疫。

4. 外观设计

USD631957S1 Swab 有权
标题翻译：拭子
公开(公告)号：USD631957S1
公开(公告)日：2011-02-01
申请号：US29338014
申请日：2009-06-03
申请人： Juan J. Perez , Stormy L. Perez , Billie Lane Walker
设计人： Juan J. Perez , Stormy L. Perez , Billie Lane Walker
CPC分类号： A61F11/006

5. 发明授权

US07811575B2 Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer 失效
标题翻译：题为158P3D2的核酸和相应的蛋白质可用于治疗和检测癌症
公开(公告)号：US07811575B2
公开(公告)日：2010-10-12
申请号：US10994106
申请日：2004-11-19
申请人： Arthur B. Raitano , Aya Jakobovits , Pia M. Challita-Eid , Steven B. Kanner , Wangmao Ge , Juan J. Perez-Villar , Robert Kendall Morrison
发明人： Arthur B. Raitano , Aya Jakobovits , Pia M. Challita-Eid , Steven B. Kanner , Wangmao Ge , Juan J. Perez-Villar , Robert Kendall Morrison
IPC分类号： A61K39/00
CPC分类号： C07K14/4748 , A61K39/00 , C07K16/30
摘要： A novel gene 158P3D2 and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization.
摘要翻译：描述了一种新型基因158P3D2及其编码的蛋白及其变体，其中158P3D2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，158P3D2提供诊断，预后，预防和/ 或癌症的治疗靶标。 158P3D2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与158P3D2反应的抗体或T细胞可用于主动或被动免疫。

6. 发明申请

US20090042226A1 Identification and cloning of a full-length human CLNK-related gene, MIST (MAST cell immunoreceptor signal transducer) 有权
标题翻译：鉴定和克隆全长人类CLNK相关基因MIST（MAST细胞免疫受体信号转导子）
公开(公告)号：US20090042226A1
公开(公告)日：2009-02-12
申请号：US12231623
申请日：2008-09-04
申请人： Juan J. Perez-Villar , Han Chang , Steven B. Kanner , Gena S. Whitney , Yuli Wu , Wen-Pin Yang
发明人： Juan J. Perez-Villar , Han Chang , Steven B. Kanner , Gena S. Whitney , Yuli Wu , Wen-Pin Yang
IPC分类号： G01N33/53 , C07K16/18 , C12N5/06 , C12N9/00
CPC分类号： C07K14/47 , A01K2217/05 , Y10S435/81
摘要： The present invention describes a newly discovered full-length polynucleotide encoding an SH2 domain-containing adapter protein, called human MIST, cloned, isolated and identified from a human spleen cDNA library. Also described are the MIST polypeptide sequence, expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Novel splice variant forms of human MIST are provided. Methods for screening for modulators, particularly inhibitors, of the MIST protein and use of the human MIST polynucleotide and polypeptide for therapeutics and diagnostics are described.
摘要翻译：本发明描述了一种新发现的全长多核苷酸，其编码含有SH2结构域的衔接蛋白，称为人MIST，从人脾cDNA文库克隆，分离和鉴定。还描述了与本发明的多核苷酸和/或多肽相关的MIST多肽序列，表达载体，宿主细胞，激动剂，拮抗剂，反义分子和抗体。提供人类MIST的新型剪接变体形式。描述了用于筛选MIST蛋白的调节剂，特别是抑制剂的方法以及人MIST多核苷酸和多肽用于治疗和诊断的用途。

7. 发明授权

US07442770B2 Human clnk-related polypeptide, MIST (Mast Cell Immunoreceptor Signal Transducer) 有权
标题翻译：人类相关多肽MIST（Mast Cell Immunoreceptor Signal Transducer）
公开(公告)号：US07442770B2
公开(公告)日：2008-10-28
申请号：US11640775
申请日：2006-12-18
申请人： Juan J. Perez-Villar , Han Chang , Wen-Pin Yang , Yuli Wu , Gena S. Whitney , Steven B. Kanner
发明人： Juan J. Perez-Villar , Han Chang , Wen-Pin Yang , Yuli Wu , Gena S. Whitney , Steven B. Kanner
IPC分类号： C07K14/435 , C12N15/12 , C12N15/63
CPC分类号： C07K14/47 , A01K2217/05 , Y10S435/81
摘要： The present invention describes a newly discovered full-length polynucleotide encoding an SH2 domain-containing adapter protein, called human MIST, cloned, isolated and identified from a human spleen cDNA library. Also described are the MIST polypeptide sequence, expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Novel splice variant forms of human MIST are provided. Methods for screening for modulators, particularly inhibitors, of the MIST protein and use of the human MIST polynucleotide and polypeptide for therapeutics and diagnostics are described.
摘要翻译：本发明描述了一种新发现的全长多核苷酸，其编码含有SH2结构域的衔接蛋白，称为人MIST，从人脾cDNA文库克隆，分离和鉴定。还描述了与本发明的多核苷酸和/或多肽相关的MIST多肽序列，表达载体，宿主细胞，激动剂，拮抗剂，反义分子和抗体。提供人类MIST的新型剪接变体形式。描述了用于筛选MIST蛋白的调节剂，特别是抑制剂的方法以及人MIST多核苷酸和多肽用于治疗和诊断的用途。

8. 发明授权

US07241590B2 Identification and cloning of a full-length human Clnk-related gene, MIST (mast cell immunoreceptor signal transducer) 有权
标题翻译：鉴定和克隆全长人类Clnk相关基因MIST（肥大细胞免疫受体信号转导子）
公开(公告)号：US07241590B2
公开(公告)日：2007-07-10
申请号：US09966955
申请日：2001-09-28
申请人： Juan J. Perez-Villar , Han Chang , Wen-Pin Yang , Yuli Wu , Gena S. Whitney , Steven B. Kanner
发明人： Juan J. Perez-Villar , Han Chang , Wen-Pin Yang , Yuli Wu , Gena S. Whitney , Steven B. Kanner
IPC分类号： C12N5/10 , C12N15/12 , C12N15/62 , C12N15/63
CPC分类号： C07K14/47 , A01K2217/05 , Y10S435/81
摘要： The present invention describes a newly discovered full-length polynucleotide encoding an SH2 domain-containing adapter protein, called human MIST, cloned, isolated and identified from a human spleen cDNA library. Also described are the MIST polypeptide sequence, expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Novel splice variant forms of human MIST are provided. Methods for screening for modulators, particularly inhibitors, of the MIST protein and use of the human MIST polynucleotide and polypeptide for therapeutics and diagnostics are described.
摘要翻译：本发明描述了一种新发现的全长多核苷酸，其编码含有SH2结构域的衔接蛋白，称为人MIST，从人脾cDNA文库克隆，分离和鉴定。还描述了与本发明的多核苷酸和/或多肽相关的MIST多肽序列，表达载体，宿主细胞，激动剂，拮抗剂，反义分子和抗体。提供人类MIST的新型剪接变体形式。描述了用于筛选MIST蛋白的调节剂，特别是抑制剂的方法以及人MIST多核苷酸和多肽用于治疗和诊断的用途。

9. 发明授权

US06457788B1 Computer hood latching system 失效
标题翻译：电脑盖闩锁系统
公开(公告)号：US06457788B1
公开(公告)日：2002-10-01
申请号：US09679089
申请日：2000-10-04
申请人： Juan J. Perez , Donal J. Hall , Jeff A. Lambert
发明人： Juan J. Perez , Donal J. Hall , Jeff A. Lambert
IPC分类号： A47G2900
CPC分类号： G06F1/181
摘要： A protective assembly for housing and accessing components is featured. The protective assembly has a chassis, a cover, and a flexible latch for securing the cover to the chassis. The flexible latch has a latch and the base has a catch. The base includes a fulcrum. The fulcrum is used during removal of the cover to pivot the latch so that the latch is brought free of the catch.
摘要翻译：具有外壳和接入部件的保护组件。保护组件具有底盘，盖和用于将盖固定到底盘的柔性闩锁。柔性闩锁具有闩锁，并且底座具有卡扣。底座包括支点。在拆卸盖子期间使用支点以枢转闩锁，使得闩锁没有卡扣。

10. 发明授权

US08188936B2 Context aware auxiliary display platform and applications 有权
标题翻译：上下文意识辅助显示平台和应用
公开(公告)号：US08188936B2
公开(公告)日：2012-05-29
申请号：US12415979
申请日：2009-03-31
申请人： Andrew J. Fuller , Matthew P. Rhoten , Juan J. Perez , Christopher A. Schoppa , Curt A. Steeb , Niels van Dongen
发明人： Andrew J. Fuller , Matthew P. Rhoten , Juan J. Perez , Christopher A. Schoppa , Curt A. Steeb , Niels van Dongen
IPC分类号： G09G5/00
CPC分类号： G06F9/542 , G06F2209/544 , H04M1/72569 , H04M2250/12
摘要： Described is a mechanism by which application programs (or plug-ins) and an auxiliary service adjust the output and/or data available for output on an auxiliary device based on changes detected in the current context of the auxiliary display. Context sensors detect and report changes in context, whereby some action is taken with respect to what information is displayed or can be displayed on the auxiliary display device. Examples of context data that can change include the physical location of the display, detected movement or motion data, presence of a particular user or others, power state, network connectivity status, privacy status and so forth. The auxiliary device can have context as to its position relative to the main display. Information sensitivity levels may be used to specify whether an application program's data can be displayed, based on the perceived sensitivity of the information and the user's current context.
摘要翻译：描述了应用程序（或插件）和辅助服务器根据在辅助显示器的当前上下文中检测到的改变来调整可用于在辅助设备上输出的输出和/或数据的机制。上下文传感器检测并报告上下文中的变化，由此对于在辅助显示设备上显示或可以显示的信息采取一些动作。可以改变的上下文数据的示例包括显示器的物理位置，检测到的移动或运动数据，特定用户或其他用户的存在，电力状态，网络连接状态，隐私状态等。辅助设备可以具有关于其相对于主显示器的位置的上下文。信息敏感度级别可以用于指定应用程序的数据是否可以根据信息感知的敏感性和用户的当前上下文来显示。

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